ATE305794T1 - Prozess zur herstellung eines matrin enthaltenden pflanzenextrakts - Google Patents

Prozess zur herstellung eines matrin enthaltenden pflanzenextrakts

Info

Publication number
ATE305794T1
ATE305794T1 AT02702393T AT02702393T ATE305794T1 AT E305794 T1 ATE305794 T1 AT E305794T1 AT 02702393 T AT02702393 T AT 02702393T AT 02702393 T AT02702393 T AT 02702393T AT E305794 T1 ATE305794 T1 AT E305794T1
Authority
AT
Austria
Prior art keywords
producing
plant extract
extract containing
containing matrine
matrine
Prior art date
Application number
AT02702393T
Other languages
English (en)
Inventor
John Wah Tze
Peizhong Lin
Stephen Lam
Joseph Tai
Frisi Hobbe Smit
Helvoort Adrianus Lambertu Van
Robert Johan Joseph Hageman
Theresa P Chiang Tze
Original Assignee
Global Cancer Strategies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Global Cancer Strategies Ltd filed Critical Global Cancer Strategies Ltd
Application granted granted Critical
Publication of ATE305794T1 publication Critical patent/ATE305794T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Fertilizers (AREA)
AT02702393T 2001-02-26 2002-02-26 Prozess zur herstellung eines matrin enthaltenden pflanzenextrakts ATE305794T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/793,251 US20030099725A1 (en) 2001-02-26 2001-02-26 Herbal compositions useful as chemopreventive and therapeutic agents and methods of manufacturing same
PCT/EP2002/002350 WO2002067955A2 (en) 2001-02-26 2002-02-26 A process for the manufacture of a herbal composition comprising a matrine

Publications (1)

Publication Number Publication Date
ATE305794T1 true ATE305794T1 (de) 2005-10-15

Family

ID=25159475

Family Applications (3)

Application Number Title Priority Date Filing Date
AT02702393T ATE305794T1 (de) 2001-02-26 2002-02-26 Prozess zur herstellung eines matrin enthaltenden pflanzenextrakts
AT02711728T ATE304368T1 (de) 2001-02-26 2002-02-26 Kräuterpflanzen enthaltende artzneimittel
AT02711729T ATE397936T1 (de) 2001-02-26 2002-02-26 Therapeutische verfahren unter verwendung von pflanzlichen zusammensetzungen

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT02711728T ATE304368T1 (de) 2001-02-26 2002-02-26 Kräuterpflanzen enthaltende artzneimittel
AT02711729T ATE397936T1 (de) 2001-02-26 2002-02-26 Therapeutische verfahren unter verwendung von pflanzlichen zusammensetzungen

Country Status (11)

Country Link
US (5) US20030099725A1 (de)
EP (4) EP1363651B1 (de)
JP (1) JP2004529885A (de)
CN (1) CN1585647A (de)
AT (3) ATE305794T1 (de)
AU (2) AU2002231544A1 (de)
CA (1) CA2439301A1 (de)
DE (3) DE60206474T2 (de)
DK (1) DK1370271T3 (de)
HK (2) HK1060694A1 (de)
WO (4) WO2002067961A2 (de)

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WO2004054592A1 (en) * 2002-12-13 2004-07-01 Gobind Prasad Dubey Herbal preparation for management of cardiovascular and neurologic disorders
US8668908B2 (en) * 2002-12-31 2014-03-11 National Yang-Ming University Method for alleviating chemotherapy side effects using extract of Dioscorea sp
US20060068036A1 (en) 2002-12-31 2006-03-30 National Yang-Ming University Extract of Dioscorea sp. and the medical uses thereof
GB0317020D0 (en) * 2003-07-21 2003-08-27 Sahajanand Biotech Private Ltd Herbo-mineral formulation for refractory leukemias and lymphomas
US20050025823A1 (en) * 2003-07-29 2005-02-03 Fong Andy A.T. Methods of use of herbal compositions
US20060008540A1 (en) * 2004-07-08 2006-01-12 Rulin Xiu Herbal compositions comprising portaluca
US20060024391A1 (en) * 2004-07-30 2006-02-02 Lak Zarahmehran S Dietary nutritional suppliments for persons smoking tobacco products
US7368133B2 (en) * 2004-08-23 2008-05-06 Yu Ching Wu Medicinal drug and methods of manufacturing the same
US7384657B2 (en) * 2004-10-14 2008-06-10 Jeffrey Young Composition of natural herb extract for treating cardiovascular disease and its method of preparation thereof
WO2006066354A1 (en) * 2004-12-24 2006-06-29 Dolphst Pty Ltd Formula ions and treatments for well-being
WO2007012335A1 (fr) * 2005-07-26 2007-02-01 Djamila Souiki Traitement de tout types de cancer, kystes, fibromes, des infections, inflammations, anxiete, migraines, desequilibre hormonal, ulcere, asthme, maladie de crohne, eczema, psoriasis, rhumatisme, acne.
CN100431581C (zh) * 2006-01-20 2008-11-12 丽珠医药集团股份有限公司 治疗禽流感的中药组合物、制备方法及其用途
US20070202215A1 (en) * 2006-02-28 2007-08-30 Zahramehran Salari Lak Dietary nutritional supplements for persons consuming alcohol products
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US20090011060A1 (en) * 2007-07-06 2009-01-08 Peter Koepke Campsiandra angustifolia extract and methods of extracting and using such extract
US7879369B2 (en) 2007-09-18 2011-02-01 Selvamedica, Llc Combretum laurifolium Mart. extract and methods of extracting and using such extract
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KR20120080674A (ko) * 2011-01-08 2012-07-18 주식회사한국전통의학연구소 대계근 추출물을 포함하는 백혈병 치료용 조성물 및 건강 기능성 식품
CN102091049B (zh) * 2011-01-17 2015-12-02 广东东阳光药业有限公司 一种苦参碱分散片及其制备工艺
CN103127057A (zh) * 2011-11-25 2013-06-05 复旦大学 梣酮在制备抗肿瘤药物中的应用
CN102532147B (zh) * 2011-12-30 2014-05-21 山东省分析测试中心 高纯度白鲜碱单体的制备方法
CN102641454B (zh) * 2012-05-22 2014-01-01 江苏省中医药研究院 一种治疗慢性萎缩性胃炎的中药组合物
CN103630630B (zh) * 2013-12-16 2014-11-19 广西大学 一种山豆根药材中苦参碱的含量测定方法
CN104887834A (zh) * 2014-03-04 2015-09-09 苏州益福康材料科技有限公司 一种用于治疗或预防哺乳动物癌症和其他疾病的包含苦参碱的组合物
CN104887684A (zh) * 2014-03-07 2015-09-09 复旦大学 雅姆皂苷元在制备抗肿瘤药物中的应用
CN105250743A (zh) * 2015-09-17 2016-01-20 连艳芬 一种治疗肺癌中药
CN105769880B (zh) 2016-03-09 2018-05-15 广东省中医院 黄柏酮在制备防治肺损伤和肺纤维化的药物中的应用
CN106526057B (zh) * 2016-09-22 2017-12-05 广东东阳光药业有限公司 一种检测珠芽蓼中黄酮类成分的薄层色谱分析方法
CN112437660B (zh) * 2018-06-01 2024-06-14 耶鲁大学 治疗类固醇激素相关疾病或障碍的组合物和方法
CN108815435A (zh) * 2018-08-31 2018-11-16 陕西石宇药业有限公司 一种治疗瘙痒性皮肤病的中药组合物及其制剂的制备方法
CN110960668A (zh) * 2018-09-28 2020-04-07 上海市浦东新区浦南医院 一种用于预防和治疗肝病的组合物及其应用
KR102236022B1 (ko) * 2019-06-24 2021-04-05 계명대학교 산학협력단 사데풀 추출물을 유효성분으로 함유하는 피부 미백 또는 주름개선용 조성물
CN110354010A (zh) * 2019-07-24 2019-10-22 石家庄市中医院 一种具有抗幽门螺杆菌功效的漱口水
CN110297060B (zh) * 2019-07-25 2021-09-17 广西中医药大学 一种山苦荬药材指纹图谱检测方法及其指纹图谱
KR102093073B1 (ko) * 2019-08-30 2020-03-24 국립해양생물자원관 사데풀 추출물을 유효성분으로 함유하는 항염증용 조성물
US20230165923A1 (en) * 2020-03-17 2023-06-01 Epidarus Therapeutics, Llc Compositions for inhibiting degradation of hyaluronic acid and methods of use thereof
CN111317734A (zh) * 2020-03-27 2020-06-23 广州医科大学附属第二医院 Wnt信号通路抑制剂和应用
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CN114246868B (zh) * 2021-12-24 2023-06-06 中国人民解放军军事科学院军事医学研究院 一种尿路感染病原体尿路致病性大肠杆菌的抑制剂
CN114271144A (zh) * 2021-12-31 2022-04-05 张宇希 一种杉树下种植南板蓝根的方法
CN114259488A (zh) * 2022-01-27 2022-04-01 杭州师范大学 中药分子梣酮在制备治疗神经胶质瘤药物上的应用
CN115192571A (zh) * 2022-07-11 2022-10-18 中国人民解放军总医院第五医学中心 化合物Rutaevin在制备治疗胃癌药物中的应用
CN115778888B (zh) * 2023-02-10 2023-04-28 云南云科特色植物提取实验室有限公司 一种白及提取物的制备方法及其产品和应用

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Also Published As

Publication number Publication date
EP1370271A2 (de) 2003-12-17
CN1585647A (zh) 2005-02-23
DE60206137D1 (de) 2005-10-20
ATE304368T1 (de) 2005-09-15
EP1363651B1 (de) 2005-09-14
JP2004529885A (ja) 2004-09-30
WO2002067960A1 (en) 2002-09-06
DE60206137T2 (de) 2006-07-27
HK1060694A1 (en) 2004-08-20
DE60206474D1 (de) 2005-11-10
US20050025841A1 (en) 2005-02-03
WO2002067961A2 (en) 2002-09-06
EP1392334B1 (de) 2008-06-11
US20040192579A1 (en) 2004-09-30
EP1370271B1 (de) 2005-10-05
US20060165816A1 (en) 2006-07-27
AU2002235930A1 (en) 2002-09-12
DE60206474T2 (de) 2006-07-13
CA2439301A1 (en) 2002-09-19
EP1370274A1 (de) 2003-12-17
WO2002067955A3 (en) 2002-11-07
EP1363651A1 (de) 2003-11-26
HK1061203A1 (en) 2004-09-10
WO2002067961A3 (en) 2003-05-15
US20030099725A1 (en) 2003-05-29
EP1392334A2 (de) 2004-03-03
WO2002072120A1 (en) 2002-09-19
DE60227068D1 (de) 2008-07-24
AU2002231544A1 (en) 2002-09-12
DK1370271T3 (da) 2006-02-20
WO2002067955A2 (en) 2002-09-06
US20040170704A1 (en) 2004-09-02
ATE397936T1 (de) 2008-07-15

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