ATE478696T1 - Polymerbeschichtung für medizinische geräte - Google Patents

Polymerbeschichtung für medizinische geräte

Info

Publication number
ATE478696T1
ATE478696T1 AT06025591T AT06025591T ATE478696T1 AT E478696 T1 ATE478696 T1 AT E478696T1 AT 06025591 T AT06025591 T AT 06025591T AT 06025591 T AT06025591 T AT 06025591T AT E478696 T1 ATE478696 T1 AT E478696T1
Authority
AT
Austria
Prior art keywords
layer
polymer layer
lactone
silane derivative
functional groups
Prior art date
Application number
AT06025591T
Other languages
English (en)
Inventor
Frantisek Rypacek
Monika Lapcikova
Ludka Machova
Original Assignee
Gilead Palo Alto Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Palo Alto Inc filed Critical Gilead Palo Alto Inc
Application granted granted Critical
Publication of ATE478696T1 publication Critical patent/ATE478696T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076—Chemical modification of the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
    • Y10T428/139—Open-ended, self-supporting conduit, cylinder, or tube-type article
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
    • Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
    • Y10T428/139—Open-ended, self-supporting conduit, cylinder, or tube-type article
    • Y10T428/1393—Multilayer [continuous layer]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31652—Of asbestos
    • Y10T428/31663—As siloxane, silicone or silane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31786—Of polyester [e.g., alkyd, etc.]
AT06025591T 2002-02-15 2003-02-14 Polymerbeschichtung für medizinische geräte ATE478696T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35757302P 2002-02-15 2002-02-15

Publications (1)

Publication Number Publication Date
ATE478696T1 true ATE478696T1 (de) 2010-09-15

Family

ID=27734757

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03739424T ATE348643T1 (de) 2002-02-15 2003-02-14 Polymerüberzug für medizinische vorrichtungen
AT06025591T ATE478696T1 (de) 2002-02-15 2003-02-14 Polymerbeschichtung für medizinische geräte

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03739424T ATE348643T1 (de) 2002-02-15 2003-02-14 Polymerüberzug für medizinische vorrichtungen

Country Status (24)

Country Link
US (4) US7160592B2 (de)
EP (2) EP1492581B1 (de)
JP (1) JP4472348B2 (de)
KR (1) KR20040097126A (de)
CN (2) CN1279984C (de)
AT (2) ATE348643T1 (de)
AU (2) AU2003215495B2 (de)
CA (1) CA2476431A1 (de)
CY (1) CY1107549T1 (de)
DE (2) DE60333955D1 (de)
DK (2) DK1764118T3 (de)
ES (2) ES2349424T3 (de)
HK (2) HK1072205A1 (de)
HU (1) HUP0402591A2 (de)
IL (1) IL163535A0 (de)
MX (1) MXPA04007898A (de)
NO (1) NO20043843L (de)
NZ (1) NZ534682A (de)
PL (1) PL371517A1 (de)
PT (2) PT1764118E (de)
RU (1) RU2308976C2 (de)
SI (2) SI1764118T1 (de)
WO (1) WO2003068289A1 (de)
ZA (1) ZA200406448B (de)

Families Citing this family (224)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU716005B2 (en) * 1995-06-07 2000-02-17 Cook Medical Technologies Llc Implantable medical device
US7713297B2 (en) * 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US7220276B1 (en) * 2000-03-06 2007-05-22 Surmodics, Inc. Endovascular graft coatings
US6512072B1 (en) 2000-06-12 2003-01-28 Dow Corning Corporation Fast cure film forming formulation
US20070027535A1 (en) * 2005-07-28 2007-02-01 Cook Incorporated Implantable thromboresistant valve
US8038708B2 (en) * 2001-02-05 2011-10-18 Cook Medical Technologies Llc Implantable device with remodelable material and covering material
AU2002345328A1 (en) 2001-06-27 2003-03-03 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US8741378B1 (en) * 2001-06-27 2014-06-03 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device
US20060093771A1 (en) * 2002-02-15 2006-05-04 Frantisek Rypacek Polymer coating for medical devices
MXPA05003238A (es) * 2002-09-26 2005-09-12 Endovascular Devices Inc Aparato y metodo para administrar mitomicina a traves de un dispositivo medico implantable biocompatible de elucion.
US7416787B2 (en) * 2003-03-31 2008-08-26 Koninklijke Philips Electronics N.V. Medical equipment provided with a coating
US20040236399A1 (en) * 2003-04-22 2004-11-25 Medtronic Vascular, Inc. Stent with improved surface adhesion
US7067169B2 (en) * 2003-06-04 2006-06-27 Chemat Technology Inc. Coated implants and methods of coating
US20050153077A1 (en) * 2003-12-03 2005-07-14 Anthony Gedeon Method of resisting contaminant build up and oxidation of vehicle surfaces and other surfaces
US7405006B2 (en) * 2003-12-16 2008-07-29 Anthony Alan Gedeon Method of treating surfaces for self-sterilization and microbial growth resistance
US7211108B2 (en) * 2004-01-23 2007-05-01 Icon Medical Corp. Vascular grafts with amphiphilic block copolymer coatings
US9498563B2 (en) * 2004-04-23 2016-11-22 Boston Scientific Scimed, Inc. Medical articles having therapeutic-agent-containing regions formed from coalesced polymer particles
US20060083861A1 (en) * 2004-04-24 2006-04-20 Gedeon Anthony A Method of reducing loss in power transmission systems, electrical systems and electronics
US7758892B1 (en) * 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US8999364B2 (en) 2004-06-15 2015-04-07 Nanyang Technological University Implantable article, method of forming same and method for reducing thrombogenicity
US20060025848A1 (en) * 2004-07-29 2006-02-02 Jan Weber Medical device having a coating layer with structural elements therein and method of making the same
US8980300B2 (en) 2004-08-05 2015-03-17 Advanced Cardiovascular Systems, Inc. Plasticizers for coating compositions
US20060029640A1 (en) * 2004-08-05 2006-02-09 Gilbert Jeremy L Medical devices with surface modification for regulating cell growth on or near the surface
WO2006036681A2 (en) * 2004-09-22 2006-04-06 Cartilix, Inc. Cartilage filling device
US20060093647A1 (en) * 2004-10-29 2006-05-04 Villafana Manuel A Multiple layer coating composition
US20060095122A1 (en) * 2004-10-29 2006-05-04 Advanced Cardiovascular Systems, Inc. Implantable devices comprising biologically absorbable star polymers and methods for fabricating the same
US20060127443A1 (en) * 2004-12-09 2006-06-15 Helmus Michael N Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery
US9101500B2 (en) * 2005-01-10 2015-08-11 Trireme Medical, Inc. Stent with self-deployable portion having wings of different lengths
ATE508714T1 (de) * 2005-01-10 2011-05-15 Trireme Medical Inc Stent mit selbstexpandierbarem bereich
US20060216327A1 (en) * 2005-03-28 2006-09-28 Bacterin, Inc. Multilayer coating for releasing biologically-active agents and method of making
US8778375B2 (en) * 2005-04-29 2014-07-15 Advanced Cardiovascular Systems, Inc. Amorphous poly(D,L-lactide) coating
US20070009564A1 (en) * 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
JP4473185B2 (ja) * 2005-07-01 2010-06-02 本田技研工業株式会社 化成処理方法、化成処理剤、及び化成処理部材
US20070038176A1 (en) * 2005-07-05 2007-02-15 Jan Weber Medical devices with machined layers for controlled communications with underlying regions
AU2006270221B2 (en) 2005-07-15 2012-01-19 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
US20070020312A1 (en) * 2005-07-20 2007-01-25 Desnoyer Jessica R Method of fabricating a bioactive agent-releasing implantable medical device
DE602006015235D1 (de) * 2005-08-25 2010-08-12 Medtronic Vascular Inc Polymere zusammensetzungen auf 4-azacaprolactonbasis, die sich für die herstellung von biologisch abbaubaren medizinischen geräten und als beschichtungen für medizinische geräte eignen
US9278161B2 (en) * 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
EP1945144A4 (de) * 2005-10-19 2012-12-05 Kenton W Gregory Verfahren zur verwendung und herstellung von tropoelastin und tropoelastin-biomaterialien
KR101369388B1 (ko) 2005-11-14 2014-03-06 바이오메트 쓰리아이 엘엘씨 임플란트 표면상에 이산 나노입자의 증착방법
US20070196423A1 (en) * 2005-11-21 2007-08-23 Med Institute, Inc. Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent
US8840660B2 (en) * 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US20070173925A1 (en) * 2006-01-25 2007-07-26 Cornova, Inc. Flexible expandable stent
US8089029B2 (en) * 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070185562A1 (en) * 2006-02-08 2007-08-09 Jgf Company Medical device for unstable and vulnerable plaque
US20070224244A1 (en) * 2006-03-22 2007-09-27 Jan Weber Corrosion resistant coatings for biodegradable metallic implants
US20070224235A1 (en) * 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) * 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8048150B2 (en) * 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
EP2019657B1 (de) 2006-04-26 2015-05-27 Micell Technologies, Inc. Beschichtungen mit mehreren wirkstoffen
US20070264303A1 (en) * 2006-05-12 2007-11-15 Liliana Atanasoska Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
EP2032091A2 (de) * 2006-06-29 2009-03-11 Boston Scientific Limited Medizinprodukte mit selektiver beschichtung
US7846361B2 (en) 2006-07-20 2010-12-07 Orbusneich Medical, Inc. Bioabsorbable polymeric composition for a medical device
JP2009545407A (ja) 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド，インコーポレイテッド 三次元分解制御を備えたエンドプロテーゼ
US8952123B1 (en) * 2006-08-02 2015-02-10 Abbott Cardiovascular Systems Inc. Dioxanone-based copolymers for implantable devices
US8092821B2 (en) * 2006-08-25 2012-01-10 Boston Scientific Scimed, Inc. Medical devices having polymeric regions with improved adhesion
US20080177371A1 (en) * 2006-08-28 2008-07-24 Cornova, Inc. Implantable devices and methods of forming the same
ATE508708T1 (de) 2006-09-14 2011-05-15 Boston Scient Ltd Medizinprodukte mit wirkstofffreisetzender beschichtung
US8808726B2 (en) * 2006-09-15 2014-08-19 Boston Scientific Scimed. Inc. Bioerodible endoprostheses and methods of making the same
ATE517590T1 (de) 2006-09-15 2011-08-15 Boston Scient Ltd Biologisch erodierbare endoprothesen
JP2010503485A (ja) * 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 医療用デバイスおよび同デバイスの製造方法
ES2368125T3 (es) * 2006-09-15 2011-11-14 Boston Scientific Scimed, Inc. Endoprótesis bioerosionable con capas inorgánicas bioestables.
US8002821B2 (en) * 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
JP2010503463A (ja) * 2006-09-18 2010-02-04 ボストン サイエンティフィック リミテッド 医療機器の生分解の制御
EP2084310A1 (de) * 2006-10-05 2009-08-05 Boston Scientific Limited Durch plasmaelektrolytische abscheidung gebildete polymerfreie überzüge für medizinische vorrichtungen
CN101631513B (zh) 2006-10-20 2013-06-05 奥巴斯尼茨医学公司 可生物吸收的聚合物组合物和医疗设备
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
US9539593B2 (en) * 2006-10-23 2017-01-10 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
EP2079396A2 (de) * 2006-10-30 2009-07-22 Poly-Med, Inc. Nahtspezifische überzüge zur modulierten freisetzung von biologisch wirksamen mitteln
US7981150B2 (en) * 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US7939095B2 (en) 2006-12-21 2011-05-10 Cordis Corporation Crosslinked silane coating for medical devices
ATE488259T1 (de) 2006-12-28 2010-12-15 Boston Scient Ltd Bioerodierbare endoprothesen und herstellungsverfahren dafür
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
EP2111184B1 (de) * 2007-01-08 2018-07-25 Micell Technologies, Inc. Stents mit biologisch abbaubaren schichten
US8221496B2 (en) 2007-02-01 2012-07-17 Cordis Corporation Antithrombotic and anti-restenotic drug eluting stent
CA2678319A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of coronary microvascular diseases
US20090111826A1 (en) * 2007-02-13 2009-04-30 Louis Lange Use of ranolazine for the treatment of cardiovascular diseases
CA2677931A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of cardiovascular diseases
CA2678325A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of non-coronary microvascular diseases
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
JP5461202B2 (ja) * 2007-03-09 2014-04-02 アイコン メディカル コーポレーション 医療用具用生体吸収性コーティング
WO2008116083A1 (en) * 2007-03-22 2008-09-25 Cv Therapeutics, Inc. Use of ranolazine for elevated brain-type natriuretic peptide
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
JP5443336B2 (ja) * 2007-04-17 2014-03-19 ミセル テクノロジーズ、インコーポレイテッド 生分解性層を有するステント
US7976915B2 (en) * 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US8084077B2 (en) 2007-05-25 2011-12-27 Abbott Laboratories One-step phosphorylcholine-linked polymer coating and drug loading of stent
CA2688314C (en) 2007-05-25 2013-12-03 Micell Technologies, Inc. Polymer films for medical device coating
US20080299195A1 (en) * 2007-05-31 2008-12-04 Brent Blackburn Use of ranolazine for elevated brain-type natriuretic peptide
US8293260B2 (en) * 2007-06-05 2012-10-23 Abbott Cardiovascular Systems Inc. Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices
US8263104B2 (en) * 2007-06-08 2012-09-11 Northwestern University Polymer nanofilm coatings
US8133553B2 (en) 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
KR101023164B1 (ko) * 2007-06-19 2011-03-18 (주)바이오니아 화학물질로 코팅된 금도금 스텐트, 올리고뉴클레오타이드를 바인딩시킨 금도금 스텐트 및 이들의제조방법
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
US20090004243A1 (en) 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8002823B2 (en) * 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
EP2187988B1 (de) 2007-07-19 2013-08-21 Boston Scientific Limited Endoprothese mit nicht verschmutzender oberfläche
US8815273B2 (en) * 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
WO2009018340A2 (en) * 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
WO2009020520A1 (en) * 2007-08-03 2009-02-12 Boston Scientific Scimed, Inc. Coating for medical device having increased surface area
EP2258414A3 (de) 2007-09-04 2014-08-27 Japan Stent Technology Co., Ltd. Stent zur stetigen Arzneimittelabgabe
US8052745B2 (en) * 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
EP2191853B1 (de) 2007-09-28 2015-07-29 Terumo Kabushiki Kaisha In-vivo-dauerimplantationsmaterial
US8608049B2 (en) 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
EP2222893B1 (de) * 2007-10-19 2017-01-04 Biointraface, Inc. Beschichtungsverfahren
WO2009051780A1 (en) * 2007-10-19 2009-04-23 Micell Technologies, Inc. Drug coated stents
US8661630B2 (en) * 2008-05-21 2014-03-04 Abbott Cardiovascular Systems Inc. Coating comprising an amorphous primer layer and a semi-crystalline reservoir layer
US20090110713A1 (en) * 2007-10-31 2009-04-30 Florencia Lim Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices
US20090287302A1 (en) * 2008-05-16 2009-11-19 Chameleon Scientific Corporation Polymer coated spinulose metal surfaces
US20100298925A1 (en) * 2007-10-31 2010-11-25 Chameleon Scientific Corporation Spinulose metal surfaces
US8158216B2 (en) * 2007-10-31 2012-04-17 Metascape Llc Spinulose titanium nanoparticulate surfaces
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8029554B2 (en) * 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US20090118809A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Endoprosthesis with porous reservoir and non-polymer diffusion layer
US20090118813A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Nano-patterned implant surfaces
US20090143855A1 (en) * 2007-11-29 2009-06-04 Boston Scientific Scimed, Inc. Medical Device Including Drug-Loaded Fibers
US8192479B2 (en) 2007-11-30 2012-06-05 Cook Medical Technologies Llc Method and device for vascular therapy
US20100008970A1 (en) * 2007-12-14 2010-01-14 Boston Scientific Scimed, Inc. Drug-Eluting Endoprosthesis
BRPI0906702A2 (pt) * 2008-01-09 2015-06-30 Innovative Health Technologies Llc Grânulos de implante e métodos para realizar a regeneração e preservação óssea
US20090192583A1 (en) * 2008-01-28 2009-07-30 Medtronic Vascular, Inc. Ordered Coatings for Drug Eluting Stents and Medical Devices
ES2545781T3 (es) 2008-01-28 2015-09-15 Biomet 3I, Llc Implante superficial con mayor hidrofilia
CN101932289B (zh) * 2008-01-31 2014-02-19 兴和株式会社 医疗工具的制造方法
US9603980B2 (en) * 2008-02-26 2017-03-28 CARDINAL HEALTH SWITZERLAND 515 GmbH Layer-by-layer stereocomplexed polymers as drug depot carriers or coatings in medical devices
MX350637B (es) * 2008-04-17 2017-09-11 Micell Technologies Inc Stents que tienen capas bioabsorbibles.
US8920491B2 (en) 2008-04-22 2014-12-30 Boston Scientific Scimed, Inc. Medical devices having a coating of inorganic material
US8932346B2 (en) 2008-04-24 2015-01-13 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) * 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8697113B2 (en) 2008-05-21 2014-04-15 Abbott Cardiovascular Systems Inc. Coating comprising a terpolymer comprising caprolactone and glycolide
US20100040672A1 (en) * 2008-06-09 2010-02-18 Northwestern University Delivery of therapeutics
US10799593B2 (en) 2008-06-09 2020-10-13 Northwestern University Nanodiamond particle complexes
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
IL192262A (en) 2008-06-17 2016-05-31 Z H T Eng Equipment And Tech Ltd A polymer that releases drugs into the animal body, a medicinal product containing it and a method for its preparation
EP2303350A2 (de) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprothesen-beschichtung
US8206635B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US8206636B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US10898620B2 (en) 2008-06-20 2021-01-26 Razmodics Llc Composite stent having multi-axial flexibility and method of manufacture thereof
US20100004733A1 (en) * 2008-07-02 2010-01-07 Boston Scientific Scimed, Inc. Implants Including Fractal Structures
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
WO2010009335A1 (en) 2008-07-17 2010-01-21 Micell Technologies, Inc. Drug delivery medical device
US7985252B2 (en) * 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8642063B2 (en) * 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
EP2711031A3 (de) * 2008-09-22 2014-07-02 Boston Scientific Neuromodulation Corporation Implantierbare oder einführbare medizinische Vorrichtungen
US8500687B2 (en) 2008-09-25 2013-08-06 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
US8382824B2 (en) * 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
GB0819296D0 (en) * 2008-10-21 2008-11-26 Smith & Nephew Coating II
US8231980B2 (en) * 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
US8834913B2 (en) * 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
US20100203100A1 (en) * 2009-02-02 2010-08-12 Medtronic, Inc. Antimicrobial accessory for an implantable medical device
US8222360B2 (en) 2009-02-13 2012-07-17 Visiogen, Inc. Copolymers for intraocular lens systems
WO2010101072A1 (ja) * 2009-03-02 2010-09-10 株式会社日本ステントテクノロジー 薬剤溶出性ステント
EP2403546A2 (de) * 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Selbstpufferende medizinische implantate
US8071156B2 (en) * 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
EP2410954A4 (de) * 2009-03-23 2014-03-05 Micell Technologies Inc Periphere stents mit schichten
CN102481195B (zh) * 2009-04-01 2015-03-25 米歇尔技术公司 涂覆支架
CA2759015C (en) 2009-04-17 2017-06-20 James B. Mcclain Stents having controlled elution
US20100273696A1 (en) * 2009-04-23 2010-10-28 Herbert Hopfstock Composition and method for the prevention and removal of unwanted paint on a surface
US20100274352A1 (en) * 2009-04-24 2010-10-28 Boston Scientific Scrimed, Inc. Endoprosthesis with Selective Drug Coatings
US8287937B2 (en) * 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US8858983B2 (en) 2009-04-30 2014-10-14 Medtronic, Inc. Antioxidants and antimicrobial accessories including antioxidants
US8697110B2 (en) 2009-05-14 2014-04-15 Abbott Cardiovascular Systems Inc. Polymers comprising amorphous terpolymers and semicrystalline blocks
US9265633B2 (en) 2009-05-20 2016-02-23 480 Biomedical, Inc. Drug-eluting medical implants
US8992601B2 (en) 2009-05-20 2015-03-31 480 Biomedical, Inc. Medical implants
US9309347B2 (en) 2009-05-20 2016-04-12 Biomedical, Inc. Bioresorbable thermoset polyester/urethane elastomers
US8888840B2 (en) * 2009-05-20 2014-11-18 Boston Scientific Scimed, Inc. Drug eluting medical implant
US20110319987A1 (en) * 2009-05-20 2011-12-29 Arsenal Medical Medical implant
AU2010249558A1 (en) * 2009-05-20 2011-12-08 Arsenal Medical, Inc. Medical implant
US9388275B2 (en) * 2009-06-01 2016-07-12 International Business Machines Corporation Method of ring-opening polymerization, and related compositions and articles
CN102596274B (zh) * 2009-07-14 2015-11-25 港大科桥有限公司 聚合物基和表面处理的金属杂化材料及其制作方法
US8119704B2 (en) * 2009-07-21 2012-02-21 Abbott Cardiovascular Systems Inc. Implantable medical device comprising copolymer of L-lactide with improved fracture toughness
US20110022158A1 (en) * 2009-07-22 2011-01-27 Boston Scientific Scimed, Inc. Bioerodible Medical Implants
ES2387115B1 (es) * 2009-09-24 2013-07-03 Universitat Politècnica De Catalunya Nuevos polimeros proteicos recombinantes y metodo de bioactivacion de superficies con dichos polimeros
KR101107223B1 (ko) * 2009-11-10 2012-01-25 한국과학기술연구원 금속 기판에 대한 고분자의 코팅 접착력을 향상시키기 위한 나노 커플링
EP2338534A2 (de) * 2009-12-21 2011-06-29 Biotronik VI Patent AG Medizinisches Implantat, Beschichtungsverfahren sowie Implantationsverfahren
WO2011097103A1 (en) * 2010-02-02 2011-08-11 Micell Technologies, Inc. Stent and stent delivery system with improved deliverability
US8668732B2 (en) * 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
WO2011133655A1 (en) 2010-04-22 2011-10-27 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
EP2566535A4 (de) * 2010-05-03 2013-12-18 Izhar Halahmi Abgabevorrichtung zur verabreichung eines bioaktiven wirkstoffs
US20110311601A1 (en) * 2010-06-22 2011-12-22 Michael Kleine Antimicrobial medical devices
US20130172853A1 (en) 2010-07-16 2013-07-04 Micell Technologies, Inc. Drug delivery medical device
CN102008751B (zh) * 2010-11-24 2014-01-08 北京道淼浩博科技发展有限公司 一种生物降解支架复合材料及其制备方法
US20120158123A1 (en) * 2010-12-15 2012-06-21 Biotronik Ag Polymer stent
US8911427B2 (en) 2010-12-28 2014-12-16 Medtronic, Inc. Therapeutic agent reservoir delivery system
KR101770827B1 (ko) * 2011-03-10 2017-08-23 서울대학교산학협력단 혈관내피 전구세포를 선택적으로 포획할 수 있는 스텐트 및 이의 제조 방법
WO2012166819A1 (en) 2011-05-31 2012-12-06 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
CN103045161B (zh) * 2011-10-11 2016-03-30 北京格加纳米技术有限公司 一种有机物表面修饰的金属和金属氧化物材料及其制造方法
CA2841360A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
WO2013123509A1 (en) * 2012-02-17 2013-08-22 Bacterin International, Inc. Adjustable bioactive agent dispersion within a polymeric coating
US9131995B2 (en) 2012-03-20 2015-09-15 Biomet 3I, Llc Surface treatment for an implant surface
CN102772831A (zh) * 2012-08-20 2012-11-14 道淼科技(北京)有限公司 一种可降解载药支架
JP6247216B2 (ja) 2012-09-10 2017-12-13 住友ゴム工業株式会社 表面改質方法及び表面改質弾性体
CN103785066B (zh) * 2012-11-01 2015-04-15 中国科学院上海硅酸盐研究所 I型胶原改性的多孔钛涂层及其制备方法
JP5620456B2 (ja) 2012-11-20 2014-11-05 住友ゴム工業株式会社 表面改質方法及び表面改質弾性体
JP6053482B2 (ja) 2012-11-30 2016-12-27 住友ゴム工業株式会社 注射器用ガスケットの製造方法
CN110269959A (zh) 2013-03-12 2019-09-24 脉胜医疗技术公司 可生物吸收的生物医学植入物
JP5816222B2 (ja) 2013-04-25 2015-11-18 住友ゴム工業株式会社 表面改質方法及び表面改質弾性体
US10272606B2 (en) 2013-05-15 2019-04-30 Micell Technologies, Inc. Bioabsorbable biomedical implants
JP5797239B2 (ja) 2013-06-11 2015-10-21 住友ゴム工業株式会社 立体形状物の表面改質方法及び注射器用ガスケット
EP3000842B1 (de) 2013-06-20 2019-11-06 Sumitomo Rubber Industries, Ltd. Oberflächenmodifizierungsverfahren und oberflächenmodifizierungskörper
JP5820489B2 (ja) 2014-01-06 2015-11-24 住友ゴム工業株式会社 表面改質方法及び表面改質弾性体
