DE60219132D1 - Mutationsanalyse Mittels PCR und Massenspektrometrie - Google Patents
Mutationsanalyse Mittels PCR und MassenspektrometrieInfo
- Publication number
- DE60219132D1 DE60219132D1 DE60219132T DE60219132T DE60219132D1 DE 60219132 D1 DE60219132 D1 DE 60219132D1 DE 60219132 T DE60219132 T DE 60219132T DE 60219132 T DE60219132 T DE 60219132T DE 60219132 D1 DE60219132 D1 DE 60219132D1
- Authority
- DE
- Germany
- Prior art keywords
- pcr
- primers
- linkers
- analysis
- mass spectrometric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02002522A EP1333101B1 (de) | 2002-02-01 | 2002-02-01 | Mutationsanalyse Mittels PCR und Massenspektrometrie |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60219132D1 true DE60219132D1 (de) | 2007-05-10 |
DE60219132T2 DE60219132T2 (de) | 2007-12-13 |
Family
ID=8185417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60219132T Expired - Lifetime DE60219132T2 (de) | 2002-02-01 | 2002-02-01 | Mutationsanalyse mittels PCR und Massenspektrometrie |
Country Status (4)
Country | Link |
---|---|
US (1) | US6750022B2 (de) |
EP (1) | EP1333101B1 (de) |
AT (1) | ATE358185T1 (de) |
DE (1) | DE60219132T2 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10108453B4 (de) * | 2001-02-22 | 2005-10-20 | Bruker Daltonik Gmbh | Massenspektrometrische Mutationsanalyse mit photolytisch spaltbaren Primern |
US20030027135A1 (en) | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
US7666588B2 (en) | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
US20040121309A1 (en) | 2002-12-06 | 2004-06-24 | Ecker David J. | Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues |
US7226739B2 (en) | 2001-03-02 | 2007-06-05 | Isis Pharmaceuticals, Inc | Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations |
US7718354B2 (en) | 2001-03-02 | 2010-05-18 | Ibis Biosciences, Inc. | Methods for rapid identification of pathogens in humans and animals |
US7217510B2 (en) | 2001-06-26 | 2007-05-15 | Isis Pharmaceuticals, Inc. | Methods for providing bacterial bioagent characterizing information |
US8073627B2 (en) | 2001-06-26 | 2011-12-06 | Ibis Biosciences, Inc. | System for indentification of pathogens |
JP2006516193A (ja) | 2002-12-06 | 2006-06-29 | アイシス・ファーマシューティカルス・インコーポレーテッド | ヒトおよび動物における病原体の迅速な同定方法 |
US8046171B2 (en) | 2003-04-18 | 2011-10-25 | Ibis Biosciences, Inc. | Methods and apparatus for genetic evaluation |
US8057993B2 (en) | 2003-04-26 | 2011-11-15 | Ibis Biosciences, Inc. | Methods for identification of coronaviruses |
US8158354B2 (en) | 2003-05-13 | 2012-04-17 | Ibis Biosciences, Inc. | Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
US7964343B2 (en) | 2003-05-13 | 2011-06-21 | Ibis Biosciences, Inc. | Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture |
US8546082B2 (en) | 2003-09-11 | 2013-10-01 | Ibis Biosciences, Inc. | Methods for identification of sepsis-causing bacteria |
US8097416B2 (en) | 2003-09-11 | 2012-01-17 | Ibis Biosciences, Inc. | Methods for identification of sepsis-causing bacteria |
US20120122101A1 (en) | 2003-09-11 | 2012-05-17 | Rangarajan Sampath | Compositions for use in identification of bacteria |
US7666592B2 (en) | 2004-02-18 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for concurrent identification and quantification of an unknown bioagent |
US8119336B2 (en) | 2004-03-03 | 2012-02-21 | Ibis Biosciences, Inc. | Compositions for use in identification of alphaviruses |
JP4810533B2 (ja) | 2004-05-24 | 2011-11-09 | アイビス バイオサイエンシズ インコーポレイティッド | ディジタルスレショルド化による選択的イオン濾過作用を用いた質量分光測定法 |
US20050266411A1 (en) | 2004-05-25 | 2005-12-01 | Hofstadler Steven A | Methods for rapid forensic analysis of mitochondrial DNA |
US7811753B2 (en) | 2004-07-14 | 2010-10-12 | Ibis Biosciences, Inc. | Methods for repairing degraded DNA |
WO2006135400A2 (en) | 2004-08-24 | 2006-12-21 | Isis Pharmaceuticals, Inc. | Methods for rapid identification of recombinant organisms |
US8084207B2 (en) | 2005-03-03 | 2011-12-27 | Ibis Bioscience, Inc. | Compositions for use in identification of papillomavirus |
CA2600184A1 (en) | 2005-03-03 | 2006-09-08 | Isis Pharmaceuticals, Inc. | Compositions for use in identification of adventitious viruses |
JP2009502137A (ja) | 2005-07-21 | 2009-01-29 | アイシス ファーマシューティカルズ インコーポレイティッド | 核酸変種の迅速な同定および定量のための方法 |
GB0601031D0 (en) * | 2006-01-18 | 2006-03-01 | Novartis Ag | Organic compounds |
WO2007115059A2 (en) | 2006-03-29 | 2007-10-11 | Merial Limited | Vaccine against streptococci |
EP2010679A2 (de) | 2006-04-06 | 2009-01-07 | Ibis Biosciences, Inc. | Zusammensetzungen für die identifizierung von pilzen |
CA2663029C (en) | 2006-09-14 | 2016-07-19 | Ibis Biosciences, Inc. | Targeted whole genome amplification method for identification of pathogens |
EP2126132B1 (de) | 2007-02-23 | 2013-03-20 | Ibis Biosciences, Inc. | Verfahren für schnelle forensische dna-analyse |
US9598724B2 (en) | 2007-06-01 | 2017-03-21 | Ibis Biosciences, Inc. | Methods and compositions for multiple displacement amplification of nucleic acids |
WO2010033627A2 (en) | 2008-09-16 | 2010-03-25 | Ibis Biosciences, Inc. | Sample processing units, systems, and related methods |
US8550694B2 (en) | 2008-09-16 | 2013-10-08 | Ibis Biosciences, Inc. | Mixing cartridges, mixing stations, and related kits, systems, and methods |
WO2010033625A1 (en) | 2008-09-16 | 2010-03-25 | Ibis Biosciences, Inc. | Microplate handling systems and related computer program products and methods |
EP2396803A4 (de) | 2009-02-12 | 2016-10-26 | Ibis Biosciences Inc | Ionisationssondenanordnungen |
WO2010104798A1 (en) | 2009-03-08 | 2010-09-16 | Ibis Biosciences, Inc. | Bioagent detection methods |
WO2010114842A1 (en) | 2009-03-30 | 2010-10-07 | Ibis Biosciences, Inc. | Bioagent detection systems, devices, and methods |
WO2011008971A1 (en) | 2009-07-17 | 2011-01-20 | Ibis Biosciences, Inc. | Lift and mount apparatus |
EP2454000A4 (de) | 2009-07-17 | 2016-08-10 | Ibis Biosciences Inc | Systeme zur identifizierung von biowirkstoffen |
WO2011014811A1 (en) | 2009-07-31 | 2011-02-03 | Ibis Biosciences, Inc. | Capture primers and capture sequence linked solid supports for molecular diagnostic tests |
US9080209B2 (en) | 2009-08-06 | 2015-07-14 | Ibis Biosciences, Inc. | Non-mass determined base compositions for nucleic acid detection |
US9890408B2 (en) | 2009-10-15 | 2018-02-13 | Ibis Biosciences, Inc. | Multiple displacement amplification |
WO2011115840A2 (en) | 2010-03-14 | 2011-09-22 | Ibis Biosciences, Inc. | Parasite detection via endosymbiont detection |
WO2018013999A1 (en) | 2016-07-15 | 2018-01-18 | Am Chemicals Llc | Non-nucleosidic solid supports and phosphoramidite building blocks for oligonucleotide synthesis |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5605798A (en) * | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
US5541405A (en) | 1994-07-27 | 1996-07-30 | Parker-Hannifin Corporation | Method and device for continuous pattern sensing using fiber optics |
GB9504598D0 (en) | 1995-03-03 | 1995-04-26 | Imp Cancer Res Tech | Method of nucleic acid analysis |
US6291172B1 (en) * | 1995-03-03 | 2001-09-18 | Mitokor | Diagnostic assay for diabetes mellitus based on mutational burden |
US5830655A (en) * | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
US5869242A (en) * | 1995-09-18 | 1999-02-09 | Myriad Genetics, Inc. | Mass spectrometry to assess DNA sequence polymorphisms |
US5789166A (en) * | 1995-12-08 | 1998-08-04 | Stratagene | Circular site-directed mutagenesis |
PT840804E (pt) * | 1996-01-23 | 2000-10-31 | Qiagen Genomics Inc | Metodos e composicoes para a analise de moleculas de acidos nocleicos usando tecnicas de separacao por dimensoes |
EP0886681A1 (de) * | 1996-03-04 | 1998-12-30 | Genetrace Systems, Inc. | Verfahren zur suche von nukleinsäuren mit massenspektroskopie |
WO1998054571A1 (en) * | 1997-05-28 | 1998-12-03 | The Walter And Eliza Hall Institute Of Medical Research | Nucleic acid diagnostics based on mass spectrometry or mass separation and base specific cleavage |
DE10015797B4 (de) * | 2000-03-26 | 2006-02-02 | Bruker Daltonik Gmbh | Multiplex-Analyse von DNA-Gemischen mittels photolytisch ablesbarer DNA-Chips |
-
2002
- 2002-02-01 AT AT02002522T patent/ATE358185T1/de not_active IP Right Cessation
- 2002-02-01 DE DE60219132T patent/DE60219132T2/de not_active Expired - Lifetime
- 2002-02-01 EP EP02002522A patent/EP1333101B1/de not_active Expired - Lifetime
- 2002-02-20 US US10/079,271 patent/US6750022B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE358185T1 (de) | 2007-04-15 |
EP1333101A1 (de) | 2003-08-06 |
DE60219132T2 (de) | 2007-12-13 |
EP1333101B1 (de) | 2007-03-28 |
US20030148293A1 (en) | 2003-08-07 |
US6750022B2 (en) | 2004-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |