ATE294162T1 - Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid - Google Patents
Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochloridInfo
- Publication number
- ATE294162T1 ATE294162T1 AT02767318T AT02767318T ATE294162T1 AT E294162 T1 ATE294162 T1 AT E294162T1 AT 02767318 T AT02767318 T AT 02767318T AT 02767318 T AT02767318 T AT 02767318T AT E294162 T1 ATE294162 T1 AT E294162T1
- Authority
- AT
- Austria
- Prior art keywords
- lercanidipine hydrochloride
- solvates
- crystalline forms
- lercanidipine
- hydrochloride
- Prior art date
Links
- WMFYOYKPJLRMJI-UHFFFAOYSA-N Lercanidipine hydrochloride Chemical compound Cl.COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)CN(C)CCC(C=2C=CC=CC=2)C=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 WMFYOYKPJLRMJI-UHFFFAOYSA-N 0.000 title 2
- 229960002162 lercanidipine hydrochloride Drugs 0.000 title 2
- 239000012453 solvate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001MI001727A ITMI20011727A1 (it) | 2001-08-06 | 2001-08-06 | Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi |
| PCT/EP2002/008700 WO2003014085A1 (en) | 2001-08-06 | 2002-08-05 | Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE294162T1 true ATE294162T1 (de) | 2005-05-15 |
Family
ID=11448246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02767318T ATE294162T1 (de) | 2001-08-06 | 2002-08-05 | Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1423367B1 (de) |
| JP (1) | JP2005502648A (de) |
| KR (1) | KR100912664B1 (de) |
| CN (1) | CN100494175C (de) |
| AR (1) | AR037230A1 (de) |
| AT (1) | ATE294162T1 (de) |
| AU (1) | AU2002331390B2 (de) |
| BR (1) | BR0211738A (de) |
| DE (1) | DE60203919D1 (de) |
| EA (1) | EA200400279A1 (de) |
| ES (1) | ES2209684T1 (de) |
| HR (1) | HRP20040157A2 (de) |
| HU (1) | HUP0401161A3 (de) |
| IL (2) | IL153916A0 (de) |
| IT (1) | ITMI20011727A1 (de) |
| MX (1) | MXPA04001073A (de) |
| NO (1) | NO20040479L (de) |
| PE (1) | PE20030350A1 (de) |
| PL (1) | PL369449A1 (de) |
| UY (1) | UY27409A1 (de) |
| WO (1) | WO2003014085A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100651212B1 (ko) | 2004-10-27 | 2006-12-01 | 제일약품주식회사 | 무정형 레르카니디핀의 제조방법 |
| AR052918A1 (es) | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
| WO2007031865A2 (en) | 2005-09-16 | 2007-03-22 | Glenmark Pharmaceuticals Limited | Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof |
| WO2008107797A2 (en) * | 2007-03-05 | 2008-09-12 | Actavis Group Ptc Ehf | Lercanidipine hydrochloride polymorphs and an improved process for preparation of 1,1,n-trimethyl-n-(3,3-diphenylpropyl)-2-aminoethyl acetoacetate |
| WO2008136394A1 (ja) * | 2007-04-27 | 2008-11-13 | Ajinomoto Co., Inc. | ラクタム化合物の製造方法及びその製造中間体 |
| WO2011161223A2 (en) | 2010-06-23 | 2011-12-29 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts |
| WO2012085249A2 (en) | 2010-12-24 | 2012-06-28 | Krka, D.D., Novo Mesto | Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8403866D0 (en) * | 1984-02-14 | 1984-03-21 | Recordati Chem Pharm | Diphenylalkylaminoalkyl esters |
| US5767136A (en) * | 1995-05-12 | 1998-06-16 | Recordati, S.A. Chemical And Pharmaceutical Company | 1,4-Dihydropyridines useful for prevention or reduction of atherosclerotic lesions on arterial walls |
-
2001
- 2001-08-06 IT IT2001MI001727A patent/ITMI20011727A1/it unknown
-
2002
- 2002-08-02 AR ARP020102957A patent/AR037230A1/es not_active Application Discontinuation
- 2002-08-05 WO PCT/EP2002/008700 patent/WO2003014085A1/en not_active Ceased
- 2002-08-05 CN CNB028155114A patent/CN100494175C/zh not_active Expired - Fee Related
- 2002-08-05 HU HU0401161A patent/HUP0401161A3/hu unknown
- 2002-08-05 DE DE60203919T patent/DE60203919D1/de not_active Expired - Lifetime
- 2002-08-05 IL IL15391602A patent/IL153916A0/xx unknown
- 2002-08-05 EA EA200400279A patent/EA200400279A1/ru unknown
- 2002-08-05 AT AT02767318T patent/ATE294162T1/de not_active IP Right Cessation
- 2002-08-05 MX MXPA04001073A patent/MXPA04001073A/es not_active Application Discontinuation
- 2002-08-05 ES ES02767318T patent/ES2209684T1/es active Pending
- 2002-08-05 KR KR1020047001791A patent/KR100912664B1/ko not_active Expired - Fee Related
- 2002-08-05 AU AU2002331390A patent/AU2002331390B2/en not_active Ceased
- 2002-08-05 HR HR20040157A patent/HRP20040157A2/hr not_active Application Discontinuation
- 2002-08-05 EP EP02767318A patent/EP1423367B1/de not_active Expired - Lifetime
- 2002-08-05 PL PL02369449A patent/PL369449A1/xx unknown
- 2002-08-05 JP JP2003519035A patent/JP2005502648A/ja active Pending
- 2002-08-05 BR BR0211738-0A patent/BR0211738A/pt not_active IP Right Cessation
- 2002-08-06 PE PE2002000716A patent/PE20030350A1/es not_active Application Discontinuation
- 2002-08-06 UY UY27409A patent/UY27409A1/es not_active Application Discontinuation
-
2003
- 2003-01-13 IL IL153916A patent/IL153916A/en unknown
-
2004
- 2004-02-03 NO NO20040479A patent/NO20040479L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20040479L (no) | 2004-02-03 |
| IL153916A0 (en) | 2003-07-31 |
| EA200400279A1 (ru) | 2004-06-24 |
| KR20040030932A (ko) | 2004-04-09 |
| EP1423367B1 (de) | 2005-04-27 |
| AR037230A1 (es) | 2004-11-03 |
| HRP20040157A2 (en) | 2004-08-31 |
| UY27409A1 (es) | 2003-03-31 |
| KR100912664B1 (ko) | 2009-08-17 |
| ITMI20011727A0 (it) | 2001-08-06 |
| MXPA04001073A (es) | 2005-02-17 |
| ITMI20011727A1 (it) | 2003-02-06 |
| PL369449A1 (en) | 2005-04-18 |
| HUP0401161A2 (hu) | 2004-09-28 |
| PE20030350A1 (es) | 2003-06-06 |
| ES2209684T1 (es) | 2004-07-01 |
| AU2002331390B2 (en) | 2008-06-05 |
| CN1538958A (zh) | 2004-10-20 |
| IL153916A (en) | 2008-07-08 |
| DE60203919D1 (de) | 2005-06-02 |
| EP1423367A1 (de) | 2004-06-02 |
| HUP0401161A3 (en) | 2009-04-28 |
| CN100494175C (zh) | 2009-06-03 |
| WO2003014085A1 (en) | 2003-02-20 |
| BR0211738A (pt) | 2004-09-28 |
| JP2005502648A (ja) | 2005-01-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE437871T1 (de) | Polymorphe formen von 1-ä4-(5-cyanoindol-3- yl)butylü-4-(2-carbamoylbenzofuran-5-yl) piperazin-hydrochlorid | |
| CY2017030I2 (el) | Παραγωγα πυρρολιδινης και πιπεριδινης ως ανταγωνιστες νκ1 | |
| DK1227088T3 (da) | Krystallinsk base af citalopram og hydrochlorid- eller hydrobromidsaltet deraf | |
| IS7216A (is) | Bensamíð og heteróarýlamíð sem P2X7 viðtaka mótlyf | |
| DE60122196D1 (de) | Synergistische antioxidans-kombination von delta tocols und polyphenolen | |
| DE60227301D1 (de) | Strukturen von anschlusselementen und anzuschliessende komponente | |
| DE60217458D1 (de) | Massenspektrometer und Verfahren | |
| EP1420825A4 (de) | Immunmodulatorische verbindungen und verwendungszwecke dafür | |
| NO20030471D0 (no) | Karboksamidforbindelser og deres anvendelse som antagonister for en 11CBY-reseptor | |
| FI20011193L (fi) | Menetelmä päätelaitteen akustisten ominaisuuksien parantamiseksi ja päätelaite | |
| DE60220486D1 (de) | Zurückschaltungseinrichtung und Zurückschaltungsverfahren | |
| DE60210535D1 (de) | Vibrator und Herstellungsverfahren desselben | |
| ATE495169T1 (de) | Toluol-solvat von darifenacin | |
| ATE307114T1 (de) | Kristalline polymorphe formen von lercanidipin hydrochlorid und verfahren zu deren herstellung | |
| EP1455841A4 (de) | Osteopontin-verwandte zusammensetzungen und verfahren | |
| DE60203919D1 (de) | Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid | |
| IS6797A (is) | Ný kristal- og lausnarsambandsform ondansetrónvetnisklóríðs og aðferðir við að framleiða þau | |
| NO20032091D0 (no) | Blandinger av N-(metyletylaminokarbonyl)-4-(3- metylfenylamino)-3-pyridylsulfonamid og sykliske oligosakkarider | |
| EP1468113A4 (de) | Optineurin und glaukom | |
| DE60109730D1 (de) | Zementzusatzmittel und Zementzusammensetzung | |
| DE60238302D1 (de) | Piezoelektrischer vibrator und filter der denselben verwendet | |
| DK1440067T3 (da) | N-formyl-derivater af paroxetin | |
| DE50115118D1 (de) | Mikromechanisches bauelement und abgleichverfahren | |
| ATA19992001A (de) | Einrichtung zum trockenlegen von mauerwerk und fundamenten | |
| DE60122663D1 (de) | Verbesserte Schärmaschine und Schärverfahren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |