ATE294162T1 - Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid - Google Patents

Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid

Info

Publication number
ATE294162T1
ATE294162T1 AT02767318T AT02767318T ATE294162T1 AT E294162 T1 ATE294162 T1 AT E294162T1 AT 02767318 T AT02767318 T AT 02767318T AT 02767318 T AT02767318 T AT 02767318T AT E294162 T1 ATE294162 T1 AT E294162T1
Authority
AT
Austria
Prior art keywords
lercanidipine hydrochloride
solvates
crystalline forms
lercanidipine
hydrochloride
Prior art date
Application number
AT02767318T
Other languages
English (en)
Inventor
Amedeo Leonardi
Iasi Gianluca De
Fausto Bonifacio
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Application granted granted Critical
Publication of ATE294162T1 publication Critical patent/ATE294162T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02767318T 2001-08-06 2002-08-05 Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid ATE294162T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001MI001727A ITMI20011727A1 (it) 2001-08-06 2001-08-06 Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi
PCT/EP2002/008700 WO2003014085A1 (en) 2001-08-06 2002-08-05 Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride

Publications (1)

Publication Number Publication Date
ATE294162T1 true ATE294162T1 (de) 2005-05-15

Family

ID=11448246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02767318T ATE294162T1 (de) 2001-08-06 2002-08-05 Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid

Country Status (21)

Country Link
EP (1) EP1423367B1 (de)
JP (1) JP2005502648A (de)
KR (1) KR100912664B1 (de)
CN (1) CN100494175C (de)
AR (1) AR037230A1 (de)
AT (1) ATE294162T1 (de)
AU (1) AU2002331390B2 (de)
BR (1) BR0211738A (de)
DE (1) DE60203919D1 (de)
EA (1) EA200400279A1 (de)
ES (1) ES2209684T1 (de)
HR (1) HRP20040157A2 (de)
HU (1) HUP0401161A3 (de)
IL (2) IL153916A0 (de)
IT (1) ITMI20011727A1 (de)
MX (1) MXPA04001073A (de)
NO (1) NO20040479L (de)
PE (1) PE20030350A1 (de)
PL (1) PL369449A1 (de)
UY (1) UY27409A1 (de)
WO (1) WO2003014085A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100651212B1 (ko) 2004-10-27 2006-12-01 제일약품주식회사 무정형 레르카니디핀의 제조방법
AR052918A1 (es) 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
KR20080048065A (ko) 2005-09-16 2008-05-30 그렌마크 파머수티칼스 엘티디. 다형 형태의 염산 레르카니디핀 및 이것의 제조방법
WO2008107797A2 (en) * 2007-03-05 2008-09-12 Actavis Group Ptc Ehf Lercanidipine hydrochloride polymorphs and an improved process for preparation of 1,1,n-trimethyl-n-(3,3-diphenylpropyl)-2-aminoethyl acetoacetate
WO2008136393A1 (ja) * 2007-04-27 2008-11-13 Ajinomoto Co., Inc. ラクタム化合物の結晶形およびその製造方法
WO2011161223A2 (en) 2010-06-23 2011-12-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts
SI2654729T1 (sl) 2010-12-24 2016-08-31 Krka, D.D., Novo Mesto Homogene farmacevtske oralne dozirne oblike, ki obsegajo lerkanidipin in enalapril ali njune farmacevtsko sprejemljive soli skupaj z organsko kislino

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
US5912351A (en) * 1995-05-12 1999-06-15 Recordati, S.A. Chemical And Pharmaceutical Company Anhydrous 1,4-Dihydropyridines and salts thereof

Also Published As

Publication number Publication date
IL153916A0 (en) 2003-07-31
WO2003014085A1 (en) 2003-02-20
CN100494175C (zh) 2009-06-03
DE60203919D1 (de) 2005-06-02
UY27409A1 (es) 2003-03-31
HUP0401161A3 (en) 2009-04-28
AU2002331390B2 (en) 2008-06-05
CN1538958A (zh) 2004-10-20
EP1423367B1 (de) 2005-04-27
KR20040030932A (ko) 2004-04-09
BR0211738A (pt) 2004-09-28
JP2005502648A (ja) 2005-01-27
ES2209684T1 (es) 2004-07-01
AR037230A1 (es) 2004-11-03
PE20030350A1 (es) 2003-06-06
HRP20040157A2 (en) 2004-08-31
EP1423367A1 (de) 2004-06-02
HUP0401161A2 (hu) 2004-09-28
ITMI20011727A0 (it) 2001-08-06
KR100912664B1 (ko) 2009-08-17
NO20040479L (no) 2004-02-03
EA200400279A1 (ru) 2004-06-24
ITMI20011727A1 (it) 2003-02-06
MXPA04001073A (es) 2005-02-17
IL153916A (en) 2008-07-08
PL369449A1 (en) 2005-04-18

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties