DE60203919D1 - Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid - Google Patents

Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid

Info

Publication number
DE60203919D1
DE60203919D1 DE60203919T DE60203919T DE60203919D1 DE 60203919 D1 DE60203919 D1 DE 60203919D1 DE 60203919 T DE60203919 T DE 60203919T DE 60203919 T DE60203919 T DE 60203919T DE 60203919 D1 DE60203919 D1 DE 60203919D1
Authority
DE
Germany
Prior art keywords
lercanidipine hydrochloride
solvates
crystalline forms
lercanidipine
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60203919T
Other languages
English (en)
Inventor
Amedeo Leonardi
Iasi Gianluca De
Fausto Bonifacio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati Ireland Ltd
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Application granted granted Critical
Publication of DE60203919D1 publication Critical patent/DE60203919D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60203919T 2001-08-06 2002-08-05 Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid Expired - Lifetime DE60203919D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001MI001727A ITMI20011727A1 (it) 2001-08-06 2001-08-06 Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi
PCT/EP2002/008700 WO2003014085A1 (en) 2001-08-06 2002-08-05 Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride

Publications (1)

Publication Number Publication Date
DE60203919D1 true DE60203919D1 (de) 2005-06-02

Family

ID=11448246

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60203919T Expired - Lifetime DE60203919D1 (de) 2001-08-06 2002-08-05 Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid

Country Status (21)

Country Link
EP (1) EP1423367B1 (de)
JP (1) JP2005502648A (de)
KR (1) KR100912664B1 (de)
CN (1) CN100494175C (de)
AR (1) AR037230A1 (de)
AT (1) ATE294162T1 (de)
AU (1) AU2002331390B2 (de)
BR (1) BR0211738A (de)
DE (1) DE60203919D1 (de)
EA (1) EA200400279A1 (de)
ES (1) ES2209684T1 (de)
HR (1) HRP20040157A2 (de)
HU (1) HUP0401161A3 (de)
IL (2) IL153916A0 (de)
IT (1) ITMI20011727A1 (de)
MX (1) MXPA04001073A (de)
NO (1) NO20040479L (de)
PE (1) PE20030350A1 (de)
PL (1) PL369449A1 (de)
UY (1) UY27409A1 (de)
WO (1) WO2003014085A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100651212B1 (ko) 2004-10-27 2006-12-01 제일약품주식회사 무정형 레르카니디핀의 제조방법
AR052918A1 (es) 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
US8097729B2 (en) 2005-09-16 2012-01-17 Glenmark Generics Ltd. Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof
EP2121575A2 (de) * 2007-03-05 2009-11-25 Actavis Group PTC EHF Lercanidipin-hydrochlorid-polymorphe und verbessertes verfahren zur herstellung von 1,1,n-trimethyl-n-(3,3-diphenylpropyl)-2-amino-ethylacetoacetat
WO2008136394A1 (ja) * 2007-04-27 2008-11-13 Ajinomoto Co., Inc. ラクタム化合物の製造方法及びその製造中間体
EP2585051B2 (de) 2010-06-23 2020-04-08 KRKA, tovarna zdravil, d.d., Novo mesto Pharmazeutische orale dosierformen mit lercandipin und enalapril und ihren pharmazeutisch akzeptablen salzen
EP2654729B1 (de) 2010-12-24 2016-05-04 KRKA, d.d., Novo mesto Orale homogene pharmazeutische zubereitung enthaltend lercanidipine und enalapril oder ihre pharmazeutische salze zusammen mit einer organischen säure

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
US5912351A (en) * 1995-05-12 1999-06-15 Recordati, S.A. Chemical And Pharmaceutical Company Anhydrous 1,4-Dihydropyridines and salts thereof

Also Published As

Publication number Publication date
MXPA04001073A (es) 2005-02-17
PE20030350A1 (es) 2003-06-06
JP2005502648A (ja) 2005-01-27
WO2003014085A1 (en) 2003-02-20
IL153916A0 (en) 2003-07-31
EA200400279A1 (ru) 2004-06-24
KR100912664B1 (ko) 2009-08-17
AU2002331390B2 (en) 2008-06-05
AR037230A1 (es) 2004-11-03
NO20040479L (no) 2004-02-03
ES2209684T1 (es) 2004-07-01
ITMI20011727A1 (it) 2003-02-06
EP1423367A1 (de) 2004-06-02
HRP20040157A2 (en) 2004-08-31
UY27409A1 (es) 2003-03-31
CN1538958A (zh) 2004-10-20
CN100494175C (zh) 2009-06-03
HUP0401161A2 (hu) 2004-09-28
ITMI20011727A0 (it) 2001-08-06
BR0211738A (pt) 2004-09-28
HUP0401161A3 (en) 2009-04-28
EP1423367B1 (de) 2005-04-27
PL369449A1 (en) 2005-04-18
KR20040030932A (ko) 2004-04-09
IL153916A (en) 2008-07-08
ATE294162T1 (de) 2005-05-15

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Legal Events

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