ATE245643T1 - Substituierte isoxazolylthiophenverbindungen - Google Patents
Substituierte isoxazolylthiophenverbindungenInfo
- Publication number
- ATE245643T1 ATE245643T1 AT99969721T AT99969721T ATE245643T1 AT E245643 T1 ATE245643 T1 AT E245643T1 AT 99969721 T AT99969721 T AT 99969721T AT 99969721 T AT99969721 T AT 99969721T AT E245643 T1 ATE245643 T1 AT E245643T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- alkyl
- isoxazolylthiophene
- substituted
- substituted isoxazolylthiophene
- Prior art date
Links
- IWMABJZZIWFKGH-UHFFFAOYSA-N 3-thiophen-2-yl-1,2-oxazole Chemical class C1=CSC(C2=NOC=C2)=C1 IWMABJZZIWFKGH-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 208000020084 Bone disease Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27628898 | 1998-09-30 | ||
| PCT/JP1999/005315 WO2000018765A1 (en) | 1998-09-30 | 1999-09-29 | Substituted isoxazolylthiophene compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE245643T1 true ATE245643T1 (de) | 2003-08-15 |
Family
ID=17567370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99969721T ATE245643T1 (de) | 1998-09-30 | 1999-09-29 | Substituierte isoxazolylthiophenverbindungen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6355663B1 (de) |
| EP (1) | EP1120415B1 (de) |
| KR (1) | KR20010075447A (de) |
| CN (1) | CN1117091C (de) |
| AT (1) | ATE245643T1 (de) |
| AU (1) | AU755425B2 (de) |
| CA (1) | CA2343194A1 (de) |
| DE (1) | DE69909811T2 (de) |
| DK (1) | DK1120415T3 (de) |
| ES (1) | ES2203246T3 (de) |
| PT (1) | PT1120415E (de) |
| WO (1) | WO2000018765A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002079199A1 (en) * | 2001-03-29 | 2002-10-10 | Takeda Chemical Industries, Ltd. | Thiophene derivatives and use thereof |
| WO2001089521A1 (en) * | 2000-05-23 | 2001-11-29 | Takeda Chemical Industries, Ltd. | Medicinal compositions containing thiophene derivatives |
| JO2355B1 (en) | 2003-04-15 | 2006-12-12 | ميرك شارب اند دوم كوربوريشن | Hereditary calcitonin polypeptide receptor antagonists |
| US20070060573A1 (en) * | 2005-08-10 | 2007-03-15 | Lars Wortmann | Acyltryptophanols |
| WO2019010467A2 (en) * | 2017-07-07 | 2019-01-10 | Armis Biophama, Inc. | OXIDANT COMPOSITIONS AND METHODS FOR STIMULATING OSTEOBLAST GROWTH AND USE IN DENTAL COATINGS AND BONE JAR INCREASE |
| CN111018829B (zh) * | 2018-10-09 | 2022-10-04 | 中国科学院大连化学物理研究所 | 4-烷硫基多取代噻吩衍生物及其合成 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI943948L (fi) * | 1992-12-28 | 1994-08-26 | Eisai Co Ltd | Heterosykliset hiilihappojohdannaiset |
| JPH09291082A (ja) * | 1996-02-27 | 1997-11-11 | Sankyo Co Ltd | イソキサゾール誘導体 |
| CA2263583A1 (en) * | 1996-09-06 | 1998-03-12 | Shigehisa Taketomi | Condensed 4,5,6,7-tetrahydrobenzo¬c|thiophenes as enhancer for cell differentiation induction factor action |
| AU5283399A (en) * | 1998-07-15 | 2000-02-07 | Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Method for transferring solder to a device and/or testing the device |
-
1999
- 1999-09-29 DK DK99969721T patent/DK1120415T3/da active
- 1999-09-29 WO PCT/JP1999/005315 patent/WO2000018765A1/ja not_active Ceased
- 1999-09-29 CN CN99811631A patent/CN1117091C/zh not_active Expired - Fee Related
- 1999-09-29 ES ES99969721T patent/ES2203246T3/es not_active Expired - Lifetime
- 1999-09-29 EP EP99969721A patent/EP1120415B1/de not_active Expired - Lifetime
- 1999-09-29 DE DE69909811T patent/DE69909811T2/de not_active Expired - Fee Related
- 1999-09-29 AU AU59978/99A patent/AU755425B2/en not_active Ceased
- 1999-09-29 AT AT99969721T patent/ATE245643T1/de not_active IP Right Cessation
- 1999-09-29 CA CA002343194A patent/CA2343194A1/en not_active Abandoned
- 1999-09-29 US US09/786,119 patent/US6355663B1/en not_active Expired - Fee Related
- 1999-09-29 PT PT99969721T patent/PT1120415E/pt unknown
- 1999-09-29 KR KR1020017004000A patent/KR20010075447A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1120415A1 (de) | 2001-08-01 |
| AU5997899A (en) | 2000-04-17 |
| CN1321156A (zh) | 2001-11-07 |
| CA2343194A1 (en) | 2000-04-06 |
| US6355663B1 (en) | 2002-03-12 |
| AU755425B2 (en) | 2002-12-12 |
| WO2000018765A1 (en) | 2000-04-06 |
| DE69909811T2 (de) | 2004-01-29 |
| PT1120415E (pt) | 2003-12-31 |
| CN1117091C (zh) | 2003-08-06 |
| EP1120415A4 (de) | 2002-01-23 |
| DK1120415T3 (da) | 2003-11-03 |
| KR20010075447A (ko) | 2001-08-09 |
| DE69909811D1 (de) | 2003-08-28 |
| ES2203246T3 (es) | 2004-04-01 |
| EP1120415B1 (de) | 2003-07-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE270103T1 (de) | Aminophenoxyessigsäure derivate als neuroschützende mittel | |
| DE60015927D1 (en) | Phenylharnstoff und phenylthioharnstoffderivate | |
| DE69922216D1 (de) | Porphyrin derivate, ihre verwendung in der photodynamischen therapie und diese enthaltende medizinische geräte | |
| DE3781716D1 (de) | Mittel zur ortsspezifischen alkylierung. | |
| DE69738245D1 (de) | 1,2-Diphenylpyrrol-Derivate, ihre Herstellung und therapeutische Verwendung | |
| ES2115163T3 (es) | Procedimiento para inhibir la proliferacion de celulas de musculos lisos y la restinosis. | |
| DK0756595T3 (da) | Substituerede 1,3-oxathiolaner med antivirale egenskaber | |
| TR200101499T1 (tr) | Azepinoindol türevleri, hazırlanmaları ve kullanımları. | |
| DE60005504D1 (de) | Chinolinderivate als mek enzym-inhibitoren | |
| EA200000614A1 (ru) | 2,3-замещенные соединения индола в качестве ингибиторов сох-2 | |
| EA200100983A1 (ru) | Производные 13-метилэритромицина | |
| DE69728544D1 (de) | Totalsynthese von acylfulvenen mit antitumorwirkung | |
| DE60234589D1 (de) | Substituierte 4h-chromene und analoga als aktivatoren von caspasen und induktoren von apoptose, und deren verwendung als antikrebsmittel | |
| ID26622A (id) | Senyawa-senyawa pengganti 2-benzylamino-2-phenyl-acetamide | |
| SE8503466D0 (sv) | Aminofenolforeningar | |
| DE69909811T2 (de) | Substituierte isoxazolylthiophenverbindungen | |
| ES2099180T3 (es) | Derivados del benzopirano y procedimientos para su preparacion. | |
| ES2193047T3 (es) | (3,4 dihydro-2h-benzo(1,4) oxazinilmetil)(3-(1h-indol-3-il)-alquil)-aminas. | |
| TR200003877T2 (tr) | İnsan CD23 üretiminin ve TNF salınmasının ihhibitörleri olan hiydroxamic acid türevleri | |
| ATE218138T1 (de) | N-substituierte azabicycloheptan-derivate, ihre herstellung und verwendung | |
| KR970706280A (ko) | 5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists) | |
| BG106846A (en) | Novel heteroaryl derivatives, their preparation and use | |
| DE69527854D1 (de) | Derivate substituierter amidinonaphthylester | |
| DE69827706D1 (de) | 5-(Heteroaryl)alkyl)-3-oxo-pyrido(1,2-a)benzimidazol-4-carboxamid (PBI) Derivate zur Behandlung von Störungen des zentralen Nervensystems | |
| EA200001157A3 (ru) | Новые замещенные производные (дигидро)бензоксазина и (дигидро)бензотиазина, способ их получения и содержащие их фармацевтические композиции |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1120415 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |