ATE361935T1 - Monoklonale antikörper spezifisch für die extrazelluläre domäne des prostata-spezifischen membranantigens - Google Patents

Monoklonale antikörper spezifisch für die extrazelluläre domäne des prostata-spezifischen membranantigens

Info

Publication number
ATE361935T1
ATE361935T1 AT99913932T AT99913932T ATE361935T1 AT E361935 T1 ATE361935 T1 AT E361935T1 AT 99913932 T AT99913932 T AT 99913932T AT 99913932 T AT99913932 T AT 99913932T AT E361935 T1 ATE361935 T1 AT E361935T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
prostate
psma
extracellular domain
antibodies
Prior art date
Application number
AT99913932T
Other languages
German (de)
English (en)
Inventor
Gerald Murphy
Alton Boynton
Eric Holmes
William Tino
Original Assignee
Medarex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medarex Inc filed Critical Medarex Inc
Application granted granted Critical
Publication of ATE361935T1 publication Critical patent/ATE361935T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT99913932T 1998-03-18 1999-03-18 Monoklonale antikörper spezifisch für die extrazelluläre domäne des prostata-spezifischen membranantigens ATE361935T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/044,668 US6150508A (en) 1996-03-25 1998-03-18 Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen

Publications (1)

Publication Number Publication Date
ATE361935T1 true ATE361935T1 (de) 2007-06-15

Family

ID=21933651

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99913932T ATE361935T1 (de) 1998-03-18 1999-03-18 Monoklonale antikörper spezifisch für die extrazelluläre domäne des prostata-spezifischen membranantigens

Country Status (13)

Country Link
US (1) US6150508A (https=)
EP (2) EP1064303B1 (https=)
JP (1) JP4229591B2 (https=)
AT (1) ATE361935T1 (https=)
AU (1) AU768558B2 (https=)
CA (1) CA2323096C (https=)
CY (1) CY1106790T1 (https=)
DE (1) DE69936049T2 (https=)
DK (1) DK1064303T3 (https=)
ES (1) ES2288017T3 (https=)
IL (2) IL138497A0 (https=)
PT (1) PT1064303E (https=)
WO (1) WO1999047554A1 (https=)

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US6569432B1 (en) * 1995-02-24 2003-05-27 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen and uses thereof
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US20030180290A1 (en) * 1995-06-07 2003-09-25 Idec Pharmaceuticals Corporation Anti-CD80 antibody having ADCC activity for ADCC mediated killing of B cell lymphoma cells alone or in combination with other therapies
US20040253246A1 (en) * 1996-02-23 2004-12-16 Israeli Ron S. Prostate-specific membrane antigen and uses thereof
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US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
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US8507445B2 (en) 2001-09-07 2013-08-13 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer
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Also Published As

Publication number Publication date
DE69936049T2 (de) 2008-01-10
IL138497A0 (en) 2001-10-31
EP1064303A1 (en) 2001-01-03
CA2323096C (en) 2004-10-19
JP2002506629A (ja) 2002-03-05
EP1064303B1 (en) 2007-05-09
JP4229591B2 (ja) 2009-02-25
WO1999047554A1 (en) 1999-09-23
EP1854808A2 (en) 2007-11-14
ES2288017T3 (es) 2007-12-16
CA2323096A1 (en) 1999-09-23
US6150508A (en) 2000-11-21
IL138497A (en) 2007-07-04
DE69936049D1 (de) 2007-06-21
AU768558B2 (en) 2003-12-18
CY1106790T1 (el) 2012-05-23
AU3189699A (en) 1999-10-11
EP1854808A3 (en) 2008-02-27
DK1064303T3 (da) 2007-09-17
EP1064303A4 (en) 2005-03-02
PT1064303E (pt) 2007-08-21

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