ATE402147T1 - 1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungen - Google Patents
1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungenInfo
- Publication number
- ATE402147T1 ATE402147T1 AT04800641T AT04800641T ATE402147T1 AT E402147 T1 ATE402147 T1 AT E402147T1 AT 04800641 T AT04800641 T AT 04800641T AT 04800641 T AT04800641 T AT 04800641T AT E402147 T1 ATE402147 T1 AT E402147T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- myhc
- methods
- dihydropyridine
- cardiovascular diseases
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 108020004999 messenger RNA Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51721703P | 2003-11-03 | 2003-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE402147T1 true ATE402147T1 (de) | 2008-08-15 |
Family
ID=34549595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04800641T ATE402147T1 (de) | 2003-11-03 | 2004-11-03 | 1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20050124634A1 (de) |
| EP (1) | EP1685108B1 (de) |
| JP (1) | JP2007510728A (de) |
| AT (1) | ATE402147T1 (de) |
| AU (1) | AU2004285962A1 (de) |
| CA (1) | CA2544772A1 (de) |
| DE (1) | DE602004015321D1 (de) |
| IL (1) | IL175357A0 (de) |
| WO (1) | WO2005042487A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009520833A (ja) * | 2005-12-20 | 2009-05-28 | ギリード・コロラド・インコーポレーテッド | ４，７−ジヒドロチエノ［２，３−ｂ］ピリジン化合物及び医薬組成物 |
| JP2012526840A (ja) * | 2009-05-13 | 2012-11-01 | プロテイン デリヴァリー ソリューションズ エルエルシー | 膜貫通送達のための製剤系 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4920225A (en) * | 1986-12-22 | 1990-04-24 | Laboratoires Syntex S.A. | Resolution of 1,4-dihydropyridine derivatives |
| TW215434B (de) * | 1992-03-07 | 1993-11-01 | Hoechst Ag | |
| CN1823041B (zh) * | 2002-01-18 | 2013-01-02 | 维托尔·玛利亚科学研究基金会 | 1,4-二氢吡啶和吡啶化合物作为钙通道阻滞剂 |
| EP1496905B1 (de) * | 2002-04-22 | 2008-08-13 | Johns Hopkins University School of Medicine | Modulatoren von hedgehog signalpfaden, zusammensetzungen und verwandte verwendungen |
-
2004
- 2004-11-03 WO PCT/US2004/036569 patent/WO2005042487A1/en not_active Ceased
- 2004-11-03 CA CA002544772A patent/CA2544772A1/en not_active Abandoned
- 2004-11-03 AU AU2004285962A patent/AU2004285962A1/en not_active Abandoned
- 2004-11-03 EP EP04800641A patent/EP1685108B1/de not_active Expired - Lifetime
- 2004-11-03 DE DE602004015321T patent/DE602004015321D1/de not_active Expired - Lifetime
- 2004-11-03 US US10/980,612 patent/US20050124634A1/en not_active Abandoned
- 2004-11-03 AT AT04800641T patent/ATE402147T1/de not_active IP Right Cessation
- 2004-11-03 JP JP2006539621A patent/JP2007510728A/ja active Pending
-
2006
- 2006-05-01 IL IL175357A patent/IL175357A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005042487A1 (en) | 2005-05-12 |
| JP2007510728A (ja) | 2007-04-26 |
| IL175357A0 (en) | 2006-09-05 |
| EP1685108B1 (de) | 2008-07-23 |
| EP1685108A1 (de) | 2006-08-02 |
| DE602004015321D1 (de) | 2008-09-04 |
| US20050124634A1 (en) | 2005-06-09 |
| AU2004285962A1 (en) | 2005-05-12 |
| CA2544772A1 (en) | 2005-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |