ATE363283T1 - Terfenadin-carboxylat und die behandlung von hautreizung - Google Patents

Terfenadin-carboxylat und die behandlung von hautreizung

Info

Publication number
ATE363283T1
ATE363283T1 AT02006356T AT02006356T ATE363283T1 AT E363283 T1 ATE363283 T1 AT E363283T1 AT 02006356 T AT02006356 T AT 02006356T AT 02006356 T AT02006356 T AT 02006356T AT E363283 T1 ATE363283 T1 AT E363283T1
Authority
AT
Austria
Prior art keywords
treatment
skin irritation
compound
formula
terfenadine carboxylate
Prior art date
Application number
AT02006356T
Other languages
English (en)
Inventor
James W Young
Nancy M Gray
Raymond L Woosley
Yiwang Chen
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27129882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE363283(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sepracor Inc filed Critical Sepracor Inc
Application granted granted Critical
Publication of ATE363283T1 publication Critical patent/ATE363283T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
AT02006356T 1992-08-03 1993-08-03 Terfenadin-carboxylat und die behandlung von hautreizung ATE363283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92415692A 1992-08-03 1992-08-03
US92418292A 1992-08-03 1992-08-03

Publications (1)

Publication Number Publication Date
ATE363283T1 true ATE363283T1 (de) 2007-06-15

Family

ID=27129882

Family Applications (3)

Application Number Title Priority Date Filing Date
AT97104837T ATE322899T1 (de) 1992-08-03 1993-08-03 Terfenadin-carboxylat und die behandlung von allergischen erkrankungen
AT02006356T ATE363283T1 (de) 1992-08-03 1993-08-03 Terfenadin-carboxylat und die behandlung von hautreizung
AT93918584T ATE162399T1 (de) 1992-08-03 1993-08-03 Terfanadin metaboliten und deren optisch reine isomere zur behandlung von allergischen krankheiten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT97104837T ATE322899T1 (de) 1992-08-03 1993-08-03 Terfenadin-carboxylat und die behandlung von allergischen erkrankungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT93918584T ATE162399T1 (de) 1992-08-03 1993-08-03 Terfanadin metaboliten und deren optisch reine isomere zur behandlung von allergischen krankheiten

Country Status (24)

Country Link
US (1) US5375693A (de)
EP (4) EP0815860B1 (de)
JP (6) JP3041954B2 (de)
KR (1) KR950702420A (de)
AT (3) ATE322899T1 (de)
AU (3) AU675240B2 (de)
BR (1) BR9306841A (de)
CA (1) CA2141572C (de)
CZ (1) CZ27495A3 (de)
DE (5) DE701443T1 (de)
DK (3) DK0815860T3 (de)
ES (3) ES2257757T3 (de)
FI (1) FI950467L (de)
GB (1) GB2284351B (de)
GR (3) GR960300024T1 (de)
HK (1) HK1045806B (de)
HU (1) HU226242B1 (de)
NO (1) NO310644B1 (de)
PL (1) PL174373B1 (de)
PT (2) PT815860E (de)
RO (1) RO116043B1 (de)
RU (1) RU2167657C2 (de)
SK (1) SK12495A3 (de)
WO (1) WO1994003170A1 (de)

