BR0211738A - Solvatos de cloridrato de lecandipina e novas formas cristalinas de cloridrato de lecandipina obtidas dos ditos solvatos - Google Patents
Solvatos de cloridrato de lecandipina e novas formas cristalinas de cloridrato de lecandipina obtidas dos ditos solvatosInfo
- Publication number
- BR0211738A BR0211738A BR0211738-0A BR0211738A BR0211738A BR 0211738 A BR0211738 A BR 0211738A BR 0211738 A BR0211738 A BR 0211738A BR 0211738 A BR0211738 A BR 0211738A
- Authority
- BR
- Brazil
- Prior art keywords
- solvates
- lecandipine
- hydrochloride
- crystalline forms
- new crystalline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"SOLVATOS DE CLORIDRATO DE LERCANDIPINA E NOVAS FORMAS CRISTALINAS DE CLORIDRATO DE LERCANDIPINA OBTIDAS DOS DITOS SOLVATOS". A presente invenção descreve novos solvatos de cloridrato de lercanidipina com solventes orgânicos, novas Formas cristalinas (III) e (IV) de cloridrato de lercanidipina obtidas dos ditos solvatos mediante remoção dos solventes de solvatação e composições farmacêuticas contendo como agente ativo pelo menos uma das Formas cristalinas (III) e (IV) de cloridrato de lercanidipina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001MI001727A ITMI20011727A1 (it) | 2001-08-06 | 2001-08-06 | Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi |
| PCT/EP2002/008700 WO2003014085A1 (en) | 2001-08-06 | 2002-08-05 | Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0211738A true BR0211738A (pt) | 2004-09-28 |
Family
ID=11448246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0211738-0A BR0211738A (pt) | 2001-08-06 | 2002-08-05 | Solvatos de cloridrato de lecandipina e novas formas cristalinas de cloridrato de lecandipina obtidas dos ditos solvatos |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1423367B1 (pt) |
| JP (1) | JP2005502648A (pt) |
| KR (1) | KR100912664B1 (pt) |
| CN (1) | CN100494175C (pt) |
| AR (1) | AR037230A1 (pt) |
| AT (1) | ATE294162T1 (pt) |
| AU (1) | AU2002331390B2 (pt) |
| BR (1) | BR0211738A (pt) |
| DE (1) | DE60203919D1 (pt) |
| EA (1) | EA200400279A1 (pt) |
| ES (1) | ES2209684T1 (pt) |
| HR (1) | HRP20040157A2 (pt) |
| HU (1) | HUP0401161A3 (pt) |
| IL (2) | IL153916A0 (pt) |
| IT (1) | ITMI20011727A1 (pt) |
| MX (1) | MXPA04001073A (pt) |
| NO (1) | NO20040479L (pt) |
| PE (1) | PE20030350A1 (pt) |
| PL (1) | PL369449A1 (pt) |
| UY (1) | UY27409A1 (pt) |
| WO (1) | WO2003014085A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100651212B1 (ko) | 2004-10-27 | 2006-12-01 | 제일약품주식회사 | 무정형 레르카니디핀의 제조방법 |
| AR052918A1 (es) | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
| WO2007031865A2 (en) * | 2005-09-16 | 2007-03-22 | Glenmark Pharmaceuticals Limited | Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof |
| EP2121575A2 (en) * | 2007-03-05 | 2009-11-25 | Actavis Group PTC EHF | Lercanidipine hydrochloride polymorphs and an improved process for preparation of 1,1,n-trimethyl-n-(3,3-diphenylpropyl)-2-aminoethyl acetoacetate |
| WO2008136393A1 (ja) * | 2007-04-27 | 2008-11-13 | Ajinomoto Co., Inc. | ラクタム化合物の結晶形およびその製造方法 |
| WO2011161223A2 (en) | 2010-06-23 | 2011-12-29 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts |
| SI2654729T1 (sl) | 2010-12-24 | 2016-08-31 | Krka, D.D., Novo Mesto | Homogene farmacevtske oralne dozirne oblike, ki obsegajo lerkanidipin in enalapril ali njune farmacevtsko sprejemljive soli skupaj z organsko kislino |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8403866D0 (en) * | 1984-02-14 | 1984-03-21 | Recordati Chem Pharm | Diphenylalkylaminoalkyl esters |
| US5912351A (en) | 1995-05-12 | 1999-06-15 | Recordati, S.A. Chemical And Pharmaceutical Company | Anhydrous 1,4-Dihydropyridines and salts thereof |
-
2001
- 2001-08-06 IT IT2001MI001727A patent/ITMI20011727A1/it unknown
-
2002
- 2002-08-02 AR ARP020102957A patent/AR037230A1/es not_active Application Discontinuation
- 2002-08-05 IL IL15391602A patent/IL153916A0/xx unknown
- 2002-08-05 DE DE60203919T patent/DE60203919D1/de not_active Expired - Lifetime
- 2002-08-05 MX MXPA04001073A patent/MXPA04001073A/es not_active Application Discontinuation
- 2002-08-05 EA EA200400279A patent/EA200400279A1/ru unknown
- 2002-08-05 JP JP2003519035A patent/JP2005502648A/ja active Pending
- 2002-08-05 WO PCT/EP2002/008700 patent/WO2003014085A1/en active IP Right Grant
- 2002-08-05 BR BR0211738-0A patent/BR0211738A/pt not_active IP Right Cessation
- 2002-08-05 PL PL02369449A patent/PL369449A1/xx unknown
- 2002-08-05 CN CNB028155114A patent/CN100494175C/zh not_active Expired - Fee Related
