ATE319812T1 - Knochen-vorläufer-zellen: zusammensetzungen und methoden - Google Patents
Knochen-vorläufer-zellen: zusammensetzungen und methodenInfo
- Publication number
- ATE319812T1 ATE319812T1 AT95928831T AT95928831T ATE319812T1 AT E319812 T1 ATE319812 T1 AT E319812T1 AT 95928831 T AT95928831 T AT 95928831T AT 95928831 T AT95928831 T AT 95928831T AT E319812 T1 ATE319812 T1 AT E319812T1
- Authority
- AT
- Austria
- Prior art keywords
- precursor cells
- methods
- bone precursor
- bone
- compositions
- Prior art date
Links
- 210000000988 bone and bone Anatomy 0.000 title abstract 6
- 239000002243 precursor Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 210000000963 osteoblast Anatomy 0.000 abstract 2
- 208000004434 Calcinosis Diseases 0.000 abstract 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 abstract 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 230000008468 bone growth Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 210000002744 extracellular matrix Anatomy 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 230000003394 haemopoietic effect Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/289,794 US5972703A (en) | 1994-08-12 | 1994-08-12 | Bone precursor cells: compositions and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE319812T1 true ATE319812T1 (de) | 2006-03-15 |
Family
ID=23113132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95928831T ATE319812T1 (de) | 1994-08-12 | 1995-08-11 | Knochen-vorläufer-zellen: zusammensetzungen und methoden |
Country Status (7)
Country | Link |
---|---|
US (3) | US5972703A (de) |
EP (1) | EP0804551B1 (de) |
AT (1) | ATE319812T1 (de) |
AU (1) | AU712247B2 (de) |
CA (1) | CA2200197A1 (de) |
DE (1) | DE69534847T2 (de) |
WO (1) | WO1996005290A1 (de) |
Families Citing this family (97)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5719058A (en) * | 1995-04-10 | 1998-02-17 | Merck & Co., Inc. | Method for producing a highly enriched population of osteoclast cells |
WO1997026326A1 (en) * | 1996-01-16 | 1997-07-24 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and non-hematopoietic tissues and their use |
ATE295875T1 (de) * | 1996-03-01 | 2005-06-15 | Isotis Nv | Verfahren zur in vitro herstellung von knochen |
US20040224300A1 (en) * | 1997-01-24 | 2004-11-11 | Shuji Terashima | Method for separating nucleated cells |
ATE218896T1 (de) | 1997-07-16 | 2002-06-15 | Isotis Nv | Vorrichtung zur knochenbehandlung bestehend aus abbaubarem thermoplastischen copolyester und kultivierten zellen |
US6576465B1 (en) * | 1997-11-10 | 2003-06-10 | The Regents Of The University Of Michigan | Human bone accessory cells |
WO1999028444A1 (en) | 1997-12-02 | 1999-06-10 | Zen Bio, Inc. | Differentiation of adipose stromal cells into osteoblasts and uses thereof |
US6326507B1 (en) * | 1998-06-19 | 2001-12-04 | Trustees Of Dartmouth College | Therapeutic compounds and methods of use |
IT1302534B1 (it) * | 1998-12-21 | 2000-09-05 | Fidia Advanced Biopolymers Srl | Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per |
DE20023640U1 (de) * | 1999-10-06 | 2005-06-23 | Tigenix N.V. | Isolierung von Vorläuferzellen und deren Verwendung zum Wiederaufbau von Bindegewebe |
DE19956503A1 (de) * | 1999-11-24 | 2001-06-21 | Universitaetsklinikum Freiburg | Spritzbares Knochenersatzmaterial |
DK1234031T3 (en) | 1999-11-30 | 2017-07-03 | Mayo Foundation | B7-H1, AN UNKNOWN IMMUNE REGULATORY MOLECULE |
ES2304359T3 (es) * | 1999-12-28 | 2008-10-16 | The Regents Of The University Of Michigan | Procedimiento de formacion ex vivo de hueso de mamiferos y usos del mismo. |
US6811776B2 (en) | 2000-12-27 | 2004-11-02 | The Regents Of The University Of Michigan | Process for ex vivo formation of mammalian bone and uses thereof |
US20090233270A9 (en) * | 2000-08-02 | 2009-09-17 | St Croix Brad | Secreted and cytoplasmic tumor endothelial markers |
US20030228687A1 (en) * | 2000-08-07 | 2003-12-11 | The Regents Of The University Of Michigan | Human bone accessory cells |
US7435755B2 (en) * | 2000-11-28 | 2008-10-14 | The Trustees Of Dartmouth College | CDDO-compounds and combination therapies thereof |
US20030008328A1 (en) * | 2001-07-03 | 2003-01-09 | Wironen John F. | Quantitative in vitro bone induction assay |
ES2539105T3 (es) * | 2001-07-06 | 2015-06-26 | Asterias Biotherapeutics, Inc. | Células mesenquimatosas y osteoblastos procedentes de células madre embrionarias humanas |
AU2002226426A1 (en) * | 2002-01-09 | 2003-07-24 | Alberto Gorrochategui Barrueta | Composition and method of creating, regenerating and repairing tissues using a cell-carrying biological implant which is enriched with a platelet concentrate and supplements |
US20070141036A1 (en) * | 2002-01-09 | 2007-06-21 | Alberto Gorrochategui Barrueta | Composition and procedure for tissue creation, regeneration and repair by a cell-bearing biological implant enriched with platelet concentrate and supplements |
EP1465615B1 (de) * | 2002-01-15 | 2012-08-01 | Trustees of Dartmouth College | Trizyklische bisenon-derivate und verfahren zu ihrer verwendung |
US7498040B2 (en) | 2005-10-12 | 2009-03-03 | Lifenet Health | Compositions for repair of defects in osseous tissues, and methods of making the same |
US7744597B2 (en) * | 2002-06-26 | 2010-06-29 | Lifenet Health | Device and process for producing fiber products and fiber products produced thereby |
US20040193274A1 (en) * | 2003-03-28 | 2004-09-30 | Trieu Hai H. | Materials and methods for augmenting and/or repairing intervertebral discs |
US7494811B2 (en) | 2003-05-01 | 2009-02-24 | Lifenet Health | In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby |
ES2491891T3 (es) | 2004-01-16 | 2014-09-08 | Carnegie Mellon University | Marcaje celular para técnicas de resonancia magnética nuclear |
US7622108B2 (en) * | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
CA2563518C (en) * | 2004-04-23 | 2014-09-02 | Bioe, Inc. | Multi-lineage progenitor cells |
PL1810026T3 (pl) | 2004-10-06 | 2018-08-31 | Mayo Foundation For Medical Education And Research | B7-H1 i PD-1 w leczeniu raka nerkowokomórkowego |
KR100702250B1 (ko) * | 2005-06-13 | 2007-04-03 | 세원셀론텍(주) | 피브린 혼합형 골절 유합용 반고형성 뼈세포 조성물 및이의 제조방법 |
WO2007038471A2 (en) * | 2005-09-27 | 2007-04-05 | Regenetech, Inc. | Rotatable time varying electromagnetic force bioreactor and method of using the same |
US20090215084A1 (en) * | 2006-01-05 | 2009-08-27 | Mayo Foundation For Medical Education And Research | B7-h1 and b7-h4 in cancer |
WO2007082144A2 (en) * | 2006-01-05 | 2007-07-19 | Mayo Foundation For Medical Education And Research | B7-h1 and survivin in cancer |
US8076136B2 (en) * | 2006-03-30 | 2011-12-13 | The United States Of America As Represented By The United States National Aeronautics And Space Administration | Mineralized three-dimensional bone constructs |
WO2007120911A2 (en) * | 2006-04-14 | 2007-10-25 | Carnegie Mellon University | Cellular labeling and quantification for nuclear magnetic resonance techniques |
WO2008054509A2 (en) * | 2006-04-14 | 2008-05-08 | Celsense, Inc. | Methods for assessing cell labeling |
US7727763B2 (en) * | 2006-04-17 | 2010-06-01 | Bioe, Llc | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
US8298528B2 (en) * | 2006-04-17 | 2012-10-30 | Hepacore Ltd. | Methods for bone regeneration using endothelial progenitor cell preparations |
WO2007124361A2 (en) * | 2006-04-20 | 2007-11-01 | Mayo Foundation For Medical Education And Research | Soluble b7-h1 |
CA2670099A1 (en) * | 2006-11-17 | 2008-05-29 | Trustees Of Dartmouth College | Synthesis and biological activities of new tricyclic-bis-enones (tbes) |
US8921340B2 (en) | 2006-11-17 | 2014-12-30 | Trustees Of Dartmouth College | Methods for using synthetic triterpenoids in the treatment of bone or cartilage diseases or conditions |
WO2008064132A2 (en) * | 2006-11-17 | 2008-05-29 | Trustees Of Dartmouth College | Synthetic triterpenoids and tricyclic-bis-enones for use in stimulating bone and cartilage growth |
EP2170975B1 (de) * | 2007-07-10 | 2018-05-02 | Carnegie Mellon University | Zusammensetzungen und verfahren zur herstellung von zellmarkern für kernresonanztechniken |
EP2192908A4 (de) * | 2007-07-25 | 2010-09-01 | Bioe Inc | Differenzierung von vorläuferzellen mehrerer abstammung gegenüber chondrozyten |
WO2009023845A2 (en) * | 2007-08-15 | 2009-02-19 | The Board Of Regents Of The University Of Texas System | Combination therapy with synthetic triterpenoids and gemcitabine |
WO2009064957A1 (en) * | 2007-11-14 | 2009-05-22 | Osteosphere, Llc | Development of a human colloidal bone graft material |
WO2009064917A2 (en) * | 2007-11-14 | 2009-05-22 | Osteosphere, Llc | Generation of an hla-negative osteogenic precursor cell line |
WO2009064956A1 (en) * | 2007-11-14 | 2009-05-22 | Osteosphere, Llc | A novel tissue culture platform for screening of potential bone remodeling agents |
WO2009064958A1 (en) * | 2007-11-14 | 2009-05-22 | Osteosphere, Llc | Ex-vivo production of human demineralized bone matrix |
KR101618380B1 (ko) * | 2007-12-21 | 2016-05-04 | 본 테라퓨틱스 소시에테아노님 | 염증성 류마티스 질환의 치료에 있어서의 인간 골-형성 세포 |
EA022166B1 (ru) * | 2008-01-11 | 2015-11-30 | Ритэ Фамэсутиклс, Инк. | Синтетические тритерпеноиды и их применение в лечении заболеваний |
US20100278788A1 (en) * | 2008-01-11 | 2010-11-04 | Bone Therapeutics, S.A. | Osteogenic Differentiation Of Bone Marrow Stem Cells And Mesenchymal Stem Cells Using A Combination Of Growth Factors |
US20110020325A1 (en) * | 2008-02-29 | 2011-01-27 | Kwon Eugene D | Methods for reducing granulomatous inflammation |
CA2721665C (en) | 2008-04-18 | 2017-01-24 | Reata Pharmaceuticals, Inc. | Compounds including an anti-inflammatory pharmacore and methods of use |
US7943778B2 (en) | 2008-04-18 | 2011-05-17 | Reata Pharmaceuticals, Inc. | Antioxidant inflammation modulators: C-17 homologated oleanolic acid derivatives |
