DE69909811T2 - Substituierte isoxazolylthiophenverbindungen - Google Patents
Substituierte isoxazolylthiophenverbindungen Download PDFInfo
- Publication number
- DE69909811T2 DE69909811T2 DE69909811T DE69909811T DE69909811T2 DE 69909811 T2 DE69909811 T2 DE 69909811T2 DE 69909811 T DE69909811 T DE 69909811T DE 69909811 T DE69909811 T DE 69909811T DE 69909811 T2 DE69909811 T2 DE 69909811T2
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- alkyl
- isoxazolylthiophene
- substituted
- substituted isoxazolylthiophene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- IWMABJZZIWFKGH-UHFFFAOYSA-N 3-thiophen-2-yl-1,2-oxazole Chemical class C1=CSC(C2=NOC=C2)=C1 IWMABJZZIWFKGH-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 208000020084 Bone disease Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27628898 | 1998-09-30 | ||
| PCT/JP1999/005315 WO2000018765A1 (fr) | 1998-09-30 | 1999-09-29 | Composes d'isoxazolylthiophene substitue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69909811D1 DE69909811D1 (de) | 2003-08-28 |
| DE69909811T2 true DE69909811T2 (de) | 2004-01-29 |
Family
ID=17567370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69909811T Expired - Fee Related DE69909811T2 (de) | 1998-09-30 | 1999-09-29 | Substituierte isoxazolylthiophenverbindungen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6355663B1 (de) |
| EP (1) | EP1120415B1 (de) |
| KR (1) | KR20010075447A (de) |
| CN (1) | CN1117091C (de) |
| AT (1) | ATE245643T1 (de) |
| AU (1) | AU755425B2 (de) |
| CA (1) | CA2343194A1 (de) |
| DE (1) | DE69909811T2 (de) |
| DK (1) | DK1120415T3 (de) |
| ES (1) | ES2203246T3 (de) |
| PT (1) | PT1120415E (de) |
| WO (1) | WO2000018765A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002079199A1 (fr) * | 2001-03-29 | 2002-10-10 | Takeda Chemical Industries, Ltd. | Derives de thiophene et leur utilisation |
| WO2001089521A1 (fr) * | 2000-05-23 | 2001-11-29 | Takeda Chemical Industries, Ltd. | Compositions medicinales contenant des derives du tiophene |
| JO2355B1 (en) | 2003-04-15 | 2006-12-12 | ميرك شارب اند دوم كوربوريشن | Hereditary calcitonin polypeptide receptor antagonists |
| US20070060573A1 (en) * | 2005-08-10 | 2007-03-15 | Lars Wortmann | Acyltryptophanols |
| EP3648689A4 (de) | 2017-07-07 | 2021-04-07 | Armis Biopharma, Inc. | Oxidative zusammensetzungen und verfahren zur stimulierung des wachstums von osteoblasten und verwendung in dentalbeschichtungen und kieferknochenverstärkung |
| CN111018829B (zh) * | 2018-10-09 | 2022-10-04 | 中国科学院大连化学物理研究所 | 4-烷硫基多取代噻吩衍生物及其合成 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0638071B1 (de) * | 1992-12-28 | 1997-04-09 | Eisai Co., Ltd. | Heterocyclische carbonsäure-derivate, die an rar rezeptoren binden können |
| JPH09291082A (ja) * | 1996-02-27 | 1997-11-11 | Sankyo Co Ltd | イソキサゾール誘導体 |
| AU4135397A (en) * | 1996-09-06 | 1998-03-26 | Takeda Chemical Industries Ltd. | Condensed 4,5,6,7-tetrahydrobenzo{c}thiophenes as enhancer for cell differentiation induction factor action |
| AU5283399A (en) * | 1998-07-15 | 2000-02-07 | Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. | Method for transferring solder to a device and/or testing the device |
-
1999
- 1999-09-29 AT AT99969721T patent/ATE245643T1/de not_active IP Right Cessation
- 1999-09-29 DK DK99969721T patent/DK1120415T3/da active
- 1999-09-29 CN CN99811631A patent/CN1117091C/zh not_active Expired - Fee Related
- 1999-09-29 ES ES99969721T patent/ES2203246T3/es not_active Expired - Lifetime
- 1999-09-29 EP EP99969721A patent/EP1120415B1/de not_active Expired - Lifetime
- 1999-09-29 WO PCT/JP1999/005315 patent/WO2000018765A1/ja not_active Application Discontinuation
- 1999-09-29 US US09/786,119 patent/US6355663B1/en not_active Expired - Fee Related
- 1999-09-29 KR KR1020017004000A patent/KR20010075447A/ko not_active Application Discontinuation
- 1999-09-29 PT PT99969721T patent/PT1120415E/pt unknown
- 1999-09-29 DE DE69909811T patent/DE69909811T2/de not_active Expired - Fee Related
- 1999-09-29 CA CA002343194A patent/CA2343194A1/en not_active Abandoned
- 1999-09-29 AU AU59978/99A patent/AU755425B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1120415A1 (de) | 2001-08-01 |
| EP1120415A4 (de) | 2002-01-23 |
| CA2343194A1 (en) | 2000-04-06 |
| ES2203246T3 (es) | 2004-04-01 |
| DE69909811D1 (de) | 2003-08-28 |
| AU755425B2 (en) | 2002-12-12 |
| WO2000018765A1 (fr) | 2000-04-06 |
| AU5997899A (en) | 2000-04-17 |
| CN1117091C (zh) | 2003-08-06 |
| KR20010075447A (ko) | 2001-08-09 |
| CN1321156A (zh) | 2001-11-07 |
| ATE245643T1 (de) | 2003-08-15 |
| DK1120415T3 (da) | 2003-11-03 |
| US6355663B1 (en) | 2002-03-12 |
| PT1120415E (pt) | 2003-12-31 |
| EP1120415B1 (de) | 2003-07-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |