ATE251632T1 - Phosphonsäure-diester-derivate - Google Patents
Phosphonsäure-diester-derivateInfo
- Publication number
- ATE251632T1 ATE251632T1 AT99917075T AT99917075T ATE251632T1 AT E251632 T1 ATE251632 T1 AT E251632T1 AT 99917075 T AT99917075 T AT 99917075T AT 99917075 T AT99917075 T AT 99917075T AT E251632 T1 ATE251632 T1 AT E251632T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- amino
- diester derivatives
- phosphonic acid
- acid diester
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
- C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11553698A JP4032193B2 (ja) | 1998-04-24 | 1998-04-24 | ホスホン酸ジエステル誘導体 |
| PCT/JP1999/002114 WO1999055713A1 (fr) | 1998-04-24 | 1999-04-21 | Derives de diester phosphonique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE251632T1 true ATE251632T1 (de) | 2003-10-15 |
Family
ID=14664971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99917075T ATE251632T1 (de) | 1998-04-24 | 1999-04-21 | Phosphonsäure-diester-derivate |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6468992B1 (de) |
| EP (1) | EP1074556B1 (de) |
| JP (1) | JP4032193B2 (de) |
| KR (1) | KR100753378B1 (de) |
| CN (1) | CN1177852C (de) |
| AT (1) | ATE251632T1 (de) |
| AU (1) | AU756940B2 (de) |
| CA (1) | CA2330111A1 (de) |
| DE (1) | DE69911946T2 (de) |
| NO (1) | NO20005328L (de) |
| TW (1) | TWI230711B (de) |
| WO (1) | WO1999055713A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL132315A0 (en) * | 1999-10-11 | 2001-03-19 | Yissum Res Dev Co | Compositions comprising oxophosphonate-based metalloproteinase inhibitors |
| US7956360B2 (en) * | 2004-06-03 | 2011-06-07 | The Regents Of The University Of California | Growth of planar reduced dislocation density M-plane gallium nitride by hydride vapor phase epitaxy |
| CN101490064B (zh) * | 2006-07-06 | 2012-10-10 | 百时美施贵宝公司 | 新颖葡萄糖激酶活化剂及其使用方法 |
| US7910747B2 (en) | 2006-07-06 | 2011-03-22 | Bristol-Myers Squibb Company | Phosphonate and phosphinate pyrazolylamide glucokinase activators |
| US8993544B2 (en) | 2009-02-09 | 2015-03-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Carbamoylphosphonates as inhibitors and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2835547B2 (ja) * | 1991-12-25 | 1998-12-14 | 株式会社大塚製薬工場 | 糖尿病治療剤 |
| AU702980B2 (en) * | 1995-12-27 | 1999-03-11 | Otsuka Pharmaceutical Factory, Inc. | Phosphonic diester derivatives |
| JP3785514B2 (ja) * | 1996-02-20 | 2006-06-14 | 株式会社大塚製薬工場 | ホスホン酸ジエステル誘導体 |
-
1998
- 1998-04-24 JP JP11553698A patent/JP4032193B2/ja not_active Expired - Fee Related
-
1999
- 1999-04-21 WO PCT/JP1999/002114 patent/WO1999055713A1/ja not_active Application Discontinuation
- 1999-04-21 EP EP99917075A patent/EP1074556B1/de not_active Expired - Lifetime
- 1999-04-21 AU AU35339/99A patent/AU756940B2/en not_active Ceased
- 1999-04-21 DE DE69911946T patent/DE69911946T2/de not_active Expired - Fee Related
- 1999-04-21 TW TW088106339A patent/TWI230711B/zh not_active IP Right Cessation
- 1999-04-21 CA CA002330111A patent/CA2330111A1/en not_active Abandoned
- 1999-04-21 KR KR1020007011250A patent/KR100753378B1/ko not_active IP Right Cessation
- 1999-04-21 CN CNB998049468A patent/CN1177852C/zh not_active Expired - Fee Related
- 1999-04-21 AT AT99917075T patent/ATE251632T1/de not_active IP Right Cessation
- 1999-04-21 US US09/674,145 patent/US6468992B1/en not_active Expired - Fee Related
-
2000
- 2000-10-23 NO NO20005328A patent/NO20005328L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1074556B1 (de) | 2003-10-08 |
| CN1177852C (zh) | 2004-12-01 |
| KR20010042580A (ko) | 2001-05-25 |
| WO1999055713A1 (fr) | 1999-11-04 |
| NO20005328L (no) | 2000-12-22 |
| US6468992B1 (en) | 2002-10-22 |
| EP1074556A4 (de) | 2002-04-24 |
| TWI230711B (en) | 2005-04-11 |
| CN1296489A (zh) | 2001-05-23 |
| JPH11302291A (ja) | 1999-11-02 |
| KR100753378B1 (ko) | 2007-08-30 |
| CA2330111A1 (en) | 1999-11-04 |
| DE69911946D1 (de) | 2003-11-13 |
| AU756940B2 (en) | 2003-01-30 |
| AU3533999A (en) | 1999-11-16 |
| NO20005328D0 (no) | 2000-10-23 |
| DE69911946T2 (de) | 2004-05-13 |
| EP1074556A1 (de) | 2001-02-07 |
| JP4032193B2 (ja) | 2008-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |