DE60036723D1 - Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen - Google Patents

Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen

Info

Publication number
DE60036723D1
DE60036723D1 DE60036723T DE60036723T DE60036723D1 DE 60036723 D1 DE60036723 D1 DE 60036723D1 DE 60036723 T DE60036723 T DE 60036723T DE 60036723 T DE60036723 T DE 60036723T DE 60036723 D1 DE60036723 D1 DE 60036723D1
Authority
DE
Germany
Prior art keywords
mesoprogestines
hormone
prevention
treatment
gynecological disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60036723T
Other languages
English (en)
Other versions
DE60036723T2 (de
Inventor
Kristof Chwalisz
Walter Elger
Gerd Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Application granted granted Critical
Publication of DE60036723D1 publication Critical patent/DE60036723D1/de
Publication of DE60036723T2 publication Critical patent/DE60036723T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
DE60036723T 1999-08-31 2000-08-31 Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen Expired - Lifetime DE60036723T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38614199A 1999-08-31 1999-08-31
US386141 1999-08-31
PCT/US2000/023770 WO2001015679A2 (en) 1999-08-31 2000-08-31 Mesoprogestins for the treatment and prevention of benign hormone dependent gynecological disorders

Publications (2)

Publication Number Publication Date
DE60036723D1 true DE60036723D1 (de) 2007-11-22
DE60036723T2 DE60036723T2 (de) 2008-07-17

Family

ID=23524338

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60036723T Expired - Lifetime DE60036723T2 (de) 1999-08-31 2000-08-31 Mesoprogestine zur behandlung und vorbeugung von hormonabhängigen gutartigen gynekologischen störungen

Country Status (34)

Country Link
EP (1) EP1229906B1 (de)
JP (1) JP2003535029A (de)
KR (3) KR100755109B1 (de)
AR (1) AR025457A1 (de)
AT (1) ATE375160T1 (de)
AU (1) AU781840B2 (de)
BG (1) BG65817B1 (de)
BR (1) BR0014161A (de)
CA (1) CA2382580C (de)
CO (1) CO5200772A1 (de)
CZ (1) CZ2002704A3 (de)
DE (1) DE60036723T2 (de)
DK (1) DK1229906T3 (de)
EA (1) EA007854B1 (de)
EE (1) EE05172B1 (de)
ES (1) ES2295050T3 (de)
HR (1) HRP20020267A2 (de)
HU (1) HUP0202429A3 (de)
IL (1) IL148416A0 (de)
LT (1) LT5034B (de)
LV (1) LV12941B (de)
ME (1) MEP13808A (de)
MX (1) MXPA02002191A (de)
NO (1) NO20020999L (de)
NZ (1) NZ517471A (de)
PE (1) PE20010578A1 (de)
PL (1) PL198790B1 (de)
PT (1) PT1229906E (de)
RO (1) RO122179B1 (de)
RS (1) RS50283B (de)
SI (1) SI20852B (de)
SK (1) SK287192B6 (de)
UA (1) UA78184C2 (de)
WO (1) WO2001015679A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005539016A (ja) * 2002-08-02 2005-12-22 シエーリング アクチエンゲゼルシャフト 女性用受胎調節及びホルモン置換療法のための高められた抗ゴナドトロピン活性を有するプロゲステロン受容体モジュレーター
DE10236405A1 (de) 2002-08-02 2004-02-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie
US20040097591A1 (en) * 2002-11-18 2004-05-20 Kristof Chwalisz Use of selective progesterone receptor modulators for the treatment of androgen deficiency
DE102007011105A1 (de) 2007-03-02 2008-09-04 Bayer Schering Pharma Aktiengesellschaft Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose
CA2765847A1 (en) * 2009-06-17 2010-12-23 National University Corporation Kumamoto University Prophylactic and/or therapeutic agent for dysmenorrhea
US8399432B2 (en) * 2009-10-27 2013-03-19 Lipogen Ltd. Compositions and methods of treatment for alleviating premenstrual syndrome symptoms
CA3152099A1 (en) * 2019-09-23 2021-04-01 Liang Liang Methods of treatments to prolong gestation and complications of menstruation or gestation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3633244A1 (de) 1986-09-26 1988-03-31 Schering Ag Antigestagene zur hemmung der uterinen prostaglandinsynthese
DE4332284C2 (de) 1993-09-20 1997-05-28 Jenapharm Gmbh 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5681817A (en) * 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
US5576310A (en) * 1994-09-20 1996-11-19 Jenapharm Gmbh 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds
US5688808A (en) * 1994-12-22 1997-11-18 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
DE69533180T2 (de) * 1994-12-22 2005-07-14 Ligand Pharmaceuticals, Inc., San Diego Steroidrezeptor-Modulator Verbindungen und Methoden
PT806952E (pt) 1995-02-02 2003-08-29 Schering Ag Antagonistas da progesterona para a preparacao de medicamentos para o tratamento de hemorragias uterinas disfuncionais
DE19604231A1 (de) * 1996-01-29 1997-07-31 Schering Ag Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen
PT900234E (pt) * 1996-05-01 2000-12-29 Us Gov Health & Human Serv Derivados de progesterona substituidos em 21 que podem ser utilizados como novos agentes antiprogestativos
WO1998005679A2 (en) * 1996-08-05 1998-02-12 Duke University Mixed agonists of the progesterone receptor and assays therefor
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
BR9916999A (pt) * 1999-01-14 2001-10-30 Bayer Ag Heterociclos de 2-arilimino substituìdos ecomposições contendo-os, para uso como agentesde ligação do receptor de progesterona
EP1175422A2 (de) * 1999-05-04 2002-01-30 Ligand Pharmaceuticals Incorporated Tetracyclische progesteronrezeptor-modulator-verbindungen und verfahren

Also Published As

Publication number Publication date
KR20070058023A (ko) 2007-06-07
LT2002031A (en) 2003-02-25
MXPA02002191A (es) 2002-09-30
SK2992002A3 (en) 2002-07-02
CZ2002704A3 (cs) 2003-02-12
KR100864547B1 (ko) 2008-10-20
AR025457A1 (es) 2002-11-27
PT1229906E (pt) 2008-01-18
EE200200104A (et) 2003-04-15
CA2382580C (en) 2009-05-19
SK287192B6 (sk) 2010-02-08
SI20852B (sl) 2009-06-30
SI20852A (sl) 2002-10-31
LT5034B (lt) 2003-07-25
CA2382580A1 (en) 2001-03-08
BG65817B1 (bg) 2010-01-29
EE05172B1 (et) 2009-06-15
RS50283B (sr) 2009-09-08
EA200200282A1 (ru) 2002-10-31
HUP0202429A3 (en) 2004-04-28
ATE375160T1 (de) 2007-10-15
DE60036723T2 (de) 2008-07-17
BR0014161A (pt) 2002-05-21
KR100755109B1 (ko) 2007-09-04
UA78184C2 (en) 2007-03-15
RO122179B1 (ro) 2009-02-27
PE20010578A1 (es) 2001-06-04
NO20020999D0 (no) 2002-02-28
EP1229906A2 (de) 2002-08-14
JP2003535029A (ja) 2003-11-25
NZ517471A (en) 2004-02-27
IL148416A0 (en) 2002-09-12
PL198790B1 (pl) 2008-07-31
AU781840B2 (en) 2005-06-16
AU6946600A (en) 2001-03-26
WO2001015679A3 (en) 2001-11-22
NO20020999L (no) 2002-03-14
PL353930A1 (en) 2003-12-15
CO5200772A1 (es) 2002-09-27
KR20080066095A (ko) 2008-07-15
HUP0202429A2 (en) 2002-10-28
DK1229906T3 (da) 2008-02-11
YU14002A (sh) 2006-01-16
WO2001015679A2 (en) 2001-03-08
HRP20020267A2 (en) 2004-04-30
ES2295050T3 (es) 2008-04-16
EA007854B1 (ru) 2007-02-27
EP1229906B1 (de) 2007-10-10
LV12941B (en) 2003-06-20
BG106442A (bg) 2002-09-30
KR20020027616A (ko) 2002-04-13
MEP13808A (en) 2010-06-10

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: BAYER SCHERING PHARMA AKIENGESELLSCHAFT, 13353, DE

8364 No opposition during term of opposition