ATE341554T1 - Cephemverbindungen und medikamente die diese verbindungen enthalten - Google Patents

Cephemverbindungen und medikamente die diese verbindungen enthalten

Info

Publication number
ATE341554T1
ATE341554T1 AT97914600T AT97914600T ATE341554T1 AT E341554 T1 ATE341554 T1 AT E341554T1 AT 97914600 T AT97914600 T AT 97914600T AT 97914600 T AT97914600 T AT 97914600T AT E341554 T1 ATE341554 T1 AT E341554T1
Authority
AT
Austria
Prior art keywords
optionally substituted
compounds
single bond
substituted lower
cephem
Prior art date
Application number
AT97914600T
Other languages
English (en)
Inventor
Yasuhiro Nishitani
Koji Ishikura
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE341554T1 publication Critical patent/ATE341554T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97914600T 1996-04-04 1997-04-04 Cephemverbindungen und medikamente die diese verbindungen enthalten ATE341554T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8253196 1996-04-04

Publications (1)

Publication Number Publication Date
ATE341554T1 true ATE341554T1 (de) 2006-10-15

Family

ID=13777098

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97914600T ATE341554T1 (de) 1996-04-04 1997-04-04 Cephemverbindungen und medikamente die diese verbindungen enthalten

Country Status (11)

Country Link
US (2) US6214818B1 (de)
EP (3) EP0893446B1 (de)
JP (1) JP4064462B2 (de)
KR (1) KR20000005238A (de)
CN (2) CN1088711C (de)
AT (1) ATE341554T1 (de)
AU (1) AU2178497A (de)
CA (1) CA2250002C (de)
DE (1) DE69736775T2 (de)
ES (1) ES2273364T3 (de)
WO (1) WO1997037996A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998022469A1 (fr) * 1996-11-22 1998-05-28 Meiji Seika Kaisha, Ltd. Intermediaires de cepheme et leur procede de production
EP1394159A1 (de) * 2002-08-13 2004-03-03 Warner-Lambert Company LLC Neue Thiophen-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
WO2006104141A1 (ja) * 2005-03-29 2006-10-05 Shionogi & Co., Ltd. ３－プロペニルセフェム誘導体
CA2658764A1 (en) * 2006-07-20 2008-01-24 Mehmet Kahraman Benzothiophene inhibitors of rho kinase
CN101153028B (zh) * 2006-09-30 2010-12-15 山东轩竹医药科技有限公司 具有抗菌抗病毒活性的化合物
UA115532C2 (uk) 2011-07-29 2017-11-27 Каріофарм Терапеутікс, Інк. Модулятори нуклеарного транспорту, що містять гідразид, і їхнє застосування
JP6006794B2 (ja) * 2011-07-29 2016-10-12 カリオファーム セラピューティクス，インコーポレイテッド 核内輸送調節因子およびその使用
WO2013036783A2 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
DK2858991T3 (en) 2012-05-09 2018-11-26 Biogen Ma Inc CELL NUCLEAR TRANSPORT MODULATORS AND APPLICATIONS THEREOF
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140274990A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US10202366B2 (en) 2013-03-15 2019-02-12 Karyopharm Therapeutics Inc. Methods of promoting wound healing using CRM1 inhibitors
MX2015012833A (es) 2013-03-15 2016-06-10 Merck Sharp & Dohme Composiciones antibioticas de ceftolozano.
WO2014205389A1 (en) 2013-06-21 2014-12-24 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
DK3180331T3 (da) 2014-08-15 2022-09-12 Karyopharm Therapeutics Inc Polymorfer af selinexor
MA43530A (fr) 2015-12-31 2018-11-07 Karyopharm Therapeutics Inc Modulateurs de transport nucléaire et leurs utilisations
WO2017117529A1 (en) 2015-12-31 2017-07-06 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
WO2018098472A1 (en) 2016-11-28 2018-05-31 Karyopharm Therapeutics Inc. Crm1 inhibitors for treating epilepsy

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5271239A (en) * 1975-12-10 1977-06-14 Matsushita Electric Ind Co Ltd Electron beam sensitive material
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3207840A1 (de) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"
JPS6064988A (ja) * 1983-09-21 1985-04-13 Sankyo Co Ltd セフアロスポリン誘導体
JPS60237090A (ja) * 1984-02-21 1985-11-25 Takeda Chem Ind Ltd セフエム化合物
GB8520155D0 (en) * 1985-08-10 1985-09-18 Beecham Group Plc Compounds
JPS62158290A (ja) * 1985-12-28 1987-07-14 Banyu Pharmaceut Co Ltd 新規セフアロスポリン誘導体
JPS62158291A (ja) * 1986-01-07 1987-07-14 Sagami Chem Res Center セフアロスポリン誘導体
JPH0459730A (ja) * 1990-06-26 1992-02-26 Dai Ichi Seiyaku Co Ltd セフェム系抗生物質含有凍結乾燥製剤
US5202321A (en) * 1991-06-13 1993-04-13 Merck Frosst Canada, Inc. Thiopyrano[2,3,4-c,d]indoles as inhibitors of leukotriene biosynthesis
JPH05217239A (ja) * 1991-10-31 1993-08-27 Sony Corp 光磁気ディスク記録再生装置
EP0554004A3 (en) * 1992-01-27 1993-11-24 Katayama Seisakusho Cephem compounds and antibacterial agents
JPH0741485A (ja) * 1993-07-30 1995-02-10 Katayama Seiyakushiyo:Kk セフェム誘導体およびそれを含有する抗菌剤

Also Published As

Publication number Publication date
US6214818B1 (en) 2001-04-10
CN1088711C (zh) 2002-08-07
EP1671966A1 (de) 2006-06-21
CA2250002C (en) 2008-03-25
EP0893446B1 (de) 2006-10-04
EP0893446A4 (de) 1999-01-27
CN1290702A (zh) 2001-04-11
EP0893446A1 (de) 1999-01-27
AU2178497A (en) 1997-10-29
CA2250002A1 (en) 1997-10-16
DE69736775T2 (de) 2007-08-23
EP1544197A1 (de) 2005-06-22
DE69736775D1 (de) 2006-11-16
WO1997037996A1 (fr) 1997-10-16
ES2273364T3 (es) 2007-05-01
KR20000005238A (ko) 2000-01-25
US6458950B1 (en) 2002-10-01
CN1129596C (zh) 2003-12-03
CN1215403A (zh) 1999-04-28
JP4064462B2 (ja) 2008-03-19

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Legal Events

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