CN102083442B (zh) | 2008-04-18 | 2014-08-13 | 里亚塔医药公司 | 抗氧化剂炎症调节剂:在c-17具有氨基和其它修饰的齐墩果酸衍生物 |
CN102164941B (zh) | 2008-04-18 | 2015-05-27 | 里亚塔医药公司 | 抗氧化剂炎症调节剂:具有饱和c环的齐墩果酸衍生物 |
TW201004627A (en) | 2008-04-18 | 2010-02-01 | Reata Pharmaceuticals Inc | Antioxidant inflammation modulators: novel derivatives of oleanolic acid |
US20110110863A1 (en) * | 2008-05-02 | 2011-05-12 | Celsense, Inc. | Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications |
KR20110013450A (ko) | 2008-05-07 | 2011-02-09 | 본 테라퓨틱스 소시에테아노님 | 간엽 줄기 세포 및 골-형성 세포 |
BE1018578A5 (fr) * | 2008-05-07 | 2011-04-05 | Bone Therapeutics Sa | Cellules formatrices d'os humains dans le traitement d'etats et de maladies osseuses associes a une immunodeficience ou une immunosuppression. |
US20110182866A1 (en) * | 2008-05-15 | 2011-07-28 | University Of Miami | Isolation of stem cell precursors and expansion in non-adherent conditions |
EP2294187A2 (de) * | 2008-05-21 | 2011-03-16 | BioE LLC | Differenzierung von mehrlinien-vorläuferzellen zu pankreaszellen |
US8314137B2 (en) * | 2008-07-22 | 2012-11-20 | Trustess Of Dartmouth College | Monocyclic cyanoenones and methods of use thereof |
JPWO2010021162A1 (ja) * | 2008-08-19 | 2012-01-26 | 国立大学法人大阪大学 | 骨組織再生用の細胞製剤 |
WO2010077722A1 (en) * | 2008-12-30 | 2010-07-08 | Centocor Ortho Biotech Inc. | Serum markers predicting clinical response to anti-tnf antibodies in patients with ankylosing spondylitis |
ES2598006T3 (es) | 2009-04-24 | 2017-01-24 | Vanderbilt University | Anticuerpos anti-TGF-beta para la inducción del crecimiento óseo |
WO2012048275A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
SG11201401434TA (en) | 2011-10-11 | 2014-09-26 | Bone Therapeutics Sa | Uses of growth and differentiation factor 8 (gdf-8) |
US8921419B2 (en) | 2012-05-08 | 2014-12-30 | Trustees Of Dartmouth College | Triterpenoids and compositions containing the same |
AU2013322604B2 (en) | 2012-09-26 | 2018-01-18 | Bone Therapeutics S.A. | Formulations involving solvent/detergent-treated plasma (S/D plasma) and uses thereof |
CA2902155C (en) | 2013-02-22 | 2023-05-23 | Lifenet Health | Packaging assembly for storing tissue and cellular material |
US9302005B2 (en) | 2013-03-14 | 2016-04-05 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
US10172911B2 (en) | 2013-10-01 | 2019-01-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of modulating erythropoiesis with arginine vasopressin receptor 1B molecules |
US10259875B2 (en) | 2013-10-01 | 2019-04-16 | Mayo Foundation For Medical Education And Research | Methods for treating cancer in patients with elevated levels of BIM |
WO2015073913A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
JP2015097506A (ja) * | 2013-11-19 | 2015-05-28 | 国立大学法人大阪大学 | 細胞表面マーカーをフローサイトメトリーで分析可能な骨芽細胞又は骨芽細胞に分化し得る細胞を得る方法 |
US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
WO2015179654A1 (en) | 2014-05-22 | 2015-11-26 | Mayo Foundation For Medical Education And Research | Distinguishing antagonistic and agonistic anti b7-h1 antibodies |
US10517875B2 (en) | 2014-07-23 | 2019-12-31 | Mayo Foundation for Medical Engineering and Research | Targeting DNA-PKcs and B7-H1 to treat cancer |
WO2016049421A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled feed |
CA2977062A1 (en) * | 2015-02-20 | 2016-08-25 | Idexx Laboratories, Inc. | Homogenous immunoassay with compensation for background signal |
WO2016170112A1 (en) | 2015-04-23 | 2016-10-27 | Bone Therapeutics S.A. | In vitro preservation of therapeutic cells |
WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
WO2017075045A2 (en) | 2015-10-30 | 2017-05-04 | Mayo Foundation For Medical Education And Research | Antibodies to b7-h1 |
US11406721B2 (en) | 2016-02-22 | 2022-08-09 | The Regents Of The University Of California | Compositions and methods for imaging cell populations |
EP3464565A4 (de) | 2016-05-25 | 2020-01-01 | Terumo BCT, Inc. | Zellexpansion |
US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
EP3656842A1 (de) | 2017-03-31 | 2020-05-27 | Terumo BCT, Inc. | Zellexpansion |
US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
AU2018351804B2 (en) | 2017-10-20 | 2020-07-09 | Bone Therapeutics Sa | Methods for differentiating mesenchymal stem cells |
WO2019099615A1 (en) | 2017-11-17 | 2019-05-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of copeptin to modulate the immune response and hematopoiesis, and stimulate bone growth |
KR20210074303A (ko) | 2018-09-25 | 2021-06-21 | 본 테라퓨틱스 소시에테아노님 | 중간엽 줄기 세포의 분화 방법 |
WO2020229526A1 (en) | 2019-05-13 | 2020-11-19 | Bone Therapeutics Sa | Improved lyophilized formulations involving hyaluronic acid and plasmatic proteins, and uses thereof |
JP2024511064A (ja) | 2021-03-23 | 2024-03-12 | テルモ ビーシーティー、インコーポレーテッド | 細胞捕獲及び増殖 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56145222A (en) * | 1980-04-28 | 1981-11-11 | Toshiyuki Hamaoka | Improved antibody and its preparation |
US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
US4714680B1 (en) * | 1984-02-06 | 1995-06-27 | Univ Johns Hopkins | Human stem cells |
US5108753A (en) * | 1988-04-08 | 1992-04-28 | Creative Biomolecules | Osteogenic devices |
US4904259A (en) * | 1988-04-29 | 1990-02-27 | Samuel Itay | Compositions and methods for repair of cartilage and bone |
US5061620A (en) * | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
US5622853A (en) * | 1990-05-01 | 1997-04-22 | Becton Dickinson And Company | T lymphocyte precursor |
US5541072A (en) * | 1994-04-18 | 1996-07-30 | Immunivest Corporation | Method for magnetic separation featuring magnetic particles in a multi-phase system |
US5197985A (en) * | 1990-11-16 | 1993-03-30 | Caplan Arnold I | Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells |
US5226914A (en) * | 1990-11-16 | 1993-07-13 | Caplan Arnold I | Method for treating connective tissue disorders |
US5118667A (en) * | 1991-05-03 | 1992-06-02 | Celtrix Pharmaceuticals, Inc. | Bone growth factors and inhibitors of bone resorption for promoting bone formation |
CA2111845C (en) * | 1991-06-18 | 2001-08-28 | Arnold I. Caplan | Monoclonal antibodies specific for marrow-derived mesenchymal cells |
US5286642A (en) * | 1992-06-24 | 1994-02-15 | The Procter & Gamble Company | Rat osteosarcoma cell line OSR5TR2 |
JPH08503198A (ja) * | 1992-11-03 | 1996-04-09 | クリエイティブ バイオモレキュルズ,インコーポレイテッド | Op−3誘導形態形成 |
-
1994
- 1994-08-12 US US08/289,794 patent/US5972703A/en not_active Expired - Fee Related
-
1995
- 1995-08-11 AU AU32442/95A patent/AU712247B2/en not_active Ceased
- 1995-08-11 EP EP95928831A patent/EP0804551B1/de not_active Expired - Lifetime
