ATE375975T1 - Aliphatische aminosäure und aminophosphonsäure, aminonitrile und aminotetrazole als zellulares rettungsmittel - Google Patents

Aliphatische aminosäure und aminophosphonsäure, aminonitrile und aminotetrazole als zellulares rettungsmittel

Info

Publication number
ATE375975T1
ATE375975T1 AT99908728T AT99908728T ATE375975T1 AT E375975 T1 ATE375975 T1 AT E375975T1 AT 99908728 T AT99908728 T AT 99908728T AT 99908728 T AT99908728 T AT 99908728T AT E375975 T1 ATE375975 T1 AT E375975T1
Authority
AT
Austria
Prior art keywords
aminonitrils
aminotetrazoles
carbon atoms
acid
aliphatic amino
Prior art date
Application number
AT99908728T
Other languages
English (en)
Inventor
I Paterson
Lillian Dyck
Bruce Davis
Ya-Dong Liu
David Durden
Alan Boulton
Original Assignee
Univ Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Saskatchewan filed Critical Univ Saskatchewan
Application granted granted Critical
Publication of ATE375975T1 publication Critical patent/ATE375975T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/25—Aminoacetonitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Steroid Compounds (AREA)
AT99908728T 1998-03-26 1999-03-25 Aliphatische aminosäure und aminophosphonsäure, aminonitrile und aminotetrazole als zellulares rettungsmittel ATE375975T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7948898P 1998-03-26 1998-03-26
US7948998P 1998-03-26 1998-03-26

Publications (1)

Publication Number Publication Date
ATE375975T1 true ATE375975T1 (de) 2007-11-15

Family

ID=26762066

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99908728T ATE375975T1 (de) 1998-03-26 1999-03-25 Aliphatische aminosäure und aminophosphonsäure, aminonitrile und aminotetrazole als zellulares rettungsmittel

Country Status (15)

Country Link
EP (1) EP1064254B1 (de)
JP (1) JP2002507591A (de)
CN (1) CN1213999C (de)
AT (1) ATE375975T1 (de)
AU (1) AU767098B2 (de)
BR (1) BR9909103A (de)
CA (1) CA2325943A1 (de)
DE (1) DE69937340T2 (de)
EA (1) EA003677B1 (de)
ES (1) ES2296383T3 (de)
NO (1) NO20004774D0 (de)
PL (1) PL343531A1 (de)
SK (1) SK16662000A3 (de)
TR (1) TR200002756T2 (de)
WO (1) WO1999048858A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230065740A1 (en) 2018-12-28 2023-03-02 Spv Therapeutics Inc. Cyclin-dependent kinase inhibitors

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3113026A (en) * 1959-01-19 1963-12-03 Gen Aniline & Film Corp Polyvinyl alcohol photographic silver halide emulsions
DE1567221A1 (de) * 1965-06-01 1970-04-16 Berlin Chemie Veb Systemische Fungizide
BE758165A (fr) * 1969-10-28 1971-04-28 Cilag Chemie Adamantylurees et procedes pour les preparer
IL45563A0 (en) * 1973-09-05 1974-11-29 Sumitomo Chemical Co N-substituted aminonitrile derivatives,their preparation and their use as fungicides
US3991208A (en) * 1973-12-28 1976-11-09 Millmaster Onyx Corporation Amphoteric surface-active agents
DE2555769C3 (de) * 1975-12-11 1980-01-03 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von an der Aminogruppe aliphatisch substituierten Glycinnitrilen
DE3010599A1 (de) * 1979-03-22 1980-10-09 Continental Pharma Derivate von glycinamid, deren herstellung und verwendung
US4548726A (en) * 1984-11-16 1985-10-22 Texaco Inc. Water base hydraulic fluid
KR930005009B1 (ko) * 1990-03-27 1993-06-11 한국과학기술연구원 N-알킬치환아미노메틸포스폰산 유도체의 제조방법
US5169868A (en) * 1991-03-01 1992-12-08 University Of Saskatchewan Aliphatic propargylamines as specific mao-b inhibitors
JPH0856655A (ja) * 1994-08-16 1996-03-05 Frontier:Kk 細胞致死剤および細胞死抑制剤
CZ294348B6 (cs) * 1996-05-31 2004-12-15 Allelix Neuroscience Inc. Substituovaný derivát glycinu a farmaceutický prostředek s jeho obsahem

Also Published As

Publication number Publication date
DE69937340D1 (de) 2007-11-29
NO20004774L (no) 2000-09-25
PL343531A1 (en) 2001-08-27
CN1299342A (zh) 2001-06-13
EP1064254B1 (de) 2007-10-17
NO20004774D0 (no) 2000-09-25
DE69937340T2 (de) 2008-07-17
JP2002507591A (ja) 2002-03-12
SK16662000A3 (sk) 2001-05-10
WO1999048858A2 (en) 1999-09-30
ES2296383T3 (es) 2008-04-16
EA003677B1 (ru) 2003-08-28
EP1064254A2 (de) 2001-01-03
AU2824099A (en) 1999-10-18
EA200000987A1 (ru) 2001-06-25
CN1213999C (zh) 2005-08-10
TR200002756T2 (tr) 2000-12-21
WO1999048858A3 (en) 2000-01-20
CA2325943A1 (en) 1999-09-30
AU767098B2 (en) 2003-10-30
BR9909103A (pt) 2001-10-16

Similar Documents

Publication Publication Date Title
ATE317691T1 (de) Benzochinonderivate enthaltende hemmer von nf-kb
PT984955E (pt) 2-(2,6-dioxopiperidin-3-il) ftalimidas e 1-oxoisoindolinas substituidas e metodo de reducao dos niveis de tnfalfa
FI965020A0 (fi) Uusia yhdisteitä, menetelmiä niiden valmistamiseksi ja kasvaintenvastaisia aineita
DK1312359T3 (da) Anvendelse af 1,3-propandiolforbindelser
CO5200791A1 (es) Acidos 3-propil gamma-aminobutiricos mono- y disustituidos
GR3027694T3 (en) Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists.
TW343975B (en) New phospholipid derivatives of phosphonocarboxylic acids, the production thereof as well as their use as antiviral pharmaceutical agents
ATE375975T1 (de) Aliphatische aminosäure und aminophosphonsäure, aminonitrile und aminotetrazole als zellulares rettungsmittel
BG105123A (en) Tetrahydroquinaline derivatives as glycine antagonists
FI845102L (fi) Imidazo/1,2-c/pyrimidiner.
NO20000198L (no) Pyrazinderivater, deres fremstilling samt medikamenter inneholdende forbindelsene
KR890002208A (ko) 아미노 메틸렌 포스포노 알킬포스피네이트의 합성방법
DE60025171D1 (de) 1-acyl-7-nitroindolin derivate, deren herstellung und deren verwendung als photospaltbare vorstufen
WO2003075928A3 (en) Stable pharmaceutical compositions
FR2795727B1 (fr) Nouveaux derives benzodioxanne imidazolines fluores, leur preparation et leurs applications en therapeutique
WO1993004059A1 (fr) Derive de 4-acylaminoimidazole
ATE251632T1 (de) Phosphonsäure-diester-derivate
DE69909811D1 (de) Substituierte isoxazolylthiophenverbindungen
MX9302970A (es) Analogos de acido l-glutamico y gaba para tratamiento anti-ataque.
TW349949B (en) New imidazole derivatives, preparation process, intermediates obtained, use as medicaments, pharmaceutical compositions and new use
ECSP951403A (es) Compuestos heterociclicos y fenilo
DE69707793D1 (de) Alkynylaminosäure Derivate und ihre Verwendung als pharmazeutische Verbindungen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties