DE60212425D1 - Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln - Google Patents
Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimittelnInfo
- Publication number
- DE60212425D1 DE60212425D1 DE60212425T DE60212425T DE60212425D1 DE 60212425 D1 DE60212425 D1 DE 60212425D1 DE 60212425 T DE60212425 T DE 60212425T DE 60212425 T DE60212425 T DE 60212425T DE 60212425 D1 DE60212425 D1 DE 60212425D1
- Authority
- DE
- Germany
- Prior art keywords
- medicaments
- preparation
- high sialylation
- sialylation rate
- fsh compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33808801P | 2001-10-22 | 2001-10-22 | |
US338088P | 2001-10-22 | ||
PCT/EP2002/011501 WO2003035686A2 (en) | 2001-10-22 | 2002-10-15 | Compositions of fsh with high sialylation degree and their use for the preparation of medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60212425D1 true DE60212425D1 (de) | 2006-07-27 |
DE60212425T2 DE60212425T2 (de) | 2006-11-09 |
Family
ID=23323355
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60212425T Revoked DE60212425T2 (de) | 2001-10-22 | 2002-10-15 | Fsh-zusammensetzungen mit hohem sialylierungsgrad und deren verwendung zur herstellung von arzneimitteln |
Country Status (24)
Country | Link |
---|---|
US (1) | US20050085412A1 (de) |
EP (2) | EP1438336B1 (de) |
JP (1) | JP2005515974A (de) |
KR (1) | KR100929971B1 (de) |
CN (1) | CN1608078B (de) |
AR (1) | AR036926A1 (de) |
AT (1) | ATE329930T1 (de) |
AU (1) | AU2002340562B2 (de) |
CA (1) | CA2464368A1 (de) |
DE (1) | DE60212425T2 (de) |
DK (1) | DK1438336T3 (de) |
EA (1) | EA007030B1 (de) |
ES (1) | ES2261740T3 (de) |
HR (1) | HRP20040278B1 (de) |
IL (2) | IL161235A0 (de) |
ME (1) | MEP38608A (de) |
MX (1) | MXPA04003352A (de) |
NO (1) | NO327966B1 (de) |
PL (1) | PL369606A1 (de) |
PT (1) | PT1438336E (de) |
RS (1) | RS32804A (de) |
UA (1) | UA87433C2 (de) |
WO (1) | WO2003035686A2 (de) |
ZA (1) | ZA200402279B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0524782D0 (en) * | 2005-12-05 | 2006-01-11 | Chiron Srl | Analysis of samples |
ES2620261T3 (es) * | 2006-09-10 | 2017-06-28 | Glycotope Gmbh | Uso de células humanas de origen leucémico mieloide para expresión de anticuerpos |
CN101264096B (zh) * | 2007-03-12 | 2011-11-09 | 中国医学科学院药物研究所 | 人参皂苷Rg1在制备生精产品中的应用 |
US8742079B2 (en) | 2007-08-20 | 2014-06-03 | Protalix Ltd. | Saccharide-containing protein conjugates and uses thereof |
TWI488640B (zh) * | 2008-04-16 | 2015-06-21 | Ferring Int Ct Sa | 藥學製劑 |
AU2010238758A1 (en) * | 2009-04-22 | 2011-12-15 | The Regents Of The University Of California | In vivo 1H magnetic resonance spectroscopy for the diagnosis of testicular function and disease |
TWI532495B (zh) * | 2009-10-05 | 2016-05-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
US9194011B2 (en) | 2009-11-17 | 2015-11-24 | Protalix Ltd. | Stabilized alpha-galactosidase and uses thereof |
WO2012016576A1 (en) * | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
CN102464713A (zh) * | 2010-12-21 | 2012-05-23 | 上海丽珠制药有限公司 | 一种卵泡刺激素的制备方法 |
DK2665814T3 (en) | 2011-01-20 | 2017-09-11 | Protalix Ltd | NUCLEIC ACID CONSTRUCTION FOR EXPRESSION OF ALPHA-GALACTOSIDASE IN PLANTS AND PLANT CELLS |
JP6087338B2 (ja) | 2011-03-31 | 2017-03-01 | フェリング ベスローテン フェンノートシャップ | 医薬製剤 |
EP2717904A1 (de) * | 2011-06-06 | 2014-04-16 | Ferring BV | Pharmazeutische zubereitung mit rekombinantem fsh |
JO3092B1 (ar) | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
JP2017513853A (ja) | 2014-04-18 | 2017-06-01 | グリコトープ ゲーエムベーハー | 改良された組換えヒト卵胞刺激ホルモンを用いた制御された卵巣過剰刺激 |
