ATE390632T1 - Verfahren und gerät zum nachweis des gesamten proteingehaltes bei niedrigen ph-werten - Google Patents
Verfahren und gerät zum nachweis des gesamten proteingehaltes bei niedrigen ph-wertenInfo
- Publication number
- ATE390632T1 ATE390632T1 AT02738447T AT02738447T ATE390632T1 AT E390632 T1 ATE390632 T1 AT E390632T1 AT 02738447 T AT02738447 T AT 02738447T AT 02738447 T AT02738447 T AT 02738447T AT E390632 T1 ATE390632 T1 AT E390632T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- dye
- buffer
- test fluid
- range
- Prior art date
Links
- 235000018102 proteins Nutrition 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 239000012530 fluid Substances 0.000 abstract 4
- 238000003556 assay Methods 0.000 abstract 3
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
- MLIREBYILWEBDM-UHFFFAOYSA-N cyanoacetic acid Chemical compound OC(=O)CC#N MLIREBYILWEBDM-UHFFFAOYSA-N 0.000 abstract 2
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 abstract 2
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical group NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 abstract 1
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 abstract 1
- 108010077895 Sarcosine Proteins 0.000 abstract 1
- 230000002745 absorbent Effects 0.000 abstract 1
- 239000002250 absorbent Substances 0.000 abstract 1
- HNEGQIOMVPPMNR-IHWYPQMZSA-N citraconic acid Chemical compound OC(=O)C(/C)=C\C(O)=O HNEGQIOMVPPMNR-IHWYPQMZSA-N 0.000 abstract 1
- 229940018557 citraconic acid Drugs 0.000 abstract 1
- 229960002173 citrulline Drugs 0.000 abstract 1
- 235000013477 citrulline Nutrition 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- YACKEPLHDIMKIO-UHFFFAOYSA-N methylphosphonic acid Chemical compound CP(O)(O)=O YACKEPLHDIMKIO-UHFFFAOYSA-N 0.000 abstract 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 abstract 1
- 229940081974 saccharin Drugs 0.000 abstract 1
- 235000019204 saccharin Nutrition 0.000 abstract 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 abstract 1
- 229940043230 sarcosine Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6827—Total protein determination, e.g. albumin in urine
- G01N33/6839—Total protein determination, e.g. albumin in urine involving dyes, e.g. Coomassie blue, bromcresol green
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30010401P | 2001-06-25 | 2001-06-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE390632T1 true ATE390632T1 (de) | 2008-04-15 |
Family
ID=23157725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02738447T ATE390632T1 (de) | 2001-06-25 | 2002-06-21 | Verfahren und gerät zum nachweis des gesamten proteingehaltes bei niedrigen ph-werten |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6815210B1 (de) |
| EP (1) | EP1405080B1 (de) |
| JP (1) | JP3843270B2 (de) |
| CN (1) | CN1520517A (de) |
| AT (1) | ATE390632T1 (de) |
| AU (1) | AU2002311527A1 (de) |
| CA (1) | CA2451611A1 (de) |
| DE (1) | DE60225802T2 (de) |
| ES (1) | ES2305255T3 (de) |
| NO (1) | NO20035502D0 (de) |
| WO (1) | WO2003001213A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7563621B2 (en) * | 2002-03-05 | 2009-07-21 | Siemens Healhcare Diagnostics Inc | Absorbing organic reagents into diagnostic test devices by formation of amine salt complexes |
| JP4489590B2 (ja) * | 2002-08-09 | 2010-06-23 | アークレイ株式会社 | 蛋白質測定用試験片およびその製造方法 |
| EP1536233B1 (de) * | 2002-08-09 | 2010-10-13 | ARKRAY, Inc. | Teststück fur proteinassay |
| US8460877B2 (en) | 2004-01-23 | 2013-06-11 | Arkray, Inc. | Method of protein measurement |
| US20060084175A1 (en) * | 2004-10-19 | 2006-04-20 | Wayne Comper | Colorimetric strip containing coomassie blue for semi-quantitation of albumin |
| GB2426334A (en) * | 2005-05-20 | 2006-11-22 | Orion Diagnostica Oy | Application of a reagent to a matrix material |
| EP2198299A4 (de) * | 2007-10-18 | 2010-09-29 | Momtec Life Ltd | Diagnosevorrichtung zur identifikation von membranenrissen während einer schwangerschaft |
| KR100967620B1 (ko) * | 2008-01-17 | 2010-07-05 | 전남대학교산학협력단 | 에오신 ｙ를 함유하는 유기염료 조성물을 이용한폴리아크릴아미드 겔상의 단백질 검출방법 및 이를 위한유기염료 조성물 |
| US7745153B2 (en) * | 2008-02-06 | 2010-06-29 | Pierce Biotechnology, Inc. | Pyrocatechol violet-metal protein assay |
| JP5542888B2 (ja) * | 2011-10-17 | 2014-07-09 | アークレイ株式会社 | 蛋白質濃度評価方法、分析用具、及び分析装置 |
| CN102617410B (zh) * | 2012-03-15 | 2013-11-06 | 长春万成生物电子工程有限公司 | 一种3,4,5,6-四卤代酚磺酞的纯化方法 |
| CN102680701A (zh) * | 2012-04-27 | 2012-09-19 | 嘉兴九七九生物技术有限公司 | 一种尿蛋白液体定量检测试剂及方法 |
| WO2014118543A2 (en) * | 2013-01-30 | 2014-08-07 | Vantix Holdings Limited | Electrochemical total protein detection system |
| CN104777148B (zh) * | 2015-04-17 | 2018-05-01 | 华东理工大学 | 一种快速检测牛奶中总蛋白的方法 |
| EP3328538B1 (de) | 2015-08-28 | 2024-06-12 | Serionix, Inc. | Gasfilter für basische verunreinigungen |
| CN105548171B (zh) * | 2016-01-11 | 2018-05-08 | 吉林基蛋生物科技有限公司 | 一种脑脊液和尿蛋白液体单试剂及其制备方法 |
| US11119094B2 (en) * | 2017-09-27 | 2021-09-14 | Cd Diagnostics, Inc. | Aqueous citrate-buffered metal solutions |
| CN108120714B (zh) * | 2017-12-20 | 2020-11-27 | 吉林省汇酉生物技术股份有限公司 | 一种检测尿液尿微量白蛋白的试剂及其应用 |
| FR3111553A1 (fr) * | 2020-06-22 | 2021-12-24 | L'oreal | Procédé de coloration des fibres kératiniques mettant en œuvre un colorant direct et un sel de saccharinate et composition les comprenant |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3485587A (en) * | 1956-02-29 | 1969-12-23 | Miles Lab | Protein indicator |
| US3438737A (en) * | 1965-10-01 | 1969-04-15 | Miles Lab | Protein test composition,device and method |
| US5087575A (en) * | 1988-06-06 | 1992-02-11 | Miles Inc. | Composition for determining trace amount of protein |
| US5049358A (en) * | 1988-09-30 | 1991-09-17 | Miles Inc. | Composition and test device for assaying for proteins |
| US5077222A (en) * | 1988-09-30 | 1991-12-31 | Miles Inc. | Method for assaying for proteins using a dual indicator reagent composition |
| DE69213826T2 (de) * | 1991-06-06 | 1997-01-30 | Bayer Ag | Teststreifen mit Merocyanin und Nitro- oder Nitroso-substituierten polyhalogenierten Phenolsulfonphthaleinen als Protein-Indikatoren |
| JP3090503B2 (ja) | 1991-06-07 | 2000-09-25 | 国際試薬株式会社 | 蛋白質の測定法 |
| US5326707A (en) * | 1991-11-29 | 1994-07-05 | Miles Inc. | Composition and device for urinary protein assay and method of using the same |
| US5399498A (en) * | 1993-12-17 | 1995-03-21 | Miles Inc. | Reduction of background interferences in the molybdate-dye protein assay |
| US5424215A (en) * | 1994-02-07 | 1995-06-13 | Miles Inc. | Assay for the determination of protein in a biological sample |
| US5424125A (en) * | 1994-04-11 | 1995-06-13 | Shakespeare Company | Monofilaments from polymer blends and fabrics thereof |
| US5593895A (en) * | 1995-04-27 | 1997-01-14 | Bayer Corporation | Method for the detection of protein in urine |
| US5716851A (en) * | 1996-01-16 | 1998-02-10 | Bayer Corporation | Glass/cellulose as protein reagent |
| US5750405A (en) * | 1996-03-01 | 1998-05-12 | Bayer Corporation | Method for the detection for protein |
| CA2236350C (en) | 1997-05-06 | 2007-05-15 | Thomas Arter | Dry analytical elements for the determination of protein |
| US5908787A (en) * | 1997-09-23 | 1999-06-01 | Bayer Corporation | Total protein detection method |
-
2002
- 2002-06-21 AU AU2002311527A patent/AU2002311527A1/en not_active Abandoned
- 2002-06-21 CN CNA028127587A patent/CN1520517A/zh active Pending
- 2002-06-21 EP EP02738447A patent/EP1405080B1/de not_active Expired - Lifetime
- 2002-06-21 JP JP2003507557A patent/JP3843270B2/ja not_active Expired - Lifetime
- 2002-06-21 AT AT02738447T patent/ATE390632T1/de not_active IP Right Cessation
- 2002-06-21 US US10/480,314 patent/US6815210B1/en not_active Expired - Lifetime
- 2002-06-21 WO PCT/IB2002/002321 patent/WO2003001213A2/en active IP Right Grant
- 2002-06-21 ES ES02738447T patent/ES2305255T3/es not_active Expired - Lifetime
- 2002-06-21 DE DE60225802T patent/DE60225802T2/de not_active Expired - Lifetime
- 2002-06-21 CA CA002451611A patent/CA2451611A1/en not_active Abandoned
-
2003
- 2003-12-10 NO NO20035502A patent/NO20035502D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60225802D1 (de) | 2008-05-08 |
| WO2003001213A2 (en) | 2003-01-03 |
| EP1405080A2 (de) | 2004-04-07 |
| DE60225802T2 (de) | 2009-04-16 |
| AU2002311527A1 (en) | 2003-01-08 |
| JP3843270B2 (ja) | 2006-11-08 |
| ES2305255T3 (es) | 2008-11-01 |
| EP1405080B1 (de) | 2008-03-26 |
| NO20035502D0 (no) | 2003-12-10 |
| CA2451611A1 (en) | 2003-01-03 |
| CN1520517A (zh) | 2004-08-11 |
| WO2003001213A9 (en) | 2004-03-04 |
| US6815210B1 (en) | 2004-11-09 |
| US20040214339A1 (en) | 2004-10-28 |
| WO2003001213A3 (en) | 2003-08-28 |
| JP2005503542A (ja) | 2005-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |