ATE442367T1 - Pyrazolo(3,4-b)pyridinverbindungen und ihre verwendung als phosphodiesterasinhibitoren - Google Patents

Pyrazolo(3,4-b)pyridinverbindungen und ihre verwendung als phosphodiesterasinhibitoren

Info

Publication number
ATE442367T1
ATE442367T1 AT03778283T AT03778283T ATE442367T1 AT E442367 T1 ATE442367 T1 AT E442367T1 AT 03778283 T AT03778283 T AT 03778283T AT 03778283 T AT03778283 T AT 03778283T AT E442367 T1 ATE442367 T1 AT E442367T1
Authority
AT
Austria
Prior art keywords
sub
sup
optionally substituted
formula
inhibitors
Prior art date
Application number
AT03778283T
Other languages
English (en)
Inventor
David Allen
Diane Coe
Caroline Cook
Michael Dowle
Christopher Edlin
Julie Hamblin
Martin Johnson
Paul Jones
Richard Knowles
Mika Lindvall
Charlotte Mitchell
Alison Redgrave
Peter Ward
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0221455A external-priority patent/GB0221455D0/en
Priority claimed from GBGB0230045.7A external-priority patent/GB0230045D0/en
Priority claimed from GB0306595A external-priority patent/GB0306595D0/en
Priority claimed from GB0308017A external-priority patent/GB0308017D0/en
Priority claimed from GB0319708A external-priority patent/GB0319708D0/en
Priority claimed from GB0321074A external-priority patent/GB0321074D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE442367T1 publication Critical patent/ATE442367T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03778283T 2002-09-16 2003-09-12 Pyrazolo(3,4-b)pyridinverbindungen und ihre verwendung als phosphodiesterasinhibitoren ATE442367T1 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0221455A GB0221455D0 (en) 2002-09-16 2002-09-16 Compounds
GBGB0230045.7A GB0230045D0 (en) 2002-12-23 2002-12-23 Compounds
GB0306595A GB0306595D0 (en) 2003-03-21 2003-03-21 Compounds
GB0308017A GB0308017D0 (en) 2003-04-07 2003-04-07 Compounds
GB0319708A GB0319708D0 (en) 2003-08-21 2003-08-21 Compounds
GB0321074A GB0321074D0 (en) 2003-09-09 2003-09-09 Compounds
PCT/EP2003/011814 WO2004024728A2 (en) 2002-09-16 2003-09-12 Pyrazolo[3,4-b]pyridine compounds, and their use as phosphodiesterase inhibitors

Publications (1)

Publication Number Publication Date
ATE442367T1 true ATE442367T1 (de) 2009-09-15

Family

ID=31999797

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03778283T ATE442367T1 (de) 2002-09-16 2003-09-12 Pyrazolo(3,4-b)pyridinverbindungen und ihre verwendung als phosphodiesterasinhibitoren

Country Status (23)

Country Link
US (2) US20060089375A1 (de)
EP (1) EP1539753B1 (de)
JP (1) JP2006503108A (de)
KR (1) KR20050052501A (de)
CN (1) CN100387598C (de)
AT (1) ATE442367T1 (de)
AU (1) AU2010201417A1 (de)
BR (1) BR0314392A (de)
CA (1) CA2497550A1 (de)
CY (1) CY1109619T1 (de)
DE (1) DE60329193D1 (de)
DK (1) DK1539753T3 (de)
ES (1) ES2331119T3 (de)
IL (1) IL166898A (de)
IS (1) IS7709A (de)
MA (1) MA27475A1 (de)
MX (1) MXPA05002887A (de)
NO (1) NO20050841L (de)
NZ (1) NZ538515A (de)
PL (1) PL375993A1 (de)
PT (1) PT1539753E (de)
SI (1) SI1539753T1 (de)
WO (1) WO2004024728A2 (de)

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CY1109619T1 (el) 2014-08-13
JP2006503108A (ja) 2006-01-26
PL375993A1 (en) 2005-12-12
BR0314392A (pt) 2005-07-12
WO2004024728A3 (en) 2004-10-21
EP1539753B1 (de) 2009-09-09
NZ538515A (en) 2007-04-27
PT1539753E (pt) 2009-12-10
CN100387598C (zh) 2008-05-14
DK1539753T3 (da) 2010-01-04
EP1539753A2 (de) 2005-06-15
MXPA05002887A (es) 2005-05-27
KR20050052501A (ko) 2005-06-02
SI1539753T1 (sl) 2009-12-31
DE60329193D1 (de) 2009-10-22
WO2004024728A2 (en) 2004-03-25
ES2331119T3 (es) 2009-12-22
CN1694882A (zh) 2005-11-09
US20060089375A1 (en) 2006-04-27
IL166898A (en) 2010-06-30
MA27475A1 (fr) 2005-08-01
US20080175914A1 (en) 2008-07-24
AU2010201417A1 (en) 2010-04-29
AU2003285300A1 (en) 2004-04-30
CA2497550A1 (en) 2004-03-25
IS7709A (is) 2005-02-24

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