KR100874847B1 - 지질-폴리머-접합체 - Google Patents

지질-폴리머-접합체 Download PDF

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Publication number
KR100874847B1
KR100874847B1 KR1020037015720A KR20037015720A KR100874847B1 KR 100874847 B1 KR100874847 B1 KR 100874847B1 KR 1020037015720 A KR1020037015720 A KR 1020037015720A KR 20037015720 A KR20037015720 A KR 20037015720A KR 100874847 B1 KR100874847 B1 KR 100874847B1
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KR
South Korea
Prior art keywords
polymer
poly
conjugate
lipid
dodasuc
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Expired - Fee Related
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KR1020037015720A
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English (en)
Korean (ko)
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KR20040027512A (ko
Inventor
메트세라아르조스베르트마아르텐
헨닌크윌헬무스에베라르두스
드브링거톰
드보에르레오나르두스윌헬무스테오도루스
오우쏘렌크리스티엔
스톰게리트
브루인피터
Original Assignee
아스텔라스 파마 유럽 비.브이.
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Publication of KR20040027512A publication Critical patent/KR20040027512A/ko
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Polyamides (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020037015720A 2001-06-01 2002-06-03 지질-폴리머-접합체 Expired - Fee Related KR100874847B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01202107.7 2001-06-01
EP01202107 2001-06-01
PCT/EP2002/006432 WO2002098951A2 (en) 2001-06-01 2002-06-03 Lipid-polymer-conjugates

Publications (2)

Publication Number Publication Date
KR20040027512A KR20040027512A (ko) 2004-04-01
KR100874847B1 true KR100874847B1 (ko) 2008-12-19

Family

ID=8180408

Family Applications (2)

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KR1020037015720A Expired - Fee Related KR100874847B1 (ko) 2001-06-01 2002-06-03 지질-폴리머-접합체
KR1020037015722A Expired - Fee Related KR100894852B1 (ko) 2001-06-01 2002-06-03 지질-폴리머-접합체 조성물

Family Applications After (1)

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KR1020037015722A Expired - Fee Related KR100894852B1 (ko) 2001-06-01 2002-06-03 지질-폴리머-접합체 조성물

Country Status (20)

Country Link
US (3) US20040254352A1 (enExample)
EP (2) EP1392756B1 (enExample)
JP (2) JP2004527585A (enExample)
KR (2) KR100874847B1 (enExample)
CN (2) CN1271116C (enExample)
AT (2) ATE416214T1 (enExample)
BR (2) BR0209695A (enExample)
CA (2) CA2448856A1 (enExample)
CZ (2) CZ20033480A3 (enExample)
DE (2) DE60230137D1 (enExample)
EE (2) EE200300598A (enExample)
ES (2) ES2282439T3 (enExample)
HR (2) HRP20030975A2 (enExample)
HU (2) HUP0400171A2 (enExample)
MX (2) MXPA03011050A (enExample)
NO (2) NO20035263D0 (enExample)
PL (2) PL367479A1 (enExample)
SK (2) SK15972003A3 (enExample)
WO (2) WO2002098951A2 (enExample)
ZA (2) ZA200308937B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE416214T1 (de) * 2001-06-01 2008-12-15 Astellas Pharma Europ B V Zusammensetzungen enthaltend lipid-polymer konjugate
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
EP1393720A1 (en) * 2002-08-27 2004-03-03 Universiteit Utrecht Vesicle-encapsulated corticosteroids for treatment of cancer
SG113442A1 (en) * 2002-11-29 2005-08-29 Agency Science Tech & Res Improved temperature sensitive micelles
FR2855521B1 (fr) 2003-05-28 2005-08-05 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.
EP1481683A1 (en) * 2003-05-30 2004-12-01 Yamanouchi Pharmaceutical Co. Ltd. P-selectin targeting ligand and compositions thereof
SE527505C2 (sv) * 2003-06-10 2006-03-28 Anna Imberg Komposita material och partiklar
FR2860516B1 (fr) * 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
US20100036093A1 (en) * 2006-05-09 2010-02-11 Osaka University Cholesterolamine-introduced poly-gamma-glutamic acid derivative
JP4936312B2 (ja) * 2006-07-20 2012-05-23 株式会社島津製作所 新規な両親媒性物質、それを用いた薬剤搬送システム及び分子イメージングシステム
JP5258189B2 (ja) * 2006-11-09 2013-08-07 学校法人 関西大学 柔軟性生分解性ポリマー
ITRM20070327A1 (it) * 2007-06-11 2008-12-12 Univ Palermo Vettori colloidali a struttura poliamminoacidica per il rilascio orale di peptidi e proteine e relativo metodo di produzione.
US20090285882A1 (en) * 2008-04-22 2009-11-19 Jochen Weiss Stabilized Liposome Compositions and Related Methods of Use
KR101695836B1 (ko) 2010-04-13 2017-01-16 (주)아모레퍼시픽 경피흡수용 고분자-리포좀 나노복합체 조성물 및 그 제조방법
ES2385995B2 (es) * 2011-01-10 2013-05-21 Universidade De Santiago De Compostela Nanocápsulas con cubierta polimérica
US9993427B2 (en) * 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
WO2019172362A1 (ja) * 2018-03-07 2019-09-12 公益財団法人川崎市産業振興財団 刺激応答性ポリマー
WO2023282296A1 (ja) * 2021-07-07 2023-01-12 日油株式会社 ｐＨ応答性脂質誘導体
WO2024232832A1 (en) * 2023-05-11 2024-11-14 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound and related methods thereof
WO2025021942A1 (en) 2023-07-27 2025-01-30 Bracco Suisse Sa Ultrasound responsive vesicles containing lipid-polyamino acid conjugates
WO2025031991A1 (en) * 2023-08-04 2025-02-13 Polypeptide Therapeutic Solutions, S.L. Stealth-stabilized sulfur-containing lipo/polyamino acids
WO2025080209A1 (en) * 2023-10-10 2025-04-17 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound and related methods thereof
WO2025090023A1 (en) * 2023-10-24 2025-05-01 Agency For Science, Technology And Research A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound, and related methods thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0657722B2 (ja) * 1986-05-27 1994-08-03 三菱化成株式会社 水溶性ポリマ−組成物
US5149794A (en) * 1990-11-01 1992-09-22 State Of Oregon Covalent lipid-drug conjugates for drug targeting
US5395619A (en) * 1993-03-03 1995-03-07 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
US5972379A (en) * 1995-02-14 1999-10-26 Sequus Pharmaceuticals, Inc. Liposome composition and method for administering a quinolone
US6197332B1 (en) * 1997-08-13 2001-03-06 Chiron Corporation Lipid-conjugated polyamide compounds and related compositions and methods thereof
GB9811059D0 (en) * 1998-05-23 1998-07-22 Univ Strathclyde Polyamino acid vesicles
ATE416214T1 (de) * 2001-06-01 2008-12-15 Astellas Pharma Europ B V Zusammensetzungen enthaltend lipid-polymer konjugate

