JP2005536210A5 - - Google Patents

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Publication number
JP2005536210A5
JP2005536210A5 JP2004529748A JP2004529748A JP2005536210A5 JP 2005536210 A5 JP2005536210 A5 JP 2005536210A5 JP 2004529748 A JP2004529748 A JP 2004529748A JP 2004529748 A JP2004529748 A JP 2004529748A JP 2005536210 A5 JP2005536210 A5 JP 2005536210A5
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JP
Japan
Prior art keywords
probe
nucleic acid
target nucleic
endonuclease
site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2004529748A
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English (en)
Japanese (ja)
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JP2005536210A (ja
JP4510626B2 (ja
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Priority claimed from PCT/US2003/026133 external-priority patent/WO2004018626A2/en
Publication of JP2005536210A publication Critical patent/JP2005536210A/ja
Publication of JP2005536210A5 publication Critical patent/JP2005536210A5/ja
Application granted granted Critical
Publication of JP4510626B2 publication Critical patent/JP4510626B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004529748A 2002-08-21 2003-08-20 脱塩基部位エンドヌクレアーゼアッセイ Expired - Fee Related JP4510626B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40564202P 2002-08-21 2002-08-21
PCT/US2003/026133 WO2004018626A2 (en) 2002-08-21 2003-08-20 Abasic site endonuclease assay

Publications (3)

Publication Number Publication Date
JP2005536210A JP2005536210A (ja) 2005-12-02
JP2005536210A5 true JP2005536210A5 (enExample) 2006-09-28
JP4510626B2 JP4510626B2 (ja) 2010-07-28

Family

ID=31946911

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004529748A Expired - Fee Related JP4510626B2 (ja) 2002-08-21 2003-08-20 脱塩基部位エンドヌクレアーゼアッセイ

Country Status (6)

Country Link
US (3) US7252940B2 (enExample)
EP (1) EP1543154A4 (enExample)
JP (1) JP4510626B2 (enExample)
AU (1) AU2003274914A1 (enExample)
CA (1) CA2494993A1 (enExample)
WO (1) WO2004018626A2 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1499738T3 (da) 2002-02-21 2008-11-17 Asm Scient Inc Recombinase-polymerease-amplifikation
US7399590B2 (en) 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
US8030000B2 (en) 2002-02-21 2011-10-04 Alere San Diego, Inc. Recombinase polymerase amplification
US7252940B2 (en) * 2002-08-21 2007-08-07 Epoch Biosciences, Inc. Abasic site endonuclease assay
ES2420831T3 (es) 2005-07-25 2013-08-27 Alere San Diego, Inc. Procedimientos para multiplexar la ampliación de la recombinasa polimerasa
US9121056B2 (en) * 2006-04-28 2015-09-01 Igor Kutyavin Use of products of PCR amplification carrying elements of secondary structure to improve PCR-based nucleic acid detection
WO2007127992A2 (en) 2006-04-28 2007-11-08 Igor Kutyavin Use of base-modified deoxynucleoside triphosphates
US8071308B2 (en) 2006-05-04 2011-12-06 Alere San Diego, Inc. Recombinase polymerase amplification
WO2008002920A2 (en) * 2006-06-26 2008-01-03 Epoch Biosciences, Inc. Methods for generating target nucleic acid sequences
US7727745B2 (en) * 2006-08-14 2010-06-01 Bio-Id Diagnostic Inc. Synthesis of single-stranded DNA
JP5088034B2 (ja) * 2006-08-14 2012-12-05 ソニー株式会社 物質の検出等に有用な核酸鎖とその方法
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
GB0703996D0 (en) * 2007-03-01 2007-04-11 Oxitec Ltd Nucleic acid detection
US8143006B2 (en) * 2007-08-03 2012-03-27 Igor Kutyavin Accelerated cascade amplification (ACA) of nucleic acids comprising strand and sequence specific DNA nicking
EP2195452B1 (en) 2007-08-29 2012-03-14 Sequenom, Inc. Methods and compositions for universal size-specific polymerase chain reaction
WO2010030716A1 (en) * 2008-09-10 2010-03-18 Igor Kutyavin Detection of nucleic acids by oligonucleotide probes cleaved in presence of endonuclease v
US8129149B1 (en) 2008-11-12 2012-03-06 The United States Of America As Represented By The Secretary Of The Army Rapid and sensitive method to measure endonuclease activity
WO2010067055A1 (en) * 2008-12-09 2010-06-17 Oxitec Ltd. Enhanced taqman probe based amplification
CN102428191A (zh) * 2009-03-18 2012-04-25 塞昆纳姆股份有限公司 热稳定性内切核酸酶在产生报道分子中的应用
JP5847076B2 (ja) 2009-05-20 2016-01-20 バイオサイト インコーポレイテッド Ｄｎａグリコシラーゼ／リアーゼおよびａｐエンドヌクレアーゼ基質
ES3022638T3 (en) 2009-06-05 2025-05-28 Abbott Diagnostics Scarborough Inc Recombinase polymerase amplification reagents
US9914963B2 (en) 2009-09-28 2018-03-13 Igor Kutyavin Methods and compositions for detection of nucleic acids based on stabilized oligonucleotide probe complexes
WO2011087707A1 (en) 2009-12-22 2011-07-21 Elitech Holding B.V. Hypertheromostable endonuclease iv substrate probe
JP5961247B2 (ja) 2011-04-07 2016-08-02 アリーア サン ディエゴ， インコーポレイテッド リコンビナーゼポリメラーゼ増幅混合物のモニタリング
CN103890162B (zh) 2011-04-18 2016-08-17 英格朗公司 麦管和用于标记麦管的方法
US8377657B1 (en) 2012-05-15 2013-02-19 Predictive Biosciences Corporation Primers for analyzing methylated sequences and methods of use thereof
AU2013264941B2 (en) * 2012-05-21 2016-12-22 Src, Inc. Methods and systems for the detection of ricin and other ribosome inactivating proteins
EP2971106B1 (en) 2013-03-11 2020-02-26 ELITechGroup, Inc. Methods for true isothermal strand displacement amplification
US10975423B2 (en) 2013-03-11 2021-04-13 Elitechgroup, Inc. Methods for true isothermal strand displacement amplification
WO2016094162A1 (en) 2014-12-12 2016-06-16 Elitechgroup B.V. Methods and compositions for detecting antibiotic resistant bacteria
JP2017538418A (ja) 2014-12-12 2017-12-28 エリテックグループ・ベスローテン・フェンノートシャップＥｌｉｔｅｃｈｇｒｏｕｐ Ｂ．Ｖ． 抗生物質耐性細菌を検出する方法および組成物
US10677728B2 (en) 2017-08-17 2020-06-09 Elitechgroup B.V. Duplex stabilizing fluorescence quenchers for nucleic acid probes
WO2021080629A1 (en) 2019-10-23 2021-04-29 Elitechgroup, Inc. Methods for true isothermal strand displacement amplification
JP2024506277A (ja) * 2021-02-01 2024-02-13 アボット・ラボラトリーズ 脱塩基核酸を有する配列変換及びシグナル増幅ｄｎａ、並びにそれを使用する検出方法
TWI872707B (zh) * 2022-09-15 2025-02-11 呈堯 陳 用於核酸末端標記的方法、套組和系統

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5241060A (en) * 1982-06-23 1993-08-31 Enzo Diagnostics, Inc. Base moiety-labeled detectable nucleatide
US5011769A (en) * 1985-12-05 1991-04-30 Meiogenics U.S. Limited Partnership Methods for detecting nucleic acid sequences
US4876187A (en) * 1985-12-05 1989-10-24 Meiogenics, Inc. Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences
US5403711A (en) * 1987-11-30 1995-04-04 University Of Iowa Research Foundation Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved
EP0439182B1 (en) * 1990-01-26 1996-04-24 Abbott Laboratories Improved method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
US5516663A (en) 1990-01-26 1996-05-14 Abbott Laboratories Ligase chain reaction with endonuclease IV correction and contamination control
US5427930A (en) 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US6582908B2 (en) * 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US5574142A (en) * 1992-12-15 1996-11-12 Microprobe Corporation Peptide linkers for improved oligonucleotide delivery
AU7487294A (en) * 1993-08-18 1995-03-14 Id Biomedical Corporation Compositions and methods for detecting target nucleic acid sequences utilizing flanking sequence enzyme molecules
US5426039A (en) * 1993-09-08 1995-06-20 Bio-Rad Laboratories, Inc. Direct molecular cloning of primer extended DNA containing an alkane diol
WO1995014106A2 (en) * 1993-11-17 1995-05-26 Id Biomedical Corporation Cycling probe cleavage detection of nucleic acid sequences
US5523204A (en) * 1993-12-10 1996-06-04 Becton Dickinson And Company Detection of nucleic acids in cells by strand displacement amplification
US6001610A (en) * 1994-11-23 1999-12-14 Roche Diagnostics, Gmbh Method for the particularly sensitive detection of nucleic acids
JPH08238100A (ja) * 1995-03-03 1996-09-17 Eiken Chem Co Ltd 所定の配列を有する核酸を特異的に検出する方法、並びに該方法に使用されるプローブ及びキット
US5763178A (en) * 1995-06-07 1998-06-09 Trevigen, Inc. Oscillating signal amplifier for nucleic acid detection
US5656430A (en) * 1995-06-07 1997-08-12 Trevigen, Inc. Oscillating signal amplifier for nucleic acid detection
US6190865B1 (en) * 1995-09-27 2001-02-20 Epicentre Technologies Corporation Method for characterizing nucleic acid molecules
US5747255A (en) * 1995-09-29 1998-05-05 Lynx Therapeutics, Inc. Polynucleotide detection by isothermal amplification using cleavable oligonucleotides
JP2000512852A (ja) * 1996-06-17 2000-10-03 バイオダイナミックス アソシエイツ 多成分核酸構築物を調製するための方法及びキット
FR2763600B1 (fr) * 1997-05-20 1999-11-12 Genolife Procede de detection qualitative et quantitative d'alterations de l'adn et des ligands de ces alterations
US6274316B1 (en) * 1997-07-03 2001-08-14 Id Biomedical Corporation Compositions and methods for detecting vancomycin resistant enterococci by cycling probe reactions
AU9381598A (en) * 1997-09-10 1999-03-29 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Method of amplifying dna and rna mismatch cleavage products
JP4388694B2 (ja) * 1998-02-04 2009-12-24 アプライド バイオシステムズ， エルエルシー 複数のアレル部位における増幅産物のゲノム型決定
US5952202A (en) * 1998-03-26 1999-09-14 The Perkin Elmer Corporation Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification
NZ508358A (en) 1998-04-22 2002-07-26 Univ College Cork Nat Univ Ie A method for checking a DNA fragment (target nucleic acid) for the presence or absence of a mutation
US6716971B1 (en) * 1998-09-08 2004-04-06 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pteridine nucleotide analogs
US6268147B1 (en) * 1998-11-02 2001-07-31 Kenneth Loren Beattie Nucleic acid analysis using sequence-targeted tandem hybridization
US6579680B2 (en) * 2000-02-28 2003-06-17 Corning Incorporated Method for label-free detection of hybridized DNA targets
US6340566B1 (en) * 2000-03-28 2002-01-22 The Regents Of The University Of California Detection and quantitation of single nucleotide polymorphisms, DNA sequence variations, DNA mutations, DNA damage and DNA mismatches
US6350580B1 (en) * 2000-10-11 2002-02-26 Stratagene Methods for detection of a target nucleic acid using a probe comprising secondary structure
IE20000887A1 (en) * 2000-11-03 2002-12-11 Univ College Cork Nat Univ Ie Method for the amplification and optional characterisation of nucleic acids
US7252940B2 (en) * 2002-08-21 2007-08-07 Epoch Biosciences, Inc. Abasic site endonuclease assay
US20070020639A1 (en) * 2005-07-20 2007-01-25 Affymetrix, Inc. Isothermal locus specific amplification

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