ES8705363A1 - Un procedimiento para preparar derivados de tetrahidronaftaleno - Google Patents
Un procedimiento para preparar derivados de tetrahidronaftalenoInfo
- Publication number
- ES8705363A1 ES8705363A1 ES552087A ES552087A ES8705363A1 ES 8705363 A1 ES8705363 A1 ES 8705363A1 ES 552087 A ES552087 A ES 552087A ES 552087 A ES552087 A ES 552087A ES 8705363 A1 ES8705363 A1 ES 8705363A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- hypertension
- treatment
- alkyl
- tetrahydronaphthalenols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE TETRAHIDRONAFTALENO. CONSISTE EN HACER REACCIONAR EL ISOMERO CIS DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER DERIVADOS DE TETRAHIDRONAFTALENO DE FORMULA (I) DONDE R1 ES H O METILO; R3 Y R4 SON CADA UNO ARILO O CICLOALQUILO, O R3 ES H O ALQUILO Y R4 ES CICLOALQUILO O 9H-FLUOREN-9-ILO, O R3 ES H O ALQUILO Y R4 ES HETEROARILO; R5 Y R6 SON IGUALES O DIFERENTES Y SON CADA UNO H, HIDROXI, ALCOXI O ALCANOILO; Y N ES 1, 2, 3 O 4. TIENEN APLICACIONES FARMACOLOGICAS PARA DISMINUIR LA TENSION SANGUINEA DE UN HUESPED HIPERTENSO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61125884A | 1984-05-17 | 1984-05-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8705363A1 true ES8705363A1 (es) | 1987-05-01 |
ES552087A0 ES552087A0 (es) | 1987-05-01 |
Family
ID=24448300
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543242A Expired ES8701144A1 (es) | 1984-05-17 | 1985-05-17 | Un procedimiento para preparar un derivado de tetrahidronaf-taleno |
ES552087A Expired ES8705363A1 (es) | 1984-05-17 | 1986-02-17 | Un procedimiento para preparar derivados de tetrahidronaftaleno |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543242A Expired ES8701144A1 (es) | 1984-05-17 | 1985-05-17 | Un procedimiento para preparar un derivado de tetrahidronaf-taleno |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0163458A1 (es) |
JP (1) | JPS60260546A (es) |
KR (1) | KR910002944B1 (es) |
AU (1) | AU573828B2 (es) |
DK (1) | DK219885A (es) |
ES (2) | ES8701144A1 (es) |
FI (1) | FI851969L (es) |
GR (1) | GR851204B (es) |
HU (1) | HUT38298A (es) |
IL (1) | IL75224A (es) |
NZ (1) | NZ212112A (es) |
PT (1) | PT80481B (es) |
ZA (1) | ZA853759B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0254989B1 (en) * | 1986-07-28 | 1990-09-26 | Whitby Research Incorporated | Substituted 2-aminotetralins |
FR2719587B1 (fr) * | 1994-05-03 | 1996-07-12 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4267373A (en) * | 1972-07-03 | 1981-05-12 | E. R. Squibb & Sons, Inc. | 5,6,7,8-Tetrahydronaphthalene hypotensive agents |
US3930022A (en) * | 1972-07-03 | 1975-12-30 | Squibb & Sons Inc | Certain tetrahydronaphthalenes used in the treatment of cardiac arrhythmia |
GB1442851A (en) * | 1973-07-09 | 1976-07-14 | Squibb & Sons Inc | Substituted cyclic polymethylene phenols |
AU8194275A (en) * | 1974-06-17 | 1976-12-16 | Takeda Chemical Industries Ltd | Aminotetralin compounds |
IL65501A (en) * | 1981-05-08 | 1986-04-29 | Astra Laekemedel Ab | 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them |
NZ213651A (en) * | 1984-10-11 | 1989-07-27 | Hoffmann La Roche | Tetrahydronapthalene derivatives and medicaments |
-
1985
- 1985-05-16 AU AU42547/85A patent/AU573828B2/en not_active Expired - Fee Related
- 1985-05-17 FI FI851969A patent/FI851969L/fi not_active Application Discontinuation
- 1985-05-17 ZA ZA853759A patent/ZA853759B/xx unknown
- 1985-05-17 GR GR851204A patent/GR851204B/el unknown
- 1985-05-17 HU HU851872A patent/HUT38298A/hu unknown
- 1985-05-17 IL IL75224A patent/IL75224A/xx unknown
- 1985-05-17 EP EP85303472A patent/EP0163458A1/en not_active Ceased
- 1985-05-17 PT PT80481A patent/PT80481B/pt not_active IP Right Cessation
- 1985-05-17 ES ES543242A patent/ES8701144A1/es not_active Expired
- 1985-05-17 DK DK219885A patent/DK219885A/da unknown
- 1985-05-17 KR KR1019850003375A patent/KR910002944B1/ko active IP Right Grant
- 1985-05-17 JP JP60106806A patent/JPS60260546A/ja active Pending
- 1985-05-17 NZ NZ212112A patent/NZ212112A/xx unknown
-
1986
- 1986-02-17 ES ES552087A patent/ES8705363A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL75224A0 (en) | 1985-09-29 |
AU4254785A (en) | 1985-11-21 |
ES543242A0 (es) | 1986-11-16 |
FI851969A0 (fi) | 1985-05-17 |
PT80481B (en) | 1987-01-15 |
JPS60260546A (ja) | 1985-12-23 |
KR850008659A (ko) | 1985-12-21 |
PT80481A (en) | 1985-06-01 |
FI851969L (fi) | 1985-11-18 |
AU573828B2 (en) | 1988-06-23 |
ZA853759B (en) | 1986-01-29 |
HUT38298A (en) | 1986-05-28 |
NZ212112A (en) | 1988-10-28 |
KR910002944B1 (ko) | 1991-05-11 |
EP0163458A1 (en) | 1985-12-04 |
DK219885D0 (da) | 1985-05-17 |
IL75224A (en) | 1988-11-15 |
ES552087A0 (es) | 1987-05-01 |
GR851204B (es) | 1985-11-25 |
DK219885A (da) | 1985-11-18 |
ES8701144A1 (es) | 1986-11-16 |
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