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WO1994003170A1 (en) 1992-08-03 1994-02-17 Sepracor Inc. Terfenadine metabolites and their optically pure isomers for treating allergic disorders
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
DK1026147T3 (da) * 1993-06-24 2004-03-22 Albany Molecular Res Inc Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
CA2585705C (en) 1994-05-18 2012-04-17 Aventis Pharmaceuticals Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
US5455049A (en) * 1995-01-04 1995-10-03 Ascent Pharmaceuticals, Inc. Terfenadine oral powder
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US5837284A (en) 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
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US5922736A (en) * 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
US5733756A (en) * 1996-01-05 1998-03-31 Celgene Corporation Lactams and processes for stereoselective enrichment of lactams, amides, and esters
US6355656B1 (en) 1995-12-04 2002-03-12 Celgene Corporation Phenidate drug formulations having diminished abuse potential
US6153754A (en) 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
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US5925761A (en) * 1997-02-04 1999-07-20 Sepracor Inc. Synthesis of terfenadine and derivatives
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
PT998272E (pt) * 1997-08-26 2003-09-30 Aventis Pharma Inc Composicao farmaceutica para combinacao do descongestionante piperidinoalcanol
US6194431B1 (en) * 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
DE19913862C2 (de) * 1999-03-26 2003-04-10 Forschungszentrum Juelich Gmbh Verfahren zur biokatalysierten Umsetzung schlecht wasserlöslicher Substanzen
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
EP1392303A4 (de) * 2001-04-09 2005-01-26 Teva Pharma Polymorphe von fexofenadin-hydrochlorid
KR20040015734A (ko) * 2001-06-18 2004-02-19 닥터 레디스 레보러터리즈 리미티드 4-[4-[4-(히드록실디페닐메틸)-1-피페리디닐]-1-히드록시부틸]-α,α-디메틸벤젠 아세트산 및 그 염산염의 신규 결정형태
WO2003020274A1 (en) * 2001-08-30 2003-03-13 Aventis Pharmaceuticals Inc. Treatment of atopic dermatitis
AU2003248657A1 (en) * 2002-06-10 2003-12-22 Teva Pharmaceutical Industries Ltd. Polymorphic form xvi of fexofenadine hydrochloride
TWI326214B (en) * 2002-07-17 2010-06-21 Avanir Pharmaceuticals Inc Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
RU2238081C1 (ru) * 2003-07-14 2004-10-20 Открытое акционерное общество "Московская фармацевтическая фабрика" Средство антиконгестивного действия
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
JP4515121B2 (ja) 2004-03-15 2010-07-28 東芝テック株式会社 ワイヤドットプリンタヘッド及びワイヤドットプリンタ
JP4473021B2 (ja) 2004-03-22 2010-06-02 東芝テック株式会社 窒化層形成方法、磁気回路形成部材、アーマチュア、ワイヤドットプリンタヘッド及びワイヤドットプリンタ
EP1628959A2 (de) * 2004-04-26 2006-03-01 Teva Pharmaceutical Industries Ltd Polymorphe form xvi von fexofenadine-hydrochlorid
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
US7498443B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of carebastine
US7498345B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US20060148851A1 (en) * 2004-09-28 2006-07-06 Shlomit Wizel Fexofenadine crystal form and processes for its preparation thereof
NZ555842A (en) * 2004-12-09 2010-10-29 Celgene Corp Treatment of various conditions of patients with Tourette syndrome, tics, or a family history thereof sing D-threo methylphenidate free from other isomers
AU2006311577B2 (en) 2005-11-09 2013-02-07 Zalicus Inc. Methods, compositions, and kits for the treatment of medical conditions
EP2420238A3 (de) * 2007-04-13 2012-03-07 Southern Research Institute Anti-Angiogenese-Mittel
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
US20150238473A1 (en) 2012-09-27 2015-08-27 University Of Rochester Methods and compositions for treating infection
NZ735777A (en) * 2015-03-26 2023-03-31 Jacqueline M Iversen Methods and compositions to inhibit symptoms associated with veisalgia
DE102017130361A1 (de) 2017-12-18 2019-07-04 Lsp Innovative Automotive Systems Gmbh Statorzahn und Stator mit guter elektrischer Isolierung und gleichzeitig sehr hoher Wärmeleitfähigkeit zur Leistungssteigerung von Elektromotoren

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US4552899A (en) † 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4829064A (en) † 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
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EP0639976B1 (de) † 1992-05-11 2000-07-26 Merrell Pharmaceuticals Inc. Verwendung von terfenadin-derivaten als antihistaminika in leberkranken patienten
WO1994003170A1 (en) 1992-08-03 1994-02-17 Sepracor Inc. Terfenadine metabolites and their optically pure isomers for treating allergic disorders
DK1026147T3 (da) * 1993-06-24 2004-03-22 Albany Molecular Res Inc Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater
HU226037B1 (en) * 1993-06-25 2008-03-28 Aventis Inc Process for producing antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives and novel intermediates
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Also Published As

Publication number Publication date
JP2000086515A (ja) 2000-03-28
CZ27495A3 (en) 1996-09-11
ES2284740T3 (es) 2007-11-16
JP3288661B2 (ja) 2002-06-04
HUT71889A (en) 1996-02-28
FI950467A0 (fi) 1995-02-02
JP3288660B2 (ja) 2002-06-04
GR960300024T1 (en) 1996-05-31
ATE322899T1 (de) 2006-04-15
AU7182296A (en) 1997-01-30
HK1045806A1 (en) 2002-12-13
GB2284351A (en) 1995-06-07
DE69334145T2 (de) 2008-01-24
DK0815860T3 (da) 2006-08-14
CA2141572A1 (en) 1994-02-17
RO116043B1 (ro) 2000-10-30
ES2086270T1 (es) 1996-07-01
NO310644B1 (no) 2001-08-06
DE69316660D1 (de) 1998-02-26
EP1214937B1 (de) 2007-05-30
CA2141572C (en) 2001-02-06
GR3035417T3 (en) 2001-05-31
DE9320925U1 (de) 1995-08-31
WO1994003170A1 (en) 1994-02-17
FI950467A7 (fi) 1995-03-31
BR9306841A (pt) 1998-12-08
AU1842999A (en) 1999-04-29
KR950702420A (ko) 1995-07-29
AU4798693A (en) 1994-03-03
EP0701443B2 (de) 2000-11-22
ES2257757T3 (es) 2006-08-01
NO950374L (no) 1995-03-29
JP2000086512A (ja) 2000-03-28
JP2000086514A (ja) 2000-03-28
PT815860E (pt) 2006-08-31
HK1045806B (en) 2008-03-14
EP1688142A1 (de) 2006-08-09
PT1214937E (pt) 2007-07-25
PL307339A1 (en) 1995-05-15
FI950467L (fi) 1995-03-31
AU675240B2 (en) 1997-01-30
JPH08500348A (ja) 1996-01-16
EP1214937A3 (de) 2002-10-30
EP0701443B1 (de) 1998-01-21
GR3026530T3 (en) 1998-07-31
DE69316660T2 (de) 1998-05-07
GB2284351B (en) 1996-11-27
EP1214937A2 (de) 2002-06-19
RU95107881A (ru) 1996-11-27
ATE162399T1 (de) 1998-02-15
JP3037697B2 (ja) 2000-04-24
JP3288662B2 (ja) 2002-06-04
DE69334008T2 (de) 2006-10-19
GB9502183D0 (en) 1995-03-22
RU2167657C2 (ru) 2001-05-27
PL174373B1 (pl) 1998-07-31
JP3041954B2 (ja) 2000-05-15
DK0701443T4 (da) 2000-12-18
DE69316660T3 (de) 2001-04-05
SK12495A3 (en) 1997-01-08
ES2086270T5 (es) 2001-02-01
DK1214937T3 (da) 2007-09-17
JP2000086516A (ja) 2000-03-28
EP0815860B1 (de) 2006-04-12
US5375693A (en) 1994-12-27
JP2000086513A (ja) 2000-03-28
DE69334145D1 (de) 2007-07-12
HU9500313D0 (en) 1995-03-28
HU226242B1 (en) 2008-07-28
NO950374D0 (no) 1995-02-01
ES2086270T3 (es) 1998-03-01
EP0701443A1 (de) 1996-03-20
EP0815860A3 (de) 1998-01-14
EP0815860A2 (de) 1998-01-07
DE701443T1 (de) 1997-01-30
DK0701443T3 (da) 1998-02-09
DE69334008D1 (de) 2006-05-24

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