UY27409A1 - Solvatos de clorhidrato de lercanidipina y novedosas formas cristalinas de ellos - Google Patents
Solvatos de clorhidrato de lercanidipina y novedosas formas cristalinas de ellosInfo
- Publication number
- UY27409A1 UY27409A1 UY27409A UY27409A UY27409A1 UY 27409 A1 UY27409 A1 UY 27409A1 UY 27409 A UY27409 A UY 27409A UY 27409 A UY27409 A UY 27409A UY 27409 A1 UY27409 A1 UY 27409A1
- Authority
- UY
- Uruguay
- Prior art keywords
- lercanidipine
- solvatos
- novedous
- chlorhydrate
- crystal forms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención describe solvatos de clorhidrato de lercanidipina novedosos con solventes orgánicos, nuevas formas cristalinas (III) y (IV) de clorhidrato de lercanidipina que se obtienen a partir de dichos solvatos mediante la eliminación de los solventes de solvatación y describe, también, composiciones farmacéuticas que contienen por lo menos una de dichas formas cristalinas (III) y (IV) de clorhidrato de lercanidipina, como agente activo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001MI001727A ITMI20011727A1 (it) | 2001-08-06 | 2001-08-06 | Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi |
Publications (1)
Publication Number | Publication Date |
---|---|
UY27409A1 true UY27409A1 (es) | 2003-03-31 |
Family
ID=11448246
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY27409A UY27409A1 (es) | 2001-08-06 | 2002-08-06 | Solvatos de clorhidrato de lercanidipina y novedosas formas cristalinas de ellos |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1423367B1 (es) |
JP (1) | JP2005502648A (es) |
KR (1) | KR100912664B1 (es) |
CN (1) | CN100494175C (es) |
AR (1) | AR037230A1 (es) |
AT (1) | ATE294162T1 (es) |
AU (1) | AU2002331390B2 (es) |
BR (1) | BR0211738A (es) |
DE (1) | DE60203919D1 (es) |
EA (1) | EA200400279A1 (es) |
ES (1) | ES2209684T1 (es) |
HR (1) | HRP20040157A2 (es) |
HU (1) | HUP0401161A3 (es) |
IL (2) | IL153916A0 (es) |
IT (1) | ITMI20011727A1 (es) |
MX (1) | MXPA04001073A (es) |
NO (1) | NO20040479L (es) |
PE (1) | PE20030350A1 (es) |
PL (1) | PL369449A1 (es) |
UY (1) | UY27409A1 (es) |
WO (1) | WO2003014085A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100651212B1 (ko) | 2004-10-27 | 2006-12-01 | 제일약품주식회사 | 무정형 레르카니디핀의 제조방법 |
AR052918A1 (es) | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
BRPI0616169B8 (pt) | 2005-09-16 | 2021-05-25 | Glenmark Pharmaceuticals Ltd | cloridrato de lercanidipina na forma polimorfa v, composição farmacêutica compreendendo dito composto e processos para preparação de cloridrato de lercanidipina |
US20100104649A1 (en) * | 2007-03-05 | 2010-04-29 | Actavis Group Ptc Ehf | Lercanidipine Hydrochloride Polymorphs and an Improved Process for Preparation of 1,1,N-Trimethyl-N-(3,3-Diphenylpropyl)-2-Aminoethyl Acetoacetate |
WO2008136393A1 (ja) * | 2007-04-27 | 2008-11-13 | Ajinomoto Co., Inc. | ラクタム化合物の結晶形およびその製造方法 |
EP2585051B2 (en) | 2010-06-23 | 2020-04-08 | KRKA, tovarna zdravil, d.d., Novo mesto | Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts |
EP2654729B1 (en) | 2010-12-24 | 2016-05-04 | KRKA, d.d., Novo mesto | Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts together with an organic acid |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8403866D0 (en) * | 1984-02-14 | 1984-03-21 | Recordati Chem Pharm | Diphenylalkylaminoalkyl esters |
US5912351A (en) * | 1995-05-12 | 1999-06-15 | Recordati, S.A. Chemical And Pharmaceutical Company | Anhydrous 1,4-Dihydropyridines and salts thereof |
-
2001
- 2001-08-06 IT IT2001MI001727A patent/ITMI20011727A1/it unknown
-
2002
- 2002-08-02 AR ARP020102957A patent/AR037230A1/es not_active Application Discontinuation
- 2002-08-05 CN CNB028155114A patent/CN100494175C/zh not_active Expired - Fee Related
- 2002-08-05 AU AU2002331390A patent/AU2002331390B2/en not_active Ceased
- 2002-08-05 AT AT02767318T patent/ATE294162T1/de not_active IP Right Cessation
- 2002-08-05 KR KR1020047001791A patent/KR100912664B1/ko not_active IP Right Cessation
- 2002-08-05 JP JP2003519035A patent/JP2005502648A/ja active Pending
- 2002-08-05 MX MXPA04001073A patent/MXPA04001073A/es not_active Application Discontinuation
- 2002-08-05 HU HU0401161A patent/HUP0401161A3/hu unknown
- 2002-08-05 DE DE60203919T patent/DE60203919D1/de not_active Expired - Lifetime
- 2002-08-05 EP EP02767318A patent/EP1423367B1/en not_active Expired - Lifetime
- 2002-08-05 PL PL02369449A patent/PL369449A1/xx unknown
- 2002-08-05 WO PCT/EP2002/008700 patent/WO2003014085A1/en active IP Right Grant
- 2002-08-05 IL IL15391602A patent/IL153916A0/xx unknown
- 2002-08-05 EA EA200400279A patent/EA200400279A1/ru unknown
- 2002-08-05 ES ES02767318T patent/ES2209684T1/es active Pending
- 2002-08-05 BR BR0211738-0A patent/BR0211738A/pt not_active IP Right Cessation
- 2002-08-06 UY UY27409A patent/UY27409A1/es not_active Application Discontinuation
- 2002-08-06 PE PE2002000716A patent/PE20030350A1/es not_active Application Discontinuation
-
2003
- 2003-01-13 IL IL153916A patent/IL153916A/en unknown
-
2004
- 2004-02-03 NO NO20040479A patent/NO20040479L/no not_active Application Discontinuation
- 2004-02-18 HR HR20040157A patent/HRP20040157A2/hr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PE20030350A1 (es) | 2003-06-06 |
ITMI20011727A0 (it) | 2001-08-06 |
AR037230A1 (es) | 2004-11-03 |
EP1423367A1 (en) | 2004-06-02 |
WO2003014085A1 (en) | 2003-02-20 |
ATE294162T1 (de) | 2005-05-15 |
CN1538958A (zh) | 2004-10-20 |
ES2209684T1 (es) | 2004-07-01 |
EP1423367B1 (en) | 2005-04-27 |
ITMI20011727A1 (it) | 2003-02-06 |
PL369449A1 (en) | 2005-04-18 |
EA200400279A1 (ru) | 2004-06-24 |
AU2002331390B2 (en) | 2008-06-05 |
DE60203919D1 (de) | 2005-06-02 |
HUP0401161A3 (en) | 2009-04-28 |
IL153916A0 (en) | 2003-07-31 |
KR20040030932A (ko) | 2004-04-09 |
IL153916A (en) | 2008-07-08 |
HRP20040157A2 (en) | 2004-08-31 |
HUP0401161A2 (hu) | 2004-09-28 |
KR100912664B1 (ko) | 2009-08-17 |
NO20040479L (no) | 2004-02-03 |
JP2005502648A (ja) | 2005-01-27 |
BR0211738A (pt) | 2004-09-28 |
CN100494175C (zh) | 2009-06-03 |
MXPA04001073A (es) | 2005-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20150126 |