- 1995-08-11 US US08/793,053 patent/US6740493B1/en not_active Expired - Fee Related
- 1995-08-11 DE DE69534847T patent/DE69534847T2/de not_active Expired - Fee Related
- 1995-08-11 CA CA002200197A patent/CA2200197A1/en not_active Abandoned
- 1995-08-11 WO PCT/US1995/010293 patent/WO1996005290A1/en active IP Right Grant
- 1995-08-11 AT AT95928831T patent/ATE319812T1/de not_active IP Right Cessation
-
2004
- 2004-05-25 US US10/853,647 patent/US7498170B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69534847D1 (de) | 2006-05-04 |
DE69534847T2 (de) | 2006-11-16 |
EP0804551A1 (de) | 1997-11-05 |
US6740493B1 (en) | 2004-05-25 |
US5972703A (en) | 1999-10-26 |
AU712247B2 (en) | 1999-11-04 |
CA2200197A1 (en) | 1996-02-22 |
US7498170B2 (en) | 2009-03-03 |
EP0804551B1 (de) | 2006-03-08 |
AU3244295A (en) | 1996-03-07 |
US20040214241A1 (en) | 2004-10-28 |
WO1996005290A1 (en) | 1996-02-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE319812T1 (de) | Knochen-vorläufer-zellen: zusammensetzungen und methoden | |
DE69326082D1 (de) | Kalzium phosphat als hydroxyapatit-vorläufer und verfahren zur herstellung und verwendung derselben | |
ATE478135T1 (de) | Differenzierung in osteoblasten der fettgewebe- stromalen zellen und ihre verwendungen | |
MXPA04001334A (es) | Materiales y metodos para promover la reparacion de tejido nervioso. | |
CO5130020A1 (es) | Metodo para incrementar la dureza y tenacidad del hueso proceso para la manufactura de un medicamento que contiene una hormona paratiroide | |
DK0881908T3 (da) | Anvendelse af fiberblastvækstfaktorer til stimulering af knoglevækst | |
NL7601628A (nl) | Biologisch aanvaardbaar keramisch glas en toe- passing van het glas voor het vervaardigen van beenderprotesen, alsmede aldus verkregen protese. | |
MY141384A (en) | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | |
BR0016058A (pt) | Compostos de fosfonato | |
RS49780B (sr) | Primena derivata fumarne kiseline u transplantacionoj medicini | |
DE19581649T1 (de) | Biologisches Material und Knochenimplantat für die Wiederherstellung und den Austausch von Knochen | |
ATE295734T1 (de) | Verwendung von fibroblasten-wachstumsfaktor analogen zur stimulation des knochenwachstums | |
ATE365045T1 (de) | Vermehrung des weich- sowie des knochengewebes anhand von aus muskeln stammenden vorläuferzellen,sowie damit verbundene zusammensetzungen und behandlungsformen | |
BR0317888A (pt) | Cristais do hormÈnio do crescimento humano e processos para preparação dos mesmos | |
DE3690341D2 (en) | Bone cement | |
CN106365630A (zh) | 一种抗压强度和断裂韧性较好的生物陶瓷 | |
TR200200278T2 (tr) | Kalsilitik bileşimler | |
ATE342062T1 (de) | Angiotensin ii zur verbesserung der befruchtung | |
AU2003293870A1 (en) | Composite materials made of calcium compounds and polysaccharides containing glucuronic acid and/or iduronic acid | |
MX9704296A (es) | Lineas celulares de condrocito. | |
Liu | Novel high phosphate low fluoride containing bioactive glasses for hard and soft tissue repair | |
Block | Discussion: Ridge augmentation using solid and porous hydroxylapatite particles with and without autogenous bone or plaster |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0804551 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |