ATE334128T1 - Neue chinuclidinderivate und medizinische zusammensetzungen, die diese verbindungen enthalten - Google Patents

Neue chinuclidinderivate und medizinische zusammensetzungen, die diese verbindungen enthalten

Info

Publication number
ATE334128T1
ATE334128T1 AT01986924T AT01986924T ATE334128T1 AT E334128 T1 ATE334128 T1 AT E334128T1 AT 01986924 T AT01986924 T AT 01986924T AT 01986924 T AT01986924 T AT 01986924T AT E334128 T1 ATE334128 T1 AT E334128T1
Authority
AT
Austria
Prior art keywords
quinuclidene
derivatives
compounds
new
compositions containing
Prior art date
Application number
AT01986924T
Other languages
English (en)
Inventor
Quinones Maria Prat
Forner Maria Dolors Fernandez
Albero Maria Antonia Buil
Original Assignee
Almirall Prodesfarma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma Ag filed Critical Almirall Prodesfarma Ag
Application granted granted Critical
Publication of ATE334128T1 publication Critical patent/ATE334128T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01986924T 2000-12-28 2001-12-20 Neue chinuclidinderivate und medizinische zusammensetzungen, die diese verbindungen enthalten ATE334128T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200003130 2000-12-28

Publications (1)

Publication Number Publication Date
ATE334128T1 true ATE334128T1 (de) 2006-08-15

Family

ID=8496180

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01986924T ATE334128T1 (de) 2000-12-28 2001-12-20 Neue chinuclidinderivate und medizinische zusammensetzungen, die diese verbindungen enthalten

Country Status (33)

Country Link
US (4) US7122558B2 (de)
EP (1) EP1353919B1 (de)
JP (1) JP4295985B2 (de)
KR (1) KR100869721B1 (de)
CN (1) CN1250545C (de)
AR (1) AR032072A1 (de)
AT (1) ATE334128T1 (de)
AU (1) AU2002238471B2 (de)
BG (1) BG66162B1 (de)
BR (1) BR0116624A (de)
CA (1) CA2433128C (de)
CY (1) CY1105719T1 (de)
CZ (1) CZ301209B6 (de)
DE (1) DE60121813T2 (de)
DK (1) DK1353919T3 (de)
EC (1) ECSP034672A (de)
EE (1) EE05404B1 (de)
ES (1) ES2266291T3 (de)
HU (1) HUP0303524A3 (de)
IL (2) IL156558A0 (de)
MX (1) MXPA03005862A (de)
MY (1) MY136067A (de)
NO (1) NO328772B1 (de)
NZ (1) NZ526674A (de)
PE (1) PE20020721A1 (de)
PL (1) PL363807A1 (de)
PT (1) PT1353919E (de)
RU (1) RU2282629C2 (de)
SI (1) SI1353919T1 (de)
SK (1) SK287414B6 (de)
UA (1) UA75626C2 (de)
WO (1) WO2002053564A2 (de)
ZA (1) ZA200305008B (de)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
HUP0303529A3 (en) 2000-12-22 2008-03-28 Almirall Ag New quinuclidine carbamate derivatives, process for their preparation and pharmaceutical compositions containing them and their use
CN1250545C (zh) * 2000-12-28 2006-04-12 阿尔米雷尔普罗迪斯制药有限公司 新的奎宁环衍生物类及含有这类衍生物的药物组合物
GB0118373D0 (en) * 2001-07-27 2001-09-19 Glaxo Group Ltd Novel therapeutic method
ES2203327B1 (es) 2002-06-21 2005-06-16 Almirall Prodesfarma, S.A. Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen.
ES2204295B1 (es) 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
NZ537584A (en) * 2002-07-08 2006-07-28 Ranbaxy Lab Ltd 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists
AU2002321711A1 (en) * 2002-08-09 2004-02-25 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives useful as muscarinic receptor antagonist
TW200800953A (en) 2002-10-30 2008-01-01 Theravance Inc Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
WO2004089898A1 (en) 2003-04-09 2004-10-21 Ranbaxy Laboratories Limited Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
BRPI0409302A (pt) * 2003-04-11 2006-04-11 Ranbaxy Lab Ltd derivados azabiciclo como antagonistas de recetores muscarìnicos, método para sua preparação e composição farmacêutica contendo os mesmos
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.
AR044519A1 (es) 2003-05-02 2005-09-14 Novartis Ag Derivados de piridin-tiazol amina y de pirimidin-tiazol amina
CN100445281C (zh) * 2003-05-02 2008-12-24 诺瓦提斯公司 与毒蕈碱性m3受体结合的奎宁环衍生物
ATE435862T1 (de) 2003-05-28 2009-07-15 Theravance Inc Azabicycloalkanverbindungen als muscarinrezeptor antagonisten
JP2007524641A (ja) 2003-07-11 2007-08-30 セラヴァンス, インコーポレーテッド 置換4−アミノ−1−ベンジルピペリジン化合物
US20050026887A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a steroid
GB0401334D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
ES2239546B1 (es) * 2004-03-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos esteres de quinuclidina cuaternizados.
UY28871A1 (es) 2004-04-27 2005-11-30 Glaxo Group Ltd Antagonistas del receptor de acetilcolina muscarinico
EP1747219A4 (de) * 2004-05-13 2010-05-26 Glaxo Group Ltd Antagonisten des muscarinischen acetylcholinrezeptors
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
NZ551669A (en) * 2004-05-31 2010-07-30 Almirall Lab Combinations comprising antimuscarinic agents and PDE4 inhibitors
WO2006035303A1 (en) * 2004-09-29 2006-04-06 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
MX2007004976A (es) * 2004-10-25 2007-06-14 Schering Corp Antagonistas de receptor m1 y/o m3 en combinacion con otros compuestos activos para tratar trastornos respiratorios.
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
WO2007045979A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
US7910708B2 (en) 2005-10-21 2011-03-22 Novartis Ag Anti-IL13 human antibodies
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
ATE549337T1 (de) 2006-04-21 2012-03-15 Novartis Ag Purinderivate zur verwendung als adenosin-a2a- rezeptoragonisten
ES2298049B1 (es) * 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
KR20090073121A (ko) 2006-09-29 2009-07-02 노파르티스 아게 Pi3k 지질 키나제 억제제로서의 피라졸로피리미딘
TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
RS51644B (sr) 2007-01-10 2011-10-31 Irm Llc. Jedinjenja i preparati kao inhibitori kanal aktivirajuće proteaze
BRPI0806972A2 (pt) * 2007-02-09 2014-04-08 Astellas Pharma Inc Composto cíclico contendo ponte azo
TW200843759A (en) * 2007-02-15 2008-11-16 Argenta Discovery Ltd Compounds and their use II
KR20100005730A (ko) 2007-05-07 2010-01-15 노파르티스 아게 유기 화합물
JP5656288B2 (ja) 2007-09-07 2015-01-21 セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー ムスカリン受容体アンタゴニストとして有用なグアジニン含有化合物
CA2608561A1 (en) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Motorcycle wind deflector accessory support
EA017919B1 (ru) 2007-12-10 2013-04-30 Новартис Аг Производные пиразин-2-карбоксамида для лечения заболеваний, которые поддаются лечению путем блокирования эпителиальных натриевых каналов
US8017617B2 (en) * 2007-12-14 2011-09-13 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
EP2231642B1 (de) 2008-01-11 2013-10-23 Novartis AG Pyrimidine als kinasehemmer
EP2100598A1 (de) * 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
EP2100599A1 (de) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung
US8268834B2 (en) 2008-03-19 2012-09-18 Novartis Ag Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
GB0808708D0 (en) * 2008-05-13 2008-06-18 Astrazeneca Ab New compounds 274
GB0808707D0 (en) * 2008-05-13 2008-06-18 Argenta Discovery Ltd New compounds 275
NZ589091A (en) 2008-05-13 2011-07-29 Astrazeneca Ab Quinuclidine derivatives as muscarinic m3 receptor antagonists
KR20110040818A (ko) 2008-06-10 2011-04-20 노파르티스 아게 상피 나트륨 채널 차단제로서의 피라진 유도체
US8263623B2 (en) 2008-07-11 2012-09-11 Pfizer Inc. Triazol derivatives useful for the treatment of diseases
GB0814729D0 (en) * 2008-08-12 2008-09-17 Argenta Discovery Ltd New combination
PL2391366T3 (pl) 2009-01-29 2013-04-30 Novartis Ag Podstawione benzimidazole do leczenia gwiaździaków
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
EA201200260A1 (ru) 2009-08-12 2012-09-28 Новартис Аг Гетероциклические гидразоны и их применение для лечения рака и воспаления
MY162604A (en) 2009-08-17 2017-06-30 Intellikine Llc Heterocyclic compounds and uses thereof
MX2012002179A (es) 2009-08-20 2012-03-16 Novartis Ag Compuestos heterociclicos de oxima.
EP2813227A1 (de) 2009-10-22 2014-12-17 Vertex Pharmaceuticals Incorporated Zusammensetzungen für die Behandlung von Mukoviszidose und anderen chronischen Erkrankungen
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
EP2386555A1 (de) 2010-05-13 2011-11-16 Almirall, S.A. Neue Cyclohexylaminderivate mit Aktivitäten von Beta2-adrenergem Agonisten und M3-Muskarin-Antagonisten
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
JP2014505088A (ja) 2011-02-10 2014-02-27 ノバルティス アーゲー C−METチロシンキナーゼ阻害剤としての[1,2,4]トリアゾロ[4,3−b]ピリダジン化合物
EP2678016B1 (de) 2011-02-23 2016-08-10 Intellikine, LLC Heterocyclische verbindungen und ihre verwendung
AU2012220572A1 (en) 2011-02-25 2013-08-29 Irm Llc Compounds and compositions as trk inhibitors
EP2510928A1 (de) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten
US8883819B2 (en) 2011-09-01 2014-11-11 Irm Llc Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
UY34329A (es) 2011-09-15 2013-04-30 Novartis Ag Compuestos de triazolopiridina
WO2013038378A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038373A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
ES2882807T3 (es) 2011-09-16 2021-12-02 Novartis Ag Heterociclil carboxamidas N-sustituidas
WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
WO2013038386A1 (en) 2011-09-16 2013-03-21 Novartis Ag Heterocyclic compounds for the treatment of cystic fibrosis
US20130209543A1 (en) 2011-11-23 2013-08-15 Intellikine Llc Enhanced treatment regimens using mtor inhibitors
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
CN110507654A (zh) 2012-04-03 2019-11-29 诺华有限公司 有酪氨酸激酶抑制剂的组合产品和其应用
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
EP2968340A4 (de) 2013-03-15 2016-08-10 Intellikine Llc Kombination von kinaseinhibitoren und verwendungen davon
CN105431432B (zh) * 2013-07-13 2018-01-09 北京硕佰医药科技有限责任公司 奎宁类化合物、其光学异构体及其制备方法和医药用途
WO2015084804A1 (en) 2013-12-03 2015-06-11 Novartis Ag Combination of mdm2 inhibitor and braf inhibitor and their use
PL3134395T3 (pl) 2014-04-24 2018-07-31 Novartis Ag Pochodne pirazyny jako inhibitory 3-kinazy fosfatydyloinozytolu
EP3134397A1 (de) 2014-04-24 2017-03-01 Novartis AG Aminopyrazinderivate als phosphatidylinositol-3-kinasehemmer
US10112926B2 (en) 2014-04-24 2018-10-30 Novartis Ag Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors
WO2016011658A1 (en) 2014-07-25 2016-01-28 Novartis Ag Combination therapy
KR20170036037A (ko) 2014-07-31 2017-03-31 노파르티스 아게 조합 요법
EP3980121A1 (de) 2019-06-10 2022-04-13 Novartis AG Pyridin- und pyrazinderivate zur behandlung von cf, copd und bronchiektasie
PH12022550468A1 (en) 2019-08-28 2023-03-06 Novartis Ag Substituted 1,3-phenyl heteroaryl derivatives and their use in the treatment of disease
TW202140550A (zh) 2020-01-29 2021-11-01 瑞士商諾華公司 使用抗tslp抗體治療炎性或阻塞性氣道疾病之方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4465834A (en) * 1965-09-20 1984-08-14 Fmc Corporation Anticholinergic drugs
GB1219606A (en) 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4082756A (en) 1971-04-16 1978-04-04 Colgate-Palmolive Company Quaternary quinuclidinium carbamates and thiocarbamates
JPS57500735A (de) * 1980-06-03 1982-04-30
US4431627A (en) 1980-06-03 1984-02-14 Research Corporation Gamma-emitting receptor-binding 3-quinuclidinyl glycolates; methods of preparation thereof and imaging and assay methods utilizing same
FR2539135B1 (fr) * 1983-01-11 1986-02-28 Essilor Int Hydrogels de polyurethane et procede de fabrication
IL72788A (en) * 1984-08-28 1989-07-31 Israel State Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them
US4644003A (en) * 1985-04-03 1987-02-17 Research Corporation 3-quinuclidinol esters, useful as antagonists of muscarinic acetylcholine receptors
US4675326A (en) * 1985-05-08 1987-06-23 Gabriel Amitai Bisquaternary antidotes
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
IT1230881B (it) * 1989-06-20 1991-11-08 Angeli Inst Spa Derivati del r(-) 3-chinuclidinolo
DE3931041C2 (de) 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
GB8923590D0 (en) 1989-10-19 1989-12-06 Pfizer Ltd Antimuscarinic bronchodilators
CA2073005C (en) * 1990-09-06 1998-11-10 Alan Stobie Antimuscarinic bronchodilators
DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln
GB9119705D0 (en) 1991-09-14 1991-10-30 Pfizer Ltd Therapeutic compounds
WO1995021820A1 (en) 1994-02-10 1995-08-17 Yamanouchi Pharmaceutical Co., Ltd. Novel carbamate derivative and medicinal composition containing the same
NO2005012I1 (no) 1994-12-28 2005-06-06 Debio Rech Pharma Sa Triptorelin og farmasoytisk akseptable salter derav
DE69615214T2 (de) * 1995-10-13 2002-06-27 Banyu Pharmaceutical Co., Ltd. Substituierte heteroaromatische derivate
PE92198A1 (es) * 1996-08-01 1999-01-09 Banyu Pharma Co Ltd Derivados de 1,4-piperidina disustituida que contienen fluor
US7214687B2 (en) * 1999-07-14 2007-05-08 Almirall Ag Quinuclidine derivatives and medicinal compositions containing the same
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
AU6610001A (en) 2000-06-27 2002-01-08 S A L V A T Lab Sa Carbamates derived from arylalkylamines
HUP0303529A3 (en) * 2000-12-22 2008-03-28 Almirall Ag New quinuclidine carbamate derivatives, process for their preparation and pharmaceutical compositions containing them and their use
CN1250545C (zh) * 2000-12-28 2006-04-12 阿尔米雷尔普罗迪斯制药有限公司 新的奎宁环衍生物类及含有这类衍生物的药物组合物

Also Published As

Publication number Publication date
KR100869721B1 (ko) 2008-11-21
BR0116624A (pt) 2003-12-23
CA2433128A1 (en) 2002-07-11
NZ526674A (en) 2005-03-24
EE200300312A (et) 2003-10-15
NO20033002D0 (no) 2003-06-30
WO2002053564A3 (en) 2002-10-31
SK287414B6 (sk) 2010-09-07
ZA200305008B (en) 2005-01-26
JP2004517123A (ja) 2004-06-10
AU2002238471B2 (en) 2007-06-28
US7893087B2 (en) 2011-02-22
EE05404B1 (et) 2011-04-15
IL156558A (en) 2009-06-15
HUP0303524A3 (en) 2008-03-28
HK1055739A1 (en) 2004-01-21
ECSP034672A (es) 2003-08-29
KR20030067726A (ko) 2003-08-14
CA2433128C (en) 2010-05-25
CY1105719T1 (el) 2010-12-22
BG66162B1 (bg) 2011-09-30
RU2282629C2 (ru) 2006-08-27
US20070105897A1 (en) 2007-05-10
MXPA03005862A (es) 2005-09-08
UA75626C2 (en) 2006-05-15
PE20020721A1 (es) 2002-10-01
DE60121813D1 (de) 2006-09-07
US20070129398A1 (en) 2007-06-07
HUP0303524A2 (hu) 2004-01-28
CZ20031812A3 (en) 2004-05-12
SI1353919T1 (sl) 2006-12-31
IL156558A0 (en) 2004-01-04
NO328772B1 (no) 2010-05-10
AR032072A1 (es) 2003-10-22
MY136067A (en) 2008-08-29
DK1353919T3 (da) 2006-11-20
PT1353919E (pt) 2006-11-30
BG107950A (bg) 2004-03-31
CN1487938A (zh) 2004-04-07
NO20033002L (no) 2003-06-30
US20100234332A1 (en) 2010-09-16
US7879874B2 (en) 2011-02-01
US7122558B2 (en) 2006-10-17
EP1353919B1 (de) 2006-07-26
PL363807A1 (en) 2004-11-29
CN1250545C (zh) 2006-04-12
WO2002053564A2 (en) 2002-07-11
JP4295985B2 (ja) 2009-07-15
DE60121813T2 (de) 2007-09-20
EP1353919A2 (de) 2003-10-22
ES2266291T3 (es) 2007-03-01
US20040072863A1 (en) 2004-04-15
RU2003123120A (ru) 2005-01-10
SK7992003A3 (en) 2004-08-03
CZ301209B6 (cs) 2009-12-09

Similar Documents

Publication Publication Date Title
DE60121813D1 (de) Neue chinuclidinderivate und medizinische zusammensetzungen, die diese verbindungen enthalten
ATE335753T1 (de) Glucopyranosyloxybenzylbenzol derivate und medizinische zusammensetzungen, die diese verbindungen enthalten
ATE267161T1 (de) Phenoxyessigsäure-verbindungen und medizinische zusammensetzungen, die diese enthalten
ATE337311T1 (de) Heterocyclylalkylpiperidinderivate, deren herstellung und zusammensetzungen, die diese derivate enthalten
ATE453391T1 (de) Östrogene mittel enthaltende arzneizusammensetzungen
DE69424173D1 (de) Carbodiimide-Verbindungen und dauerhafte wasserabweisende Zusammensetzungen, die diese Verbindungen enthalten
EP1126838A4 (de) Nitrosierte und nitrosylierte nichtsteroidale antiphlogistishe verbindungen, zusammenstellungen und verwendungsmethoden
ID28695A (id) TURUNAN-TURUNAN BENZO (b) TIEPIN 1,1-DIOKSIDA, PROSES PENYIAPAN, SEDIAAN FARMASI YANG MENGANDUNG SENYAWA-SENYAWA INI, DAN PENGGUNAANNYA
ATE353909T1 (de) 3-stickstoff-6,7-dioxygenierte steroid verbindungen und verwendungen davon
DE60211532D1 (de) Pastöse zusammensetzung und diese enthaltende kosmetika
ATE271562T1 (de) Neue verbindungen der familie von n- acylaminoamiden, sie enthaltende zusammensetzungen und verwendungen
DE60117859D1 (de) HARNSTOFFSUBSTITUIERTE IMIDAZOCHINOLINETHER und Arzneimittel, die diese umfassen.
ATE298748T1 (de) (1,4')-bipiperidin verbindungen
DE60209929D1 (de) Succinate des 5,8,14-triazatetracycloä10.3.1.0 2,11 .0 4,9 ü-hexadeca-2(11),3,5,7,9,-pentaens und pharmazeutische zusammensetzungen
ATE264841T1 (de) Indol-derivate und medizinische zusammensetzungen die diese enthalten
EE200200281A (et) Pikornaviirusevastased ühendid ja kompositsioonid, nende farmatseutilised kasutusalad ning ained nende sünteesiks
DE59900969D1 (de) Neue Diaminobenzol-Derivate und diese Verbindungen enthaltende Färbemittel
DE60012988D1 (en) Taxane mit carbonaten in c-4
ATE250570T1 (de) Phenylaminoalkylcarbonsäure-derivate und medizinische zusammensetzungen, die diese enthalten
ATE529419T1 (de) Chromanderivate als estrogene verbindungen
DE60042585D1 (de) 3-Aza-6,8-dioxabicycloÄ3.2.1Üoctane und Analoga sowie diese enthaltende kombinatorische Bibliotheken
ITMI20011637A0 (it) Composizione farmaceutica contenente citalopram
ATE277006T1 (de) (poly)thia-alkin-verbindungen und ihre derivate, diese enthaltende zusammensetzungen und ihre anwendung
DE60134735D1 (de) Neue neurokinin-antagonisten zum gebrauch als arzneimittel
DE60005517D1 (de) Kaliumkanal-blockierende mittel

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1353919

Country of ref document: EP

EEFA Change of the company name
EEIH Change in the person of patent owner