ATE434625T1 - Verfahren zur schmerzbehandlung durch verabreichung eines antagonistischen antikörpers gegen den nervenwachstumfaktor und eines opioid- analgetikums sowie diese enthaltende zusammensetzungen - Google Patents
Verfahren zur schmerzbehandlung durch verabreichung eines antagonistischen antikörpers gegen den nervenwachstumfaktor und eines opioid- analgetikums sowie diese enthaltende zusammensetzungenInfo
- Publication number
- ATE434625T1 ATE434625T1 AT03816571T AT03816571T ATE434625T1 AT E434625 T1 ATE434625 T1 AT E434625T1 AT 03816571 T AT03816571 T AT 03816571T AT 03816571 T AT03816571 T AT 03816571T AT E434625 T1 ATE434625 T1 AT E434625T1
- Authority
- AT
- Austria
- Prior art keywords
- growth factor
- antibody against
- nerve growth
- opioid analgesic
- antagonist antibody
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41734702P | 2002-10-08 | 2002-10-08 | |
PCT/US2003/032113 WO2004096122A2 (en) | 2002-10-08 | 2003-10-08 | Use of ngf antagonists and opioids for treating pain |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE434625T1 true ATE434625T1 (de) | 2009-07-15 |
Family
ID=33415832
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03816571T ATE434625T1 (de) | 2002-10-08 | 2003-10-08 | Verfahren zur schmerzbehandlung durch verabreichung eines antagonistischen antikörpers gegen den nervenwachstumfaktor und eines opioid- analgetikums sowie diese enthaltende zusammensetzungen |
Country Status (18)
Country | Link |
---|---|
US (1) | US20040131615A1 (de) |
EP (2) | EP2100902B1 (de) |
JP (1) | JP2006517524A (de) |
KR (1) | KR20050067174A (de) |
CN (1) | CN1878794B (de) |
AT (1) | ATE434625T1 (de) |
AU (1) | AU2003304060A1 (de) |
BR (1) | BR0315167A (de) |
CA (1) | CA2501694A1 (de) |
DE (1) | DE60328128D1 (de) |
ES (2) | ES2326881T3 (de) |
MX (1) | MXPA05003501A (de) |
NO (1) | NO20052221L (de) |
PL (1) | PL379989A1 (de) |
RU (1) | RU2005113996A (de) |
UA (1) | UA80447C2 (de) |
WO (1) | WO2004096122A2 (de) |
ZA (1) | ZA200502611B (de) |
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EP1575517B1 (de) | 2002-12-24 | 2012-04-11 | Rinat Neuroscience Corp. | Anti-ngf-antikörper und verfahren zu ihrer verwendung |
US9498530B2 (en) | 2002-12-24 | 2016-11-22 | Rinat Neuroscience Corp. | Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same |
AU2011201157C1 (en) * | 2002-12-24 | 2017-09-07 | Rinat Neuroscience Corp. | Anti-NGF antibodies and methods using same |
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AU2005243247B2 (en) | 2004-04-07 | 2012-03-01 | Regents Of The University Of Minnesota | Methods for treating bone cancer pain by administering a nerve growth factor antagonist |
ITRM20050290A1 (it) * | 2005-06-07 | 2006-12-08 | Lay Line Genomics Spa | Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. |
ITRM20050332A1 (it) * | 2005-06-24 | 2006-12-25 | Lay Line Genomics Spa | Uso di molecole in grado di bloccare l'attivita' di trka per potenziare gli effetti di analgesici oppiacei sul dolore. |
CA2623648C (en) | 2005-09-21 | 2018-05-22 | The Regents Of The University Of California | Systems, compositions, and methods for local imaging and treatment of pain |
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RU2473564C2 (ru) | 2007-08-10 | 2013-01-27 | Ридженерон Фармасьютикалз, Инк. | Антитела человека с высокой аффинностью к фактору роста нервов человека |
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US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
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US9855332B2 (en) | 2011-05-20 | 2018-01-02 | Alderbio Holdings Llc | Use of anti-CGRP antibodies and antibody fragments to treat diarrhea in subjects with diseases or treatments that result in elevated CGRP levels |
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2003
- 2003-08-10 UA UAA200504332A patent/UA80447C2/uk unknown
- 2003-10-08 RU RU2005113996/14A patent/RU2005113996A/ru not_active Application Discontinuation
- 2003-10-08 CN CN2003801053379A patent/CN1878794B/zh not_active Expired - Lifetime
- 2003-10-08 KR KR1020057006105A patent/KR20050067174A/ko not_active Application Discontinuation
- 2003-10-08 US US10/682,332 patent/US20040131615A1/en not_active Abandoned
- 2003-10-08 BR BR0315167-0A patent/BR0315167A/pt not_active IP Right Cessation
- 2003-10-08 EP EP09163527.6A patent/EP2100902B1/de not_active Expired - Lifetime
- 2003-10-08 EP EP03816571A patent/EP1575522B1/de not_active Revoked
- 2003-10-08 ES ES03816571T patent/ES2326881T3/es not_active Expired - Lifetime
- 2003-10-08 ES ES09163527T patent/ES2767744T3/es not_active Expired - Lifetime
- 2003-10-08 DE DE60328128T patent/DE60328128D1/de not_active Expired - Lifetime
- 2003-10-08 PL PL379989A patent/PL379989A1/pl not_active Application Discontinuation
- 2003-10-08 MX MXPA05003501A patent/MXPA05003501A/es not_active Application Discontinuation
- 2003-10-08 AU AU2003304060A patent/AU2003304060A1/en not_active Abandoned
- 2003-10-08 AT AT03816571T patent/ATE434625T1/de not_active IP Right Cessation
- 2003-10-08 CA CA002501694A patent/CA2501694A1/en not_active Abandoned
- 2003-10-08 WO PCT/US2003/032113 patent/WO2004096122A2/en active Search and Examination
- 2003-10-08 JP JP2004571457A patent/JP2006517524A/ja not_active Withdrawn
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Also Published As
Publication number | Publication date |
---|---|
AU2003304060A1 (en) | 2004-11-23 |
RU2005113996A (ru) | 2005-10-27 |
WO2004096122A2 (en) | 2004-11-11 |
EP1575522B1 (de) | 2009-06-24 |
ES2326881T3 (es) | 2009-10-21 |
CA2501694A1 (en) | 2004-11-11 |
ES2767744T3 (es) | 2020-06-18 |
UA80447C2 (en) | 2007-09-25 |
EP1575522A2 (de) | 2005-09-21 |
BR0315167A (pt) | 2005-08-23 |
CN1878794A (zh) | 2006-12-13 |
NO20052221L (no) | 2005-07-07 |
MXPA05003501A (es) | 2005-10-19 |
WO2004096122A3 (en) | 2006-06-01 |
CN1878794B (zh) | 2011-11-30 |
JP2006517524A (ja) | 2006-07-27 |
US20040131615A1 (en) | 2004-07-08 |
EP2100902A1 (de) | 2009-09-16 |
KR20050067174A (ko) | 2005-06-30 |
DE60328128D1 (de) | 2009-08-06 |
EP1575522A4 (de) | 2007-05-30 |
NO20052221D0 (no) | 2005-05-06 |
PL379989A1 (pl) | 2006-11-27 |
EP2100902B1 (de) | 2019-12-18 |
ZA200502611B (en) | 2006-06-28 |
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