US11292924B2 (en) * 2014-04-08 2022-04-05 Silcotek Corp. Thermal chemical vapor deposition coated article and process
JP6371165B2 (ja) * 2014-09-02 2018-08-08 住友ゴム工業株式会社 金属医療用具
JP6338504B2 (ja) 2014-10-02 2018-06-06 住友ゴム工業株式会社 表面改質方法及び表面改質弾性体
US11241322B2 (en) * 2014-10-28 2022-02-08 Jimro Co., Ltd. Drug-eluting stent
WO2016196633A1 (en) * 2015-06-01 2016-12-08 William Marsh Rice University Surface coating method to improve implantable device biocompatibility
JP6613692B2 (ja) 2015-08-03 2019-12-04 住友ゴム工業株式会社 表面改質方法及び表面改質弾性体
JP6551022B2 (ja) 2015-08-03 2019-07-31 住友ゴム工業株式会社 表面改質方法及び表面改質体
US10668259B2 (en) 2015-10-21 2020-06-02 Materials Science Associates, LLC Metal oxide and polymer controlled delivery systems, sunscreens, treatments, and topical coating applicators
CN110446521B (zh) * 2017-01-21 2022-05-06 生物克瑞德公司 配置用于一氧化氮的控制释放的医疗产品和方法
EP3579912B1 (de) * 2017-02-09 2022-08-31 MED-EL Elektromedizinische Geraete GmbH Dexamethasonbeschichtung zur verwendung mit elektrodenträgern
JP7011237B2 (ja) 2017-05-12 2022-01-26 住友ゴム工業株式会社 ポリマー含浸基材樹脂の製造方法
CN110438455A (zh) * 2018-05-02 2019-11-12 南京理工大学 聚乳酸基环丙沙星抗菌薄膜的制备方法
WO2021041505A1 (en) * 2019-08-26 2021-03-04 Forman, Mervyn B. Medical devices for continuous delivery of therapeutic agents
KR102407468B1 (ko) * 2021-11-30 2022-06-10 주식회사 파인트코리아 스텐트 제조용 생분해성 복합소재 조성물 및 이의 제조 방법

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104296A (en) * 1970-09-28 1978-08-01 Union Carbide Corporation Organofunctional silicon compounds
DE2746006A1 (de) * 1977-10-13 1979-04-19 Veba Chemie Ag Verfahren zum beschichten von glasoberflaechen
US4215165A (en) * 1978-07-17 1980-07-29 Chemische Werke Huls Aktiengesellschaft Method for coating of glass surfaces
US4591652A (en) * 1985-04-12 1986-05-27 Scm Corporation Polyhydroxyl silanes or siloxanes
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US5527337A (en) 1987-06-25 1996-06-18 Duke University Bioabsorbable stent and method of making the same
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
US4916193A (en) 1987-12-17 1990-04-10 Allied-Signal Inc. Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
DE68920476T2 (de) * 1988-05-17 1995-06-01 Dow Corning Ltd Organosiliziumverbindungen.
US5262451A (en) 1988-06-08 1993-11-16 Cardiopulmonics, Inc. Multifunctional thrombo-resistant coatings and methods of manufacture
US5053048A (en) 1988-09-22 1991-10-01 Cordis Corporation Thromboresistant coating
US4994071A (en) 1989-05-22 1991-02-19 Cordis Corporation Bifurcating stent apparatus and method
US5304121A (en) 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
US5545208A (en) 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
EP0484057A3 (en) 1990-11-02 1993-04-21 The Dow Chemical Company Antithrombogenic surfaces, their preparation, and materials therefore
US5221698A (en) 1991-06-27 1993-06-22 The Regents Of The University Of Michigan Bioactive composition
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
IL112873A (en) * 1994-03-08 2005-03-20 Wyeth Corp Rapamycin-fkbp12 binding proteins, their isolation and their use
EP0755272B1 (de) * 1994-04-15 2001-07-11 Cobe Cardiovascular, Inc. Blutverträglicher beschichteter artikel
US5649977A (en) 1994-09-22 1997-07-22 Advanced Cardiovascular Systems, Inc. Metal reinforced polymer stent
CA2135846A1 (en) * 1994-11-15 1996-05-16 Alexander Henderson Cross-linkable polymer composition containing a lactone moiety as a catalyst
US5637113A (en) 1994-12-13 1997-06-10 Advanced Cardiovascular Systems, Inc. Polymer film for wrapping a stent structure
US6017577A (en) 1995-02-01 2000-01-25 Schneider (Usa) Inc. Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices
US5820917A (en) 1995-06-07 1998-10-13 Medtronic, Inc. Blood-contacting medical device and method
US5866702A (en) 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2
US6013855A (en) * 1996-08-06 2000-01-11 United States Surgical Grafting of biocompatible hydrophilic polymers onto inorganic and metal surfaces
AUPO251096A0 (en) * 1996-09-23 1996-10-17 Cardiac Crc Nominees Pty Limited Polysiloxane-containing polyurethane elastomeric compositions
DE19640364A1 (de) * 1996-09-30 1998-04-02 Basf Ag Topische Mittel zur Prophylaxe oder Behandlung bakterieller Hautinfektionen
US5786022A (en) 1996-10-31 1998-07-28 Ethicon, Inc. Coating mixture for surgical articles
US5980551A (en) * 1997-02-07 1999-11-09 Endovasc Ltd., Inc. Composition and method for making a biodegradable drug delivery stent
US5977204A (en) * 1997-04-11 1999-11-02 Osteobiologics, Inc. Biodegradable implant material comprising bioactive ceramic
US6211249B1 (en) 1997-07-11 2001-04-03 Life Medical Sciences, Inc. Polyester polyether block copolymers
CA2298543A1 (en) 1997-08-13 1999-02-25 James Barry Loading and release of water-insoluble drugs
US6485514B1 (en) 1997-12-12 2002-11-26 Supergen, Inc. Local delivery of therapeutic agents
US6335340B1 (en) 1997-12-19 2002-01-01 Smithkline Beecham Corporation compounds of heteroaryl substituted imidazole, their pharmaceutical compositons and uses
ATE219693T1 (de) 1998-04-27 2002-07-15 Surmodics Inc Bioaktive wirkstoffe freisetzende beschichtungen
US6001945A (en) * 1998-07-15 1999-12-14 Dow Corning Corporation Hyperbranched polymers containing silicon atoms
US5997954A (en) * 1998-07-15 1999-12-07 Dow Corning Corporation Method of rendering substrates water repellent using hyperbranched polymers containing silicon atoms
US6248127B1 (en) 1998-08-21 2001-06-19 Medtronic Ave, Inc. Thromboresistant coated medical device
US6335029B1 (en) * 1998-08-28 2002-01-01 Scimed Life Systems, Inc. Polymeric coatings for controlled delivery of active agents
US6342591B1 (en) * 1998-09-22 2002-01-29 Biosurface Engineering Technologies, Inc. Amphipathic coating for modulating cellular adhesion composition and methods
US6187024B1 (en) * 1998-11-10 2001-02-13 Target Therapeutics, Inc. Bioactive coating for vaso-occlusive devices
US6120847A (en) 1999-01-08 2000-09-19 Scimed Life Systems, Inc. Surface treatment method for stent coating
WO2000044580A1 (en) 1999-01-27 2000-08-03 Compumedics Sleep Pty. Ltd. Vigilance monitoring system
TR200102714T2 (tr) 1999-02-01 2002-01-21 Cv Therapeutics, Inc. Sikline bağımlı kinaz 2 ve IkB-&'nın pürün inhibitörleri
US6403567B1 (en) 1999-06-22 2002-06-11 Cv Therapeutics, Inc. N-pyrazole A2A adenosine receptor agonists
US6214807B1 (en) 1999-06-22 2001-04-10 Cv Therapeutics, Inc. C-pyrazole 2A A receptor agonists
US6521431B1 (en) * 1999-06-22 2003-02-18 Access Pharmaceuticals, Inc. Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments
US6180615B1 (en) 1999-06-22 2001-01-30 Cv Therapeutics, Inc. Propargyl phenyl ether A2A receptor agonists
ATE252595T1 (de) 1999-06-22 2003-11-15 Cv Therapeutics Inc A2a rezeptor agonisten
US6258121B1 (en) * 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
CA2441733A1 (en) * 2001-03-29 2002-10-10 Vertex Pharmaceuticals Incorporated Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases
US6641611B2 (en) * 2001-11-26 2003-11-04 Swaminathan Jayaraman Therapeutic coating for an intravascular implant
US20030077310A1 (en) * 2001-10-22 2003-04-24 Chandrashekhar Pathak Stent coatings containing HMG-CoA reductase inhibitors

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