ATE375160T1 - Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen - Google Patents

Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen

Info

Publication number
ATE375160T1
ATE375160T1 AT00957914T AT00957914T ATE375160T1 AT E375160 T1 ATE375160 T1 AT E375160T1 AT 00957914 T AT00957914 T AT 00957914T AT 00957914 T AT00957914 T AT 00957914T AT E375160 T1 ATE375160 T1 AT E375160T1
Authority
AT
Austria
Prior art keywords
benicaent
mesoprogestins
hormone
prevention
dependent
Prior art date
Application number
AT00957914T
Other languages
English (en)
Inventor
Kristof Chwalisz
Walter Elger
Gerd Schubert
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of ATE375160T1 publication Critical patent/ATE375160T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
AT00957914T 1999-08-31 2000-08-31 Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen ATE375160T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38614199A 1999-08-31 1999-08-31

Publications (1)

Publication Number Publication Date
ATE375160T1 true ATE375160T1 (de) 2007-10-15

Family

ID=23524338

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00957914T ATE375160T1 (de) 1999-08-31 2000-08-31 Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen

Country Status (34)

Country Link
EP (1) EP1229906B1 (de)
JP (1) JP2003535029A (de)
KR (3) KR100864547B1 (de)
AR (1) AR025457A1 (de)
AT (1) ATE375160T1 (de)
AU (1) AU781840B2 (de)
BG (1) BG65817B1 (de)
BR (1) BR0014161A (de)
CA (1) CA2382580C (de)
CO (1) CO5200772A1 (de)
CZ (1) CZ2002704A3 (de)
DE (1) DE60036723T2 (de)
DK (1) DK1229906T3 (de)
EA (1) EA007854B1 (de)
EE (1) EE05172B1 (de)
ES (1) ES2295050T3 (de)
HR (1) HRP20020267A2 (de)
HU (1) HUP0202429A3 (de)
IL (1) IL148416A0 (de)
LT (1) LT5034B (de)
LV (1) LV12941B (de)
ME (1) MEP13808A (de)
MX (1) MXPA02002191A (de)
NO (1) NO20020999L (de)
NZ (1) NZ517471A (de)
PE (1) PE20010578A1 (de)
PL (1) PL198790B1 (de)
PT (1) PT1229906E (de)
RO (1) RO122179B1 (de)
RS (1) RS50283B (de)
SI (1) SI20852B (de)
SK (1) SK287192B6 (de)
UA (1) UA78184C2 (de)
WO (1) WO2001015679A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1525215B1 (de) * 2002-08-02 2006-09-06 Schering Aktiengesellschaft Progesteronrezeptormodulatoren mit erhöhter antigonadotroper aktivität für die weibliche fertilitätskontrolle und hormonersatztherapie
DE10236405A1 (de) 2002-08-02 2004-02-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie
US20040097591A1 (en) * 2002-11-18 2004-05-20 Kristof Chwalisz Use of selective progesterone receptor modulators for the treatment of androgen deficiency
DE102007011105A1 (de) 2007-03-02 2008-09-04 Bayer Schering Pharma Aktiengesellschaft Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose
ES2474765T3 (es) * 2009-06-17 2014-07-09 National University Corporation Kumamoto University Agente profiláctico y/o terapéutico para la dismenorrea
US8399432B2 (en) * 2009-10-27 2013-03-19 Lipogen Ltd. Compositions and methods of treatment for alleviating premenstrual syndrome symptoms
US20220339176A1 (en) * 2019-09-23 2022-10-27 The Board Of Trustees Of The Leland Stanford Junior University Methods of Treatments to Prolong Gestation and Complications of Menstruation or Gestation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3633244A1 (de) 1986-09-26 1988-03-31 Schering Ag Antigestagene zur hemmung der uterinen prostaglandinsynthese
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4332284C2 (de) 1993-09-20 1997-05-28 Jenapharm Gmbh 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5681817A (en) * 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
US5576310A (en) * 1994-09-20 1996-11-19 Jenapharm Gmbh 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds
PT800519E (pt) * 1994-12-22 2004-03-31 Ligand Pharm Inc Compostos moduladores de receptores de esteroides e metodos
US5696130A (en) * 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Tricyclic steroid receptor modulator compounds and methods
AU714959B2 (en) 1995-02-02 2000-01-13 Schering Aktiengesellschaft Progesterone antagonists for the production of pharmaceutical agents for the treatment of dysfunctional uterine bleeding
DE19604231A1 (de) * 1996-01-29 1997-07-31 Schering Ag Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen
DK0900234T3 (da) * 1996-05-01 2000-11-06 Us Gov Health & Human Serv 21-substituerede progesteronderivater anvendt som nye antigestagener
WO1998005679A2 (en) * 1996-08-05 1998-02-12 Duke University Mixed agonists of the progesterone receptor and assays therefor
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
EP1144396A2 (de) * 1999-01-14 2001-10-17 Bayer Corporation Substituierte 2-arylamino-heterocyclen und diese enthaltende zusammensetzungen zur verwendung als mittel, die den progesteron-rezeptor binden
CA2371273A1 (en) * 1999-05-04 2000-11-09 Andrew Fensome Tetracyclic progesterone receptor modulator compounds and methods

Also Published As

Publication number Publication date
CA2382580A1 (en) 2001-03-08
MXPA02002191A (es) 2002-09-30
KR20080066095A (ko) 2008-07-15
EA007854B1 (ru) 2007-02-27
WO2001015679A3 (en) 2001-11-22
EP1229906A2 (de) 2002-08-14
AU6946600A (en) 2001-03-26
BG106442A (bg) 2002-09-30
HUP0202429A3 (en) 2004-04-28
AU781840B2 (en) 2005-06-16
IL148416A0 (en) 2002-09-12
CO5200772A1 (es) 2002-09-27
LV12941B (en) 2003-06-20
DK1229906T3 (da) 2008-02-11
KR100864547B1 (ko) 2008-10-20
ES2295050T3 (es) 2008-04-16
HRP20020267A2 (en) 2004-04-30
WO2001015679A2 (en) 2001-03-08
EA200200282A1 (ru) 2002-10-31
BR0014161A (pt) 2002-05-21
KR100755109B1 (ko) 2007-09-04
SI20852A (sl) 2002-10-31
EE200200104A (et) 2003-04-15
CZ2002704A3 (cs) 2003-02-12
KR20020027616A (ko) 2002-04-13
AR025457A1 (es) 2002-11-27
MEP13808A (en) 2010-06-10
PT1229906E (pt) 2008-01-18
NO20020999L (no) 2002-03-14
JP2003535029A (ja) 2003-11-25
YU14002A (sh) 2006-01-16
LT2002031A (en) 2003-02-25
EP1229906B1 (de) 2007-10-10
NO20020999D0 (no) 2002-02-28
RS50283B (sr) 2009-09-08
PL198790B1 (pl) 2008-07-31
SK2992002A3 (en) 2002-07-02
LT5034B (lt) 2003-07-25
NZ517471A (en) 2004-02-27
DE60036723T2 (de) 2008-07-17
PL353930A1 (en) 2003-12-15
HUP0202429A2 (en) 2002-10-28
SI20852B (sl) 2009-06-30
BG65817B1 (bg) 2010-01-29
CA2382580C (en) 2009-05-19
RO122179B1 (ro) 2009-02-27
EE05172B1 (et) 2009-06-15
DE60036723D1 (de) 2007-11-22
SK287192B6 (sk) 2010-02-08
PE20010578A1 (es) 2001-06-04
KR20070058023A (ko) 2007-06-07
UA78184C2 (en) 2007-03-15

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