ATE370133T1 - Thiazolinderivate als selektive androgenrezeptormodulatoren (sarms) - Google Patents
Thiazolinderivate als selektive androgenrezeptormodulatoren (sarms)Info
- Publication number
- ATE370133T1 ATE370133T1 AT04755044T AT04755044T ATE370133T1 AT E370133 T1 ATE370133 T1 AT E370133T1 AT 04755044 T AT04755044 T AT 04755044T AT 04755044 T AT04755044 T AT 04755044T AT E370133 T1 ATE370133 T1 AT E370133T1
- Authority
- AT
- Austria
- Prior art keywords
- androgen receptor
- sarms
- receptor modulators
- selective androgen
- thiazoline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47871203P | 2003-06-13 | 2003-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE370133T1 true ATE370133T1 (de) | 2007-09-15 |
Family
ID=33539114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04755044T ATE370133T1 (de) | 2003-06-13 | 2004-06-12 | Thiazolinderivate als selektive androgenrezeptormodulatoren (sarms) |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20050014952A1 (de) |
| EP (1) | EP1656360B1 (de) |
| JP (1) | JP4898446B2 (de) |
| CN (1) | CN1835937B (de) |
| AT (1) | ATE370133T1 (de) |
| AU (1) | AU2004249697B2 (de) |
| CA (1) | CA2528764A1 (de) |
| CY (1) | CY1106973T1 (de) |
| DE (1) | DE602004008300T2 (de) |
| DK (1) | DK1656360T3 (de) |
| ES (1) | ES2291906T3 (de) |
| PL (1) | PL1656360T3 (de) |
| PT (1) | PT1656360E (de) |
| WO (1) | WO2004113309A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2587678C (en) * | 2004-11-16 | 2013-05-21 | Janssen Pharmaceutica N.V. | Novel heterocycle derivatives useful as selective androgen receptor modulators (sarms) |
| US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
| US9284345B2 (en) | 2007-04-12 | 2016-03-15 | Endorecherche, Inc. | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators |
| CN104736569A (zh) * | 2012-01-12 | 2015-06-24 | 耶鲁大学 | 通过e3泛素连接酶增强靶蛋白质及其他多肽降解的化合物和方法 |
| CN103450112B (zh) * | 2013-08-07 | 2019-09-13 | 华东理工大学 | 一种n-桥连接的含氮五元杂环化合物及其制备与用途 |
| US9682960B2 (en) | 2013-12-19 | 2017-06-20 | Endorecherche, Inc. | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety |
| AU2020274113A1 (en) | 2019-05-14 | 2021-11-11 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| US11952349B2 (en) | 2019-11-13 | 2024-04-09 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| TW202304928A (zh) | 2021-03-23 | 2023-02-01 | 美商諾維雪碧歐公司 | 抗癌核荷爾蒙受體標靶化合物 |
| IL308104A (en) | 2021-05-03 | 2023-12-01 | Nuvation Bio Inc | Nuclear hormone receptor-targeted compounds against cancer |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9506625A (pt) * | 1994-01-24 | 1997-09-30 | Du Pont | Composto composição artropodicida e método para controle de artrópodos |
| US6403623B1 (en) * | 1999-05-27 | 2002-06-11 | Unuversity Of Notre Dame Du Lac | Heterocyclic antituberculosis agents |
| PT1401801E (pt) * | 2000-08-24 | 2007-02-28 | Univ Tennessee Res Foundation | Modulares selectivos de receptor de androgénio e métodos para a sua utilização |
-
2004
- 2004-06-12 DK DK04755044T patent/DK1656360T3/da active
- 2004-06-12 AT AT04755044T patent/ATE370133T1/de active
- 2004-06-12 US US10/866,591 patent/US20050014952A1/en not_active Abandoned
- 2004-06-12 JP JP2006533745A patent/JP4898446B2/ja not_active Expired - Fee Related
- 2004-06-12 EP EP04755044A patent/EP1656360B1/de not_active Expired - Lifetime
- 2004-06-12 PL PL04755044T patent/PL1656360T3/pl unknown
- 2004-06-12 PT PT04755044T patent/PT1656360E/pt unknown
- 2004-06-12 WO PCT/US2004/018665 patent/WO2004113309A1/en active IP Right Grant
- 2004-06-12 CN CN2004800230915A patent/CN1835937B/zh not_active Expired - Fee Related
- 2004-06-12 AU AU2004249697A patent/AU2004249697B2/en not_active Ceased
- 2004-06-12 CA CA002528764A patent/CA2528764A1/en not_active Abandoned
- 2004-06-12 DE DE602004008300T patent/DE602004008300T2/de not_active Expired - Lifetime
- 2004-06-12 ES ES04755044T patent/ES2291906T3/es not_active Expired - Lifetime
-
2007
- 2007-11-05 CY CY20071101413T patent/CY1106973T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1835937B (zh) | 2012-07-18 |
| JP2007501287A (ja) | 2007-01-25 |
| DE602004008300D1 (de) | 2007-09-27 |
| US20050014952A1 (en) | 2005-01-20 |
| EP1656360A1 (de) | 2006-05-17 |
| DK1656360T3 (da) | 2007-12-27 |
| PT1656360E (pt) | 2007-10-22 |
| ES2291906T3 (es) | 2008-03-01 |
| CA2528764A1 (en) | 2004-12-29 |
| PL1656360T3 (pl) | 2008-01-31 |
| AU2004249697B2 (en) | 2010-04-22 |
| CY1106973T1 (el) | 2012-09-26 |
| CN1835937A (zh) | 2006-09-20 |
| DE602004008300T2 (de) | 2008-05-08 |
| JP4898446B2 (ja) | 2012-03-14 |
| AU2004249697A1 (en) | 2004-12-29 |
| EP1656360B1 (de) | 2007-08-15 |
| WO2004113309A1 (en) | 2004-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW200621235A (en) | Novel heterocycle derivatives useful as selective androgen receptor modulators (sarms) | |
| TW200621725A (en) | Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms) | |
| TW200624424A (en) | Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms) | |
| TW200606146A (en) | Novel indole derivatives as selective androgen receptor modulators (SARMS) | |
| WO2006031715A3 (en) | Novel imidazolidin-2-one derivatives as selective androgen receptor modulators (sarms) | |
| SG10201809390QA (en) | Modulators of indoleamine 2,3-dioxygenase and methods of using the same | |
| EA200870196A1 (ru) | Индолсульфонамидные модуляторы рецепторов прогестерона | |
| EA200700489A1 (ru) | Новые бензоконденсированные гетероарилсульфамидные производные, полезные в качестве противоконвульсивных средств | |
| CY1106973T1 (el) | Παραγωγα θειαζολινης ως εκλεκτικοι διαμορφωται υποδοχεως ανδρογονου (sarms) | |
| ATE472529T1 (de) | Prolinamidderivate als natriumkanalmodulatoren | |
| TW200604170A (en) | Novel indole derivatives as selective androgen receptor modulators (SARMs) | |
| MY143211A (en) | Novel indole derivatives as selective androgen receptor modulators (sarms) | |
| DE60309739D1 (de) | Pyridinderivate als modulatoren des cb2-rezeptors | |
| NO20076479L (no) | Nye oksadiazolderivater og anvendelse derav som positive allosteriske metabotropiske modulatorer av glutamatreseptorer | |
| ATE493397T1 (de) | Neuartige tetrazolderivate als positive allosterische modulatoren von metabotropen glutamatrezeptoren | |
| NO20064325L (no) | Heteroarylaminopyrazolderivativer nyttige for behandling av diabetes | |
| NO20082122L (no) | Kvaternaere alfa-aminokarboksamidderivater som modulatorer av spenningsutlops natriumkanaler | |
| RS20080246A (en) | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | |
| ATE467632T1 (de) | Pyrroloä2,3-büpyridinderivate als modulatoren des h3-rezeptors | |
| EA200601267A1 (ru) | Модуляторы рецепторов андрогена | |
| ATE473741T1 (de) | Neue imidazolopyrazolderivate als selektive androgen-rezeptor-modulatoren | |
| ES2345882T3 (es) | Nuevos compuestos y su uso como moduladores de ppar. | |
| ATE419242T1 (de) | Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren | |
| ATE540953T1 (de) | Bizyklische imidazol- oder thiadiazol- heterozyklen als selektive androgen-rezeptor- modulatoren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1656360 Country of ref document: EP |