ATE321054T1 - Kristalline beta-lactam intermediate - Google Patents

Kristalline beta-lactam intermediate

Info

Publication number
ATE321054T1
ATE321054T1 AT00943708T AT00943708T ATE321054T1 AT E321054 T1 ATE321054 T1 AT E321054T1 AT 00943708 T AT00943708 T AT 00943708T AT 00943708 T AT00943708 T AT 00943708T AT E321054 T1 ATE321054 T1 AT E321054T1
Authority
AT
Austria
Prior art keywords
ratio
nitrile
ketone
crystalline
cefpodoxime proxetil
Prior art date
Application number
AT00943708T
Other languages
English (en)
Inventor
Julia Greil
Johannes Ludescher
Klaus Totschnig
Siegfried Wolf
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of ATE321054T1 publication Critical patent/ATE321054T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT00943708T 1999-05-05 2000-05-03 Kristalline beta-lactam intermediate ATE321054T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0079999A AT408226B (de) 1999-05-05 1999-05-05 Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
EP00943708A EP1173444B1 (de) 1999-05-05 2000-05-03 Kristalline beta-lactam intermediate

Publications (1)

Publication Number Publication Date
ATE321054T1 true ATE321054T1 (de) 2006-04-15

Family

ID=3500007

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0079999A AT408226B (de) 1999-05-05 1999-05-05 Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
AT00943708T ATE321054T1 (de) 1999-05-05 2000-05-03 Kristalline beta-lactam intermediate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0079999A AT408226B (de) 1999-05-05 1999-05-05 Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2

Country Status (10)

Country Link
US (1) US6949641B2 (de)
EP (1) EP1173444B1 (de)
JP (1) JP5047418B2 (de)
KR (1) KR100698443B1 (de)
CN (2) CN1915998B (de)
AT (2) AT408226B (de)
AU (1) AU5807700A (de)
DE (1) DE60026845T2 (de)
HK (1) HK1044759B (de)
WO (1) WO2000066594A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT413383B (de) * 1998-01-09 2006-02-15 Sandoz Ag Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
EP1373276A4 (de) * 2001-02-27 2005-03-02 Ranbaxy Lab Ltd Verfahren zur herstellung von cefpodoxim-proxetil
KR20040018456A (ko) * 2001-07-13 2004-03-03 가네가후치 가가쿠 고교 가부시키가이샤 환원형 보효소 ｑ10을 수용액 중에서 결정화하는 방법
US20060009639A1 (en) * 2002-11-22 2006-01-12 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefpodoxime proxetil
US7280627B2 (en) * 2002-12-09 2007-10-09 The Johns Hopkins University Constrained data-adaptive signal rejector
ES2291547T3 (es) * 2002-12-20 2008-03-01 Lupin Limited Un procedimiento para la preparacion de cefpodoxima proxetil.
WO2004060896A1 (en) * 2003-01-06 2004-07-22 Lupin Limited A process for the manufacture of cefpodoxime proxetil

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486425A (en) * 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
JPS604189A (ja) * 1983-06-20 1985-01-10 Sankyo Co Ltd β−ラクタム系化合物の製造法
JPS6067483A (ja) * 1983-09-24 1985-04-17 Sankyo Co Ltd チアゾリオメチル置換基を有するセフアロスポリン誘導体
DE3804841A1 (de) * 1988-02-17 1989-08-31 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
JPH0331286A (ja) * 1989-06-27 1991-02-12 Sankyo Co Ltd ホルミル基の脱離法
JP2961927B2 (ja) * 1991-02-12 1999-10-12 富士ゼロックス株式会社 ドラム周辺ユニットの通信エラー防止装置
YU48484B (sh) * 1991-05-24 1998-09-18 Hoechst Aktiengesellschaft Kristalne kiselinske adicione soli diastereomerno čistih 1-(2,2-dimetilpropioniloksi)-etilestara 3-cefem-4-karbonske kiseline
EP0531875B1 (de) * 1991-09-07 2004-03-24 Aventis Pharma Deutschland GmbH Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
JP3031286B2 (ja) * 1997-04-24 2000-04-10 日本電気株式会社 印刷物の検査方法
AT413383B (de) * 1998-01-09 2006-02-15 Sandoz Ag Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
IN191496B (de) * 1999-07-30 2003-12-06 Ranbaxy Lab Ltd
KR100342944B1 (ko) * 1999-11-08 2002-07-02 민경윤 고순도 세프포독심 프록세틸의 제조방법

Also Published As

Publication number Publication date
JP2002543207A (ja) 2002-12-17
CN1915998B (zh) 2012-09-05
WO2000066594A1 (en) 2000-11-09
US6949641B2 (en) 2005-09-27
HK1044759A1 (en) 2002-11-01
EP1173444A1 (de) 2002-01-23
KR100698443B1 (ko) 2007-03-23
AU5807700A (en) 2000-11-17
KR20020033616A (ko) 2002-05-07
CN1349539A (zh) 2002-05-15
JP5047418B2 (ja) 2012-10-10
ATA79999A (de) 2001-02-15
DE60026845D1 (de) 2006-05-11
DE60026845T2 (de) 2006-08-17
HK1044759B (zh) 2007-01-05
US20020065262A1 (en) 2002-05-30
AT408226B (de) 2001-09-25
EP1173444B1 (de) 2006-03-22
CN1915998A (zh) 2007-02-21

Similar Documents

Publication Publication Date Title
PT874853E (pt) Processo de preparacao de cefdinir
IL169534A0 (en) N-(1-benzyl-2-oxo-2-(1-piperazinyl) ethyl)-1-piperidincarboxamid-derivatives and related compounds use as cgrp-antagonists for headache
HUP0002987A2 (hu) Cefdinir diciklohexil-amin sója és eljárás a só előállítására valamint a vegyület sójából történő felszabadítására
HUP0302345A2 (hu) Új triazolo-pirimidin-vegyületek, ezek intermedierjei és eljárás az előállításukra
MY140677A (en) Modified amino acids, pharmaceuticals containing these compounds and method for their production
FI103337B1 (fi) Menetelmä terapeuttisesti käyttökelpoisten substituoitujen 2-okso-1H-atsepiinien valmistamiseksi
AU2003255424A1 (en) A cefdinir intermediate
WO2004031145A3 (en) Lactam-containing diaminoalkyl, beta-aminoacids, alpha-aminoacids and derivatives thereof as factor xa inhibitors
MXPA03011954A (es) Nuevos derivados de acido sulfonico.
DZ3156A1 (fr) Nouvelle forme polymorphe du sel d'acide 5-Ä4-Ä2-(n-methyl-n-(2-pyridyl)amino)ethoxyÜbenzylÜthiazolidine-2,4-dione, maleique.
ATE321054T1 (de) Kristalline beta-lactam intermediate
WO2002080853A3 (en) Fused heterocyclic inhibitors of factor xa
DK0658558T3 (da) Adskillelse af cephalosporinisomere
DE60008508D1 (de) Agglomerate durch kristallisation
CA2124322A1 (en) Process for the purification of a 3-cephem-4-carboxylic acid derivative
AU1122288A (en) Intermediates for the production of halogenated protease inhibitors
RU93042473A (ru) Способ ацилирования 7-аминогруппы цефалоспоранового кольца
EA200600563A1 (ru) Способ получения рензаприда и его промежуточных соединений
CA2326441A1 (en) Process for purification of a cephalosporin derivative
EP0347777A3 (de) Verfahren zur Herstellung von Cephalosporin und Zwischenverbindungen
CA2436863A1 (en) Process and ester derivatives useful for preparation of cephalosporins
EE05136B1 (et) Asendatud imidasopridiinhendite valmistamise meetod
AU5684099A (en) Process for preparing piperazic acid and its conversion to n-acylated bicyclic rings containing n,n-linkages useful as intermediates for caspase inhibitors
HUP0300869A2 (hu) Eljárás klavulánsavsók előállítására
FI66876C (fi) Foerfarande foer framstaellning av antibakteriellt aktiv 7beta(syn-2-metoxi-imino-2-(2-amino-4-tiazolyl)acetamido)-3-(1-(2-sulfaminoetyl)tetrazol-5-yltiometyl)-3-cefem-4-karboxylsyra

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties