IL72788A - Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them - Google Patents

Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them

Info

Publication number
IL72788A
IL72788A IL72788A IL7278884A IL72788A IL 72788 A IL72788 A IL 72788A IL 72788 A IL72788 A IL 72788A IL 7278884 A IL7278884 A IL 7278884A IL 72788 A IL72788 A IL 72788A
Authority
IL
Israel
Prior art keywords
bis
quinuclidines
piperidines
pyridines
trimethylene
Prior art date
Application number
IL72788A
Other versions
IL72788A0 (en
Inventor
Amitai Gabriel
Balderman David
Brukstein Rachel
Spiegelstein Michael
Original Assignee
Israel State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Israel State filed Critical Israel State
Priority to IL72788A priority Critical patent/IL72788A/en
Publication of IL72788A0 publication Critical patent/IL72788A0/en
Priority to FR8512700A priority patent/FR2571053B1/en
Priority to CA000489417A priority patent/CA1283412C/en
Publication of IL72788A publication Critical patent/IL72788A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
IL72788A 1984-08-28 1984-08-28 Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them IL72788A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL72788A IL72788A (en) 1984-08-28 1984-08-28 Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them
FR8512700A FR2571053B1 (en) 1984-08-28 1985-08-26 NOVEL QUATERNARY AMMONIUM COMPOUNDS, THEIR PREPARATION AND APPLICATIONS
CA000489417A CA1283412C (en) 1984-08-28 1985-08-26 Antidotes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL72788A IL72788A (en) 1984-08-28 1984-08-28 Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them

Publications (2)

Publication Number Publication Date
IL72788A0 IL72788A0 (en) 1984-11-30
IL72788A true IL72788A (en) 1989-07-31

Family

ID=11055287

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72788A IL72788A (en) 1984-08-28 1984-08-28 Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them

Country Status (3)

Country Link
CA (1) CA1283412C (en)
FR (1) FR2571053B1 (en)
IL (1) IL72788A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235878A3 (en) * 1986-01-16 1989-06-14 Beecham Group Plc Novel compounds
MXPA03005583A (en) 2000-12-22 2004-05-05 Almirall Prodesfarma Ag Quinuclidine carbamate derivatives and their use as m3 antagonists.
KR100869721B1 (en) * 2000-12-28 2008-11-21 알미랄 에이쥐 Novel quinuclidine derivatives and medicinal compositions containing the same
ES2204295B1 (en) 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. NEW DERIVATIVES OF QUINUCLIDINE-AMIDE.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2834779A (en) * 1956-12-11 1958-05-13 Lakeside Lab Inc Disubstituted aminoalkyl quinuclidinium derivatives
US3135761A (en) * 1959-04-28 1964-06-02 Jr Brennie E Hackley Bis quaternary oximes
US3077476A (en) * 1959-04-28 1963-02-12 Jr Brennie E Hackley Bis quaternary oximes
DE1670672A1 (en) * 1966-02-18 1970-12-03 Merck Patent Gmbh Bis-quaternary pyridinium salts and processes for their preparation
US3919240A (en) * 1966-08-17 1975-11-11 Harold Z Sommer Quaternary quinuclidinones
DE1670208A1 (en) * 1967-04-01 1971-02-25 Albert Scherer Process for the preparation of unsymmetrical bispyridinium salts of bishalogen methyl ethers
US3852294A (en) * 1968-08-27 1974-12-03 Merck Patent Gmbh Bis-quaternary pyridinium salts
DE2616481A1 (en) * 1976-04-14 1977-11-03 Merck Patent Gmbh BIS-QUARTAERE PYRIDINIUM-2-ALDOXIM SALT AND THE PROCESS FOR THEIR PRODUCTION

Also Published As

Publication number Publication date
FR2571053A1 (en) 1986-04-04
IL72788A0 (en) 1984-11-30
CA1283412C (en) 1991-04-23
FR2571053B1 (en) 1988-12-02

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Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees