ATE403872T1 - Massenspektormetrie-verfahren - Google Patents
Massenspektormetrie-verfahrenInfo
- Publication number
- ATE403872T1 ATE403872T1 AT04014463T AT04014463T ATE403872T1 AT E403872 T1 ATE403872 T1 AT E403872T1 AT 04014463 T AT04014463 T AT 04014463T AT 04014463 T AT04014463 T AT 04014463T AT E403872 T1 ATE403872 T1 AT E403872T1
- Authority
- AT
- Austria
- Prior art keywords
- molecules
- physico
- chemical properties
- look
- mass
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6872—Methods for sequencing involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0031—Step by step routines describing the use of the apparatus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Optics & Photonics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Glass Compositions (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34046001P | 2001-12-08 | 2001-12-08 | |
| US36484702P | 2002-03-14 | 2002-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE403872T1 true ATE403872T1 (de) | 2008-08-15 |
Family
ID=26992114
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04014463T ATE403872T1 (de) | 2001-12-08 | 2002-12-09 | Massenspektormetrie-verfahren |
| AT02783317T ATE327512T1 (de) | 2001-12-08 | 2002-12-09 | Massenspektrometrie-verfahren |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02783317T ATE327512T1 (de) | 2001-12-08 | 2002-12-09 | Massenspektrometrie-verfahren |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20050092910A1 (de) |
| EP (1) | EP1456667B2 (de) |
| JP (2) | JP4767496B2 (de) |
| AT (2) | ATE403872T1 (de) |
| CA (1) | CA2465297C (de) |
| DE (2) | DE60228132D1 (de) |
| GB (1) | GB2385918B (de) |
| WO (1) | WO2003054549A2 (de) |
Families Citing this family (104)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020115056A1 (en) * | 2000-12-26 | 2002-08-22 | Goodlett David R. | Rapid and quantitative proteome analysis and related methods |
| IL161498A0 (en) * | 2001-10-24 | 2004-09-27 | Univ California | Measurement of protein synthesis rates in humans and experimental system by use of isotopically labeled water |
| CA2466837A1 (en) * | 2001-11-13 | 2003-05-22 | Caprion Pharmaceuticals Inc. | Mass intensity profiling system and uses thereof |
| ATE403872T1 (de) | 2001-12-08 | 2008-08-15 | Micromass Ltd | Massenspektormetrie-verfahren |
| WO2003068919A2 (en) | 2002-02-12 | 2003-08-21 | The Regents Of The University Of California | Non-invasive method for measuring rates of biosynthesis of biological molecules by label incorporation |
| GB0305796D0 (en) * | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
| WO2004011426A2 (en) | 2002-07-30 | 2004-02-05 | The Regents Of The University Of California | Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry |
| AU2003268416A1 (en) * | 2002-09-04 | 2004-03-29 | The Regents Of The University Of California | Methods for measuring rates of replication and death of nfectious microbial agents in an infected host organism |
| ATE415486T1 (de) * | 2002-09-13 | 2008-12-15 | Univ California | Verfahren zur messung der geschwindigkeiten des cholesterinrückwärtstransports in vivo als index für anti-artherogenese |
| US20070248540A1 (en) * | 2002-09-16 | 2007-10-25 | The Regents Of The University Of California | Biochemical methods for measuring metabolic fitness of tissues or whole organisms |
| AU2003291731B2 (en) | 2002-11-04 | 2009-09-10 | The Regents Of The University Of California | Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body |
| AU2003294165A1 (en) * | 2002-11-22 | 2004-06-18 | Caprion Pharmaceuticals, Inc. | Constellation mapping and uses thereof |
| US7262020B2 (en) * | 2003-07-03 | 2007-08-28 | The Regents Of The University Of California | Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol |
| GB0322356D0 (en) * | 2003-09-24 | 2003-10-22 | Micromass Ltd | Mass spectrometer |
| JP2007507771A (ja) * | 2003-10-01 | 2007-03-29 | プロテオム システムズ インテレクチュアル プロパティ プロプライエタリー リミテッド | 候補組成物又は候補構造体の生物学的尤度を決定する方法 |
| US7759130B2 (en) * | 2003-11-21 | 2010-07-20 | Eisai R & D Management Co., Ltd. | Mass spectrometric quantitation method for biomolecules based on metabolically labeled internal standards |
| US20050202406A1 (en) | 2003-11-25 | 2005-09-15 | The Regents Of The University Of California | Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems |
| JP4284167B2 (ja) * | 2003-12-24 | 2009-06-24 | 株式会社日立ハイテクノロジーズ | イオントラップ/飛行時間型質量分析計による精密質量測定方法 |
| WO2005079261A2 (en) * | 2004-02-13 | 2005-09-01 | Waters Investments Limited | System and method for tracking and quatitating chemical entites |
| TW200538738A (en) | 2004-02-20 | 2005-12-01 | Univ California | Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity |
| WO2005087943A1 (en) * | 2004-03-11 | 2005-09-22 | The Regents Of The University Of California | Temporal or spatial characterization of biosynthetic events in living organisms by isotopic fingerprinting under conditions of imposed isotopic gradients |
| US20050238577A1 (en) * | 2004-03-29 | 2005-10-27 | The Regents Of The University Of California | Isolation of epithelial cells or their biochemical contents from excreta after in vivo isotopic labeling |
| JP5008564B2 (ja) | 2004-05-20 | 2012-08-22 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 混合物中のタンパク質を同定する方法および装置 |
| GB0415046D0 (en) | 2004-07-05 | 2004-08-04 | Micromass Ltd | Mass spectrometer |
| AU2005263334C1 (en) * | 2004-07-20 | 2011-01-20 | Symphogen A/S | A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| US7910372B2 (en) | 2004-07-29 | 2011-03-22 | Eisai R&D Management Co., Ltd. | Absolute quantitation of protein contents based on exponentially modified protein abundance index by mass spectrometry |
| NZ536082A (en) * | 2004-10-22 | 2007-06-29 | Syft Technologies Ltd | Detection of bromamines and chloramines in breath samples for detecting asthma |
| JP4118918B2 (ja) * | 2005-02-28 | 2008-07-16 | シャープ株式会社 | 信号品質評価装置、情報記録再生装置、信号品質評価方法、記録条件決定方法、信号品質評価プログラム、信号品質評価プログラムを記録したコンピュータ読み取り可能な記録媒体 |
| CA2602615A1 (en) * | 2005-04-04 | 2006-10-12 | Viventia Biotech Inc. | Method and system for identification of antigen |
| US7447597B2 (en) * | 2005-05-06 | 2008-11-04 | Exxonmobil Research And Engineering Company | Data processing/visualization method for two (multi) dimensional separation gas chromatography xmass spectrometry (GCxMS) technique with a two (multiply) dimensional separation concept as an example |
| EP1889079B1 (de) * | 2005-06-03 | 2022-08-31 | Waters Technologies Corporation | Verfahren zur ausführung der abstimmung der verweilzeit |
| JP5011283B2 (ja) * | 2005-06-03 | 2012-08-29 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 化学分析のためのポリペプチド関連情報のカタログの発生および使用 |
| WO2006128297A1 (en) * | 2005-06-03 | 2006-12-07 | Mds Inc. Doing Business Through Its Mds Sciex Division | System and method for analysis of compounds using a mass spectrometer |
| EP1894019A4 (de) * | 2005-06-03 | 2011-02-09 | Mds Inc Doing Business Through Its Mds Sciex Division | System und verfahren zur datensammlung bei der rekursiven massenanalyse |
| TW200711660A (en) * | 2005-06-10 | 2007-04-01 | Univ California | Monitoring two dimensions of diabetes pathogenesis separately or concurrently (insulin sensitivity and beta-cell sufficiency): uses in diagnosis, prognosis, assessment of disease risk, and drug development |
| US20060287834A1 (en) * | 2005-06-16 | 2006-12-21 | Kearney Paul E | Virtual mass spectrometry |
| IN2014DN02241A (de) | 2005-06-30 | 2015-07-10 | Biocrates Life Sciences Ag | |
| JP4659831B2 (ja) | 2005-07-29 | 2011-03-30 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 化合物に対するタンパク質の結合力を解析する方法 |
| JP2009507212A (ja) * | 2005-09-02 | 2009-02-19 | オーストラリアン ヌークリア サイエンス アンド テクノロジー オーガニゼイション | 同位体比質量分析計および同位体比の決定方法 |
| JPWO2007029431A1 (ja) * | 2005-09-07 | 2009-03-12 | ヒューマン・メタボローム・テクノロジーズ株式会社 | 質量分析装置の検出質量較正方法 |
| WO2007072648A1 (ja) * | 2005-12-21 | 2007-06-28 | Japan Health Sciences Foundation | 質量分析システムおよび質量分析方法 |
| US20070218505A1 (en) * | 2006-03-14 | 2007-09-20 | Paul Kearney | Identification of biomolecules through expression patterns in mass spectrometry |
| GB0609253D0 (en) * | 2006-05-10 | 2006-06-21 | Micromass Ltd | Mass spectrometer |
| US9063162B2 (en) * | 2006-05-26 | 2015-06-23 | Waters Technologies Corporation | Apparatus and method for performing mass spectroscopy |
| WO2007140251A2 (en) * | 2006-05-26 | 2007-12-06 | Waters Investments Limited | Apparatus and method for performing mass spectroscopy |
| US20080073499A1 (en) * | 2006-07-25 | 2008-03-27 | George Yefchak | Peak finding in low-resolution mass spectrometry by use of chromatographic integration routines |
| RU2009113801A (ru) * | 2006-09-14 | 2010-10-20 | Конинклейке Филипс Электроникс Н.В. (Nl) | Способы анализа образцов белков на основе идентификации с-концевых пептидов |
| US7499807B1 (en) * | 2006-09-19 | 2009-03-03 | Battelle Memorial Institute | Methods for recalibration of mass spectrometry data |
| WO2008060929A1 (en) * | 2006-11-09 | 2008-05-22 | Alcon Research, Ltd. | Punctal plug comprising a water-insoluble polymeric matrix |
| EP2118652B1 (de) * | 2006-12-26 | 2012-05-23 | Brigham Young University | Serumproteomiksystem und damit zusammenhängende verfahren |
| US7595485B1 (en) * | 2007-02-07 | 2009-09-29 | Thermo Finnigan Llc | Data analysis to provide a revised data set for use in peptide sequencing determination |
| US20080226133A1 (en) * | 2007-03-14 | 2008-09-18 | Jean-Luc Truche | Use of Optical Sensors for Spray Jet Diagnostics |
| US8399827B1 (en) * | 2007-09-10 | 2013-03-19 | Cedars-Sinai Medical Center | Mass spectrometry systems |
| EP2279260B1 (de) * | 2008-05-29 | 2021-07-21 | Waters Technologies Corporation | Verfahren zur durchführung eines verweilzeitabgleichs von vorläufer- und produkt-ionen sowie zur herstellung von vorläufer- und produkt-ionen-spektren |
| WO2010002819A1 (en) | 2008-07-01 | 2010-01-07 | Waters Technologies Corporation | Stacked-electrode peptide-fragmentation device |
| US20100224770A1 (en) * | 2009-03-06 | 2010-09-09 | Ensco, Inc. | Method for configuring an ion mobility spectrometer system |
| US9500572B2 (en) * | 2009-04-30 | 2016-11-22 | Purdue Research Foundation | Sample dispenser including an internal standard and methods of use thereof |
| US8987662B2 (en) * | 2009-05-14 | 2015-03-24 | Agilent Technologies, Inc. | System and method for performing tandem mass spectrometry analysis |
| US20110042564A1 (en) * | 2009-08-20 | 2011-02-24 | Yasuhide Naito | Laser ablation mass analyzing apparatus |
| US9453845B2 (en) * | 2010-02-01 | 2016-09-27 | Cell Signaling Technology, Inc. | Mass spectroscopy analysis of mutant polypeptides in biological samples |
| US10553412B2 (en) * | 2010-05-24 | 2020-02-04 | Agilent Technologies, Inc. | System and method of data-dependent acquisition by mass spectrometry |
| US9530633B2 (en) * | 2010-05-25 | 2016-12-27 | Agilent Technologies, Inc. | Method for isomer discrimination by tandem mass spectrometry |
| US20140051092A1 (en) * | 2011-04-15 | 2014-02-20 | Micromass Uk Limited | Method And Apparatus For The Analysis Of Biological Samples |
| JP5736235B2 (ja) * | 2011-05-23 | 2015-06-17 | 株式会社日立製作所 | 質量分析システム及びコンピュータプログラム |
| JP2014526685A (ja) | 2011-09-08 | 2014-10-06 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 代謝流量測定、画像化、および顕微鏡法 |
| CN104024856B (zh) * | 2011-11-04 | 2018-10-26 | 生物辐射实验室股份有限公司 | 基于pI的蛋白质分级 |
| EP2773221B1 (de) | 2011-11-04 | 2019-01-09 | Bio-Rad Laboratories, Inc. | Gleichzeitige reinigung von zellkomponenten |
| US9766207B2 (en) | 2011-11-04 | 2017-09-19 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of pH |
| JP6294233B2 (ja) | 2011-12-07 | 2018-03-14 | グラクソスミスクライン エルエルシー | 全身骨格筋量の定量方法 |
| CN104254390B (zh) | 2012-02-15 | 2017-05-10 | 生物辐射实验室股份有限公司 | pH和离子强度的电子控制 |
| US9321012B2 (en) | 2012-04-04 | 2016-04-26 | Bio-Rad Laboratories, Inc. | Electronic protein fractionation |
| CA2871346A1 (en) * | 2012-04-25 | 2013-10-31 | Atonarp Inc. | System that provides content |
| US9169331B2 (en) | 2012-12-21 | 2015-10-27 | Dionex Corporation | Separation of glycans by mixed-mode liquid chromatography |
| US9310344B2 (en) | 2013-06-14 | 2016-04-12 | Dionex Corporation | HILIC/anion-exchange/cation-exchange multimodal media |
| PT3387898T (pt) * | 2013-03-15 | 2020-06-17 | Mayo Found Medical Education & Res | Identificação e monitorização de imunoglobulinas monoclonais pela massa molecular |
| US9134319B2 (en) | 2013-03-15 | 2015-09-15 | The Regents Of The University Of California | Method for replacing biomarkers of protein kinetics from tissue samples by biomarkers of protein kinetics from body fluids after isotopic labeling in vivo |
| GB201306868D0 (en) | 2013-04-15 | 2013-05-29 | Micromass Ltd | A method of screening samples |
| US9620344B2 (en) | 2013-06-25 | 2017-04-11 | Purdue Research Foundation | Mass spectrometry analysis of microorganisms in samples |
| WO2015082889A1 (en) * | 2013-12-02 | 2015-06-11 | Micromass Uk Limited | Method of charge state selection |
| US10153146B2 (en) | 2014-03-28 | 2018-12-11 | Wisconsin Alumni Research Foundation | High mass accuracy filtering for improved spectral matching of high-resolution gas chromatography-mass spectrometry data against unit-resolution reference databases |
| EP3126826B1 (de) | 2014-04-04 | 2020-12-16 | Mayo Foundation for Medical Education and Research | Isotypisierung von immunglobulinen unter verwendung einer genauen molekülmasse |
| US9720001B2 (en) * | 2014-05-21 | 2017-08-01 | Thermo Finnigan Llc | Methods for mass spectrometric biopolymer analysis using optimized weighted oligomer scheduling |
| US10690676B2 (en) | 2014-07-29 | 2020-06-23 | Mayo Roundation for Medical Education and Research | Quantifying monoclonal antibody therapeutics by LC-MS/MS |
| US10041907B2 (en) * | 2014-09-26 | 2018-08-07 | Micromass Uk Limited | Accurate mobility chromatograms |
