ATE304610T1 - Auf primer verlängerung basierendes verfahren, das nukleotide verwendet, die über spaltbare linker markiert sind - Google Patents
Auf primer verlängerung basierendes verfahren, das nukleotide verwendet, die über spaltbare linker markiert sindInfo
- Publication number
- ATE304610T1 ATE304610T1 AT03710595T AT03710595T ATE304610T1 AT E304610 T1 ATE304610 T1 AT E304610T1 AT 03710595 T AT03710595 T AT 03710595T AT 03710595 T AT03710595 T AT 03710595T AT E304610 T1 ATE304610 T1 AT E304610T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleotide
- primer
- mole
- labeled derivative
- clivable
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title abstract 9
- 125000003729 nucleotide group Chemical group 0.000 abstract 8
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36959902P | 2002-04-04 | 2002-04-04 | |
| SE0201024A SE0201024D0 (sv) | 2002-04-04 | 2002-04-04 | New method |
| PCT/SE2003/000547 WO2003085135A1 (en) | 2002-04-04 | 2003-04-04 | New method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE304610T1 true ATE304610T1 (de) | 2005-09-15 |
Family
ID=28793693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03710595T ATE304610T1 (de) | 2002-04-04 | 2003-04-04 | Auf primer verlängerung basierendes verfahren, das nukleotide verwendet, die über spaltbare linker markiert sind |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050244827A1 (enExample) |
| EP (1) | EP1495137B1 (enExample) |
| JP (1) | JP4230364B2 (enExample) |
| AT (1) | ATE304610T1 (enExample) |
| AU (1) | AU2003214765B2 (enExample) |
| CA (1) | CA2481495C (enExample) |
| DE (1) | DE60301622T2 (enExample) |
| WO (1) | WO2003085135A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9708358B2 (en) | 2000-10-06 | 2017-07-18 | The Trustees Of Columbia University In The City Of New York | Massive parallel method for decoding DNA and RNA |
| EP1790736A3 (en) | 2000-10-06 | 2007-08-15 | The Trustees Of Columbia University In The City Of New York | Massive parallel method for decoding DNA and RNA |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| GB0129012D0 (en) | 2001-12-04 | 2002-01-23 | Solexa Ltd | Labelled nucleotides |
| JP2006509040A (ja) | 2002-08-23 | 2006-03-16 | ソレックサ リミテッド | 修飾されたヌクレオチド |
| US11008359B2 (en) | 2002-08-23 | 2021-05-18 | Illumina Cambridge Limited | Labelled nucleotides |
| US7414116B2 (en) | 2002-08-23 | 2008-08-19 | Illumina Cambridge Limited | Labelled nucleotides |
| EP1594980B2 (en) * | 2003-01-29 | 2017-08-16 | 454 Life Sciences Corporation | Bead emulsion nucleic acid amplification |
| WO2005060345A2 (en) * | 2003-12-22 | 2005-07-07 | Biotage Ab | New method for sequencing-by-synthesis |
| GB0517097D0 (en) | 2005-08-19 | 2005-09-28 | Solexa Ltd | Modified nucleosides and nucleotides and uses thereof |
| US8399188B2 (en) | 2006-09-28 | 2013-03-19 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
| GB2457402B (en) | 2006-12-01 | 2011-10-19 | Univ Columbia | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators |
| EP2207900B1 (en) | 2007-10-19 | 2015-04-29 | The Trustees of Columbia University in the City of New York | Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis |
| EP3431615A3 (en) | 2007-10-19 | 2019-02-20 | The Trustees of Columbia University in the City of New York | Dna sequencing with non-fluorescent nucleotide reversible terminators cleavable label modified nucleotide terminators |
| JP5431352B2 (ja) | 2007-11-28 | 2014-03-05 | ビーエーエスエフ ソシエタス・ヨーロピア | 液体安定剤混合物 |
| CA2714630A1 (en) | 2008-02-07 | 2009-08-13 | Pacific Biosciences Of California, Inc. | Cis reactive oxygen quenchers integrated into linkers |
| US20100255487A1 (en) | 2009-03-27 | 2010-10-07 | Life Technologies Corporation | Methods and apparatus for single molecule sequencing using energy transfer detection |
| US9146248B2 (en) | 2013-03-14 | 2015-09-29 | Intelligent Bio-Systems, Inc. | Apparatus and methods for purging flow cells in nucleic acid sequencing instruments |
| US10648026B2 (en) | 2013-03-15 | 2020-05-12 | The Trustees Of Columbia University In The City Of New York | Raman cluster tagged molecules for biological imaging |
| US9591268B2 (en) | 2013-03-15 | 2017-03-07 | Qiagen Waltham, Inc. | Flow cell alignment methods and systems |
| BR112015022448B1 (pt) | 2013-03-15 | 2020-12-08 | Illumina Cambridge Limited | molécula de nucleotídeo ou nucleosídeo modificado, métodos para preparar o crescimento de polinucleotídeo complementar a polinucleotídeo alvo de fita simples em reação de sequenciação e para determinar a sequência de polinucleotídeo alvo de fita simples e kit |
| JP7091325B2 (ja) * | 2016-11-04 | 2022-06-27 | キアゲン サイエンシーズ, エルエルシー | チオール含有切断試薬および酸化的洗浄液 |
| BR112020010436A2 (pt) * | 2018-01-26 | 2020-11-24 | F. Hoffmann-La Roche Ag | oligonucleotídeo radiomarcado, processos para a preparação de um oligonucleotídeo radiomarcado, uso do oligonucleotídeo radiomarcado, método para determinar a biodistribuição e farmacocinética e oligonucleotídeo |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4910300A (en) * | 1985-12-11 | 1990-03-20 | Chiron Corporation | Method for making nucleic acid probes |
| US5268486A (en) * | 1986-04-18 | 1993-12-07 | Carnegie-Mellon Unversity | Method for labeling and detecting materials employing arylsulfonate cyanine dyes |
| US5783384A (en) * | 1992-01-13 | 1998-07-21 | President And Fellows Of Harvard College | Selection of binding-molecules |
| US5516664A (en) * | 1992-12-23 | 1996-05-14 | Hyman; Edward D. | Enzymatic synthesis of repeat regions of oligonucleotides |
| EP0870832A4 (en) * | 1995-12-27 | 2001-08-22 | Takara Shuzo Co | NEW DNA POLYMERASE |
| US20020055100A1 (en) * | 1997-04-01 | 2002-05-09 | Kawashima Eric H. | Method of nucleic acid sequencing |
| US6485944B1 (en) * | 1997-10-10 | 2002-11-26 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6280947B1 (en) * | 1999-08-11 | 2001-08-28 | Exact Sciences Corporation | Methods for detecting nucleotide insertion or deletion using primer extension |
| DE60044490D1 (de) * | 1999-02-23 | 2010-07-15 | Caliper Life Sciences Inc | Manipulation von mikroteilchen in mikrofluiden systemen |
| US6818395B1 (en) * | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| AU2001265338A1 (en) * | 2000-06-02 | 2001-12-17 | Dna Sciences, Inc. | Primer extension using a mixture of labelled and unlabelled nucleotides |
-
2003
- 2003-04-04 EP EP03710595A patent/EP1495137B1/en not_active Expired - Lifetime
- 2003-04-04 CA CA2481495A patent/CA2481495C/en not_active Expired - Lifetime
- 2003-04-04 DE DE60301622T patent/DE60301622T2/de not_active Expired - Lifetime
- 2003-04-04 WO PCT/SE2003/000547 patent/WO2003085135A1/en not_active Ceased
- 2003-04-04 US US10/510,107 patent/US20050244827A1/en not_active Abandoned
- 2003-04-04 AU AU2003214765A patent/AU2003214765B2/en not_active Expired
- 2003-04-04 AT AT03710595T patent/ATE304610T1/de not_active IP Right Cessation
- 2003-04-04 JP JP2003582312A patent/JP4230364B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005521422A (ja) | 2005-07-21 |
| DE60301622D1 (de) | 2005-10-20 |
| WO2003085135A1 (en) | 2003-10-16 |
| AU2003214765A1 (en) | 2003-10-20 |
| EP1495137A1 (en) | 2005-01-12 |
| US20050244827A1 (en) | 2005-11-03 |
| CA2481495C (en) | 2011-08-30 |
| JP4230364B2 (ja) | 2009-02-25 |
| CA2481495A1 (en) | 2003-10-16 |
| AU2003214765B2 (en) | 2007-07-26 |
| DE60301622T2 (de) | 2006-06-14 |
| EP1495137B1 (en) | 2005-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |