ATE396734T1 - Mittel für intravitreale verabreichung zur behandlung oder vorbeugung von augenerkrankungen - Google Patents
Mittel für intravitreale verabreichung zur behandlung oder vorbeugung von augenerkrankungenInfo
- Publication number
- ATE396734T1 ATE396734T1 AT00916034T AT00916034T ATE396734T1 AT E396734 T1 ATE396734 T1 AT E396734T1 AT 00916034 T AT00916034 T AT 00916034T AT 00916034 T AT00916034 T AT 00916034T AT E396734 T1 ATE396734 T1 AT E396734T1
- Authority
- AT
- Austria
- Prior art keywords
- urea
- eye
- derivatives
- prevention
- agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12250399P | 1999-03-02 | 1999-03-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE396734T1 true ATE396734T1 (de) | 2008-06-15 |
Family
ID=22403079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00916034T ATE396734T1 (de) | 1999-03-02 | 2000-03-02 | Mittel für intravitreale verabreichung zur behandlung oder vorbeugung von augenerkrankungen |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1165095B1 (de) |
JP (2) | JP2002538125A (de) |
KR (1) | KR20010108296A (de) |
CN (2) | CN101711737A (de) |
AT (1) | ATE396734T1 (de) |
AU (2) | AU780299B2 (de) |
BG (1) | BG105867A (de) |
BR (1) | BR0008674A (de) |
CA (1) | CA2366050C (de) |
DE (1) | DE60039043D1 (de) |
ES (1) | ES2307498T3 (de) |
IL (2) | IL145226A0 (de) |
MX (1) | MXPA01008729A (de) |
NZ (1) | NZ513836A (de) |
RU (1) | RU2286157C2 (de) |
WO (1) | WO2000051620A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7977385B2 (en) | 2000-03-02 | 2011-07-12 | Numoda Biotechnologies, Inc. | Agents for corneal or intrastromal administration to treat or prevent disorders of the eye |
US20030199574A1 (en) | 2000-03-02 | 2003-10-23 | Vitreo-Retinal Technologies, Inc. | Treatment of ophthalmic disorders using urea and urea derivatives |
WO2003007798A2 (en) * | 2001-07-20 | 2003-01-30 | Iomed, Inc. | Ophthalmic use of 5 fluorourcil |
JP2004537551A (ja) * | 2001-07-20 | 2004-12-16 | イオメド インコーポレイテッド | メトトレキサートに基づく薬剤を投与することによって腫瘍性、血管原性、繊維芽細胞性及び/又は免疫抑制性眼球異常を治療する方法及びメトトレキサートに基づく薬剤を送達するための眼球イオン導入装置。 |
EP1480678B1 (de) * | 2002-02-13 | 2009-04-15 | Vitreo-Retinal Technologies, Inc. | Behandlung von augenkrankheiten mit harnstoff und harnstoffderivaten |
JP2005522464A (ja) * | 2002-03-14 | 2005-07-28 | ビトレオ−レチナール テクノロジーズ インコーポレイテッド | 眼の障害の治療または予防のために角膜または実質内に投与する薬剤 |
MXJL02000046A (es) * | 2002-12-13 | 2004-06-24 | Jimenez Bayardo Arturo | Solucion inyectable intravitrea para el tratamiento de hemorragias vitreas. |
CN101385697B (zh) * | 2008-10-30 | 2012-10-03 | 中国科学院上海药物研究所 | 氟比洛芬酯眼用纳米乳-原位凝胶制剂及其制备方法 |
RU2497498C2 (ru) * | 2012-02-14 | 2013-11-10 | Константин Николаевич Руссков | Фармацевтическая композиция для профилактики пролиферативной клеточной реакции "митомицин-о" |
AU2013201465B2 (en) * | 2012-10-24 | 2016-03-03 | Rayner Surgical (Ireland) Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
CN103393631B (zh) * | 2013-08-22 | 2015-04-08 | 北京蓝丹医药科技有限公司 | 一种氟比洛芬酯药物组合物 |
WO2015138391A1 (en) * | 2014-03-11 | 2015-09-17 | Rhee Douglas J | Methods of treating glaucoma using amp-activated protein kinase (ampk) activators |
TWI809304B (zh) | 2014-12-01 | 2023-07-21 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
PL3331517T3 (pl) | 2015-08-06 | 2020-06-29 | Centre Hospitalier National D'ophtalmologie Quinze-Vingts | Zastosowanie hydroksymocznika w celu zapobiegania brakowi perfuzji w siatkówce |
WO2017153567A1 (en) | 2016-03-10 | 2017-09-14 | Thrombogenics Nv | Posterior ocular fibrosis inhibition by antagonizing placental growth factor |
IL264842B (en) * | 2016-08-18 | 2022-08-01 | Troy Bremer | Delivery of urea to macular and retinal cells using liposome constructs |
EP3621603A4 (de) * | 2017-05-08 | 2021-01-20 | Meharry Medical College | Hydroxyharnstoff zur verbesserung von spermazellen |
GB2573784B (en) * | 2018-05-17 | 2020-10-07 | Nova Bio Pharma Product Dev Ltd | A stable aqueous hydroxycarbamide solution |
CN108721327A (zh) * | 2018-08-24 | 2018-11-02 | 苏州药明康德新药开发股份有限公司 | 实验动物视网膜色素变性试验模型的制备方法 |
MX2021009525A (es) * | 2019-02-08 | 2021-09-08 | Ohio State Innovation Foundation | Sustitutos vitreos de liberacion de antioxidante y usos de los mismos. |
JP2022146830A (ja) * | 2021-03-22 | 2022-10-05 | 均 石井 | 網膜剥離治療薬。 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0244178A3 (de) * | 1986-04-28 | 1989-02-08 | Iolab, Inc | Intraokuläre Mittel und Verfahren zu deren Verwendung |
CA1328614C (en) * | 1987-09-11 | 1994-04-19 | Cherng-Chyi Roger Fu | Preservative system for ophthalmics formulations |
US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
US5470881A (en) * | 1993-09-09 | 1995-11-28 | West Virginia University Research Corporation | Urea ophthalmic ointment and solution |
US5441984A (en) * | 1994-01-06 | 1995-08-15 | Eli Lilly And Company | Urea, thiourea and guanidine derivatives |
CA2201134A1 (en) * | 1994-10-10 | 1996-04-18 | Alfred Sallmann | Ophthalmic and aural compositions containing diclofenac potassium |
US5891084A (en) * | 1994-12-27 | 1999-04-06 | Lee; Vincent W. | Multiple chamber catheter delivery system |
US5554187A (en) * | 1995-08-18 | 1996-09-10 | Rizzo, Iii; Joseph | Medication dispensing intra-ocular lens system |
-
2000
- 2000-03-02 MX MXPA01008729A patent/MXPA01008729A/es active IP Right Grant
- 2000-03-02 CN CN200910222821A patent/CN101711737A/zh active Pending
- 2000-03-02 AU AU37201/00A patent/AU780299B2/en not_active Expired
- 2000-03-02 AT AT00916034T patent/ATE396734T1/de not_active IP Right Cessation
- 2000-03-02 NZ NZ513836A patent/NZ513836A/xx not_active IP Right Cessation
- 2000-03-02 RU RU2001124272/14A patent/RU2286157C2/ru active
- 2000-03-02 CA CA2366050A patent/CA2366050C/en not_active Expired - Lifetime
- 2000-03-02 WO PCT/US2000/005587 patent/WO2000051620A1/en active IP Right Grant
- 2000-03-02 DE DE60039043T patent/DE60039043D1/de not_active Expired - Fee Related
- 2000-03-02 BR BR0008674-6A patent/BR0008674A/pt not_active Application Discontinuation
- 2000-03-02 KR KR1020017011153A patent/KR20010108296A/ko not_active Application Discontinuation
- 2000-03-02 CN CN00807107A patent/CN1377272A/zh active Pending
- 2000-03-02 IL IL14522600A patent/IL145226A0/xx active IP Right Grant
- 2000-03-02 JP JP2000602088A patent/JP2002538125A/ja active Pending
- 2000-03-02 ES ES00916034T patent/ES2307498T3/es not_active Expired - Lifetime
- 2000-03-02 EP EP00916034A patent/EP1165095B1/de not_active Expired - Lifetime
-
2001
- 2001-09-01 BG BG105867A patent/BG105867A/xx unknown
- 2001-09-02 IL IL145226A patent/IL145226A/en not_active IP Right Cessation
-
2005
- 2005-06-14 AU AU2005202579A patent/AU2005202579A1/en not_active Abandoned
-
2010
- 2010-12-03 JP JP2010270694A patent/JP5428101B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2307498T3 (es) | 2008-12-01 |
EP1165095A4 (de) | 2004-12-15 |
AU2005202579A1 (en) | 2005-07-07 |
EP1165095A1 (de) | 2002-01-02 |
JP2011088911A (ja) | 2011-05-06 |
IL145226A (en) | 2007-07-04 |
DE60039043D1 (de) | 2008-07-10 |
JP2002538125A (ja) | 2002-11-12 |
BG105867A (en) | 2002-04-30 |
IL145226A0 (en) | 2002-06-30 |
MXPA01008729A (es) | 2003-06-24 |
BR0008674A (pt) | 2002-02-13 |
RU2286157C2 (ru) | 2006-10-27 |
WO2000051620A1 (en) | 2000-09-08 |
CN101711737A (zh) | 2010-05-26 |
KR20010108296A (ko) | 2001-12-07 |
NZ513836A (en) | 2004-01-30 |
CA2366050A1 (en) | 2000-09-08 |
AU780299B2 (en) | 2005-03-17 |
JP5428101B2 (ja) | 2014-02-26 |
CN1377272A (zh) | 2002-10-30 |
AU3720100A (en) | 2000-09-21 |
CA2366050C (en) | 2011-05-24 |
EP1165095B1 (de) | 2008-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |