EA200400574A1 - Гонадотропины для фолликулогенеза - Google Patents

Гонадотропины для фолликулогенеза

Info

Publication number
EA200400574A1
EA200400574A1 EA200400574A EA200400574A EA200400574A1 EA 200400574 A1 EA200400574 A1 EA 200400574A1 EA 200400574 A EA200400574 A EA 200400574A EA 200400574 A EA200400574 A EA 200400574A EA 200400574 A1 EA200400574 A1 EA 200400574A1
Authority
EA
Eurasian Patent Office
Prior art keywords
folliculogenesis
gonadotropins
sialylation
published
high degree
Prior art date
Application number
EA200400574A
Other languages
English (en)
Other versions
EA007030B1 (ru
Inventor
Эрнест Луме
Карло Эмануэле Джартозио
Original Assignee
Апплайд Резеч Системз Арс Холдинг Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23323355&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200400574(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Апплайд Резеч Системз Арс Холдинг Н.В. filed Critical Апплайд Резеч Системз Арс Холдинг Н.В.
Publication of EA200400574A1 publication Critical patent/EA200400574A1/ru
Publication of EA007030B1 publication Critical patent/EA007030B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Abstract

Настоящее изобретение относится к препарату ФСГ, характеризующемуся высокой степенью сиалилирования и демонстрирующему повышенную эффективность.Отчет о международном поиске был опубликован 2003.10.09.
EA200400574A 2001-10-22 2002-10-15 Гонадотропины для фолликулогенеза EA007030B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33808801P 2001-10-22 2001-10-22
PCT/EP2002/011501 WO2003035686A2 (en) 2001-10-22 2002-10-15 Compositions of fsh with high sialylation degree and their use for the preparation of medicaments

Publications (2)

Publication Number Publication Date
EA200400574A1 true EA200400574A1 (ru) 2004-08-26
EA007030B1 EA007030B1 (ru) 2006-06-30

Family

ID=23323355

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400574A EA007030B1 (ru) 2001-10-22 2002-10-15 Гонадотропины для фолликулогенеза

Country Status (24)

Country Link
US (1) US20050085412A1 (ru)
EP (2) EP1438336B1 (ru)
JP (1) JP2005515974A (ru)
KR (1) KR100929971B1 (ru)
CN (1) CN1608078B (ru)
AR (1) AR036926A1 (ru)
AT (1) ATE329930T1 (ru)
AU (1) AU2002340562B2 (ru)
CA (1) CA2464368A1 (ru)
DE (1) DE60212425T2 (ru)
DK (1) DK1438336T3 (ru)
EA (1) EA007030B1 (ru)
ES (1) ES2261740T3 (ru)
HR (1) HRP20040278B1 (ru)
IL (2) IL161235A0 (ru)
ME (1) MEP38608A (ru)
MX (1) MXPA04003352A (ru)
NO (1) NO327966B1 (ru)
PL (1) PL369606A1 (ru)
PT (1) PT1438336E (ru)
RS (1) RS32804A (ru)
UA (1) UA87433C2 (ru)
WO (1) WO2003035686A2 (ru)
ZA (1) ZA200402279B (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0524782D0 (en) * 2005-12-05 2006-01-11 Chiron Srl Analysis of samples
ES2620261T3 (es) * 2006-09-10 2017-06-28 Glycotope Gmbh Uso de células humanas de origen leucémico mieloide para expresión de anticuerpos
CN101264096B (zh) * 2007-03-12 2011-11-09 中国医学科学院药物研究所 人参皂苷Rg1在制备生精产品中的应用
US8742079B2 (en) 2007-08-20 2014-06-03 Protalix Ltd. Saccharide-containing protein conjugates and uses thereof
TWI488640B (zh) * 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
AU2010238758A1 (en) * 2009-04-22 2011-12-15 The Regents Of The University Of California In vivo 1H magnetic resonance spectroscopy for the diagnosis of testicular function and disease
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
US9194011B2 (en) 2009-11-17 2015-11-24 Protalix Ltd. Stabilized alpha-galactosidase and uses thereof
WO2012016576A1 (en) * 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
CN102464713A (zh) * 2010-12-21 2012-05-23 上海丽珠制药有限公司 一种卵泡刺激素的制备方法
DK2665814T3 (en) 2011-01-20 2017-09-11 Protalix Ltd NUCLEIC ACID CONSTRUCTION FOR EXPRESSION OF ALPHA-GALACTOSIDASE IN PLANTS AND PLANT CELLS
JP6087338B2 (ja) 2011-03-31 2017-03-01 フェリング ベスローテン フェンノートシャップ 医薬製剤
EP2717904A1 (en) * 2011-06-06 2014-04-16 Ferring BV Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
JP2017513853A (ja) 2014-04-18 2017-06-01 グリコトープ ゲーエムベーハー 改良された組換えヒト卵胞刺激ホルモンを用いた制御された卵巣過剰刺激
DK3794042T3 (da) 2018-05-18 2024-04-15 Daiichi Sankyo Co Ltd Anti-muc1-exatecet-antistof-lægemiddelkonjugat

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1057895B (it) * 1975-02-17 1982-03-30 Serono Lab Gonadotropina corionica umana parzialmente desalinizzata per indurre l'ouvulazione
IT1206302B (it) * 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
US6225449B1 (en) * 1991-10-04 2001-05-01 Washington University Hormone analogs with multiple CTP extensions
US5338835A (en) * 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
US5087615A (en) * 1989-03-17 1992-02-11 Applied Research Systems Ars Holding N.V. Novel method of ovulation induction in humans
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
US5834251A (en) * 1994-12-30 1998-11-10 Alko Group Ltd. Methods of modifying carbohydrate moieties
IL130964A0 (en) * 1997-01-16 2001-01-28 Cytel Corp Practical in vitro sialylation of recombinant glycoproteins
JP4511042B2 (ja) * 1998-08-07 2010-07-28 メルク セローノ ソシエテ アノニム 不妊症の治療のためのｆｓｈ模倣物
CA2348430A1 (en) * 1998-10-28 2000-05-04 Baylor College Of Medicine Ovary-specific genes and proteins
EP1171615B1 (en) * 1999-04-26 2006-12-13 Genentech, Inc. Cell culture process for glycoproteins
JP2001299362A (ja) * 1999-12-17 2001-10-30 Takeda Chem Ind Ltd 新規ポリペプチドおよびそのｄｎａ
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones

Also Published As

Publication number Publication date
CN1608078A (zh) 2005-04-20
CA2464368A1 (en) 2003-05-01
EP1621549A2 (en) 2006-02-01
UA87433C2 (ru) 2009-07-27
PL369606A1 (en) 2005-05-02
DK1438336T3 (da) 2006-10-02
IL161235A (en) 2009-07-20
HRP20040278B1 (en) 2008-03-31
EP1438336A2 (en) 2004-07-21
ATE329930T1 (de) 2006-07-15
EA007030B1 (ru) 2006-06-30
CN1608078B (zh) 2012-07-25
HRP20040278A2 (en) 2005-04-30
RS32804A (en) 2007-02-05
KR100929971B1 (ko) 2009-12-04
MXPA04003352A (es) 2004-07-08
PT1438336E (pt) 2006-08-31
ES2261740T3 (es) 2006-11-16
NO327966B1 (no) 2009-11-02
WO2003035686A3 (en) 2003-10-09
US20050085412A1 (en) 2005-04-21
JP2005515974A (ja) 2005-06-02
AR036926A1 (es) 2004-10-13
KR20040045885A (ko) 2004-06-02
IL161235A0 (en) 2004-09-27
DE60212425D1 (de) 2006-07-27
WO2003035686A2 (en) 2003-05-01
EP1438336B1 (en) 2006-06-14
AU2002340562B2 (en) 2008-10-23
ZA200402279B (en) 2005-10-26
EP1621549A3 (en) 2006-03-01
DE60212425T2 (de) 2006-11-09
NO20042061L (no) 2004-07-13
MEP38608A (en) 2011-02-10

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Legal Events

Date Code Title Description
PC4A Registration of transfer of a eurasian patent by assignment
PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU