ATE323531T1 - Verwendung von nk-1-rezeptorantagonisten gegen benigne prostatahyperplasie - Google Patents
Verwendung von nk-1-rezeptorantagonisten gegen benigne prostatahyperplasieInfo
- Publication number
- ATE323531T1 ATE323531T1 AT02719751T AT02719751T ATE323531T1 AT E323531 T1 ATE323531 T1 AT E323531T1 AT 02719751 T AT02719751 T AT 02719751T AT 02719751 T AT02719751 T AT 02719751T AT E323531 T1 ATE323531 T1 AT E323531T1
- Authority
- AT
- Austria
- Prior art keywords
- benigne
- receptor antagonists
- prostate hyperplasia
- antagonists against
- hyperplasia
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01109853 | 2001-04-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE323531T1 true ATE323531T1 (de) | 2006-05-15 |
Family
ID=8177209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02719751T ATE323531T1 (de) | 2001-04-23 | 2002-02-02 | Verwendung von nk-1-rezeptorantagonisten gegen benigne prostatahyperplasie |
Country Status (17)
Country | Link |
---|---|
US (1) | US20030004157A1 (de) |
EP (1) | EP1385577B1 (de) |
JP (1) | JP4146730B2 (de) |
KR (1) | KR100599134B1 (de) |
CN (1) | CN100398106C (de) |
AR (1) | AR035935A1 (de) |
AT (1) | ATE323531T1 (de) |
AU (1) | AU2002250876B2 (de) |
BR (1) | BR0209151A (de) |
CA (1) | CA2444395C (de) |
DE (1) | DE60210760T2 (de) |
DK (1) | DK1385577T3 (de) |
ES (1) | ES2261657T3 (de) |
MX (1) | MXPA03009720A (de) |
PT (1) | PT1385577E (de) |
WO (1) | WO2002085458A2 (de) |
ZA (1) | ZA200308110B (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002089802A2 (en) * | 2001-05-08 | 2002-11-14 | Schering Corporation | Use of neurokinin receptor antagonists to treat androgen-dependent diseases |
US6849624B2 (en) * | 2001-07-31 | 2005-02-01 | Hoffmann-La Roche Inc. | Aromatic and heteroaromatic substituted amides |
AU2004208483B8 (en) * | 2003-01-31 | 2008-04-03 | F. Hoffmann-La Roche Ag | Crystalline modifications of 2-(3,5-bis-trifluoromethyl-phenyl)-N-[6-(1,1-dioxo-1lamda6-thiomorpholin-4-yl)-4-(4-fluoro-2-methyl-phenyl)-pyridin-3-yl]-N-methyl-isobutyramide |
NZ544244A (en) * | 2003-07-03 | 2008-10-31 | Hoffmann La Roche | Dual NK1/NK3 antagonists for treating schizophrenia |
ES2246687B2 (es) * | 2004-02-11 | 2006-11-16 | Miguel Muñoz Saez | Utilizacion de antagonistas no peptidicos de receptores nk1 para la produccion de apoptosis en celulas tumorales. |
CA2572645C (en) | 2004-07-06 | 2011-01-18 | F. Hoffmann-La Roche Ag | Process for preparing carboxamide derivatives used as intermediates in the synthesis of nk-1 receptor antagonists |
US20060030600A1 (en) * | 2004-08-06 | 2006-02-09 | Patrick Schnider | Dual NK1/NK3 receptor antagonists for the treatment of schizophrenia |
EP1855655A2 (de) | 2005-02-25 | 2007-11-21 | F. Hoffmann-Roche AG | Tabletten mit verbesserter dispergierbarkeit der arzneisubstanz |
EP3696174A1 (de) | 2005-11-08 | 2020-08-19 | Vertex Pharmaceuticals Incorporated | Heterocyclische modulatoren von atp-bindenden kassettentransportern |
US7671221B2 (en) | 2005-12-28 | 2010-03-02 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
US7754739B2 (en) | 2007-05-09 | 2010-07-13 | Vertex Pharmaceuticals Incorporated | Modulators of CFTR |
US8093268B2 (en) | 2007-01-24 | 2012-01-10 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5-(5-trifluoromethyl-tetrazol-1-yl-benzyl)-(2S-phenylpiperidin-3S-yl-) |
CN101687842B (zh) | 2007-05-09 | 2013-03-06 | 沃泰克斯药物股份有限公司 | Cftr调节剂 |
LT2639223T (lt) | 2007-12-07 | 2017-06-26 | Vertex Pharmaceuticals Incorporated | Cikloalkilkarboksiamido-piridino benzenkarboksirūgščių gamybos būdas |
CN103626744B (zh) | 2007-12-07 | 2016-05-11 | 沃泰克斯药物股份有限公司 | 3-(6-(1-(2,2-二氟苯并[d][1,3]间二氧杂环戊烯-5-基)环丙烷甲酰氨基)-3-甲基吡啶-2-基)苯甲酸的固体形式 |
ES2647531T3 (es) | 2008-02-28 | 2017-12-22 | Vertex Pharmaceuticals Incorporated | Derivados de heteroarilo como moduladores de CFTR |
GB0808747D0 (en) | 2008-05-14 | 2008-06-18 | Glaxo Wellcome Mfg Pte Ltd | Novel compounds |
CN102439007A (zh) | 2009-03-17 | 2012-05-02 | 第一三共株式会社 | 酰胺衍生物 |
WO2010119347A1 (en) * | 2009-04-14 | 2010-10-21 | Helsinn Healthcare S.A. | Netupitant for use in treating bladder dysfunction |
EP2493299A4 (de) * | 2009-10-29 | 2013-04-17 | Merck Sharp & Dohme | Tertiäre amidorexinrezeptorantagonisten |
WO2011127241A2 (en) | 2010-04-07 | 2011-10-13 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyriodin-2-yl)benzoic acid and administration thereof |
KR20160078997A (ko) | 2013-11-08 | 2016-07-05 | 깃세이 야쿠힌 고교 가부시키가이샤 | 카복시메틸피페리딘 유도체 |
KR102280372B1 (ko) | 2013-11-12 | 2021-07-22 | 버텍스 파마슈티칼스 인코포레이티드 | Cftr 매개된 질환 치료용 약제학적 조성물의 제조 방법 |
TWI649307B (zh) | 2014-05-07 | 2019-02-01 | 日商橘生藥品工業股份有限公司 | Cyclohexylpyridine derivative |
CN107110831B (zh) | 2014-11-18 | 2020-02-21 | 弗特克斯药品有限公司 | 进行高通量试验高效液相色谱的方法 |
MX2020008138A (es) * | 2018-02-02 | 2020-10-19 | Eustralis Pharmaceuticals Ltd Trading As Pressura Neuro | Formulaciones parentales y usos de estas. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6175013B1 (en) * | 1994-06-10 | 2001-01-16 | Eli Lilly And Company | Imidazolinyl tachykinin receptor antagonists |
FR2729951B1 (fr) * | 1995-01-30 | 1997-04-18 | Sanofi Sa | Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant |
ID24309A (id) * | 1997-08-06 | 2000-07-13 | Lilly Co Eli | 2-asilaminopropanamina sebagai antagonis reseptor tachykinin |
WO1999007677A1 (en) * | 1997-08-06 | 1999-02-18 | Eli Lilly And Company | 2-acylaminopropanamines as tachykinin receptor antagonists |
JPH11322748A (ja) * | 1998-03-19 | 1999-11-24 | Takeda Chem Ind Ltd | 複素環化合物、その製造法および用途 |
EP1394150B1 (de) * | 1999-02-24 | 2011-01-19 | F. Hoffmann-La Roche AG | 4-Phenylpyridinderivate und deren Verwendung als NK-1 Rezeptorantagonisten |
AU3735000A (en) * | 1999-05-05 | 2000-11-21 | Warner-Lambert Company | Modulation of substance p by gaba analogs and methods relating thereto |
ATE400556T1 (de) * | 2000-07-14 | 2008-07-15 | Hoffmann La Roche | N-oxide als nk1-rezeptorantagonistenprodrugs von 4-phenylpyridinderivaten |
US6849624B2 (en) * | 2001-07-31 | 2005-02-01 | Hoffmann-La Roche Inc. | Aromatic and heteroaromatic substituted amides |
-
2002
- 2002-02-02 MX MXPA03009720A patent/MXPA03009720A/es active IP Right Grant
- 2002-02-02 JP JP2002583031A patent/JP4146730B2/ja not_active Expired - Lifetime
- 2002-02-02 BR BR0209151-8A patent/BR0209151A/pt not_active Application Discontinuation
- 2002-02-02 AU AU2002250876A patent/AU2002250876B2/en not_active Expired
- 2002-02-02 CN CNB028087305A patent/CN100398106C/zh not_active Expired - Lifetime
- 2002-02-02 WO PCT/EP2002/001085 patent/WO2002085458A2/en active IP Right Grant
- 2002-02-02 DK DK02719751T patent/DK1385577T3/da active
- 2002-02-02 EP EP02719751A patent/EP1385577B1/de not_active Expired - Lifetime
- 2002-02-02 DE DE60210760T patent/DE60210760T2/de not_active Expired - Lifetime
- 2002-02-02 PT PT02719751T patent/PT1385577E/pt unknown
- 2002-02-02 AT AT02719751T patent/ATE323531T1/de active
- 2002-02-02 KR KR1020037013798A patent/KR100599134B1/ko active IP Right Grant
- 2002-02-02 ES ES02719751T patent/ES2261657T3/es not_active Expired - Lifetime
- 2002-02-02 CA CA2444395A patent/CA2444395C/en not_active Expired - Lifetime
- 2002-02-07 AR ARP020100393A patent/AR035935A1/es unknown
- 2002-02-08 US US10/071,570 patent/US20030004157A1/en not_active Abandoned
-
2003
- 2003-10-17 ZA ZA2003/08110A patent/ZA200308110B/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20040007503A (ko) | 2004-01-24 |
EP1385577B1 (de) | 2006-04-19 |
CA2444395A1 (en) | 2002-10-31 |
JP2004529931A (ja) | 2004-09-30 |
PT1385577E (pt) | 2006-08-31 |
CN100398106C (zh) | 2008-07-02 |
BR0209151A (pt) | 2004-07-13 |
WO2002085458A3 (en) | 2003-10-30 |
ZA200308110B (en) | 2005-03-30 |
US20030004157A1 (en) | 2003-01-02 |
DK1385577T3 (da) | 2006-08-21 |
KR100599134B1 (ko) | 2006-07-12 |
AU2002250876B2 (en) | 2005-03-03 |
DE60210760T2 (de) | 2006-11-23 |
MXPA03009720A (es) | 2004-01-29 |
CA2444395C (en) | 2010-12-21 |
DE60210760D1 (de) | 2006-05-24 |
JP4146730B2 (ja) | 2008-09-10 |
CN1503684A (zh) | 2004-06-09 |
WO2002085458A2 (en) | 2002-10-31 |
AR035935A1 (es) | 2004-07-28 |
EP1385577A2 (de) | 2004-02-04 |
ES2261657T3 (es) | 2006-11-16 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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