AU2001257451A1 - Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism - Google Patents
Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolismInfo
- Publication number
- AU2001257451A1 AU2001257451A1 AU2001257451A AU5745101A AU2001257451A1 AU 2001257451 A1 AU2001257451 A1 AU 2001257451A1 AU 2001257451 A AU2001257451 A AU 2001257451A AU 5745101 A AU5745101 A AU 5745101A AU 2001257451 A1 AU2001257451 A1 AU 2001257451A1
- Authority
- AU
- Australia
- Prior art keywords
- alzheimer
- disease
- prevention
- treatment
- medium chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 230000004060 metabolic process Effects 0.000 title abstract 2
- 230000001537 neural effect Effects 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940057917 medium chain triglycerides Drugs 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 230000003920 cognitive function Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20098000P | 2000-05-01 | 2000-05-01 | |
| US60/200,980 | 2000-05-01 | ||
| PCT/US2001/013955 WO2001082928A1 (en) | 2000-05-01 | 2001-05-01 | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2001257451A1 true AU2001257451A1 (en) | 2001-11-12 |
| AU2001257451A8 AU2001257451A8 (en) | 2006-11-09 |
Family
ID=22743976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001257451A Abandoned AU2001257451A1 (en) | 2000-05-01 | 2001-05-01 | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20020006959A1 (enExample) |
| EP (3) | EP2319508A1 (enExample) |
| JP (2) | JP2003531857A (enExample) |
| AT (1) | ATE425750T1 (enExample) |
| AU (1) | AU2001257451A1 (enExample) |
| DE (1) | DE60138019D1 (enExample) |
| DK (1) | DK1292294T3 (enExample) |
| ES (2) | ES2752800T3 (enExample) |
| PT (1) | PT1292294E (enExample) |
| WO (1) | WO2001082928A1 (enExample) |
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6323237B1 (en) * | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
| US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
| US20080009467A1 (en) * | 2000-05-01 | 2008-01-10 | Accera, Inc. | Combinations of medium chain triglycerides and therapeutic agents for the treatment and prevention of alzheimers disease and other diseases resulting from reduced neuronal metabolism |
| US20070179197A1 (en) * | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
| EP2319508A1 (en) | 2000-05-01 | 2011-05-11 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of Alzheimer's disease and other diseases resulting from reduced neuronal metabolism |
| EP1605950A4 (en) * | 2003-03-06 | 2008-01-09 | Accera Inc | NOVEL CHEMICAL ENTITIES AND METHODS OF USE IN THE TREATMENT OF METABOLIC DISORDERS |
| GB0306394D0 (en) | 2003-03-20 | 2003-04-23 | Univ Nottingham | Carnitine retention |
| CA2527940C (en) | 2003-06-03 | 2016-03-22 | Richard L. Veech | Nutritional supplements and therapeutic compositions comprising (r)-3-hydroxybutyrate derivatives |
| GB0420856D0 (en) * | 2004-09-20 | 2004-10-20 | Ketocytonyx Inc | Cns modulators |
| EP1778615A4 (en) | 2004-07-20 | 2010-01-06 | Btg Int Ltd | OLIGOMERE KETONE COMPOUNDS |
| EP1796658B1 (en) * | 2004-09-21 | 2016-03-30 | BTG International Limited | Dopaminergic mimetics |
| US7702343B2 (en) * | 2005-04-04 | 2010-04-20 | Qualcomm Incorporated | Efficient gap allocation for cell measurements in asynchronous communication networks |
| US20060252775A1 (en) * | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
| FR2885491B1 (fr) * | 2005-05-16 | 2020-03-06 | Nutricos Technologies | Traitement de la secheresse keratinique par des glycerides |
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| WO2009002166A1 (en) | 2007-06-26 | 2008-12-31 | N.V. Nutricia | Improving memory in subjects with mini-mental state examination of 24-26 |
| WO2009002146A1 (en) | 2007-06-26 | 2008-12-31 | N.V. Nutricia | Supporting activities of daily living |
| WO2009018478A2 (en) * | 2007-07-31 | 2009-02-05 | Accera, Inc. | Use of genomic testing and ketogenic compounds for treatment of reduced cognitive function |
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| KR101734152B1 (ko) | 2008-07-03 | 2017-05-11 | 액세라인크 | 신경계 장애의 치료를 위한 아세토아세테이트의 모노글리세리드 및 유도체 |
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| US11129802B2 (en) | 2018-08-27 | 2021-09-28 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
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-
2001
- 2001-05-01 EP EP10181854A patent/EP2319508A1/en not_active Withdrawn
- 2001-05-01 WO PCT/US2001/013955 patent/WO2001082928A1/en not_active Ceased
- 2001-05-01 EP EP09001380.6A patent/EP2065041B1/en not_active Expired - Lifetime
- 2001-05-01 PT PT01930965T patent/PT1292294E/pt unknown
- 2001-05-01 EP EP01930965A patent/EP1292294B1/en not_active Expired - Lifetime
- 2001-05-01 ES ES09001380T patent/ES2752800T3/es not_active Expired - Lifetime
- 2001-05-01 DK DK01930965T patent/DK1292294T3/da active
- 2001-05-01 DE DE60138019T patent/DE60138019D1/de not_active Expired - Lifetime
- 2001-05-01 AU AU2001257451A patent/AU2001257451A1/en not_active Abandoned
- 2001-05-01 JP JP2001579803A patent/JP2003531857A/ja active Pending
- 2001-05-01 AT AT01930965T patent/ATE425750T1/de active
- 2001-05-01 ES ES01930965T patent/ES2323940T3/es not_active Expired - Lifetime
- 2001-05-01 US US09/845,741 patent/US20020006959A1/en not_active Abandoned
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2006
- 2006-01-13 US US11/331,673 patent/US20060122270A1/en not_active Abandoned
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2012
- 2012-04-12 US US13/445,679 patent/US8426468B2/en not_active Expired - Fee Related
- 2012-05-07 JP JP2012105692A patent/JP5701245B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2752800T3 (es) | 2020-04-06 |
| EP1292294A1 (en) | 2003-03-19 |
| EP2319508A1 (en) | 2011-05-11 |
| JP2012188431A (ja) | 2012-10-04 |
| JP5701245B2 (ja) | 2015-04-15 |
| DE60138019D1 (de) | 2009-04-30 |
| PT1292294E (pt) | 2009-06-01 |
| AU2001257451A8 (en) | 2006-11-09 |
| JP2003531857A (ja) | 2003-10-28 |
| EP2065041B1 (en) | 2019-07-31 |
| EP1292294A4 (en) | 2004-04-14 |
| WO2001082928A9 (en) | 2006-06-15 |
| DK1292294T3 (da) | 2009-06-22 |
| EP2065041A1 (en) | 2009-06-03 |
| WO2001082928A1 (en) | 2001-11-08 |
| ATE425750T1 (de) | 2009-04-15 |
| EP1292294B1 (en) | 2009-03-18 |
| US20020006959A1 (en) | 2002-01-17 |
| US20120196932A1 (en) | 2012-08-02 |
| ES2323940T3 (es) | 2009-07-28 |
| US8426468B2 (en) | 2013-04-23 |
| US20060122270A1 (en) | 2006-06-08 |
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