ATE294818T1 - Modifizierte chimäre superantigene und deren verwendung - Google Patents

Modifizierte chimäre superantigene und deren verwendung

Info

Publication number
ATE294818T1
ATE294818T1 AT97916693T AT97916693T ATE294818T1 AT E294818 T1 ATE294818 T1 AT E294818T1 AT 97916693 T AT97916693 T AT 97916693T AT 97916693 T AT97916693 T AT 97916693T AT E294818 T1 ATE294818 T1 AT E294818T1
Authority
AT
Austria
Prior art keywords
modified
cells
superantigen
subset
replaced
Prior art date
Application number
AT97916693T
Other languages
German (de)
English (en)
Inventor
Per Antonsson
Johan Hansson
Per Bjoerk
Mikael Dohlsten
Terje Kalland
Lars Abrahmsen
Goeran Forsberg
Original Assignee
Active Biotech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9601245A external-priority patent/SE9601245D0/xx
Application filed by Active Biotech Ab filed Critical Active Biotech Ab
Application granted granted Critical
Publication of ATE294818T1 publication Critical patent/ATE294818T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT97916693T 1996-03-29 1997-03-26 Modifizierte chimäre superantigene und deren verwendung ATE294818T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9601245A SE9601245D0 (sv) 1996-03-29 1996-03-29 Chimeric superantigens and their use
US08/695,692 US6514498B1 (en) 1996-03-19 1996-08-12 Modified/chimeric superantigens and their use
PCT/SE1997/000537 WO1997036932A1 (en) 1996-03-29 1997-03-26 Modified/chimeric superantigens and their use

Publications (1)

Publication Number Publication Date
ATE294818T1 true ATE294818T1 (de) 2005-05-15

Family

ID=26662565

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97916693T ATE294818T1 (de) 1996-03-29 1997-03-26 Modifizierte chimäre superantigene und deren verwendung

Country Status (20)

Country Link
US (1) US7226595B2 (https=)
EP (1) EP0835266B1 (https=)
JP (1) JP4114951B2 (https=)
AT (1) ATE294818T1 (https=)
AU (1) AU707827B2 (https=)
BR (1) BR9702179A (https=)
CA (1) CA2222757C (https=)
CZ (1) CZ294475B6 (https=)
DE (1) DE69733179T2 (https=)
ES (1) ES2242222T3 (https=)
HU (1) HU228185B1 (https=)
ID (1) ID16512A (https=)
IL (1) IL122211A (https=)
MX (1) MX9709265A (https=)
NO (1) NO321984B1 (https=)
NZ (1) NZ329145A (https=)
PL (1) PL189696B1 (https=)
PT (1) PT835266E (https=)
TW (1) TW517061B (https=)
WO (1) WO1997036932A1 (https=)

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Also Published As

Publication number Publication date
TW517061B (en) 2003-01-11
US7226595B2 (en) 2007-06-05
IL122211A (en) 2009-07-20
CZ371297A3 (cs) 1998-05-13
NZ329145A (en) 2000-06-23
MX9709265A (es) 1998-03-31
HUP9903444A2 (hu) 2000-02-28
DE69733179D1 (de) 2005-06-09
AU707827B2 (en) 1999-07-22
PL189696B1 (pl) 2005-09-30
IL122211A0 (en) 1998-04-05
PT835266E (pt) 2005-07-29
HUP9903444A3 (en) 2003-08-28
NO975435D0 (no) 1997-11-26
DE69733179T2 (de) 2005-10-06
AU2525197A (en) 1997-10-22
EP0835266A1 (en) 1998-04-15
WO1997036932A1 (en) 1997-10-09
CA2222757C (en) 2011-07-26
CA2222757A1 (en) 1997-10-09
CZ294475B6 (cs) 2005-01-12
NO975435L (no) 1998-01-29
PL323626A1 (en) 1998-04-14
BR9702179A (pt) 1999-03-16
ID16512A (id) 1997-10-02
US20030092894A1 (en) 2003-05-15
NO321984B1 (no) 2006-07-31
EP0835266B1 (en) 2005-05-04
JP4114951B2 (ja) 2008-07-09
ES2242222T3 (es) 2005-11-01
HU228185B1 (en) 2013-01-28
JP2002502363A (ja) 2002-01-22

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