ATE353927T1 - Lipid-polymer konjugaten - Google Patents

Lipid-polymer konjugaten

Info

Publication number
ATE353927T1
ATE353927T1 AT02754661T AT02754661T ATE353927T1 AT E353927 T1 ATE353927 T1 AT E353927T1 AT 02754661 T AT02754661 T AT 02754661T AT 02754661 T AT02754661 T AT 02754661T AT E353927 T1 ATE353927 T1 AT E353927T1
Authority
AT
Austria
Prior art keywords
lipid
polymer conjugates
poly
amino acid
conjugates
Prior art date
Application number
AT02754661T
Other languages
German (de)
English (en)
Inventor
J M Metselaar
W E Hennink
Vringer Tom De
Boer L W T De
C Oussoren
G Storm
P Bruin
Original Assignee
Astellas Pharma Europ B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Europ B V filed Critical Astellas Pharma Europ B V
Application granted granted Critical
Publication of ATE353927T1 publication Critical patent/ATE353927T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Polyamides (AREA)
  • Peptides Or Proteins (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Cosmetics (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02754661T 2001-06-01 2002-06-03 Lipid-polymer konjugaten ATE353927T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01202107 2001-06-01

Publications (1)

Publication Number Publication Date
ATE353927T1 true ATE353927T1 (de) 2007-03-15

Family

ID=8180408

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02754661T ATE353927T1 (de) 2001-06-01 2002-06-03 Lipid-polymer konjugaten
AT02748799T ATE416214T1 (de) 2001-06-01 2002-06-03 Zusammensetzungen enthaltend lipid-polymer konjugate

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT02748799T ATE416214T1 (de) 2001-06-01 2002-06-03 Zusammensetzungen enthaltend lipid-polymer konjugate

Country Status (20)

Country Link
US (3) US20040241222A1 (enExample)
EP (2) EP1392756B1 (enExample)
JP (2) JP2004527586A (enExample)
KR (2) KR100874847B1 (enExample)
CN (2) CN1308375C (enExample)
AT (2) ATE353927T1 (enExample)
BR (2) BR0209699A (enExample)
CA (2) CA2448856A1 (enExample)
CZ (2) CZ20033480A3 (enExample)
DE (2) DE60218154T2 (enExample)
EE (2) EE200300596A (enExample)
ES (2) ES2318027T3 (enExample)
HR (2) HRP20030976A2 (enExample)
HU (2) HUP0400174A2 (enExample)
MX (2) MXPA03011049A (enExample)
NO (2) NO20035263D0 (enExample)
PL (2) PL367479A1 (enExample)
SK (2) SK15972003A3 (enExample)
WO (2) WO2002098951A2 (enExample)
ZA (2) ZA200308937B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL367479A1 (en) * 2001-06-01 2005-02-21 Yamanouchi Europe B.V. Lipid-polymer-conjugates compositions
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
EP1393720A1 (en) * 2002-08-27 2004-03-03 Universiteit Utrecht Vesicle-encapsulated corticosteroids for treatment of cancer
SG113442A1 (en) * 2002-11-29 2005-08-29 Agency Science Tech & Res Improved temperature sensitive micelles
FR2855521B1 (fr) 2003-05-28 2005-08-05 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.
EP1481683A1 (en) * 2003-05-30 2004-12-01 Yamanouchi Pharmaceutical Co. Ltd. P-selectin targeting ligand and compositions thereof
SE527505C2 (sv) * 2003-06-10 2006-03-28 Anna Imberg Komposita material och partiklar
FR2860516B1 (fr) * 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
US20100036093A1 (en) * 2006-05-09 2010-02-11 Osaka University Cholesterolamine-introduced poly-gamma-glutamic acid derivative
JP4936312B2 (ja) * 2006-07-20 2012-05-23 株式会社島津製作所 新規な両親媒性物質、それを用いた薬剤搬送システム及び分子イメージングシステム
JP5258189B2 (ja) * 2006-11-09 2013-08-07 学校法人 関西大学 柔軟性生分解性ポリマー
ITRM20070327A1 (it) * 2007-06-11 2008-12-12 Univ Palermo Vettori colloidali a struttura poliamminoacidica per il rilascio orale di peptidi e proteine e relativo metodo di produzione.
US20090285882A1 (en) * 2008-04-22 2009-11-19 Jochen Weiss Stabilized Liposome Compositions and Related Methods of Use
KR101695836B1 (ko) 2010-04-13 2017-01-16 (주)아모레퍼시픽 경피흡수용 고분자-리포좀 나노복합체 조성물 및 그 제조방법
ES2385995B2 (es) * 2011-01-10 2013-05-21 Universidade De Santiago De Compostela Nanocápsulas con cubierta polimérica
US9993427B2 (en) * 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
JPWO2019172362A1 (ja) * 2018-03-07 2021-03-11 公益財団法人川崎市産業振興財団 刺激応答性ポリマー
WO2023282296A1 (ja) * 2021-07-07 2023-01-12 日油株式会社 ｐＨ応答性脂質誘導体
WO2024232832A1 (en) * 2023-05-11 2024-11-14 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound and related methods thereof
WO2025021942A1 (en) 2023-07-27 2025-01-30 Bracco Suisse Sa Ultrasound responsive vesicles containing lipid-polyamino acid conjugates
WO2025031991A1 (en) * 2023-08-04 2025-02-13 Polypeptide Therapeutic Solutions, S.L. Stealth-stabilized sulfur-containing lipo/polyamino acids
WO2025080209A1 (en) * 2023-10-10 2025-04-17 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound and related methods thereof
WO2025090023A1 (en) * 2023-10-24 2025-05-01 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound, and related methods thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0657722B2 (ja) * 1986-05-27 1994-08-03 三菱化成株式会社 水溶性ポリマ−組成物
US5149794A (en) * 1990-11-01 1992-09-22 State Of Oregon Covalent lipid-drug conjugates for drug targeting
US5395619A (en) * 1993-03-03 1995-03-07 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
US5972379A (en) * 1995-02-14 1999-10-26 Sequus Pharmaceuticals, Inc. Liposome composition and method for administering a quinolone
US6197332B1 (en) * 1997-08-13 2001-03-06 Chiron Corporation Lipid-conjugated polyamide compounds and related compositions and methods thereof
GB9811059D0 (en) * 1998-05-23 1998-07-22 Univ Strathclyde Polyamino acid vesicles
PL367479A1 (en) * 2001-06-01 2005-02-21 Yamanouchi Europe B.V. Lipid-polymer-conjugates compositions

Also Published As

Publication number Publication date
US20040241222A1 (en) 2004-12-02
US20040254352A1 (en) 2004-12-16
WO2002098951A3 (en) 2003-02-20
NO20035263D0 (no) 2003-11-27
JP2004527586A (ja) 2004-09-09
EE200300598A (et) 2004-02-16
KR20040027513A (ko) 2004-04-01
EP1392755B1 (en) 2008-12-03
CZ20033480A3 (cs) 2004-07-14
KR100874847B1 (ko) 2008-12-19
WO2002098952A1 (en) 2002-12-12
EE200300596A (et) 2004-02-16
DE60218154T2 (de) 2007-10-31
DE60230137D1 (de) 2009-01-15
KR20040027512A (ko) 2004-04-01
NO20035264D0 (no) 2003-11-27
US20100145018A1 (en) 2010-06-10
CN1520435A (zh) 2004-08-11
DE60218154D1 (de) 2007-03-29
HRP20030976A2 (en) 2005-08-31
CA2448856A1 (en) 2002-12-12
MXPA03011050A (es) 2004-06-25
BR0209699A (pt) 2005-02-01
KR100894852B1 (ko) 2009-04-24
EP1392756B1 (en) 2007-02-14
HUP0400174A2 (en) 2007-02-28
ZA200308938B (en) 2004-11-17
CN1271116C (zh) 2006-08-23
MXPA03011049A (es) 2004-06-25
HRP20030975A2 (en) 2005-08-31
ZA200308937B (en) 2004-11-17
SK15982003A3 (sk) 2004-06-08
WO2002098951A2 (en) 2002-12-12
CN1602326A (zh) 2005-03-30
JP2004527585A (ja) 2004-09-09
EP1392755A1 (en) 2004-03-03
CA2448858A1 (en) 2002-12-12
CN1308375C (zh) 2007-04-04
SK15972003A3 (sk) 2004-06-08
EP1392756A2 (en) 2004-03-03
ES2282439T3 (es) 2007-10-16
HUP0400171A2 (en) 2007-02-28
PL367479A1 (en) 2005-02-21
PL369455A1 (en) 2005-04-18
CZ20033479A3 (cs) 2004-07-14
ATE416214T1 (de) 2008-12-15
ES2318027T3 (es) 2009-05-01
BR0209695A (pt) 2005-01-11

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