IS7329A - Flúr setinn sýklóalkanóindól og notkun þeirra semprostaglandín D2 viðtaka mótlyfja - Google Patents

Flúr setinn sýklóalkanóindól og notkun þeirra semprostaglandín D2 viðtaka mótlyfja

Info

Publication number
IS7329A
IS7329A IS7329A IS7329A IS7329A IS 7329 A IS7329 A IS 7329A IS 7329 A IS7329 A IS 7329A IS 7329 A IS7329 A IS 7329A IS 7329 A IS7329 A IS 7329A
Authority
IS
Iceland
Prior art keywords
semprostaglandin
cycloalkanoindole
receptor antagonists
fluorine substituted
fluorine
Prior art date
Application number
IS7329A
Other languages
English (en)
Other versions
IS2633B (is
Inventor
Berthelette Carl
Lachance Nicolas
Li Lianhai
Sturino Claudio
Wang Zhaoyin
Original Assignee
Merck Frosst Canada Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Ltd. filed Critical Merck Frosst Canada Ltd.
Publication of IS7329A publication Critical patent/IS7329A/is
Publication of IS2633B publication Critical patent/IS2633B/is

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A—HUMAN NECESSITIES
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    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A—HUMAN NECESSITIES
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
IS7329A 2002-01-24 2004-06-21 Flúor setin sýklóalkanóindól og notkun þeirra sem prostaglandín D2 viðtakamótlyf IS2633B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35138402P 2002-01-24 2002-01-24
PCT/CA2003/000084 WO2003062200A2 (en) 2002-01-24 2003-01-22 Fluoro substituted cycloalkanoindoles and their use as prostaglandin d2 receptor antagonists

Publications (2)

Publication Number Publication Date
IS7329A true IS7329A (is) 2004-06-21
IS2633B IS2633B (is) 2010-06-15

Family

ID=27613492

Family Applications (2)

Application Number Title Priority Date Filing Date
IS7329A IS2633B (is) 2002-01-24 2004-06-21 Flúor setin sýklóalkanóindól og notkun þeirra sem prostaglandín D2 viðtakamótlyf
IS8887A IS8887A (is) 2002-01-24 2010-03-01 Flúor setin sýklóalkanóindól og notkun þeirra sem prostaglandín D2 viðtakamótlyf

Family Applications After (1)

Application Number Title Priority Date Filing Date
IS8887A IS8887A (is) 2002-01-24 2010-03-01 Flúor setin sýklóalkanóindól og notkun þeirra sem prostaglandín D2 viðtakamótlyf

Country Status (39)

Country Link
US (6) US20030158246A1 (is)
EP (3) EP2045241B1 (is)
JP (2) JP4008885B2 (is)
KR (2) KR20070056166A (is)
CN (3) CN101851191A (is)
AR (1) AR038136A1 (is)
AT (1) ATE414690T1 (is)
AU (1) AU2003202343B2 (is)
BR (1) BR0307050A (is)
CA (1) CA2471952C (is)
CY (3) CY1108841T1 (is)
DE (2) DE122009000022I1 (is)
DK (2) DK2045241T3 (is)
DO (1) DOP2003000566A (is)
EA (1) EA006134B1 (is)
EC (1) ECSP045203A (is)
EG (1) EG24978A (is)
ES (2) ES2316717T3 (is)
FR (1) FR09C0010I2 (is)
GE (1) GEP20074078B (is)
HR (1) HRP20040665B1 (is)
IL (3) IL162825A0 (is)
IS (2) IS2633B (is)
JO (1) JO2481B1 (is)
LU (1) LU91534I2 (is)
MX (1) MXPA04007167A (is)
MY (1) MY137040A (is)
NL (1) NL300377I2 (is)
NO (3) NO327322B1 (is)
NZ (1) NZ533786A (is)
PE (1) PE20030982A1 (is)
PL (1) PL208527B1 (is)
PT (2) PT1470107E (is)
RS (2) RS20100338A (is)
SI (2) SI2045241T1 (is)
TW (1) TWI259080B (is)
UA (1) UA75520C2 (is)
WO (1) WO2003062200A2 (is)
ZA (1) ZA200404999B (is)

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