DK3794042T3 (da) | 2018-05-18 | 2024-04-15 | Daiichi Sankyo Co Ltd | Anti-muc1-exatecet-antistof-lægemiddelkonjugat |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1057895B (it) * | 1975-02-17 | 1982-03-30 | Serono Lab | Gonadotropina corionica umana parzialmente desalinizzata per indurre l'ouvulazione |
IT1206302B (it) * | 1987-06-26 | 1989-04-14 | Serono Cesare Ist Ricerca | Ormone follicolo-stimolante urinario |
US6225449B1 (en) * | 1991-10-04 | 2001-05-01 | Washington University | Hormone analogs with multiple CTP extensions |
US5338835A (en) * | 1989-02-21 | 1994-08-16 | Washington University | CTP-extended form of FSH |
US5087615A (en) * | 1989-03-17 | 1992-02-11 | Applied Research Systems Ars Holding N.V. | Novel method of ovulation induction in humans |
US5541083A (en) * | 1989-10-24 | 1996-07-30 | The Regents Of The University Of California | Method for producing secretable glycosyltransferases and other golgi processing enzymes |
US5834251A (en) * | 1994-12-30 | 1998-11-10 | Alko Group Ltd. | Methods of modifying carbohydrate moieties |
IL130964A0 (en) * | 1997-01-16 | 2001-01-28 | Cytel Corp | Practical in vitro sialylation of recombinant glycoproteins |
JP4511042B2 (ja) * | 1998-08-07 | 2010-07-28 | メルク セローノ ソシエテ アノニム | 不妊症の治療のためのfsh模倣物 |
CA2348430A1 (en) * | 1998-10-28 | 2000-05-04 | Baylor College Of Medicine | Ovary-specific genes and proteins |
EP1171615B1 (de) * | 1999-04-26 | 2006-12-13 | Genentech, Inc. | Zellenzuchtverfahren für glycoproteine |
JP2001299362A (ja) * | 1999-12-17 | 2001-10-30 | Takeda Chem Ind Ltd | 新規ポリペプチドおよびそのdna |
WO2001058493A1 (en) * | 2000-02-11 | 2001-08-16 | Maxygen Aps | Conjugates of follicle stimulating hormones |
-
2002
- 2002-10-15 IL IL16123502A patent/IL161235A0/xx unknown
- 2002-10-15 DK DK02774712T patent/DK1438336T3/da active
- 2002-10-15 ME MEP-386/08A patent/MEP38608A/xx unknown
- 2002-10-15 UA UA20040402998A patent/UA87433C2/ru unknown
- 2002-10-15 KR KR1020047005861A patent/KR100929971B1/ko not_active IP Right Cessation
- 2002-10-15 EA EA200400574A patent/EA007030B1/ru not_active IP Right Cessation
- 2002-10-15 PT PT02774712T patent/PT1438336E/pt unknown
- 2002-10-15 MX MXPA04003352A patent/MXPA04003352A/es active IP Right Grant
- 2002-10-15 EP EP02774712A patent/EP1438336B1/de not_active Revoked
- 2002-10-15 CN CN028260090A patent/CN1608078B/zh not_active Expired - Fee Related
- 2002-10-15 PL PL02369606A patent/PL369606A1/xx not_active Application Discontinuation
- 2002-10-15 EP EP05107252A patent/EP1621549A3/de not_active Withdrawn
- 2002-10-15 CA CA002464368A patent/CA2464368A1/en not_active Abandoned
- 2002-10-15 DE DE60212425T patent/DE60212425T2/de not_active Revoked
- 2002-10-15 WO PCT/EP2002/011501 patent/WO2003035686A2/en active IP Right Grant
- 2002-10-15 US US10/493,638 patent/US20050085412A1/en not_active Abandoned
- 2002-10-15 AU AU2002340562A patent/AU2002340562B2/en not_active Ceased
- 2002-10-15 AT AT02774712T patent/ATE329930T1/de not_active IP Right Cessation
- 2002-10-15 RS YUP-328/04A patent/RS32804A/sr unknown
- 2002-10-15 ES ES02774712T patent/ES2261740T3/es not_active Expired - Lifetime
- 2002-10-15 JP JP2003538199A patent/JP2005515974A/ja active Pending
- 2002-10-22 AR ARP020103989A patent/AR036926A1/es unknown
-
2004
- 2004-03-19 HR HR20040278A patent/HRP20040278B1/xx not_active IP Right Cessation
- 2004-03-23 ZA ZA2004/02279A patent/ZA200402279B/en unknown
- 2004-04-01 IL IL161235A patent/IL161235A/en unknown
- 2004-05-18 NO NO20042061A patent/NO327966B1/no not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: LABORATOIRES SERONO S.A., COINSINS, VAUD, CH |
|
8331 | Complete revocation |