ATE478676T1 - Verfahren zur abgabe von fusionspolypeptid in eine zelle - Google Patents

Verfahren zur abgabe von fusionspolypeptid in eine zelle

Info

Publication number
ATE478676T1
ATE478676T1 AT06842388T AT06842388T ATE478676T1 AT E478676 T1 ATE478676 T1 AT E478676T1 AT 06842388 T AT06842388 T AT 06842388T AT 06842388 T AT06842388 T AT 06842388T AT E478676 T1 ATE478676 T1 AT E478676T1
Authority
AT
Austria
Prior art keywords
cell
fusion polypeptide
methods
fusion polypeptides
delivery
Prior art date
Application number
AT06842388T
Other languages
English (en)
Inventor
Sang-Kyou Lee
Seung-Kyou Lee
Je-Min Choi
Original Assignee
Forhumantech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forhumantech Co Ltd filed Critical Forhumantech Co Ltd
Application granted granted Critical
Publication of ATE478676T1 publication Critical patent/ATE478676T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06842388T 2005-11-04 2006-11-03 Verfahren zur abgabe von fusionspolypeptid in eine zelle ATE478676T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73318305P 2005-11-04 2005-11-04
PCT/IB2006/003971 WO2007052172A2 (en) 2005-11-04 2006-11-03 Methods for fusion polypeptide delivery into a cell

Publications (1)

Publication Number Publication Date
ATE478676T1 true ATE478676T1 (de) 2010-09-15

Family

ID=38006264

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06842388T ATE478676T1 (de) 2005-11-04 2006-11-03 Verfahren zur abgabe von fusionspolypeptid in eine zelle

Country Status (8)

Country Link
US (1) US7723299B2 (de)
EP (1) EP1942925B1 (de)
JP (1) JP2010509181A (de)
KR (1) KR20080084937A (de)
CN (1) CN101355957A (de)
AT (1) ATE478676T1 (de)
DE (1) DE602006016468D1 (de)
WO (1) WO2007052172A2 (de)

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EP2044108A4 (de) * 2006-07-24 2010-06-30 Forhumantech Co Ltd Pharmazeutische zusammensetzung zur linderung und behandlung ischämischer leiden sowie verfahren zu ihrer verabreichung
EP2057195A4 (de) * 2006-08-29 2010-05-12 Forhumantech Co Ltd Pharmazeutische zusammensetzung zur unterdrückung von apoptose und verfahren zu ihrer verabreichung
US20090047703A1 (en) * 2007-08-17 2009-02-19 University Of Maryland, Baltimore ERG-1 Peptides and Polynucleotides and Their Use in the Treatment and Diagnosis of Disease
AU2008295509A1 (en) * 2007-08-29 2009-03-12 Tufts University Methods of making and using a cell penetrating peptide for enhanced delivery of nucleic acids, proteins, drugs, and adenovirus to tissues and cells, and compositions and kits
US7981446B2 (en) 2007-11-26 2011-07-19 Forhumantech. Co., Ltd. Pharmaceutical compositions and methods for delivering nucleic acids into cells
EP2253326B1 (de) * 2008-02-28 2018-04-04 Toray Industries, Inc. Pharmazeutische zusammensetzung zur transnasalen verabreichung
JP2010189302A (ja) * 2009-02-17 2010-09-02 Hiroshima Univ 病変間葉系幹細胞が関連する疾患の治療剤および間葉系幹細胞の検出マーカーの利用
US20130079382A1 (en) 2009-10-12 2013-03-28 Larry J. Smith Methods and Compositions for Modulating Gene Expression Using Oligonucleotide Based Drugs Administered in vivo or in vitro
KR101557343B1 (ko) * 2010-12-10 2015-10-06 연세대학교 산학협력단 전사인자 ｇａｔａ-3의 ｄｎａ 결합 도메인과 단백질 운반 도메인을 융합한 단백질을 이용한 알러지성 천식 치료용 약학 조성물 및 이를 이용한 치료방법
CN102349995B (zh) * 2011-10-24 2013-06-05 武汉大学 一种广谱抗病毒的药物及其制备方法和应用
CN105327350A (zh) * 2014-07-23 2016-02-17 中国科学院上海巴斯德研究所 泛素化途径相关因子在调控辅助性t细胞功能中的应用
CN107074910B (zh) * 2014-08-17 2022-02-18 塞里维瑞疗法公司 高级大分子转导域序列、编码其的多核苷酸及其用途
US11351224B2 (en) 2015-08-21 2022-06-07 Iucf-Hyu (Industry-University Cooperation Foundation Hanyang University) Pharmaceutical composition for preventing and treating transplant rejection
WO2017034244A1 (ko) * 2015-08-21 2017-03-02 한양대학교 산학협력단 중추신경계 질환에 대한 예방 또는 치료효과를 갖는 펩타이드 및 이를 유효성분으로 하는 중추신경계 질환 예방 및 치료용 약학적 조성물
CN108137659B (zh) * 2015-08-21 2021-11-26 汉阳大学校产学协力团 具有预防或治疗中枢神经系统疾病作用的肽和包含其作为活性成分的药物组合物
WO2017119521A1 (ko) * 2016-01-06 2017-07-13 이상규 P65의 전사 조절 도메인과 단백질 운반 도메인을 포함하는 신규 융합 단백질 및 이의 용도
KR20180109272A (ko) * 2017-03-27 2018-10-08 한양대학교 산학협력단 세포투과성 펩타이드와 ctCTLA4 펩타이드가 융합된 융합단백질을 유효성분으로 하는 염증성 호흡기 질환 예방 또는 치료용 약학 조성물
CN107365784A (zh) * 2017-08-02 2017-11-21 滨州医学院 一种用于递送至中枢神经系统的融合蛋白及合成方法
KR101939323B1 (ko) * 2017-09-29 2019-01-16 주식회사 바이오셀트란 탈모 방지 및 발모 촉진 효과를 가지는 피부투과성 단백질 및 그의 용도
EP4086275A4 (de) * 2019-12-31 2024-04-17 Xiamen University Multimerisationsabgabesystem zur intrazellulären abgabe von molekülen

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AU4085297A (en) 1996-08-23 1998-03-06 Chiron Corporation Human polyhomeotic 1(hphl) acts as a tumor suppressor
AU741546B2 (en) * 1997-07-24 2001-12-06 Perseptive Biosystems, Inc. Conjugates of transporter peptides and nucleic acid analogs, and their use
US6251599B1 (en) * 1998-11-06 2001-06-26 Selective Genetics, Inc. Stabilized nucleic acid compositions and methods of preparation and use thereof
US6903077B1 (en) * 1999-01-04 2005-06-07 University Of Vermont And State Agricultural College Methods and products for delivering nucleic acids
US20030104622A1 (en) * 1999-09-01 2003-06-05 Robbins Paul D. Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
GB0103110D0 (en) * 2000-08-25 2001-03-28 Aventis Pharma Inc A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1
KR20030062788A (ko) * 2002-01-19 2003-07-28 포휴먼텍(주) 생체분자 전달 펩타이드 ｍｐｈ1-ｂｔｍ 및 이것을포함하는 생명공학제품
KR20030062789A (ko) 2002-01-19 2003-07-28 포휴먼텍(주) 생체분자 전달 펩타이드 ｓｉｍ2-ｂｔｍ 및 이것을포함하는 생명공학제품
KR100591936B1 (ko) 2002-11-12 2006-06-22 포휴먼텍(주) 세포내 ｄｎａ／ｒｎａ 전달 방법, 및 이것의 기초 및임상학적 응용
US7166692B2 (en) 2003-03-04 2007-01-23 Canbrex Bio Science Walkersville, Inc. Intracellular delivery of small molecules, proteins, and nucleic acids
JP4879020B2 (ja) * 2003-05-01 2012-02-15 コーネル リサーチ ファウンデイション インコーポレイテッド 細胞に分子を送達する方法及び担体複合体
US7339042B2 (en) * 2003-06-09 2008-03-04 University Of Florida Research Foundation, Inc. Gene delivery to tumors
JP4550811B2 (ja) * 2003-06-09 2010-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング パピローマウイルスのインヒビター
CN1930304B (zh) * 2003-11-21 2016-01-06 Anp技术公司 不对称支化的聚合物缀合物和微阵列检测
US20060035815A1 (en) * 2004-05-04 2006-02-16 Nastech Pharmaceutical Company Inc. Pharmaceutical compositions for delivery of ribonucleic acid to a cell
EP2057195A4 (de) * 2006-08-29 2010-05-12 Forhumantech Co Ltd Pharmazeutische zusammensetzung zur unterdrückung von apoptose und verfahren zu ihrer verabreichung
US7981446B2 (en) * 2007-11-26 2011-07-19 Forhumantech. Co., Ltd. Pharmaceutical compositions and methods for delivering nucleic acids into cells

Also Published As

Publication number Publication date
CN101355957A (zh) 2009-01-28
DE602006016468D1 (de) 2010-10-07
US20070105775A1 (en) 2007-05-10
US7723299B2 (en) 2010-05-25
JP2010509181A (ja) 2010-03-25
WO2007052172A8 (en) 2008-05-02
EP1942925A2 (de) 2008-07-16
KR20080084937A (ko) 2008-09-22
EP1942925B1 (de) 2010-08-25
WO2007052172A3 (en) 2007-11-29
EP1942925A4 (de) 2009-07-22
WO2007052172A2 (en) 2007-05-10

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