Also Published As

Publication number Publication date
US20040241222A1 (en) 2004-12-02
EE200300596A (et) 2004-02-16
ES2318027T3 (es) 2009-05-01
HUP0400171A2 (en) 2007-02-28
WO2002098951A3 (en) 2003-02-20
US20100145018A1 (en) 2010-06-10
HUP0400174A2 (en) 2007-02-28
PL367479A1 (en) 2005-02-21
EP1392756B1 (en) 2007-02-14
CN1308375C (zh) 2007-04-04
KR20040027512A (ko) 2004-04-01
CN1271116C (zh) 2006-08-23
DE60218154T2 (de) 2007-10-31
MXPA03011049A (es) 2004-06-25
ES2282439T3 (es) 2007-10-16
ZA200308937B (en) 2004-11-17
WO2002098951A2 (en) 2002-12-12
CZ20033480A3 (cs) 2004-07-14
CN1602326A (zh) 2005-03-30
EP1392755A1 (en) 2004-03-03
CA2448858A1 (en) 2002-12-12
DE60230137D1 (de) 2009-01-15
HRP20030976A2 (en) 2005-08-31
NO20035263D0 (no) 2003-11-27
SK15982003A3 (sk) 2004-06-08
ATE416214T1 (de) 2008-12-15
PL369455A1 (en) 2005-04-18
CZ20033479A3 (cs) 2004-07-14
ATE353927T1 (de) 2007-03-15
DE60218154D1 (de) 2007-03-29
KR100894852B1 (ko) 2009-04-24
JP2004527586A (ja) 2004-09-09
NO20035264D0 (no) 2003-11-27
BR0209695A (pt) 2005-01-11
MXPA03011050A (es) 2004-06-25
JP2004527585A (ja) 2004-09-09
HRP20030975A2 (en) 2005-08-31
KR20040027513A (ko) 2004-04-01
EP1392756A2 (en) 2004-03-03
US20040254352A1 (en) 2004-12-16
BR0209699A (pt) 2005-02-01
EP1392755B1 (en) 2008-12-03
CN1520435A (zh) 2004-08-11
CA2448856A1 (en) 2002-12-12
EE200300598A (et) 2004-02-16
SK15972003A3 (sk) 2004-06-08
ZA200308938B (en) 2004-11-17
WO2002098952A1 (en) 2002-12-12

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