|
US4808608A
(en)
|
1986-01-23 |
1989-02-28 |
Merck & Co., Inc. |
Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use
|
|
DE3631824A1
(de)
|
1986-02-21 |
1988-03-31 |
Bayer Ag |
Cycloalkano(1.2-b)indol-sulfonamide
|
|
GB8924392D0
(en)
|
1989-10-30 |
1989-12-20 |
Bayer Ag |
Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides
|
|
ATE311200T1
(de)
|
2000-04-12 |
2005-12-15 |
Merck Frosst Canada Inc |
Verfahren und zusammensetzungen zur behandlung von allergischen zuständen mit pgd2 rezeptor antagonisten
|
|
US20010047027A1
(en)
|
2000-04-12 |
2001-11-29 |
Marc Labelle |
Prostaglandin D2 receptor antagonists
|
|
DE60215000T2
(de)
|
2001-05-23 |
2007-08-09 |
Merck Frosst Canada & Co, Kirkland |
Dihydropyrroloil[1,2-a]indol- und Tetrahydropyridol[1,2-a]indol-Derivate als Prostaglandin-D2-Rezeptor-Antagonisten
|
|
JP2005518375A
(ja)
|
2001-12-14 |
2005-06-23 |
ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Gタンパク質結合受容体(gpcr)のためのリガンドとしてのテトラヒドロカルバゾール誘導体
|
|
AR038136A1
(es)
|
2002-01-24 |
2004-12-29 |
Merck Frosst Canada Inc |
Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento
|
|
SE0200411D0
(sv)
|
2002-02-05 |
2002-02-05 |
Astrazeneca Ab |
Novel use
|
|
SE0200356D0
(sv)
|
2002-02-05 |
2002-02-05 |
Astrazeneca Ab |
Novel use
|
|
WO2003097042A1
(en)
|
2002-05-16 |
2003-11-27 |
Shionogi & Co., Ltd. |
Pgd2 receptor antagonist
|
|
EP2423190A1
(en)
|
2002-05-16 |
2012-02-29 |
Shionogi&Co., Ltd. |
Compounds Exhibiting PGD 2 Receptor Antagonism
|
|
GB2388540A
(en)
|
2002-05-17 |
2003-11-19 |
Bayer Ag |
New use of Ramatroban
|
|
TW200307542A
(en)
|
2002-05-30 |
2003-12-16 |
Astrazeneca Ab |
Novel compounds
|
|
SE0201635D0
(sv)
|
2002-05-30 |
2002-05-30 |
Astrazeneca Ab |
Novel compounds
|
|
SE0202241D0
(sv)
|
2002-07-17 |
2002-07-17 |
Astrazeneca Ab |
Novel Compounds
|
|
EP1558614B1
(en)
|
2002-10-30 |
2010-09-01 |
Merck Frosst Canada Ltd. |
Pyridopyrrolizine and pyridoindolizine derivatives
|
|
WO2004078719A1
(ja)
|
2003-03-06 |
2004-09-16 |
Ono Pharmaceutical Co., Ltd. |
インドール誘導体化合物およびその化合物を有効成分とする薬剤
|
|
JP2006528938A
(ja)
|
2003-05-20 |
2006-12-28 |
メルク フロスト カナダ リミテツド |
フルオロ−メタンスルホニル置換シクロアルカノインドール、およびプロスタグランジンd2アンタゴニストとしてのこれらの使用
|
|
SE0301569D0
(sv)
|
2003-05-27 |
2003-05-27 |
Astrazeneca Ab |
Novel compounds
|
|
CN1805959A
(zh)
|
2003-06-12 |
2006-07-19 |
麦克弗罗斯特加拿大有限公司 |
作为dp拮抗剂的环烷吡咯并吡啶
|
|
SE0302232D0
(sv)
|
2003-08-18 |
2003-08-18 |
Astrazeneca Ab |
Novel Compounds
|
|
WO2005033099A2
(en)
|
2003-10-03 |
2005-04-14 |
Glenmark Pharmaceuticals Ltd. |
Novel dipeptidyl peptidase iv inhibitors; processes for their preparation and compositions thereof
|
|
JP2007508363A
(ja)
|
2003-10-14 |
2007-04-05 |
オキサジェン リミテッド |
Crth2アンタゴニスト活性を有する化合物
|
|
WO2005040112A1
(en)
|
2003-10-14 |
2005-05-06 |
Oxagen Limited |
Compounds with pgd2 antagonist activity
|
|
GB0324763D0
(en)
|
2003-10-23 |
2003-11-26 |
Oxagen Ltd |
Use of compounds in therapy
|
|
GB2407318A
(en)
|
2003-10-23 |
2005-04-27 |
Oxagen Ltd |
Substituted Indol-3-yl acetic acid derivatives
|
|
SE0303180D0
(sv)
|
2003-11-26 |
2003-11-26 |
Astrazeneca Ab |
Novel compounds
|
|
US7019022B2
(en)
|
2003-12-15 |
2006-03-28 |
Merck Frosst Canada & Co. |
Substituted tetrahydrocarbazole and cyclopentanoindole derivatives
|
|
DK1718649T3
(da)
|
2004-01-31 |
2009-08-24 |
Actimis Pharmaceuticals Inc |
Imidazo[1,2-c]pyrimidinyleddikesyrederivater
|
|
JP4051398B2
(ja)
|
2004-03-11 |
2008-02-20 |
アクテリオン ファマシューティカルズ リミテッド |
テトラヒドロピリドインドール誘導体
|
|
RU2376286C2
(ru)
|
2004-03-11 |
2009-12-20 |
Актелион Фармасьютиклз Лтд |
Производные индол-1-илуксусной кислоты
|
|
US20050234030A1
(en)
|
2004-04-20 |
2005-10-20 |
Wilmin Bartolini |
Modulators of CRTH2, COX-2 and FAAH
|
|
GB0412914D0
(en)
|
2004-06-10 |
2004-07-14 |
Oxagen Ltd |
Compounds
|
|
MY144903A
(en)
|
2004-06-17 |
2011-11-30 |
Novartis Ag |
Pyrrolopyridine derivatives and their use as crth2 antagonists
|
|
BRPI0515532A
(pt)
|
2004-09-21 |
2008-07-29 |
Athersys Inc |
composto, composição farmacêutica, métodos de inibir a ligação de ligandos endógenos ao receptor de crth-2 em uma célula, de tratar, melhorar ou prevenir um distúrbio responsivo à inibição da ligação de ligandos endógenos ao receptor de crt-2 e de preparar um composto, e, kit
|
|
KR20070115865A
(ko)
|
2004-09-21 |
2007-12-06 |
아더시스 인코포레이티드 |
Crth2 수용체 길항작용을 나타내는 벤즈이미다졸아세트산 및 이의 용도
|
|
GB0427381D0
(en)
|
2004-12-14 |
2005-01-19 |
Novartis Ag |
Organic compounds
|
|
KR101329903B1
(ko)
|
2004-12-27 |
2013-11-14 |
액테리온 파마슈티칼 리미티드 |
Crth2 수용체 길항제로서의2,3,4,9-테트라하이드로-1h-카르바졸유도체
|
|
DOP2006000016A
(es)
|
2005-01-26 |
2006-07-31 |
Aventis Pharma Inc |
2-fenil-indoles como antagonistas del receptor de la prostaglandina d2.
|
|
GB2422829A
(en)
|
2005-02-04 |
2006-08-09 |
Oxagen Ltd |
Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor
|
|
GB2422830A
(en)
|
2005-02-04 |
2006-08-09 |
Oxagen Ltd |
Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor
|
|
GB2422831A
(en)
|
2005-02-04 |
2006-08-09 |
Oxagen Ltd |
Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor
|
|
AU2006216170B2
(en)
|
2005-02-25 |
2012-02-09 |
Ono Pharmaceutical Co., Ltd. |
Indole compound and use thereof
|
|
GB0504150D0
(en)
|
2005-03-01 |
2005-04-06 |
Oxagen Ltd |
Microcrystalline material
|
|
GB0505048D0
(en)
|
2005-03-11 |
2005-04-20 |
Oxagen Ltd |
Compounds with PGD antagonist activity
|
|
WO2006125784A1
(en)
|
2005-05-24 |
2006-11-30 |
Laboratoires Serono S.A. |
Tricyclic spiro derivatives as crth2 modulators
|
|
GB0512944D0
(en)
|
2005-06-24 |
2005-08-03 |
Argenta Discovery Ltd |
Indolizine compounds
|
|
EP1911759A4
(en)
|
2005-07-22 |
2010-07-21 |
Shionogi & Co |
AZAINDOL DERIVATIVE ANTAGONISTIC EFFECT ON PGD2 RECEPTOR
|
|
US7956082B2
(en)
|
2005-07-22 |
2011-06-07 |
Shionogi & Co., Ltd |
Indole derivative having PGD2 receptor antagonist activity
|
|
US7696222B2
(en)
|
2005-08-12 |
2010-04-13 |
Merck Frosst Canada Ltd |
Indole derivatives as CRTH2 receptor antagonists
