ATE425750T1 - Verwendung von triglyceriden mit mittellangen ketten zur behandlung und vorbeugung der alzheimerschen erkrankung - Google Patents
Verwendung von triglyceriden mit mittellangen ketten zur behandlung und vorbeugung der alzheimerschen erkrankungInfo
- Publication number
- ATE425750T1 ATE425750T1 AT01930965T AT01930965T ATE425750T1 AT E425750 T1 ATE425750 T1 AT E425750T1 AT 01930965 T AT01930965 T AT 01930965T AT 01930965 T AT01930965 T AT 01930965T AT E425750 T1 ATE425750 T1 AT E425750T1
- Authority
- AT
- Austria
- Prior art keywords
- alzheimer
- disease
- prevention
- treatment
- medium chain
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 229940057917 medium chain triglycerides Drugs 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 230000003920 cognitive function Effects 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20098000P | 2000-05-01 | 2000-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE425750T1 true ATE425750T1 (de) | 2009-04-15 |
Family
ID=22743976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01930965T ATE425750T1 (de) | 2000-05-01 | 2001-05-01 | Verwendung von triglyceriden mit mittellangen ketten zur behandlung und vorbeugung der alzheimerschen erkrankung |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20020006959A1 (enExample) |
| EP (3) | EP1292294B1 (enExample) |
| JP (2) | JP2003531857A (enExample) |
| AT (1) | ATE425750T1 (enExample) |
| AU (1) | AU2001257451A1 (enExample) |
| DE (1) | DE60138019D1 (enExample) |
| DK (1) | DK1292294T3 (enExample) |
| ES (2) | ES2323940T3 (enExample) |
| PT (1) | PT1292294E (enExample) |
| WO (1) | WO2001082928A1 (enExample) |
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| US6323237B1 (en) * | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
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| US20080009467A1 (en) * | 2000-05-01 | 2008-01-10 | Accera, Inc. | Combinations of medium chain triglycerides and therapeutic agents for the treatment and prevention of alzheimers disease and other diseases resulting from reduced neuronal metabolism |
| US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
| US20070179197A1 (en) * | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
| US20060189545A1 (en) * | 2003-03-06 | 2006-08-24 | Henderson Samuel T | Novel chemical entities and methods for their use in treatment of metabolic disorders |
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| US20060280721A1 (en) | 2003-06-03 | 2006-12-14 | The Gov Of Usa Represented By Secretary Of Dpt Of | Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives |
| GB0420856D0 (en) * | 2004-09-20 | 2004-10-20 | Ketocytonyx Inc | Cns modulators |
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| CN115811942A (zh) * | 2020-07-23 | 2023-03-17 | 雀巢产品有限公司 | 用于改善认知功能的mct制剂以及制备和使用此类制剂的方法 |
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| JP2023545769A (ja) * | 2020-10-09 | 2023-10-31 | セレシン・インコーポレーテッド | 制御された薬物動態、安全性および忍容性プロファイルを有する中鎖トリグリセリドを送達するための方法 |
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2001
- 2001-05-01 ES ES01930965T patent/ES2323940T3/es not_active Expired - Lifetime
- 2001-05-01 AT AT01930965T patent/ATE425750T1/de active
- 2001-05-01 WO PCT/US2001/013955 patent/WO2001082928A1/en not_active Ceased
- 2001-05-01 AU AU2001257451A patent/AU2001257451A1/en not_active Abandoned
- 2001-05-01 DK DK01930965T patent/DK1292294T3/da active
- 2001-05-01 JP JP2001579803A patent/JP2003531857A/ja active Pending
- 2001-05-01 US US09/845,741 patent/US20020006959A1/en not_active Abandoned
- 2001-05-01 DE DE60138019T patent/DE60138019D1/de not_active Expired - Lifetime
- 2001-05-01 EP EP01930965A patent/EP1292294B1/en not_active Expired - Lifetime
- 2001-05-01 EP EP09001380.6A patent/EP2065041B1/en not_active Expired - Lifetime
- 2001-05-01 EP EP10181854A patent/EP2319508A1/en not_active Withdrawn
- 2001-05-01 PT PT01930965T patent/PT1292294E/pt unknown
- 2001-05-01 ES ES09001380T patent/ES2752800T3/es not_active Expired - Lifetime
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2006
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- 2012-04-12 US US13/445,679 patent/US8426468B2/en not_active Expired - Fee Related
- 2012-05-07 JP JP2012105692A patent/JP5701245B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2752800T3 (es) | 2020-04-06 |
| DK1292294T3 (da) | 2009-06-22 |
| EP1292294A4 (en) | 2004-04-14 |
| US20060122270A1 (en) | 2006-06-08 |
| EP2065041A1 (en) | 2009-06-03 |
| JP5701245B2 (ja) | 2015-04-15 |
| ES2323940T3 (es) | 2009-07-28 |
| US20120196932A1 (en) | 2012-08-02 |
| AU2001257451A8 (en) | 2006-11-09 |
| PT1292294E (pt) | 2009-06-01 |
| US8426468B2 (en) | 2013-04-23 |
| US20020006959A1 (en) | 2002-01-17 |
| DE60138019D1 (de) | 2009-04-30 |
| EP1292294B1 (en) | 2009-03-18 |
| JP2012188431A (ja) | 2012-10-04 |
| EP2319508A1 (en) | 2011-05-11 |
| AU2001257451A1 (en) | 2001-11-12 |
| EP1292294A1 (en) | 2003-03-19 |
| EP2065041B1 (en) | 2019-07-31 |
| WO2001082928A1 (en) | 2001-11-08 |
| JP2003531857A (ja) | 2003-10-28 |
| WO2001082928A9 (en) | 2006-06-15 |
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