GB0722216D0 - Use of crth2 antagonist compounds - Google Patents
Use of crth2 antagonist compoundsInfo
- Publication number
- GB0722216D0 GB0722216D0 GBGB0722216.9A GB0722216A GB0722216D0 GB 0722216 D0 GB0722216 D0 GB 0722216D0 GB 0722216 A GB0722216 A GB 0722216A GB 0722216 D0 GB0722216 D0 GB 0722216D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- antagonist compounds
- crth2 antagonist
- crth2
- compounds
- antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0722216.9A GB0722216D0 (en) | 2007-11-13 | 2007-11-13 | Use of crth2 antagonist compounds |
PCT/GB2008/003843 WO2009063215A2 (en) | 2007-11-13 | 2008-11-13 | Use of crth2 antagonist compounds |
US12/779,638 US20110124683A1 (en) | 2007-11-13 | 2010-05-13 | Use of CRTH2 Antagonist Compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0722216.9A GB0722216D0 (en) | 2007-11-13 | 2007-11-13 | Use of crth2 antagonist compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB0722216D0 true GB0722216D0 (en) | 2007-12-27 |
Family
ID=38896181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB0722216.9A Ceased GB0722216D0 (en) | 2007-11-13 | 2007-11-13 | Use of crth2 antagonist compounds |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB0722216D0 (en) |
WO (1) | WO2009063215A2 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
ES2566739T3 (en) | 2008-02-01 | 2016-04-15 | Brickell Biotech, Inc. | Aminoalkylbiphenyl N, N-disubstituted prostaglandin D2 receptor antagonists |
WO2009102893A2 (en) | 2008-02-14 | 2009-08-20 | Amira Pharmaceuticals, Inc. | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 receptors |
US8426449B2 (en) | 2008-04-02 | 2013-04-23 | Panmira Pharmaceuticals, Llc | Aminoalkylphenyl antagonists of prostaglandin D2 receptors |
EP2300425A4 (en) | 2008-06-24 | 2012-03-21 | Panmira Pharmaceuticals Llc | Cycloalkaneýb¨indole angtagonists of prostaglandin d2 receptors |
KR101325367B1 (en) | 2008-07-03 | 2013-11-11 | 판미라 파마슈티칼스, 엘엘씨 | Antagonists of prostaglandin d2 receptors |
GB2463788B (en) | 2008-09-29 | 2010-12-15 | Amira Pharmaceuticals Inc | Heteroaryl antagonists of prostaglandin D2 receptors |
GB2465062B (en) | 2008-11-06 | 2011-04-13 | Amira Pharmaceuticals Inc | Cycloalkane(B)azaindole antagonists of prostaglandin D2 receptors |
US8383654B2 (en) | 2008-11-17 | 2013-02-26 | Panmira Pharmaceuticals, Llc | Heterocyclic antagonists of prostaglandin D2 receptors |
WO2010142934A1 (en) * | 2009-06-12 | 2010-12-16 | Pulmagen Therapeutics (Asthma) Limited | Indole derivatives as ligands of crth2 receptors |
US8785393B2 (en) | 2009-07-31 | 2014-07-22 | Panmira Pharmaceuticals, Llc | Ophthalmic pharmaceutical compositions of DP2 receptor antagonists |
WO2011017201A2 (en) | 2009-08-05 | 2011-02-10 | Amira Pharmaceuticals, Inc. | Dp2 antagonist and uses thereof |
WO2011085033A2 (en) | 2010-01-06 | 2011-07-14 | Amira Pharmaceuticals, Inc. | Dp2 antagonist and uses thereof |
CN102791689B (en) | 2010-03-22 | 2014-10-29 | 埃科特莱茵药品有限公司 | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin D2 receptor modulators |
EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
US20130052190A1 (en) * | 2011-02-22 | 2013-02-28 | Oxagen Limited | CRTH2 Antagonists for Treatment of Eosinophilic Diseases and Conditions |
GB201103837D0 (en) | 2011-03-07 | 2011-04-20 | Oxagen Ltd | Amorphous (5-Fluoro-2-Methyl-3-Quinolin-2-Ylmethyl-Indol-1-Yl)-acetic acid |
JP5964945B2 (en) | 2011-04-14 | 2016-08-03 | アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd | 7- (Heteroaryl-amino) -6,7,8,9-tetrahydropyrido [1,2-a] indoleacetic acid derivatives and their use as prostaglandin D2 receptor modulators |
EP2526945A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | New CRTH2 Antagonists |
EP2548876A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists |
EP2548863A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists. |
BR112014014558A8 (en) * | 2011-12-16 | 2017-07-04 | Atopix Therapeutics Ltd | pharmaceutical composition, use of a crth2 antagonist and a proton pump inhibitor, and kit for the treatment of eosinophilic esophagitis |
MX368179B (en) | 2014-03-17 | 2019-09-23 | Idorsia Pharmaceuticals Ltd | Azaindole acetic acid derivatives and their use as prostaglandin d2 receptor modulators. |
EP3119780B1 (en) | 2014-03-18 | 2018-08-29 | Idorsia Pharmaceuticals Ltd | Azaindole acetic acid derivatives and their use as prostaglandin d2 receptor modulators |
GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
EA035752B1 (en) | 2015-09-15 | 2020-08-05 | Идорсиа Фармасьютиклз Лтд | CRYSTALLINE FORM OF (S)-2-(8-((5-CHLOROPYRIMIDIN-2-YL)(METHYL)AMINO)-2-FLUORO-6,7,8,9-TETRAHYDRO-5H-PYRIDO[3,2-b]INDOL-5-YL)ACETIC ACID AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME |
WO2017104728A1 (en) * | 2015-12-16 | 2017-06-22 | 国立大学法人東京大学 | Medicine for treating food allergy |
RU2756270C2 (en) * | 2016-07-21 | 2021-09-29 | Чиа Тай Тянцин Фармасьютикал Груп Ко., Лтд. | Indole derivative used as crth2 inhibitor |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0324763D0 (en) * | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
GB0504150D0 (en) * | 2005-03-01 | 2005-04-06 | Oxagen Ltd | Microcrystalline material |
GB0505048D0 (en) * | 2005-03-11 | 2005-04-20 | Oxagen Ltd | Compounds with PGD antagonist activity |
GB0605743D0 (en) * | 2006-03-22 | 2006-05-03 | Oxagen Ltd | Salts with CRTH2 antagonist activity |
JP5270542B2 (en) * | 2006-07-22 | 2013-08-21 | オキサジェン リミテッド | Compound having CRTH2 antagonist activity |
-
2007
- 2007-11-13 GB GBGB0722216.9A patent/GB0722216D0/en not_active Ceased
-
2008
- 2008-11-13 WO PCT/GB2008/003843 patent/WO2009063215A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2009063215A2 (en) | 2009-05-22 |
WO2009063215A3 (en) | 2009-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |