WO2009041591A1 - 縮環ピリジン誘導体 - Google Patents

縮環ピリジン誘導体 Download PDF

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Publication number
WO2009041591A1
WO2009041591A1 PCT/JP2008/067449 JP2008067449W WO2009041591A1 WO 2009041591 A1 WO2009041591 A1 WO 2009041591A1 JP 2008067449 W JP2008067449 W JP 2008067449W WO 2009041591 A1 WO2009041591 A1 WO 2009041591A1
Authority
WO
WIPO (PCT)
Prior art keywords
formula
hydrogen atom
pyridine derivative
different
same
Prior art date
Application number
PCT/JP2008/067449
Other languages
English (en)
French (fr)
Inventor
Daisuke Nakashima
Seiji Aratake
Kimihisa Ueno
Mirai Mizutani
Daisuke Harada
Katsuya Kobayashi
Original Assignee
Kyowa Hakko Kirin Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kirin Co., Ltd. filed Critical Kyowa Hakko Kirin Co., Ltd.
Publication of WO2009041591A1 publication Critical patent/WO2009041591A1/ja

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

式（I） ｛式中、R1はハロゲンを表し、 R2はNR4R5（式中、R4及びR5は、同一または異なって、水素原子、置換基を有していてもよいアラルキル等を表す）等を表し、 R3は式(A) ［式中、R8及びR9は同一または異なって、水素原子、置換基を有していてもよいアリール等を表し、Z2は窒素原子またはCR14（式中、R14は水素原子等を表す）を表し、Lは単結合等を表し、k及びmはそれぞれ0から2の整数を表し、nは0から4の整数を表す］等を表し、 式(B)は式(C) （式中、R16及びR17は、同一または異なって、水素原子等を表し、Z1は硫黄原子等を表す）等を表す｝で表される縮環ピリジン誘導体またはその薬理学的に許容される塩等を提供する。
PCT/JP2008/067449 2007-09-28 2008-09-26 縮環ピリジン誘導体 WO2009041591A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-252805 2007-09-28
JP2007252805 2007-09-28

Publications (1)

Publication Number Publication Date
WO2009041591A1 true WO2009041591A1 (ja) 2009-04-02

Family

ID=40511471

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/067449 WO2009041591A1 (ja) 2007-09-28 2008-09-26 縮環ピリジン誘導体

Country Status (1)

Country Link
WO (1) WO2009041591A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8324239B2 (en) 2010-04-21 2012-12-04 Novartis Ag Furopyridine compounds and uses thereof
WO2015182734A1 (ja) * 2014-05-30 2015-12-03 協和発酵キリン株式会社 含窒素複素環化合物

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005113560A2 (en) * 2004-05-14 2005-12-01 Wyeth THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AS PROTEIN KINASE INHIBITORS
JP2006503108A (ja) * 2002-09-16 2006-01-26 グラクソ　グループ　リミテッド ピラゾロ［３，４−ｂ］ピリジン化合物およびそれのホスホジエステラーゼ阻害薬としての使用
JP2006505552A (ja) * 2002-10-09 2006-02-16 サイオス インク． ｐ３８キナーゼ阻害剤としてのアザインドール系誘導体
WO2006061642A1 (en) * 2004-12-09 2006-06-15 Xention Discovery Limited Compounds
WO2007015866A2 (en) * 2005-07-20 2007-02-08 Kalypsys, Inc. Inhibitors of p38 kinase and methods of treating inflammatory disorders
WO2008108309A1 (ja) * 2007-03-02 2008-09-12 Kyowa Hakko Kirin Co., Ltd. 縮環ピリジン誘導体

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006503108A (ja) * 2002-09-16 2006-01-26 グラクソ　グループ　リミテッド ピラゾロ［３，４−ｂ］ピリジン化合物およびそれのホスホジエステラーゼ阻害薬としての使用
JP2006505552A (ja) * 2002-10-09 2006-02-16 サイオス インク． ｐ３８キナーゼ阻害剤としてのアザインドール系誘導体
WO2005113560A2 (en) * 2004-05-14 2005-12-01 Wyeth THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AS PROTEIN KINASE INHIBITORS
WO2006061642A1 (en) * 2004-12-09 2006-06-15 Xention Discovery Limited Compounds
WO2007015866A2 (en) * 2005-07-20 2007-02-08 Kalypsys, Inc. Inhibitors of p38 kinase and methods of treating inflammatory disorders
WO2008108309A1 (ja) * 2007-03-02 2008-09-12 Kyowa Hakko Kirin Co., Ltd. 縮環ピリジン誘導体

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8324239B2 (en) 2010-04-21 2012-12-04 Novartis Ag Furopyridine compounds and uses thereof
WO2015182734A1 (ja) * 2014-05-30 2015-12-03 協和発酵キリン株式会社 含窒素複素環化合物

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