| EP3304382B1 (de) | 2015-05-29 | 2025-10-22 | Waters Technologies Corporation | Techniken zur verarbeitung von massenspektraldaten |
| GB201509402D0 (en) * | 2015-06-01 | 2015-07-15 | Micromass Ltd | Lock mass library for internal correction |
| US9847216B2 (en) * | 2015-08-14 | 2017-12-19 | Thermo Finnigan Llc | Systems and methods for targeted top down discovery |
| WO2017053932A1 (en) | 2015-09-24 | 2017-03-30 | Mayo Foundation For Medical Education And Research | Identification of immunoglobulin free light chains by mass spectrometry |
| WO2017060991A1 (ja) * | 2015-10-07 | 2017-04-13 | 株式会社島津製作所 | タンデム型質量分析装置 |
| AU2017325022B2 (en) | 2016-09-07 | 2022-10-13 | Mayo Foundation For Medical Education And Research | Identification and monitoring of cleaved immunoglobulins by molecular mass |
| CN110352354B (zh) | 2017-02-28 | 2024-05-10 | 沃特世科技公司 | 用于分析完整蛋白质、抗体、抗体亚基和抗体药物缀合物的装置和方法 |
| US9911587B1 (en) * | 2017-03-10 | 2018-03-06 | Thermo Finnigan Llc | Methods and systems for quantitative mass analysis |
| US9911588B1 (en) * | 2017-03-10 | 2018-03-06 | Thermo Finnigan Llc | Methods and systems for quantitative mass analysis |
| US10347477B2 (en) | 2017-03-24 | 2019-07-09 | Thermo Finnigan Llc | Methods and systems for quantitative mass analysis |
| WO2019021133A1 (en) * | 2017-07-25 | 2019-01-31 | Biocon Limited | PEPTIDE CARTOGRAPHY METHOD FOR IDENTIFYING INSULIN SEQUENCES AND INSULIN ANALOGUES |
| US12153052B2 (en) | 2017-09-13 | 2024-11-26 | Mayo Foundation For Medical Education And Research | Identification and monitoring of immunoglobulin J chains |
| WO2019055634A1 (en) | 2017-09-13 | 2019-03-21 | Mayo Foundation For Medical Education And Research | IDENTIFICATION AND MONITORING OF A MACROPHAGE APOPTOSIS INHIBITOR |
| WO2020152871A1 (ja) * | 2019-01-25 | 2020-07-30 | 株式会社島津製作所 | クロマトグラフを用いた物質同定方法 |
| JP7306676B2 (ja) * | 2019-02-26 | 2023-07-11 | 国立大学法人九州大学 | 脂質プロファイリングシステム、脂質プロファイリング方法、及び脂質プロファイリングプログラム |
| BE1027232B1 (fr) * | 2019-08-28 | 2020-11-20 | Zentech S A | Procédé de détection d'au moins un variant de protéine et/ou d'au moins un peptide propre aux chaînes alpha et/ou bêta et/ou delta d'hémoglobine |
| EP4139673B1 (de) * | 2020-04-24 | 2026-01-28 | Waters Technologies Ireland Limited | Verfahren zum vergleich von daten in und zwischen kohorten |
| WO2022146812A1 (en) * | 2020-12-30 | 2022-07-07 | Purdue Research Foundation | Mass spectrometry to identify predictive failure with chemical detection in microelectronic systems |
| US12540922B2 (en) * | 2021-05-11 | 2026-02-03 | Wisconsin Alumni Research Foundation | Quantitative shotgun proteome, lipidome, and metabolome analysis by direct infusion |
| US20240371465A1 (en) * | 2023-05-02 | 2024-11-07 | National Central University | Method, system, and computer readable medium for post-translational modifications detection |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB870203A (en) * | 1949-10-26 | 1961-06-14 | Edward Whitworth | Improvements in or relating to surface moderated propellent powders |
| US4735777A (en) * | 1985-03-11 | 1988-04-05 | Hitachi, Ltd. | Instrument for parallel analysis of metabolites in human urine and expired air |
| JP3001252B2 (ja) * | 1990-11-16 | 2000-01-24 | 株式会社日立製作所 | 半導体メモリ |
| US5428621A (en) * | 1992-09-21 | 1995-06-27 | Sundisk Corporation | Latent defect handling in EEPROM devices |
| US5538897A (en) * | 1994-03-14 | 1996-07-23 | University Of Washington | Use of mass spectrometry fragmentation patterns of peptides to identify amino acid sequences in databases |
| US6323482B1 (en) * | 1997-06-02 | 2001-11-27 | Advanced Research And Technology Institute, Inc. | Ion mobility and mass spectrometer |
| EP1095267A1 (de) * | 1998-07-10 | 2001-05-02 | Cetek Corporation | Verfahren zur feststellung und analyse von stark bindenden liganden in komplexen biologischen proben |
| US6147344A (en) * | 1998-10-15 | 2000-11-14 | Neogenesis, Inc | Method for identifying compounds in a chemical mixture |
| US20020009394A1 (en) | 1999-04-02 | 2002-01-24 | Hubert Koster | Automated process line |
| US6936424B1 (en) * | 1999-11-16 | 2005-08-30 | Matritech, Inc. | Materials and methods for detection and treatment of breast cancer |
| CA2298181C (en) | 2000-02-02 | 2006-09-19 | Dayan Burke Goodnough | Non-targeted complex sample analysis |
| DE60127813T2 (de) * | 2000-02-07 | 2007-12-27 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zur identifizierung und/oder charakterisierung eines (poly)peptides |
| CA2400484A1 (en) * | 2000-02-08 | 2001-08-16 | The Regents Of The University Of Michigan | Protein separation and display |
| JP2001330599A (ja) | 2000-05-24 | 2001-11-30 | Shimazu S D Kk | Gc/msによる代謝異常スクリーニング診断装置 |
| US20020115056A1 (en) * | 2000-12-26 | 2002-08-22 | Goodlett David R. | Rapid and quantitative proteome analysis and related methods |
| EP1710577B1 (de) | 2000-12-26 | 2010-07-21 | The Institute for Systems Biology | Schnelle und quantitative Proteomanalyse und entsprechende Verfahren |
| US20020119490A1 (en) * | 2000-12-26 | 2002-08-29 | Aebersold Ruedi H. | Methods for rapid and quantitative proteome analysis |
| US6931325B2 (en) * | 2001-02-07 | 2005-08-16 | Regents Of The University Of Michigan | Three dimensional protein mapping |
| US20030031350A1 (en) | 2001-03-09 | 2003-02-13 | Pe Corporation (Ny) | Methods for large scale protein matching |
| US6835927B2 (en) * | 2001-10-15 | 2004-12-28 | Surromed, Inc. | Mass spectrometric quantification of chemical mixture components |
| CA2466837A1 (en) | 2001-11-13 | 2003-05-22 | Caprion Pharmaceuticals Inc. | Mass intensity profiling system and uses thereof |
| DE10158860B4 (de) | 2001-11-30 | 2007-04-05 | Bruker Daltonik Gmbh | Massenspektrometrische Proteingemischanalyse |
| ATE403872T1 (de) | 2001-12-08 | 2008-08-15 | Micromass Ltd | Massenspektormetrie-verfahren |
| US6835027B1 (en) * | 2003-11-05 | 2004-12-28 | Billy Glass | Staple for securing geo-textile material to the ground |
-
2002
- 2002-12-09 AT AT04014463T patent/ATE403872T1/de not_active IP Right Cessation
- 2002-12-09 EP EP02783317A patent/EP1456667B2/de not_active Expired - Lifetime
- 2002-12-09 DE DE60228132T patent/DE60228132D1/de not_active Expired - Lifetime
- 2002-12-09 US US10/497,896 patent/US20050092910A1/en not_active Abandoned
- 2002-12-09 AT AT02783317T patent/ATE327512T1/de not_active IP Right Cessation
- 2002-12-09 GB GB0228653A patent/GB2385918B/en not_active Expired - Lifetime
- 2002-12-09 CA CA2465297A patent/CA2465297C/en not_active Expired - Fee Related
- 2002-12-09 JP JP2003555211A patent/JP4767496B2/ja not_active Expired - Fee Related
- 2002-12-09 DE DE60211744T patent/DE60211744T3/de not_active Expired - Lifetime
- 2002-12-09 WO PCT/GB2002/005571 patent/WO2003054549A2/en not_active Ceased
-
2004
- 2004-07-16 US US10/893,415 patent/US8030089B2/en not_active Expired - Lifetime
- 2004-07-16 US US10/892,768 patent/US20080286764A9/en not_active Abandoned
- 2004-07-16 US US10/893,212 patent/US20080135744A1/en not_active Abandoned
-
2007
- 2007-10-11 JP JP2007265544A patent/JP4654230B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003054549A2 (en) | 2003-07-03 |
| DE60211744D1 (de) | 2006-06-29 |
| EP1456667B1 (de) | 2006-05-24 |
| ATE327512T1 (de) | 2006-06-15 |
| JP2005513481A (ja) | 2005-05-12 |
| EP1456667A2 (de) | 2004-09-15 |
| US20080286764A9 (en) | 2008-11-20 |
| US20070009898A1 (en) | 2007-01-11 |
| DE60228132D1 (de) | 2008-09-18 |
| US20050092910A1 (en) | 2005-05-05 |
| JP2008076403A (ja) | 2008-04-03 |
| DE60211744T2 (de) | 2006-11-02 |
| DE60211744T3 (de) | 2010-07-01 |
| CA2465297A1 (en) | 2003-07-03 |
| CA2465297C (en) | 2011-02-15 |
| US20080135744A1 (en) | 2008-06-12 |
| GB2385918A (en) | 2003-09-03 |
| JP4654230B2 (ja) | 2011-03-16 |
| GB0228653D0 (en) | 2003-01-15 |
| GB2385918B (en) | 2004-05-26 |
| EP1456667B2 (de) | 2010-01-20 |
| WO2003054549A3 (en) | 2003-10-16 |
| US20080142696A1 (en) | 2008-06-19 |
| US8030089B2 (en) | 2011-10-04 |
| JP4767496B2 (ja) | 2011-09-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60228132D1 (de) | Massenspektormetrie-Verfahren | |
| WO2001011354A3 (en) | Methods for characterizing, classifying, and identifying unknowns in samples | |
| DE50210457D1 (de) | Vorrichtung zur referenzierung von fluoreszenzsignalen | |
| ATE357663T1 (de) | Teilchenförmiges markierungsmittel verwendendes analytassay | |
| PT100724A (pt) | Processo de determinacao da quantidade de grupos tiol ligados em proteinas e conjunto para a deteccao de estados isquemicos | |
| WO2003073817A3 (en) | Rapid and sensitive detection of cells and viruses | |
| WO2004113896A3 (en) | System and method for analysis of a biological fluid by the use electrical means | |
| IL124322A0 (en) | Detection of an entity in a sample | |
| AU2001287189A1 (en) | Detecting polymers and polymer fragments | |
| WO2004101769A3 (en) | Proteins, sensors, and methods of characterizing analytes using the same | |
| DE69401717D1 (de) | Verfahren zur Aktivierung von polyanionischen,fluoreszierenden Farbstoffen in schwach dielektrischen Medien mit quaternären Oniumverbindungen | |
| EP1415152A4 (de) | Verfahren, vorrichtungen und computerprogramme zum verifizieren der integrität einer sonde | |
| WO2004077057A8 (en) | Standard for immunohistochemistry, immunocytochemistry and molecular cytogenetics | |
| ATE318930T1 (de) | Nukleinsäuresonden zur detektion von candida- spezies | |
| ATE384139T1 (de) | Multi-test-analyse von echzeit- nukleinsäureamplifikationen | |
| EP1647825A3 (de) | Massenspektrometrieverfahren | |
| AU2001283901A1 (en) | Competitive assay method | |
| WO2001084161A3 (en) | Process for the measurement of non-transferrin bound iron | |
| AU4651689A (en) | Method and apparatus for identifying causes of repeatability problems in near infrared analytical instruments | |
| WO2002057743A3 (en) | Methods of analyzing and sorting one or more analytes | |
| WO2005056814A3 (en) | Methods and systems for analyzing and determining ligand-residue interaction | |
| TW200502399A (en) | Recombinant virus and use thereof and method of detecting an analyte in a sample and kit thereof | |
| WO2004016802A3 (en) | Methods and apparatus for preparing and assaying biological samples to determine protein concentration | |
| DE59910326D1 (de) | Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren | |
| ATE305980T1 (de) | Verwendung von abfangsonden beim nachweis von nukleinsäuren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |