|
US4808608A
(en)
|
1986-01-23 |
1989-02-28 |
Merck & Co., Inc. |
Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use
|
|
DE3631824A1
(de)
|
1986-02-21 |
1988-03-31 |
Bayer Ag |
Cycloalkano(1.2-b)indol-sulfonamide
|
|
GB8924392D0
(en)
|
1989-10-30 |
1989-12-20 |
Bayer Ag |
Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides
|
|
DE60115411D1
(de)
|
2000-04-12 |
2006-01-05 |
Merck Frosst Canada & Co Kirkl |
Verfahren und zusammensetzungen zur behandlung von allergischen zuständen mit pgd2 rezeptor antagonisten
|
|
US20010047027A1
(en)
|
2000-04-12 |
2001-11-29 |
Marc Labelle |
Prostaglandin D2 receptor antagonists
|
|
EP1395590B1
(en)
|
2001-05-23 |
2006-09-27 |
Merck Frosst Canada & Co. |
Dihydropyrrolo¬1,2-a|indole and tetrahydropyrido¬1,2-a|indole derivatives as prostaglandin d2 receptor antagonists
|
|
CA2468880A1
(en)
|
2001-12-14 |
2003-06-26 |
Zentaris Gmbh |
Tetrahydrocarbazole derivatives as ligands for g-protein coupled receptors (gpcr)
|
|
AR038136A1
(es)
|
2002-01-24 |
2004-12-29 |
Merck Frosst Canada Inc |
Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento
|
|
SE0200356D0
(sv)
|
2002-02-05 |
2002-02-05 |
Astrazeneca Ab |
Novel use
|
|
SE0200411D0
(sv)
|
2002-02-05 |
2002-02-05 |
Astrazeneca Ab |
Novel use
|
|
WO2003097042A1
(en)
|
2002-05-16 |
2003-11-27 |
Shionogi & Co., Ltd. |
Pgd2 receptor antagonist
|
|
US7534897B2
(en)
|
2002-05-16 |
2009-05-19 |
Shionogi & Co., Ltd. |
Indole arylsulfonaimide compounds exhibiting PGD 2 receptor antagonism
|
|
GB2388540A
(en)
|
2002-05-17 |
2003-11-19 |
Bayer Ag |
New use of Ramatroban
|
|
TW200307542A
(en)
|
2002-05-30 |
2003-12-16 |
Astrazeneca Ab |
Novel compounds
|
|
SE0201635D0
(sv)
|
2002-05-30 |
2002-05-30 |
Astrazeneca Ab |
Novel compounds
|
|
SE0202241D0
(sv)
|
2002-07-17 |
2002-07-17 |
Astrazeneca Ab |
Novel Compounds
|
|
ATE479686T1
(de)
|
2002-10-30 |
2010-09-15 |
Merck Frosst Canada Ltd |
Pyridopyrrolizin- und pyridoindolizinderivate
|
|
WO2004078719A1
(ja)
|
2003-03-06 |
2004-09-16 |
Ono Pharmaceutical Co., Ltd. |
インドール誘導体化合物およびその化合物を有効成分とする薬剤
|
|
JP2006528938A
(ja)
|
2003-05-20 |
2006-12-28 |
メルク フロスト カナダ リミテツド |
フルオロ−メタンスルホニル置換シクロアルカノインドール、およびプロスタグランジンd2アンタゴニストとしてのこれらの使用
|
|
SE0301569D0
(sv)
|
2003-05-27 |
2003-05-27 |
Astrazeneca Ab |
Novel compounds
|
|
CN1805959A
(zh)
|
2003-06-12 |
2006-07-19 |
麦克弗罗斯特加拿大有限公司 |
作为dp拮抗剂的环烷吡咯并吡啶
|
|
SE0302232D0
(sv)
|
2003-08-18 |
2003-08-18 |
Astrazeneca Ab |
Novel Compounds
|
|
WO2005033099A2
(en)
|
2003-10-03 |
2005-04-14 |
Glenmark Pharmaceuticals Ltd. |
Novel dipeptidyl peptidase iv inhibitors; processes for their preparation and compositions thereof
|
|
RU2006109108A
(ru)
|
2003-10-14 |
2007-11-20 |
Оксаген Лимитед (GB) |
Соединения, обладающие активностью антагонистов crth2 рецепторов
|
|
WO2005040112A1
(en)
|
2003-10-14 |
2005-05-06 |
Oxagen Limited |
Compounds with pgd2 antagonist activity
|
|
GB2407318A
(en)
|
2003-10-23 |
2005-04-27 |
Oxagen Ltd |
Substituted Indol-3-yl acetic acid derivatives
|
|
GB0324763D0
(en)
|
2003-10-23 |
2003-11-26 |
Oxagen Ltd |
Use of compounds in therapy
|
|
SE0303180D0
(sv)
|
2003-11-26 |
2003-11-26 |
Astrazeneca Ab |
Novel compounds
|
|
US7019022B2
(en)
|
2003-12-15 |
2006-03-28 |
Merck Frosst Canada & Co. |
Substituted tetrahydrocarbazole and cyclopentanoindole derivatives
|
|
NZ548396A
(en)
|
2004-01-31 |
2010-06-25 |
Actimis Pharmaceuticals Inc |
Imidazo[1,2-C]pyrimidinylacetic acid derivatives
|
|
WO2005095397A1
(en)
|
2004-03-11 |
2005-10-13 |
Actelion Pharmaceuticals Ltd |
Tetrahydropyridoindole derivatives
|
|
KR101165863B1
(ko)
|
2004-03-11 |
2012-07-13 |
액테리온 파마슈티칼 리미티드 |
인돌-1-일-아세트산 유도체
|
|
US20050234030A1
(en)
|
2004-04-20 |
2005-10-20 |
Wilmin Bartolini |
Modulators of CRTH2, COX-2 and FAAH
|
|
GB0412914D0
(en)
|
2004-06-10 |
2004-07-14 |
Oxagen Ltd |
Compounds
|
|
MY144903A
(en)
|
2004-06-17 |
2011-11-30 |
Novartis Ag |
Pyrrolopyridine derivatives and their use as crth2 antagonists
|
|
AU2005286717A1
(en)
|
2004-09-21 |
2006-03-30 |
Wyeth |
Benzimidazole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof
|
|
EA200700712A1
(ru)
|
2004-09-21 |
2008-02-28 |
Эсерсис, Инк. |
Производные индолуксусной кислоты, способ получения таких производных (варианты), фармацевтическая композиция, набор на их основе, способ ингибирования связывания эндогенных лигандов и способ лечения заболеваний и расстройств, восприимчивых к ингибированию связывания эндогенных лигандов с рецептором crth-2
|
|
GB0427381D0
(en)
|
2004-12-14 |
2005-01-19 |
Novartis Ag |
Organic compounds
|
|
RU2404163C2
(ru)
|
2004-12-27 |
2010-11-20 |
Актелион Фармасьютиклз Лтд |
Производные 2,3,4,9-тетрагидро-1h-карбазола в качестве антагонистов рецептора crth2
|
|
DOP2006000016A
(es)
|
2005-01-26 |
2006-07-31 |
Aventis Pharma Inc |
2-fenil-indoles como antagonistas del receptor de la prostaglandina d2.
|
|
GB2422830A
(en)
|
2005-02-04 |
2006-08-09 |
Oxagen Ltd |
Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor
|
|
GB2422829A
(en)
|
2005-02-04 |
2006-08-09 |
Oxagen Ltd |
Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor
|
|
GB2422831A
(en)
|
2005-02-04 |
2006-08-09 |
Oxagen Ltd |
Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor
|
|
EP1852420B1
(en)
|
2005-02-25 |
2012-10-17 |
Ono Pharmaceutical Co., Ltd. |
Indole compounds for treating respiratory disorders
|
|
GB0504150D0
(en)
|
2005-03-01 |
2005-04-06 |
Oxagen Ltd |
Microcrystalline material
|
|
GB0505048D0
(en)
|
2005-03-11 |
2005-04-20 |
Oxagen Ltd |
Compounds with PGD antagonist activity
|
|
PT1891075E
(pt)
|
2005-05-24 |
2011-11-10 |
Merck Serono Sa |
Derivados espiro tricíclicos como moduladores do crth2
|
|
GB0512944D0
(en)
|
2005-06-24 |
2005-08-03 |
Argenta Discovery Ltd |
Indolizine compounds
|
|
JP5064219B2
(ja)
|
2005-07-22 |
2012-10-31 |
塩野義製薬株式会社 |
Pgd2受容体アンタゴニスト活性を有するアザインドール酸誘導体
|
|
JP5072594B2
(ja)
|
2005-07-22 |
2012-11-14 |
塩野義製薬株式会社 |
Pgd2受容体アンタゴニスト活性を有するインドール誘導体
|
|
EP1915372B1
(en)
|
2005-08-12 |
2013-11-20 |
Merck Canada Inc. |
Indole derivatives as crth2 receptor antagonists
|
|
WO2007022501A2
(en)
|
2005-08-18 |
2007-02-22 |
Microbia, Inc. |
Useful indole compounds
|
|
EP1932839A4
(en)
|
2005-09-06 |
2014-09-10 |
Shionogi & Co |
INDOLECARBOXYLATE ACID DERIVATIVE HAVING ANTAGONIST EFFECT OF THE PGD2 RECEPTOR
|
|
GB0518783D0
(en)
|
2005-09-14 |
2005-10-26 |
Argenta Discovery Ltd |
Indolizine compounds
|
|
GB0521275D0
(en)
|
2005-10-19 |
2005-11-30 |
Argenta Discovery Ltd |
3-Aminoindole compounds
|
|
GB0525141D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
GB0525144D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
GB0525143D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
GB0525337D0
(en)
|
2005-12-13 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
GB0605743D0
(en)
|
2006-03-22 |
2006-05-03 |
Oxagen Ltd |
Salts with CRTH2 antagonist activity
|
|
CN101454284A
(zh)
|
2006-05-26 |
2009-06-10 |
阿斯利康(瑞典)有限公司 |
联芳基或芳基-杂芳基取代的吲哚类化合物
|
|
GB0611695D0
(en)
|
2006-06-13 |
2006-07-26 |
Novartis Ag |
Organic compounds
|
|
EP2046740B1
(en)
|
2006-07-22 |
2012-05-23 |
Oxagen Limited |
Compounds having crth2 antagonist activity
|
|
WO2008014186A1
(en)
|
2006-07-25 |
2008-01-31 |
Sanofi-Aventis |
2-phenyl-indoles as prostaglandin d2 receptor antagonists
|
|
NZ574705A
(en)
|
2006-08-07 |
2011-12-22 |
Actelion Pharmaceuticals Ltd |
(3-amino-1,2,3,4-tetrahydro-9h-carbazol-9-yl)-acetic acid derivatives
|
|
CA2673356A1
(en)
|
2006-12-21 |
2008-06-26 |
Argenta Discovery Limited |
Crth2 antagonists
|
|
GB0625842D0
(en)
|
2006-12-22 |
2007-02-07 |
Argenta Discovery Ltd |
Indolizine derivatives
|
|
AU2007349641A1
(en)
|
2007-03-21 |
2008-09-25 |
Argenta Oral Therapeutics Limited |
Indolizine acetic acid derivatives as CRTH2 antagonists
|
|
GB0719521D0
(en)
|
2007-10-05 |
2007-11-14 |
Argenta Discovery Ltd |
Compounds
|
|
GB0719485D0
(en)
|
2007-10-05 |
2007-11-14 |
Argenta Discovery Ltd |
Compounds
|
|
CN101896178B
(zh)
|
2007-10-10 |
2013-11-20 |
北京赛林泰医药技术有限公司 |
作为crth2受体拮抗剂的杂环化合物
|
|
WO2009061676A2
(en)
|
2007-11-06 |
2009-05-14 |
Amira Pharmaceuticals, Inc. |
Antagonists of pgd2 receptors
|
|
GB0722203D0
(en)
|
2007-11-13 |
2007-12-19 |
Oxagen Ltd |
Use of CRTH2 antagonist compounds
|
|
GB0722216D0
(en)
|
2007-11-13 |
2007-12-27 |
Oxagen Ltd |
Use of crth2 antagonist compounds
|
|
ATE502920T1
(de)
|
2007-12-14 |
2011-04-15 |
Pulmagen Therapeutics Asthma Ltd |
Indole und ihre therapeutische verwendung
|
|
US7750027B2
(en)
|
2008-01-18 |
2010-07-06 |
Oxagen Limited |
Compounds having CRTH2 antagonist activity
|
|
MX2010007833A
(es)
|
2008-01-18 |
2010-08-11 |
Oxagen Ltd |
Compuestos que tienen actividad antagonista de crth2.
|
|
US20110060026A1
(en)
|
2008-01-18 |
2011-03-10 |
George Hynd |
Indoles Active on CRTH2 Receptor
|
|
EP2240444A1
(en)
|
2008-01-22 |
2010-10-20 |
Oxagen Limited |
Compounds having crth2 antagonist activity
|
|
JP2011509990A
(ja)
|
2008-01-22 |
2011-03-31 |
オキサジェン リミテッド |
Crth2アンタゴニスト活性を有する化合物
|
|
JP2011088826A
(ja)
|
2008-01-31 |
2011-05-06 |
Astellas Pharma Inc |
芳香族カルボン酸化合物
|
|
US20110112134A1
(en)
|
2008-05-16 |
2011-05-12 |
Amira Pharmaceuticals, Inc. |
Tricyclic Antagonists of Prostaglandin D2 Receptors
|
|
EP2300425A4
(en)
|
2008-06-24 |
2012-03-21 |
Panmira Pharmaceuticals Llc |
PROSTAGLANDIN D2 RECEPTOR CYCLOALCANEÝBINDLUCK ANTAGONISTS
|
|
JP5394488B2
(ja)
|
2008-07-15 |
2014-01-22 |
エフ.ホフマン−ラ ロシュ アーゲー |
アミノテトラヒドロインダゾロ酢酸
|
|
CA2728311A1
(en)
|
2008-07-15 |
2010-01-21 |
F. Hoffmann-La Roche Ag |
Aminotetrahydroindazoloacetic acids
|
|
EP2346865B1
(en)
|
2008-09-22 |
2015-07-15 |
Merck Canada Inc. |
Indole derivatives as crth2 receptor antagonists
|
|
EP2344497B1
(en)
|
2008-09-22 |
2014-03-05 |
Merck Canada Inc. |
Azaindole derivatives as crth2 receptor antagonists
|
|
AU2009295229B2
(en)
|
2008-09-22 |
2014-02-27 |
Merck Canada Inc. |
Indole derivatives as CRTH2 receptor antagonists
|
|
US20110312945A1
(en)
|
2008-10-01 |
2011-12-22 |
James Jia |
Crth2 modulators
|
|
GB2465062B
(en)
|
2008-11-06 |
2011-04-13 |
Amira Pharmaceuticals Inc |
Cycloalkane(B)azaindole antagonists of prostaglandin D2 receptors
|
|
US20120004233A1
(en)
|
2009-01-26 |
2012-01-05 |
Amira Pharmaceuticals, Inc |
Tricyclic compounds as antagonists of prostaglandin d2 receptors
|
|
BRPI1008906B1
(pt)
|
2009-02-24 |
2019-10-15 |
Merck Sharp & Dohme Corp. |
Composto, composição farmacêutica, e, uso de um composto
|
|
WO2010142934A1
(en)
|
2009-06-12 |
2010-12-16 |
Pulmagen Therapeutics (Asthma) Limited |
Indole derivatives as ligands of crth2 receptors
|
|
US20120115895A1
(en)
|
2009-07-15 |
2012-05-10 |
Merck Serono S.A. |
Tricyclic indole-derived spiro derivatives as crth2 modulators
|
|
WO2011055270A1
(en)
|
2009-11-04 |
2011-05-12 |
Wyeth Llc |
Indole based receptor crth2 antagonists
|
|
SI2558447T1
(sl)
*
|
2010-03-22 |
2015-01-30 |
Actelion Pharmaceuticals Ltd. |
Derivati 3-(heteroaril-amino)-1,2,3,4-tetrahidro-9h-karbazola in njihova uporaba kot modulatorji prostaglandinskega receptorja d2
|
|
US20110311483A1
(en)
|
2010-03-30 |
2011-12-22 |
Ironwood Pharmaceuticals, Inc. |
Crth2 modulators
|
|
WO2012009134A1
(en)
|
2010-07-12 |
2012-01-19 |
Ironwood Pharmaceuticals, Inc. |
Crth2 modulators
|
|
WO2012009137A1
(en)
|
2010-07-12 |
2012-01-19 |
Ironwood Pharmaceuticals, Inc. |
Crth2 modulators
|
|
EP2697223B1
(en)
|
2011-04-14 |
2016-07-13 |
Actelion Pharmaceuticals Ltd. |
7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators
|
|
CN103450218B
(zh)
|
2012-05-29 |
2015-12-23 |
山东亨利医药科技有限责任公司 |
作为crth2受体拮抗剂的吲哚类三并环衍生物
|
|
HRP20181555T1
(hr)
*
|
2014-03-17 |
2018-11-30 |
Idorsia Pharmaceuticals Ltd |
Derivati azaindol-octene kiseline i njihova uporaba kao modulatora receptora prostaglandina d2
|
|
EP3119780B1
(en)
|
2014-03-18 |
2018-08-29 |
Idorsia Pharmaceuticals Ltd |
Azaindole acetic acid derivatives and their use as prostaglandin d2 receptor modulators
|