HK1061203A1 - A process for the manufacture of a herbal composition comprising a matrine - Google Patents

A process for the manufacture of a herbal composition comprising a matrine

Info

Publication number
HK1061203A1
HK1061203A1 HK04104308A HK04104308A HK1061203A1 HK 1061203 A1 HK1061203 A1 HK 1061203A1 HK 04104308 A HK04104308 A HK 04104308A HK 04104308 A HK04104308 A HK 04104308A HK 1061203 A1 HK1061203 A1 HK 1061203A1
Authority
HK
Hong Kong
Prior art keywords
matrine
manufacture
herbal composition
chemopreventive
extracts
Prior art date
Application number
HK04104308A
Other languages
English (en)
Inventor
John Wah Tze
Peizhong Lin
Stephen Lam
Joseph Tai
Frisi Hobbe Smit
Adrianus Lambertus Be Helvoort
Robert Johan Joseph Hageman
Tze Theresa P Chiang
Original Assignee
Global Cancer Strategies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Global Cancer Strategies Ltd filed Critical Global Cancer Strategies Ltd
Publication of HK1061203A1 publication Critical patent/HK1061203A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Fertilizers (AREA)
HK04104308A 2001-02-26 2004-06-15 A process for the manufacture of a herbal composition comprising a matrine HK1061203A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/793,251 US20030099725A1 (en) 2001-02-26 2001-02-26 Herbal compositions useful as chemopreventive and therapeutic agents and methods of manufacturing same
PCT/EP2002/002350 WO2002067955A2 (en) 2001-02-26 2002-02-26 A process for the manufacture of a herbal composition comprising a matrine

Publications (1)

Publication Number Publication Date
HK1061203A1 true HK1061203A1 (en) 2004-09-10

Family

ID=25159475

Family Applications (2)

Application Number Title Priority Date Filing Date
HK04103572A HK1060694A1 (en) 2001-02-26 2004-05-20 Herbal compositions useful as chemopreventive and therapeutic agents.
HK04104308A HK1061203A1 (en) 2001-02-26 2004-06-15 A process for the manufacture of a herbal composition comprising a matrine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK04103572A HK1060694A1 (en) 2001-02-26 2004-05-20 Herbal compositions useful as chemopreventive and therapeutic agents.

Country Status (11)

Country Link
US (5) US20030099725A1 (xx)
EP (4) EP1363651B1 (xx)
JP (1) JP2004529885A (xx)
CN (1) CN1585647A (xx)
AT (3) ATE305794T1 (xx)
AU (2) AU2002231544A1 (xx)
CA (1) CA2439301A1 (xx)
DE (3) DE60227068D1 (xx)
DK (1) DK1370271T3 (xx)
HK (2) HK1060694A1 (xx)
WO (4) WO2002072120A1 (xx)

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EP1569666B1 (en) * 2002-12-13 2006-09-27 Gobind Prasad Dubey Herbal preparation for management of cardiovascular and neurologic disorders
US20060068036A1 (en) 2002-12-31 2006-03-30 National Yang-Ming University Extract of Dioscorea sp. and the medical uses thereof
US8668908B2 (en) * 2002-12-31 2014-03-11 National Yang-Ming University Method for alleviating chemotherapy side effects using extract of Dioscorea sp
GB0317020D0 (en) * 2003-07-21 2003-08-27 Sahajanand Biotech Private Ltd Herbo-mineral formulation for refractory leukemias and lymphomas
US20050025823A1 (en) * 2003-07-29 2005-02-03 Fong Andy A.T. Methods of use of herbal compositions
US20060008540A1 (en) * 2004-07-08 2006-01-12 Rulin Xiu Herbal compositions comprising portaluca
US20060024391A1 (en) * 2004-07-30 2006-02-02 Lak Zarahmehran S Dietary nutritional suppliments for persons smoking tobacco products
US7368133B2 (en) * 2004-08-23 2008-05-06 Yu Ching Wu Medicinal drug and methods of manufacturing the same
US7384657B2 (en) * 2004-10-14 2008-06-10 Jeffrey Young Composition of natural herb extract for treating cardiovascular disease and its method of preparation thereof
JP2008525320A (ja) * 2004-12-24 2008-07-17 ドルフィスト・プロプライエタリー・リミテッド 厚生のための配合物及び治療
WO2007012335A1 (fr) * 2005-07-26 2007-02-01 Djamila Souiki Traitement de tout types de cancer, kystes, fibromes, des infections, inflammations, anxiete, migraines, desequilibre hormonal, ulcere, asthme, maladie de crohne, eczema, psoriasis, rhumatisme, acne.
CN100431581C (zh) * 2006-01-20 2008-11-12 丽珠医药集团股份有限公司 治疗禽流感的中药组合物、制备方法及其用途
US20070202215A1 (en) * 2006-02-28 2007-08-30 Zahramehran Salari Lak Dietary nutritional supplements for persons consuming alcohol products
JPWO2007132893A1 (ja) * 2006-05-17 2009-09-24 アークレイ株式会社 Ｍｃｐ−１の発現抑制剤、それを用いた炎症性疾患の改善剤、医薬品、サプリメント、食品、飲料および食品添加剤
US20090011060A1 (en) * 2007-07-06 2009-01-08 Peter Koepke Campsiandra angustifolia extract and methods of extracting and using such extract
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US8535739B2 (en) * 2010-01-28 2013-09-17 George Lowe Sparkle essence system
KR20120080674A (ko) * 2011-01-08 2012-07-18 주식회사한국전통의학연구소 대계근 추출물을 포함하는 백혈병 치료용 조성물 및 건강 기능성 식품
CN102091049B (zh) * 2011-01-17 2015-12-02 广东东阳光药业有限公司 一种苦参碱分散片及其制备工艺
CN103127057A (zh) * 2011-11-25 2013-06-05 复旦大学 梣酮在制备抗肿瘤药物中的应用
CN102532147B (zh) * 2011-12-30 2014-05-21 山东省分析测试中心 高纯度白鲜碱单体的制备方法
CN102641454B (zh) * 2012-05-22 2014-01-01 江苏省中医药研究院 一种治疗慢性萎缩性胃炎的中药组合物
CN103630630B (zh) * 2013-12-16 2014-11-19 广西大学 一种山豆根药材中苦参碱的含量测定方法
CN104887834A (zh) * 2014-03-04 2015-09-09 苏州益福康材料科技有限公司 一种用于治疗或预防哺乳动物癌症和其他疾病的包含苦参碱的组合物
CN104887684A (zh) * 2014-03-07 2015-09-09 复旦大学 雅姆皂苷元在制备抗肿瘤药物中的应用
CN105250743A (zh) * 2015-09-17 2016-01-20 连艳芬 一种治疗肺癌中药
CN105769880B (zh) * 2016-03-09 2018-05-15 广东省中医院 黄柏酮在制备防治肺损伤和肺纤维化的药物中的应用
CN106526057B (zh) * 2016-09-22 2017-12-05 广东东阳光药业有限公司 一种检测珠芽蓼中黄酮类成分的薄层色谱分析方法
JP7433249B2 (ja) * 2018-06-01 2024-02-19 イエール ユニバーシティ ステロイドホルモンに関連する疾患または障害を処置するための組成物および方法
CN108815435A (zh) * 2018-08-31 2018-11-16 陕西石宇药业有限公司 一种治疗瘙痒性皮肤病的中药组合物及其制剂的制备方法
CN110960668A (zh) * 2018-09-28 2020-04-07 上海市浦东新区浦南医院 一种用于预防和治疗肝病的组合物及其应用
KR102236022B1 (ko) * 2019-06-24 2021-04-05 계명대학교 산학협력단 사데풀 추출물을 유효성분으로 함유하는 피부 미백 또는 주름개선용 조성물
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WO2021188295A1 (en) * 2020-03-17 2021-09-23 Epidarus Therapeutics, Llc Compositions for inhibiting degradation of hyaluronic acid and methods of use thereof
CN111317734A (zh) * 2020-03-27 2020-06-23 广州医科大学附属第二医院 Wnt信号通路抑制剂和应用
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CN114271144A (zh) * 2021-12-31 2022-04-05 张宇希 一种杉树下种植南板蓝根的方法
CN114259488A (zh) * 2022-01-27 2022-04-01 杭州师范大学 中药分子梣酮在制备治疗神经胶质瘤药物上的应用
CN115192571A (zh) * 2022-07-11 2022-10-18 中国人民解放军总医院第五医学中心 化合物Rutaevin在制备治疗胃癌药物中的应用
CN115778888B (zh) * 2023-02-10 2023-04-28 云南云科特色植物提取实验室有限公司 一种白及提取物的制备方法及其产品和应用

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Also Published As

Publication number Publication date
US20050025841A1 (en) 2005-02-03
DE60206474D1 (de) 2005-11-10
ATE397936T1 (de) 2008-07-15
CN1585647A (zh) 2005-02-23
EP1363651A1 (en) 2003-11-26
US20040192579A1 (en) 2004-09-30
DE60227068D1 (de) 2008-07-24
EP1370271A2 (en) 2003-12-17
ATE305794T1 (de) 2005-10-15
DK1370271T3 (da) 2006-02-20
US20060165816A1 (en) 2006-07-27
DE60206474T2 (de) 2006-07-13
HK1060694A1 (en) 2004-08-20
JP2004529885A (ja) 2004-09-30
EP1363651B1 (en) 2005-09-14
WO2002067955A3 (en) 2002-11-07
US20040170704A1 (en) 2004-09-02
WO2002067961A2 (en) 2002-09-06
DE60206137D1 (de) 2005-10-20
US20030099725A1 (en) 2003-05-29
EP1370274A1 (en) 2003-12-17
WO2002067961A3 (en) 2003-05-15
EP1392334A2 (en) 2004-03-03
AU2002231544A1 (en) 2002-09-12
DE60206137T2 (de) 2006-07-27
EP1370271B1 (en) 2005-10-05
CA2439301A1 (en) 2002-09-19
WO2002067955A2 (en) 2002-09-06
EP1392334B1 (en) 2008-06-11
WO2002067960A1 (en) 2002-09-06
ATE304368T1 (de) 2005-09-15
WO2002072120A1 (en) 2002-09-19
AU2002235930A1 (en) 2002-09-12

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