|
|
US20070203209A1
(en)
|
2005-08-18 |
2007-08-30 |
Wilmin Bartolini |
Useful indole compounds
|
|
JP5147401B2
(ja)
|
2005-09-06 |
2013-02-20 |
塩野義製薬株式会社 |
Pgd2受容体アンタゴニスト活性を有するインドールカルボン酸誘導体
|
|
GB0518783D0
(en)
|
2005-09-14 |
2005-10-26 |
Argenta Discovery Ltd |
Indolizine compounds
|
|
GB0521275D0
(en)
|
2005-10-19 |
2005-11-30 |
Argenta Discovery Ltd |
3-Aminoindole compounds
|
|
GB0525144D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
GB0525143D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
GB0525141D0
(en)
|
2005-12-09 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
GB0525337D0
(en)
|
2005-12-13 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
GB0605743D0
(en)
|
2006-03-22 |
2006-05-03 |
Oxagen Ltd |
Salts with CRTH2 antagonist activity
|
|
US7741360B2
(en)
|
2006-05-26 |
2010-06-22 |
Astrazeneca Ab |
Bi-aryl or aryl-heteroaryl substituted indoles
|
|
GB0611695D0
(en)
|
2006-06-13 |
2006-07-26 |
Novartis Ag |
Organic compounds
|
|
ES2391671T3
(es)
|
2006-07-22 |
2012-11-28 |
Oxagen Limited |
Compuestos con actividad antagonista de CRTH2
|
|
KR20090039735A
(ko)
|
2006-07-25 |
2009-04-22 |
사노피-아벤티스 |
프로스타글란딘 d2 수용체 길항제로서의 2-페닐-인돌
|
|
EP2316824A1
(en)
|
2006-08-07 |
2011-05-04 |
Actelion Pharmaceuticals Ltd. |
(3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates
|
|
CN101605544A
(zh)
|
2006-12-21 |
2009-12-16 |
阿根塔发明有限公司 |
Crth2拮抗剂
|
|
GB0625842D0
(en)
|
2006-12-22 |
2007-02-07 |
Argenta Discovery Ltd |
Indolizine derivatives
|
|
MX2009010068A
(es)
|
2007-03-21 |
2010-02-24 |
Argenta Oral Therapeutics Ltd |
Derivados de acido indolizin acetico como antagonistas de crth2.
|
|
GB0719485D0
(en)
|
2007-10-05 |
2007-11-14 |
Argenta Discovery Ltd |
Compounds
|
|
GB0719521D0
(en)
|
2007-10-05 |
2007-11-14 |
Argenta Discovery Ltd |
Compounds
|
|
US8772312B2
(en)
|
2007-10-10 |
2014-07-08 |
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. |
Heterocyclic compounds as CRTH2 receptor antagonists
|
|
US20100280049A1
(en)
|
2007-11-06 |
2010-11-04 |
Amira Pharmaceuticals, Inc. |
Antagonists of pgd2 receptors
|
|
GB0722216D0
(en)
|
2007-11-13 |
2007-12-27 |
Oxagen Ltd |
Use of crth2 antagonist compounds
|
|
GB0722203D0
(en)
|
2007-11-13 |
2007-12-19 |
Oxagen Ltd |
Use of CRTH2 antagonist compounds
|
|
JP5327762B2
(ja)
|
2007-12-14 |
2013-10-30 |
プルマジェン セラピューティクス(アズマ)リミテッド |
インドールおよびその治療的使用
|
|
US20110060026A1
(en)
|
2008-01-18 |
2011-03-10 |
George Hynd |
Indoles Active on CRTH2 Receptor
|
|
US7750027B2
(en)
|
2008-01-18 |
2010-07-06 |
Oxagen Limited |
Compounds having CRTH2 antagonist activity
|
|
DK2250161T3
(da)
|
2008-01-18 |
2014-01-27 |
Atopix Therapeutics Ltd |
Forbindelser med CRTH2-antagonistaktivitet
|
|
EP2240444A1
(en)
|
2008-01-22 |
2010-10-20 |
Oxagen Limited |
Compounds having crth2 antagonist activity
|
|
WO2009093026A1
(en)
|
2008-01-22 |
2009-07-30 |
Oxagen Limited |
Compounds having crth2 antagonist activity
|
|
JP2011088826A
(ja)
|
2008-01-31 |
2011-05-06 |
Astellas Pharma Inc |
芳香族カルボン酸化合物
|
|
US20110112134A1
(en)
|
2008-05-16 |
2011-05-12 |
Amira Pharmaceuticals, Inc. |
Tricyclic Antagonists of Prostaglandin D2 Receptors
|
|
EP2300425A4
(en)
|
2008-06-24 |
2012-03-21 |
Panmira Pharmaceuticals Llc |
PROSTAGLANDIN D2 RECEPTOR CYCLOALCANEÝBINDLUCK ANTAGONISTS
|
|
WO2010006944A1
(en)
|
2008-07-15 |
2010-01-21 |
F. Hoffmann-La Roche Ag |
Aminotetrahydroindazoloacetic acids
|
|
CA2728311A1
(en)
|
2008-07-15 |
2010-01-21 |
F. Hoffmann-La Roche Ag |
Aminotetrahydroindazoloacetic acids
|
|
WO2010031183A1
(en)
|
2008-09-22 |
2010-03-25 |
Merck Frosst Canada Ltd. |
Indole derivatives as crth2 receptor antagonists
|
|
AU2009295229B2
(en)
|
2008-09-22 |
2014-02-27 |
Merck Canada Inc. |
Indole derivatives as CRTH2 receptor antagonists
|
|
WO2010031184A1
(en)
|
2008-09-22 |
2010-03-25 |
Merck Frosst Canada Ltd. |
Azaindole derivatives as crth2 receptor antagonists
|
|
WO2010039982A1
(en)
|
2008-10-01 |
2010-04-08 |
Ironwood Pharmaceuticals, Inc. |
Crth2 modulators
|
|
GB2465062B
(en)
*
|
2008-11-06 |
2011-04-13 |
Amira Pharmaceuticals Inc |
Cycloalkane(B)azaindole antagonists of prostaglandin D2 receptors
|
|
US20120004233A1
(en)
|
2009-01-26 |
2012-01-05 |
Amira Pharmaceuticals, Inc |
Tricyclic compounds as antagonists of prostaglandin d2 receptors
|
|
MA33134B1
(fr)
|
2009-02-24 |
2012-03-01 |
Merck Canada Inc |
Derives d'indole en tant qu'antagonistes du recepteur crth2
|
|
WO2010142934A1
(en)
|
2009-06-12 |
2010-12-16 |
Pulmagen Therapeutics (Asthma) Limited |
Indole derivatives as ligands of crth2 receptors
|
|
US20120115895A1
(en)
|
2009-07-15 |
2012-05-10 |
Merck Serono S.A. |
Tricyclic indole-derived spiro derivatives as crth2 modulators
|
|
WO2011055270A1
(en)
|
2009-11-04 |
2011-05-12 |
Wyeth Llc |
Indole based receptor crth2 antagonists
|
|
MX2012010820A
(es)
|
2010-03-22 |
2012-10-10 |
Actelion Pharmaceuticals Ltd |
Derivados de 3-(heteroaril-amino)-1, 2, 3, 4-tetrahidro-9h-carbazo l y sus uso como moduladores del receptor de prostaglandina d2.
|
|
US20110311483A1
(en)
|
2010-03-30 |
2011-12-22 |
Ironwood Pharmaceuticals, Inc. |
Crth2 modulators
|
|
US20130259830A1
(en)
|
2010-07-12 |
2013-10-03 |
Ironwood Pharmaceuticals, Inc. |
Crth2 modulators
|
|
WO2012009137A1
(en)
|
2010-07-12 |
2012-01-19 |
Ironwood Pharmaceuticals, Inc. |
Crth2 modulators
|
|
WO2012140612A1
(en)
|
2011-04-14 |
2012-10-18 |
Actelion Pharmaceuticals Ltd |
7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators
|
|
CN103450218B
(zh)
|
2012-05-29 |
2015-12-23 |
山东亨利医药科技有限责任公司 |
作为crth2受体拮抗剂的吲哚类三并环衍生物
|
|
PH12016501764B1
(en)
*
|
2014-03-17 |
2024-05-17 |
Idorsia Pharmaceuticals Ltd |
Azaindole acetic acid derivatives and their use as prostaglandin d2 receptor modulators
|
|
WO2015140701A1
(en)
|
2014-03-18 |
2015-09-24 |
Actelion Pharmaceuticals Ltd |
Azaindole acetic acid derivatives and their use as prostaglandin d2 receptor modulators
|