ATE407925T1 - 1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungen - Google Patents
1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungenInfo
- Publication number
- ATE407925T1 ATE407925T1 AT04800640T AT04800640T ATE407925T1 AT E407925 T1 ATE407925 T1 AT E407925T1 AT 04800640 T AT04800640 T AT 04800640T AT 04800640 T AT04800640 T AT 04800640T AT E407925 T1 ATE407925 T1 AT E407925T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- myhc
- methods
- dihydropyridine
- cardiovascular diseases
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 108020004999 messenger RNA Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51682803P | 2003-11-03 | 2003-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE407925T1 true ATE407925T1 (de) | 2008-09-15 |
Family
ID=34549573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04800640T ATE407925T1 (de) | 2003-11-03 | 2004-11-03 | 1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7485653B2 (de) |
| EP (1) | EP1685107B1 (de) |
| JP (1) | JP2007510727A (de) |
| AT (1) | ATE407925T1 (de) |
| AU (1) | AU2004285961A1 (de) |
| CA (1) | CA2544763A1 (de) |
| DE (1) | DE602004016547D1 (de) |
| IL (1) | IL175358A0 (de) |
| WO (1) | WO2005042486A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110015246A2 (en) * | 2005-03-14 | 2011-01-20 | Agean Llc | Lofexidine enantiomers for use as a treatment for cns disease and pathologies and its chiral synthesis |
| CA2634158A1 (en) * | 2005-12-20 | 2007-06-28 | Gilead Colorado, Inc. | Use of 4, 7-dihydrothieno ¬2, 3-b| pyridine compounds in the treatment of cardiovascular diseases |
| CA2660707C (en) | 2006-08-10 | 2014-07-08 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Preparation of (r,r)-fenoterol and (r,r)- or (r,s)-fenoterol analogues and their use in treating congestive heart failure |
| JP2012526840A (ja) * | 2009-05-13 | 2012-11-01 | プロテイン デリヴァリー ソリューションズ エルエルシー | 膜貫通送達のための製剤系 |
| WO2011112867A1 (en) | 2010-03-10 | 2011-09-15 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | The use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4920225A (en) | 1986-12-22 | 1990-04-24 | Laboratoires Syntex S.A. | Resolution of 1,4-dihydropyridine derivatives |
| TW215434B (de) * | 1992-03-07 | 1993-11-01 | Hoechst Ag | |
| JP2002514199A (ja) | 1997-02-04 | 2002-05-14 | ブリストル−マイヤーズ スクイブ カンパニー | Ｎｐｙ拮抗剤としてのジヒドロピリミドン誘導体 |
| WO2003062201A1 (en) | 2002-01-18 | 2003-07-31 | Vittal Mallya Scientific Research Foundation | 1,4-dihydropyridine and pyridine compounds as calcium channel blockers |
| ATE404200T1 (de) | 2002-04-22 | 2008-08-15 | Univ Johns Hopkins Med | Modulatoren von hedgehog signalpfaden, zusammensetzungen und verwandte verwendungen |
-
2004
- 2004-11-03 DE DE602004016547T patent/DE602004016547D1/de not_active Expired - Lifetime
- 2004-11-03 JP JP2006539620A patent/JP2007510727A/ja active Pending
- 2004-11-03 WO PCT/US2004/036568 patent/WO2005042486A1/en not_active Ceased
- 2004-11-03 AU AU2004285961A patent/AU2004285961A1/en not_active Abandoned
- 2004-11-03 CA CA002544763A patent/CA2544763A1/en not_active Abandoned
- 2004-11-03 EP EP04800640A patent/EP1685107B1/de not_active Expired - Lifetime
- 2004-11-03 US US10/980,605 patent/US7485653B2/en not_active Expired - Fee Related
- 2004-11-03 AT AT04800640T patent/ATE407925T1/de not_active IP Right Cessation
-
2006
- 2006-05-01 IL IL175358A patent/IL175358A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL175358A0 (en) | 2006-09-05 |
| EP1685107A1 (de) | 2006-08-02 |
| JP2007510727A (ja) | 2007-04-26 |
| EP1685107B1 (de) | 2008-09-10 |
| AU2004285961A1 (en) | 2005-05-12 |
| WO2005042486A1 (en) | 2005-05-12 |
| US7485653B2 (en) | 2009-02-03 |
| US20050124633A1 (en) | 2005-06-09 |
| CA2544763A1 (en) | 2005-05-12 |
| DE602004016547D1 (de) | 2008-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |