ATE317023T1 - Methode zum nachweis von variationen oder polymorphismen - Google Patents

Methode zum nachweis von variationen oder polymorphismen

Info

Publication number
ATE317023T1
ATE317023T1 AT00971828T AT00971828T ATE317023T1 AT E317023 T1 ATE317023 T1 AT E317023T1 AT 00971828 T AT00971828 T AT 00971828T AT 00971828 T AT00971828 T AT 00971828T AT E317023 T1 ATE317023 T1 AT E317023T1
Authority
AT
Austria
Prior art keywords
polymorphisms
nucleotide sequence
mutations
present
specific region
Prior art date
Application number
AT00971828T
Other languages
English (en)
Inventor
Hidetoshi Kanda
Tsugunori Notomi
Kentaro Nagamine
Toshihiro Yonekawa
Original Assignee
Eiken Chemical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1999/006213 external-priority patent/WO2000028082A1/ja
Application filed by Eiken Chemical filed Critical Eiken Chemical
Application granted granted Critical
Publication of ATE317023T1 publication Critical patent/ATE317023T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Holo Graphy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT00971828T 1999-11-08 2000-11-07 Methode zum nachweis von variationen oder polymorphismen ATE317023T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/JP1999/006213 WO2000028082A1 (fr) 1998-11-09 1999-11-08 Procede de synthese d'acide nucleique
JP2000134334 2000-04-28

Publications (1)

Publication Number Publication Date
ATE317023T1 true ATE317023T1 (de) 2006-02-15

Family

ID=26440202

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00971828T ATE317023T1 (de) 1999-11-08 2000-11-07 Methode zum nachweis von variationen oder polymorphismen

Country Status (8)

Country Link
US (1) US7175985B1 (de)
EP (1) EP1231281B1 (de)
CN (2) CN1415020A (de)
AT (1) ATE317023T1 (de)
AU (1) AU1057801A (de)
DE (1) DE60025840T2 (de)
ES (1) ES2258027T3 (de)
WO (1) WO2001034838A1 (de)

Families Citing this family (37)

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US6743605B1 (en) 1998-06-24 2004-06-01 Enzo Life Sciences, Inc. Linear amplification of specific nucleic acid sequences
US8445664B2 (en) 1998-06-24 2013-05-21 Enzo Diagnostics, Inc. Kits for amplifying and detecting nucleic acid sequences
WO2001034838A1 (en) * 1999-11-08 2001-05-17 Eiken Kagaku Kabushiki Kaisha Method of detecting variation or polymorphism
CN100422323C (zh) * 2000-04-07 2008-10-01 荣研化学株式会社 使用双链核酸为模板扩增核酸的方法
DE60139331D1 (de) * 2000-09-19 2009-09-03 Eiken Chemical Verfahren zur polynukleotidsynthese
JP2002345499A (ja) * 2001-05-29 2002-12-03 Eiken Chem Co Ltd 核酸配列を検出する方法及びその方法に使用するキット
GB0218215D0 (en) * 2002-08-06 2002-09-11 Tepnel Medical Ltd Amplification of nucleic acids
WO2004022743A1 (ja) * 2002-09-06 2004-03-18 Wakunaga Pharmaceutical Co., Ltd. 多型配列部位を有する核酸の識別方法
AU2003280603A1 (en) * 2002-10-29 2004-05-25 Kabushiki Kaisha Dnaform Method of amplifying nucleic acid
JP3897805B2 (ja) * 2003-12-25 2007-03-28 独立行政法人理化学研究所 核酸の増幅法およびこれを利用した変異核酸の検出法
US7888014B2 (en) * 2004-10-19 2011-02-15 Nihon University Method of detecting Haemophilus influenzae type b, primer set and kit for the use in the method
JP2008029333A (ja) * 2006-07-03 2008-02-14 Fujifilm Corp 新規遺伝子増幅法に用いられるプライマー
EP2108048A1 (de) 2007-01-17 2009-10-14 Meridian Bioscience, Inc. Stabile reagenzien und kits für loop-vermittelte isotherme verstärkung
CA2622649C (en) 2007-03-09 2018-04-24 Riken Nucleic acid amplification method using primer exhibiting exciton effect
JP4410268B2 (ja) * 2007-03-28 2010-02-03 株式会社東芝 メチレンテトラヒドロ葉酸還元酵素（ｍｔｈｆｒ）の遺伝子型を検出するための核酸プライマーセット及び核酸プローブ
WO2009049630A1 (en) * 2007-10-16 2009-04-23 Aarhus Universitet Isothermal amplification method for detection of nucleic acid mutation
US20100221787A1 (en) 2007-10-25 2010-09-02 Riken Isothermal amplification method and dna polymerase used in the same
JP5530185B2 (ja) * 2008-02-05 2014-06-25 オリンパス株式会社 核酸検出方法及び核酸検出用キット
US20110236900A1 (en) 2008-11-27 2011-09-29 Riken Novel muts protein and method for determing mutation using the same
WO2010075249A2 (en) 2008-12-22 2010-07-01 Genentech, Inc. A method for treating rheumatoid arthritis with b-cell antagonists
EP2272980A1 (de) * 2009-07-09 2011-01-12 Bioesplora SRL Molekulare Sonden zum Nachweis und zur Quantifizierung von Target-Nukleinsäure
EP2272978B1 (de) 2009-07-10 2012-04-18 Biotrin International Limited Hochsensibles schnelles isothermisches Verfahren zur Detektion von Punktmutationen und SNPs
JP2013518590A (ja) 2010-02-02 2013-05-23 アボツト・バイオテクノロジー・リミテツド ＴＮＦ−α阻害剤を用いる処置に対する応答性を予測するための方法および組成物
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
EP3974831A1 (de) 2010-10-22 2022-03-30 T2 Biosystems, Inc. Verfahren zum nachweis eines bakteriums in einer vollblutprobe
TWI600766B (zh) * 2012-08-09 2017-10-01 財團法人工業技術研究院 用於偵測一目標核苷酸序列中之一特定區域的一突變及／或多形性的套組
US20170335382A1 (en) * 2014-11-10 2017-11-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Isothermal Amplification Assay for the Detection of Short Nucleic Acid Sequences
CN104573409B (zh) * 2015-01-04 2017-07-25 杭州和壹基因科技有限公司 基因定位的多重检验方法
US11326213B2 (en) 2015-01-21 2022-05-10 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of tick-borne pathogens
US20190032104A1 (en) 2016-01-21 2019-01-31 T2 Biosystems, Inc. Rapid antimicrobial susceptibility testing using high-sensitivity direct detection methods
US12077810B2 (en) 2016-04-14 2024-09-03 T2 Biosystems, Inc. Methods and systems for amplification in complex samples
JP7176682B2 (ja) 2018-02-22 2022-11-22 佐藤製薬株式会社 白癬菌の遺伝子をｌａｍｐ法により検出するためのプライマーセット及びそれを含むキット並びにそれらを用いて白癬菌を検出する方法
US11149320B1 (en) 2020-03-31 2021-10-19 Diasorin S.P.A. Assays for the detection of SARS-CoV-2
CN115109840B (zh) * 2021-03-18 2025-08-12 厦门大学 一种分析目标核酸中突变的存在及其类型的方法
CN116024315B (zh) * 2022-11-30 2025-09-09 温州医科大学 一种基于链置换反应的多价双锁钥系统及其在核苷酸多态性检测中的应用
WO2025143218A1 (ja) * 2023-12-28 2025-07-03 デンカ株式会社 変異の解析において使用する較正用基準物質としてのゲノムｄｎａを製造する方法、並びに、ゲノムｄｎａ、細胞、及び標的配列の変異を解析する方法
GB202501167D0 (en) 2025-01-27 2025-03-12 Genomtec Sa A method for detecting nucleotide varients in a nucleic acid sequence

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GB9001181D0 (en) * 1990-01-18 1990-03-21 Imp Cancer Res Tech Genetic assay
US5595891A (en) 1990-07-19 1997-01-21 Behringwerke Ag Method for producing a polynucleotide for use in single primer amplification
US5525462A (en) 1991-05-02 1996-06-11 Toyo Boseki Kabushiki Kaisha Nucleic acid sequence amplification method, detection method, and reagent kit therefor
ES2112302T3 (es) * 1991-10-11 1998-04-01 Behringwerke Ag Metodo para producir un polinucleotido para uso en amplificacion con un unico cebador y oligonucleotidos que contienen fosforotioato como cebadores para la amplificacion de acidos nucleicos.
US5612199A (en) 1991-10-11 1997-03-18 Behringwerke Ag Method for producing a polynucleotide for use in single primer amplification
US5270184A (en) 1991-11-19 1993-12-14 Becton, Dickinson And Company Nucleic acid target generation
FR2721945B1 (fr) * 1994-07-04 1996-10-18 David Fabrice Accroissement genique, un procede d'amplicication genique isotherme et ses applications
FR2726277B1 (fr) * 1994-10-28 1996-12-27 Bio Merieux Oligonucleotide utilisable comme amorce dans une methode d'amplification basee sur une replication avec deplacement de brin
AT402203B (de) 1995-06-13 1997-03-25 Himmler Gottfried Dipl Ing Dr Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren
US5888731A (en) 1995-08-30 1999-03-30 Visible Genetics Inc. Method for identification of mutations using ligation of multiple oligonucleotide probes
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6743605B1 (en) * 1998-06-24 2004-06-01 Enzo Life Sciences, Inc. Linear amplification of specific nucleic acid sequences
EP1020534B2 (de) * 1998-11-09 2011-01-05 Eiken Kagaku Kabushiki Kaisha Verfahren zur synthese von nukleinsäuren
US6277607B1 (en) * 1999-05-24 2001-08-21 Sanjay Tyagi High specificity primers, amplification methods and kits
US20020025519A1 (en) * 1999-06-17 2002-02-28 David J. Wright Methods and oligonucleotides for detecting nucleic acid sequence variations
WO2001034838A1 (en) * 1999-11-08 2001-05-17 Eiken Kagaku Kabushiki Kaisha Method of detecting variation or polymorphism

Also Published As

Publication number Publication date
ES2258027T3 (es) 2006-08-16
EP1231281A4 (de) 2003-05-14
DE60025840D1 (de) 2006-04-13
CN1415020A (zh) 2003-04-30
AU1057801A (en) 2001-06-06
US7175985B1 (en) 2007-02-13
WO2001034838A1 (en) 2001-05-17
EP1231281B1 (de) 2006-02-01
EP1231281A1 (de) 2002-08-14
DE60025840T2 (de) 2006-07-27
CN1876843A (zh) 2006-12-13
CN1876843B (zh) 2012-09-05

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