ATE329930T1 - Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln - Google Patents

Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln

Info

Publication number
ATE329930T1
ATE329930T1 AT02774712T AT02774712T ATE329930T1 AT E329930 T1 ATE329930 T1 AT E329930T1 AT 02774712 T AT02774712 T AT 02774712T AT 02774712 T AT02774712 T AT 02774712T AT E329930 T1 ATE329930 T1 AT E329930T1
Authority
AT
Austria
Prior art keywords
sialylation
production
medicinal products
high degrees
fsh compositions
Prior art date
Application number
AT02774712T
Other languages
English (en)
Inventor
Ernest Loumaye
Carlo Emanuele Giartosio
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23323355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE329930(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of ATE329930T1 publication Critical patent/ATE329930T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02774712T 2001-10-22 2002-10-15 Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln ATE329930T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33808801P 2001-10-22 2001-10-22

Publications (1)

Publication Number Publication Date
ATE329930T1 true ATE329930T1 (de) 2006-07-15

Family

ID=23323355

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02774712T ATE329930T1 (de) 2001-10-22 2002-10-15 Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln

Country Status (24)

Country Link
US (1) US20050085412A1 (de)
EP (2) EP1621549A3 (de)
JP (1) JP2005515974A (de)
KR (1) KR100929971B1 (de)
CN (1) CN1608078B (de)
AR (1) AR036926A1 (de)
AT (1) ATE329930T1 (de)
AU (1) AU2002340562B2 (de)
CA (1) CA2464368A1 (de)
DE (1) DE60212425T2 (de)
DK (1) DK1438336T3 (de)
EA (1) EA007030B1 (de)
ES (1) ES2261740T3 (de)
HR (1) HRP20040278B1 (de)
IL (2) IL161235A0 (de)
ME (1) MEP38608A (de)
MX (1) MXPA04003352A (de)
NO (1) NO327966B1 (de)
PL (1) PL369606A1 (de)
PT (1) PT1438336E (de)
RS (1) RS32804A (de)
UA (1) UA87433C2 (de)
WO (1) WO2003035686A2 (de)
ZA (1) ZA200402279B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0524782D0 (en) * 2005-12-05 2006-01-11 Chiron Srl Analysis of samples
EP2428225A3 (de) * 2006-09-10 2012-05-09 Glycotope GmbH Verwendung von menschlichen Zellen von Myeloischer Leukämie zur Expression von Antikörpern
CN101264096B (zh) * 2007-03-12 2011-11-09 中国医学科学院药物研究所 人参皂苷Rg1在制备生精产品中的应用
BRPI0815324A2 (pt) 2007-08-20 2015-07-14 Protalix Ltd "conjugado protêico que contém sacarídeos, processo de separação do conjugado protêico que contém sacarídeos, composição farmacêutica do conjugado protêico que contém sacarídeos, uso do conjugado protêico que contém sacarídeos e composto do conjugado protêico que contém sacarídeos"
TWI488640B (zh) * 2008-04-16 2015-06-21 菲瑞茵國際中心股份有限公司 藥學製劑
JP2012524628A (ja) * 2009-04-22 2012-10-18 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 精巣の機能及び疾患の診断のためのｉｎｖｉｖｏでの１Ｈ磁気共鳴分光法
TWI532495B (zh) 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
US9194011B2 (en) 2009-11-17 2015-11-24 Protalix Ltd. Stabilized alpha-galactosidase and uses thereof
WO2012016576A1 (en) * 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
CN102464713A (zh) * 2010-12-21 2012-05-23 上海丽珠制药有限公司 一种卵泡刺激素的制备方法
BR112013018516B1 (pt) 2011-01-20 2023-11-07 Protalix Ltd Construto de expressão de ácido nucleico, método de produção de uma proteína alfa-galactosidase humana recombinante, proteína alfagalactosidase humana, composição farmacêutica, e, uso de uma proteína alfagalactosidase humana ou de uma composição
CN103619358B (zh) 2011-03-31 2017-02-15 辉凌公司 药物制剂
WO2012168680A1 (en) * 2011-06-06 2012-12-13 Ferring B.V. Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
SG11201608132UA (en) 2014-04-18 2016-11-29 Glycotope Gmbh Controlled ovarian hyperstimulation with improved recombinant human follicle-stimulating hormone
HUE067382T2 (hu) 2018-05-18 2024-10-28 Daiichi Sankyo Co Ltd Anti-MUC1-exatecan antitest-hatóanyag konjugátum

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1057895B (it) * 1975-02-17 1982-03-30 Serono Lab Gonadotropina corionica umana parzialmente desalinizzata per indurre l'ouvulazione
IT1206302B (it) * 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
US6225449B1 (en) * 1991-10-04 2001-05-01 Washington University Hormone analogs with multiple CTP extensions
US5338835A (en) * 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
US5087615A (en) * 1989-03-17 1992-02-11 Applied Research Systems Ars Holding N.V. Novel method of ovulation induction in humans
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
US5834251A (en) * 1994-12-30 1998-11-10 Alko Group Ltd. Methods of modifying carbohydrate moieties
ES2218806T3 (es) * 1997-01-16 2004-11-16 Neose Technologies, Inc. Sialilacion practica in vitro de glicoproteinas recombinantes.
IL141063A (en) * 1998-08-07 2005-06-19 Applied Research Systems Derivatives of pyrrolidine-2-carboxylic acid and piperidine-2-carboxylic acids and pharmaceutical compositions comprising said derivatives for treating infertility
WO2000024755A1 (en) * 1998-10-28 2000-05-04 Baylor College Of Medicine Ovary-specific genes and proteins
DE60032349T2 (de) * 1999-04-26 2007-07-12 Genentech, Inc., South San Francisco Zellenzuchtverfahren für glycoproteine
JP2001299362A (ja) * 1999-12-17 2001-10-30 Takeda Chem Ind Ltd 新規ポリペプチドおよびそのｄｎａ
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones

Also Published As

Publication number Publication date
HRP20040278B1 (hr) 2008-03-31
US20050085412A1 (en) 2005-04-21
ES2261740T3 (es) 2006-11-16
WO2003035686A3 (en) 2003-10-09
CA2464368A1 (en) 2003-05-01
EP1438336A2 (de) 2004-07-21
NO327966B1 (no) 2009-11-02
AU2002340562B2 (en) 2008-10-23
CN1608078B (zh) 2012-07-25
NO20042061L (no) 2004-07-13
UA87433C2 (ru) 2009-07-27
MEP38608A (en) 2011-02-10
EA200400574A1 (ru) 2004-08-26
HRP20040278A2 (en) 2005-04-30
KR20040045885A (ko) 2004-06-02
DK1438336T3 (da) 2006-10-02
JP2005515974A (ja) 2005-06-02
IL161235A0 (en) 2004-09-27
DE60212425T2 (de) 2006-11-09
EP1621549A3 (de) 2006-03-01
EP1621549A2 (de) 2006-02-01
AR036926A1 (es) 2004-10-13
CN1608078A (zh) 2005-04-20
EA007030B1 (ru) 2006-06-30
PT1438336E (pt) 2006-08-31
MXPA04003352A (es) 2004-07-08
IL161235A (en) 2009-07-20
DE60212425D1 (de) 2006-07-27
PL369606A1 (en) 2005-05-02
ZA200402279B (en) 2005-10-26
RS32804A (sr) 2007-02-05
WO2003035686A2 (en) 2003-05-01
EP1438336B1 (de) 2006-06-14
KR100929971B1 (ko) 2009-12-04

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