DE60318081D1 - Verwendung von brimonidine zur behandlung von dementia und morbus parkinson - Google Patents
Verwendung von brimonidine zur behandlung von dementia und morbus parkinsonInfo
- Publication number
- DE60318081D1 DE60318081D1 DE60318081T DE60318081T DE60318081D1 DE 60318081 D1 DE60318081 D1 DE 60318081D1 DE 60318081 T DE60318081 T DE 60318081T DE 60318081 T DE60318081 T DE 60318081T DE 60318081 D1 DE60318081 D1 DE 60318081D1
- Authority
- DE
- Germany
- Prior art keywords
- brimonidine
- dementia
- treatment
- morbus parkinson
- parkinson
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41703102P | 2002-10-08 | 2002-10-08 | |
US417031P | 2002-10-08 | ||
PCT/US2003/031842 WO2004032934A1 (en) | 2002-10-08 | 2003-10-07 | Method of using (2-imidazolin-2-ylamino) qinoxalines in the treatment of dementia and parkinsons |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60318081D1 true DE60318081D1 (de) | 2008-01-24 |
DE60318081T2 DE60318081T2 (de) | 2008-11-06 |
Family
ID=32093952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60318081T Expired - Lifetime DE60318081T2 (de) | 2002-10-08 | 2003-10-07 | Verwendung von brimonidine zur behandlung von dementia und morbus parkinson |
Country Status (20)
Country | Link |
---|---|
US (1) | US20040116436A1 (de) |
EP (1) | EP1549314B1 (de) |
JP (1) | JP2006504741A (de) |
KR (1) | KR20050056235A (de) |
CN (1) | CN100370988C (de) |
AT (1) | ATE380551T1 (de) |
AU (2) | AU2003279874A1 (de) |
BR (1) | BR0314541A (de) |
CA (1) | CA2501348A1 (de) |
DE (1) | DE60318081T2 (de) |
ES (1) | ES2297233T3 (de) |
HK (1) | HK1080408B (de) |
IL (1) | IL167848A (de) |
MX (1) | MXPA05003665A (de) |
NO (1) | NO20051664L (de) |
NZ (1) | NZ539329A (de) |
PL (1) | PL376347A1 (de) |
RU (1) | RU2332218C2 (de) |
WO (1) | WO2004032934A1 (de) |
ZA (1) | ZA200502745B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7512436B2 (en) * | 2004-02-12 | 2009-03-31 | The Regents Of The University Of Michigan | Method of evaluating metabolism of the eye |
US9095506B2 (en) | 2008-11-17 | 2015-08-04 | Allergan, Inc. | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
US20100298305A1 (en) * | 2008-11-26 | 2010-11-25 | The United States Government, As Represented By The Department Of Veterans Affairs | Tizanidine for the treatment of post-traumatic stress disorder and nightmares |
DE102009043750A1 (de) * | 2009-09-30 | 2011-08-04 | Carl Zeiss Meditec AG, 07745 | Verfahren und Vorrichtung zur Detektion von Ablagerungen im Auge |
US10022341B2 (en) * | 2014-12-02 | 2018-07-17 | Yale University | Methods of preventing neurodegeneration of association cortex in a mammal |
RU2680526C1 (ru) * | 2016-07-05 | 2019-02-22 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) | Нейропротекторное средство, обладающее свойствами антиоксиданта и донатора оксида азота |
EP3491391A4 (de) * | 2016-08-01 | 2020-04-29 | Cognoptix, Inc. | System und verfahren zur erkennung von tau-protein in augengewebe |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE795970A (fr) * | 1972-02-29 | 1973-08-27 | Pfizer | Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant |
US4029792A (en) * | 1972-02-29 | 1977-06-14 | Pfizer Inc. | (2-Imidazolin-2-ylamino) substituted -quinoxalines and -quinazolines as antihypertensive agents |
US5210076A (en) * | 1988-09-13 | 1993-05-11 | Berliner David L | Methods of treating Parkinson's disease using melanin |
RU2176145C2 (ru) * | 1995-05-26 | 2001-11-27 | Пфайзер Инк. | Синергическое лечение паркинсонизма |
US6194415B1 (en) * | 1995-06-28 | 2001-02-27 | Allergan Sales, Inc. | Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury |
US6841684B2 (en) * | 1997-12-04 | 2005-01-11 | Allergan, Inc. | Imidiazoles having reduced side effects |
US6329369B1 (en) * | 1997-12-04 | 2001-12-11 | Allergan Sales, Inc. | Methods of treating pain and other conditions |
IL136388A0 (en) * | 1997-12-04 | 2001-06-14 | Allergan Sales Inc | Substituted imidazole derivatives having agonist-like activity at alpha 2b or 2b/2c adrenergic receptors |
US6313172B1 (en) * | 2000-04-13 | 2001-11-06 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
WO2002005853A2 (en) * | 2000-07-14 | 2002-01-24 | Allergan, Inc. | Compositions containing alpha-2-adrenergic agonist components |
-
2003
- 2003-10-07 PL PL03376347A patent/PL376347A1/xx not_active Application Discontinuation
- 2003-10-07 RU RU2005114505/14A patent/RU2332218C2/ru not_active IP Right Cessation
- 2003-10-07 DE DE60318081T patent/DE60318081T2/de not_active Expired - Lifetime
- 2003-10-07 MX MXPA05003665A patent/MXPA05003665A/es active IP Right Grant
- 2003-10-07 KR KR1020057006115A patent/KR20050056235A/ko not_active Application Discontinuation
- 2003-10-07 WO PCT/US2003/031842 patent/WO2004032934A1/en active IP Right Grant
- 2003-10-07 US US10/680,996 patent/US20040116436A1/en not_active Abandoned
- 2003-10-07 NZ NZ539329A patent/NZ539329A/en not_active IP Right Cessation
- 2003-10-07 BR BR0314541-7A patent/BR0314541A/pt not_active IP Right Cessation
- 2003-10-07 ES ES03773199T patent/ES2297233T3/es not_active Expired - Lifetime
- 2003-10-07 AU AU2003279874A patent/AU2003279874A1/en not_active Abandoned
- 2003-10-07 EP EP03773199A patent/EP1549314B1/de not_active Expired - Lifetime
- 2003-10-07 JP JP2004543508A patent/JP2006504741A/ja active Pending
- 2003-10-07 AT AT03773199T patent/ATE380551T1/de not_active IP Right Cessation
- 2003-10-07 CA CA002501348A patent/CA2501348A1/en not_active Abandoned
- 2003-10-07 CN CNB2003801011164A patent/CN100370988C/zh not_active Expired - Fee Related
-
2005
- 2005-04-04 NO NO20051664A patent/NO20051664L/no not_active Application Discontinuation
- 2005-04-04 IL IL167848A patent/IL167848A/en not_active IP Right Cessation
- 2005-04-05 ZA ZA200502745A patent/ZA200502745B/en unknown
-
2006
- 2006-01-04 HK HK06100172.4A patent/HK1080408B/zh not_active IP Right Cessation
-
2010
- 2010-02-26 AU AU2010200730A patent/AU2010200730A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2297233T3 (es) | 2008-05-01 |
ATE380551T1 (de) | 2007-12-15 |
NO20051664L (no) | 2005-05-31 |
RU2005114505A (ru) | 2005-10-27 |
AU2003279874A1 (en) | 2004-05-04 |
NZ539329A (en) | 2007-11-30 |
WO2004032934A1 (en) | 2004-04-22 |
DE60318081T2 (de) | 2008-11-06 |
HK1080408A1 (en) | 2006-04-28 |
BR0314541A (pt) | 2005-07-26 |
CN100370988C (zh) | 2008-02-27 |
MXPA05003665A (es) | 2005-06-08 |