- 2002-08-05 HU HU0401161A patent/HUP0401161A3/hu unknown
- 2002-08-05 AU AU2002331390A patent/AU2002331390B2/en not_active Ceased
- 2002-08-05 EP EP02767318A patent/EP1423367B1/en not_active Expired - Lifetime
- 2002-08-05 KR KR1020047001791A patent/KR100912664B1/ko not_active IP Right Cessation
- 2002-08-05 AT AT02767318T patent/ATE294162T1/de not_active IP Right Cessation
- 2002-08-05 ES ES02767318T patent/ES2209684T1/es active Pending
- 2002-08-06 PE PE2002000716A patent/PE20030350A1/es not_active Application Discontinuation
- 2002-08-06 UY UY27409A patent/UY27409A1/es not_active Application Discontinuation
-
2003
- 2003-01-13 IL IL153916A patent/IL153916A/en unknown
-
2004
- 2004-02-03 NO NO20040479A patent/NO20040479L/no not_active Application Discontinuation
- 2004-02-18 HR HR20040157A patent/HRP20040157A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI20011727A1 (it) | 2003-02-06 |
| MXPA04001073A (es) | 2005-02-17 |
| AR037230A1 (es) | 2004-11-03 |
| PL369449A1 (en) | 2005-04-18 |
| EP1423367A1 (en) | 2004-06-02 |
| IL153916A0 (en) | 2003-07-31 |
| KR20040030932A (ko) | 2004-04-09 |
| UY27409A1 (es) | 2003-03-31 |
| KR100912664B1 (ko) | 2009-08-17 |
| JP2005502648A (ja) | 2005-01-27 |
| ITMI20011727A0 (it) | 2001-08-06 |
| EA200400279A1 (ru) | 2004-06-24 |
| IL153916A (en) | 2008-07-08 |
| NO20040479L (no) | 2004-02-03 |
| AU2002331390B2 (en) | 2008-06-05 |
| CN100494175C (zh) | 2009-06-03 |
| HUP0401161A3 (en) | 2009-04-28 |
| ES2209684T1 (es) | 2004-07-01 |
| ATE294162T1 (de) | 2005-05-15 |
| HRP20040157A2 (en) | 2004-08-31 |
| DE60203919D1 (de) | 2005-06-02 |
| EP1423367B1 (en) | 2005-04-27 |
| PE20030350A1 (es) | 2003-06-06 |
| WO2003014085A1 (en) | 2003-02-20 |
| CN1538958A (zh) | 2004-10-20 |
| HUP0401161A2 (hu) | 2004-09-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1073470E (pt) | Composicoes farmaceuticas contendo compostos com actividade capaz de melhorar a absorcao de ingredientes activos | |
| NO20054787D0 (no) | Indenderivater som farmasotiske midler | |
| BRPI0409945A (pt) | forma de dosagem resistente à alteração | |
| NO20042739L (no) | Farmasoytiske sammensetninger av 5,6,14-triazatetracyklo(10.3.1.0(2,11).0(4,9))-heksadeca-2(11)3,5,7,9-pentan | |
| DE69529670T2 (de) | Oxazolidinon derivate und diese enthaltende pharmazeutische zusammensetzungen | |
| DE60238255D1 (de) | Azolsäure-derivate, allein oder kombiniert, zur behandlung von diabetes und dyslipidaemien; und zur behandlung von malignen erkrankungen | |
| EA200401169A1 (ru) | Аминометилзамещенные тетрациклиновые соединения | |
| EA200600602A1 (ru) | Синергические фунгицидные комбинации биологически активных веществ | |
| ECSP044997A (es) | DERIVADOS SUSTITUIDOS DEL INDENO [1,2-c] ISOQUINOLINA | |
| EA200401526A1 (ru) | Новые соединения и их применение | |
| ATE413388T1 (de) | Muskarin antagonisten | |
| BR0211739A (pt) | Novas formas polimórficas cristalinas de cloridrato de lercanidipina e processo para preparação das mesmas | |
| ATE386725T1 (de) | Heterocyclylverbindungen | |
| ES2186550A1 (es) | Nuevos derivados de oxazolidinonas como antibacterianos. | |
| NO20040881L (no) | Orale antidiabetes midler. | |
| EA200300450A1 (ru) | Фармацевтические растворы соединений модафинила | |
| EA200300597A1 (ru) | Бифенилкарбоксамиды, полезные в качестве снижающих содержание липидов агентов | |
| BR0012696A (pt) | Composição oftálmica | |
| HUP0103203A2 (hu) | Azaadamantánszármazékok és ezeket tartalmazó gyógyszerkészítmények | |
| BR0211738A (pt) | Solvatos de cloridrato de lecandipina e novas formas cristalinas de cloridrato de lecandipina obtidas dos ditos solvatos | |
| SE0003476D0 (sv) | Compounds | |
| DE69805165D1 (de) | Isocyanat-vernetzbare, wässrige zusammensetzungen niedrigen gehalts an flüchtigen organischen verbindungen | |
| EA200300727A1 (ru) | Производные 2h-1-бензопирана, способы их получения и их фармацевтические композиции | |
| ATE373644T1 (de) | N-substituierte 3-hydroxy-4-pyridinone und diese enthaltende pharmazeutika | |
| TR199901017A2 (xx) | B�cek ilac� terkibi. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08L | Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette] |
Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 10A E 11A ANUIDADES. |
|
| B08I | Publication cancelled [chapter 8.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2258 DE 15/04/2014 POR TER SIDO INDEVIDA. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 10A, 11A, 12A, 13A, 14A, 15A, 16A, 17A E 18A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |