ATE333274T1 - Verwendung von l-acetylcarnitin in kombination mit biotin zur behandlung von patienten mit insulinresistentem diabetes mellitus typ ii - Google Patents

Verwendung von l-acetylcarnitin in kombination mit biotin zur behandlung von patienten mit insulinresistentem diabetes mellitus typ ii

Info

Publication number
ATE333274T1
ATE333274T1 AT02741155T AT02741155T ATE333274T1 AT E333274 T1 ATE333274 T1 AT E333274T1 AT 02741155 T AT02741155 T AT 02741155T AT 02741155 T AT02741155 T AT 02741155T AT E333274 T1 ATE333274 T1 AT E333274T1
Authority
AT
Austria
Prior art keywords
biotin
patients
treatment
diabetes mellitus
acetylcarnitine
Prior art date
Application number
AT02741155T
Other languages
English (en)
Inventor
Menotti Calvani
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of ATE333274T1 publication Critical patent/ATE333274T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02741155T 2001-05-29 2002-05-24 Verwendung von l-acetylcarnitin in kombination mit biotin zur behandlung von patienten mit insulinresistentem diabetes mellitus typ ii ATE333274T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001RM000294A ITRM20010294A1 (it) 2001-05-29 2001-05-29 Uso della acetil l-carnetina in associazione con la biotina per il trattamento di pazienti affetti da diabete mellito di tipo ii insulino re

Publications (1)

Publication Number Publication Date
ATE333274T1 true ATE333274T1 (de) 2006-08-15

Family

ID=11455558

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02741155T ATE333274T1 (de) 2001-05-29 2002-05-24 Verwendung von l-acetylcarnitin in kombination mit biotin zur behandlung von patienten mit insulinresistentem diabetes mellitus typ ii

Country Status (18)

Country Link
US (2) US20040142879A1 (de)
EP (1) EP1399142B1 (de)
JP (1) JP4381685B2 (de)
KR (1) KR20040010666A (de)
AT (1) ATE333274T1 (de)
CA (1) CA2448244C (de)
CY (1) CY1105403T1 (de)
CZ (1) CZ297743B6 (de)
DE (1) DE60213237T2 (de)
DK (1) DK1399142T3 (de)
ES (1) ES2268053T3 (de)
HU (1) HUP0400060A2 (de)
IT (1) ITRM20010294A1 (de)
MX (1) MXPA03010921A (de)
PL (1) PL207522B1 (de)
PT (1) PT1399142E (de)
SK (1) SK287832B6 (de)
WO (1) WO2002096410A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK287787B6 (sk) * 2000-12-15 2011-09-05 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Použitie L-karnitínu ako stabilizačného činidla proteínov
ITRM20040327A1 (it) * 2004-07-01 2004-10-01 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.
US8569366B2 (en) * 2005-04-26 2013-10-29 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes
EP1832295A1 (de) * 2006-03-10 2007-09-12 Tecnogen S.P.A. Verwendung von PTX3 zur Behandlung viraler Erkrankungen
WO2008113862A2 (en) * 2007-03-21 2008-09-25 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition useful for the prevention of type 2 diabetes and its complications in pre-diabetic patients with insulin resistance
GB201304112D0 (en) * 2013-03-07 2013-04-24 Univ Nottingham Modulation of energy expenditure

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196564B (it) * 1986-08-04 1988-11-16 Sigma Tau Ind Farmaceuti Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
US6020139A (en) * 1995-04-25 2000-02-01 Oridigm Corporation S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy
US5789401A (en) * 1997-08-08 1998-08-04 Nutrition 21 High-dose chromium/biotin treatment of type II diabetes

Also Published As

Publication number Publication date
CZ20033221A3 (cs) 2004-06-16
DE60213237T2 (de) 2007-08-02
US20080269307A1 (en) 2008-10-30
CA2448244A1 (en) 2002-12-05
CY1105403T1 (el) 2010-04-28
DE60213237D1 (de) 2006-08-31
PT1399142E (pt) 2006-10-31
SK15852003A3 (sk) 2004-04-06
PL367630A1 (en) 2005-03-07
US8053472B2 (en) 2011-11-08
ITRM20010294A0 (it) 2001-05-29
JP2004532866A (ja) 2004-10-28
EP1399142B1 (de) 2006-07-19
ITRM20010294A1 (it) 2002-11-29
SK287832B6 (sk) 2011-11-04
MXPA03010921A (es) 2004-02-27
CZ297743B6 (cs) 2007-03-21
WO2002096410A1 (en) 2002-12-05
US20040142879A1 (en) 2004-07-22
ES2268053T3 (es) 2007-03-16
HUP0400060A2 (hu) 2004-04-28
JP4381685B2 (ja) 2009-12-09
PL207522B1 (pl) 2010-12-31
DK1399142T3 (da) 2006-10-30
EP1399142A1 (de) 2004-03-24
KR20040010666A (ko) 2004-01-31
CA2448244C (en) 2010-11-02

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