ZA200502745B (en) | 2006-07-26 |
IL167848A (en) | 2010-11-30 |
CN1703222A (zh) | 2005-11-30 |
US20040116436A1 (en) | 2004-06-17 |
AU2010200730A1 (en) | 2010-03-18 |
HK1080408B (zh) | 2008-08-08 |
KR20050056235A (ko) | 2005-06-14 |
EP1549314B1 (de) | 2007-12-12 |
CA2501348A1 (en) | 2004-04-22 |
PL376347A1 (en) | 2005-12-27 |
EP1549314A1 (de) | 2005-07-06 |
JP2006504741A (ja) | 2006-02-09 |
RU2332218C2 (ru) | 2008-08-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60132777D1 (de) | Benzothiazolderivate zur behandlung von alzheimer und parkinson | |
DE60325770D1 (de) | Verwendung von rimexolon zur behandlung von augentrockenheit | |
DE60010702D1 (de) | Behandlung von titanerz zur herstellung von titandioxidpigmenten | |
ATE354563T1 (de) | Sulfonderivate zur hemmung von gamma-secretase | |
ATE361067T1 (de) | Naphtoquinone derivate als inhibitoren von tau aggregation zur behandlung von alzheimer's und verbundenen neurodegenerativen erkrankungen | |
ATE396174T1 (de) | Hydroxyalkylaminderivate als beta-secretase- inhibitoren und deren verwendung zur behandlung der alzheimerschen krankheit oder ähnlicher krankheiten | |
ATE409176T1 (de) | 1-phenylalkancarbonsäurederivate zur behandlung neurodegenerativer erkrankungen | |
ATE383853T1 (de) | Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit | |
ATE325808T1 (de) | 5-beta-sapogenin und pseudosapogeninderivate und ihre verwendung zur behandlung von demenz | |
ATE384699T1 (de) | 2,6-chinolinyl- und 2,6-naphthylderivate und deren verwendungen zur behandlung von vla-4 bezogenen krankheiten | |
NO20052153L (no) | Piperazin- og piperidinderivater for behandling av nevrologiske sykdommer. | |
DE60312736D1 (de) | 1,2,4-triaminobenzolderivate zur behandlung von erkrankungen des zentralnervensystems | |
ATE427928T1 (de) | Fluorobenzamide zur behandlung von alzheimer oder seniler dementia | |
NO20051664L (no) | Behandling av demens og Parkinsons sykdom | |
DE602004021847D1 (de) | Verfahren zur prävention und behandlung von diabetes mit neurturin | |
DE602005015697D1 (de) | Te zur behandlung von alzheimer-krankheit | |
DE60218153D1 (de) | Verwendung von proteasom-inhibitoren zur behandlung des trockenen auges | |
DE50114605D1 (de) | No-thien-2-yl-essigsaure-derivate und ihre verwendung zur behandlung von migraine bzw. schmerz | |
DE602005017762D1 (de) | Methode zur behandlung trockener augen und uveitis | |
ATE464048T1 (de) | Behandlung von alzheimer-krankheit und verwandten zuständen | |
ATE294584T1 (de) | Verwendung von desoxypeganin zur behandlung von alzheimerischer demenz | |
ATE390134T1 (de) | (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4- fluorophenyl)ethyl)-4-piperidinemethanol oder prodrug davon zur behandlung von demenzsymptomen oder kognitiven störungen | |
DE60018200D1 (de) | Verwendung von pleuromutilinderivaten zur transdermalen behandlung bakterieller erkrankungen | |
ATE328887T1 (de) | Kondensierte heterocyclische verbindungen und ihre verwendung zur behandlung von neurodegenerativen erkrankungen | |
DE60327335D1 (de) | Alpha 2b oder 2b/2c adrenozeptor-agonisten zur behandlung von morbus alzheimer und morbus parkinson |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |