ATE293958T1 - Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle - Google Patents

Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle

Info

Publication number
ATE293958T1
ATE293958T1 AT98932506T AT98932506T ATE293958T1 AT E293958 T1 ATE293958 T1 AT E293958T1 AT 98932506 T AT98932506 T AT 98932506T AT 98932506 T AT98932506 T AT 98932506T AT E293958 T1 ATE293958 T1 AT E293958T1
Authority
AT
Austria
Prior art keywords
microparticles
biologically active
controlled delivery
active molecules
synthetic
Prior art date
Application number
AT98932506T
Other languages
German (de)
English (en)
Inventor
Jenny Cowdall
John Davies
Mark Roberts
Anders Carlsson
Roberto Solaro
Giuseppe Mazzanti
Elisabetta Chiellini
Federica Chiellini
Erik Soederlind
Original Assignee
Isi Ist Sierovaccinogeno Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isi Ist Sierovaccinogeno Ital filed Critical Isi Ist Sierovaccinogeno Ital
Application granted granted Critical
Publication of ATE293958T1 publication Critical patent/ATE293958T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98932506T 1997-07-10 1998-07-09 Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle ATE293958T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97RM000418A IT1293088B1 (it) 1997-07-10 1997-07-10 Microparticelle per il rilascio controllato di molecole biologicamente attive e loro uso in terapia, profilassi e diagnostica in vitro e in
PCT/IT1998/000192 WO1999002135A1 (en) 1997-07-10 1998-07-09 Microparticles for controlled delivery of biologically active molecules

Publications (1)

Publication Number Publication Date
ATE293958T1 true ATE293958T1 (de) 2005-05-15

Family

ID=11405168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98932506T ATE293958T1 (de) 1997-07-10 1998-07-09 Mikropartikel zur gesteuerten wirkstoffabgabe biologisch aktiver moleküle

Country Status (7)

Country Link
EP (1) EP1003482B1 (US06559137-20030506-C00182.png)
AT (1) ATE293958T1 (US06559137-20030506-C00182.png)
AU (1) AU8240998A (US06559137-20030506-C00182.png)
DE (1) DE69829975T2 (US06559137-20030506-C00182.png)
ES (1) ES2242287T3 (US06559137-20030506-C00182.png)
IT (1) IT1293088B1 (US06559137-20030506-C00182.png)
WO (1) WO1999002135A1 (US06559137-20030506-C00182.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008067717A (ja) * 2001-06-20 2008-03-27 Dainippon Sumitomo Pharma Co Ltd 核酸導入を促進させる方法
CN1313158C (zh) 2001-06-20 2007-05-02 大日本住友制药株式会社 促进核酸转移的方法
US7186692B2 (en) 2002-12-17 2007-03-06 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity
MXPA05006572A (es) 2002-12-17 2005-12-14 Nastech Pharm Co Composiciones y metodos para la administracion mejorada por via mucosa de peptidos fijadores al receptor de y2 y metodos para tratar y prevenir la obesidad.
US7229966B2 (en) 2002-12-17 2007-06-12 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity
US7166575B2 (en) 2002-12-17 2007-01-23 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity
WO2017077066A1 (en) 2015-11-06 2017-05-11 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Composition comprising a biocompatible and biodegradable polymer, nanocarries and a drug and methods of making and using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2660556B1 (fr) * 1990-04-06 1994-09-16 Rhone Poulenc Sante Microspheres, leur procede de preparation et leur utilisation.
IT1244511B (it) * 1991-04-15 1994-07-15 Isi Ist Sierovaccinogeno Ital Idrogeli a base di policarbossilati sintetici e proteine per il rilascio controllato di farmaci e procedimento per la loro preparazione.
DK0644771T4 (da) * 1992-06-11 2006-12-27 Alkermes Inc Lægemiddelsystem til levering af erythropoietin
NZ265818A (en) * 1993-04-19 1997-09-22 Medisorb Technologies Internat Compositions of nucleic acids encapsulated with molecules that facilitate uptake and integration into living cells

Also Published As

Publication number Publication date
IT1293088B1 (it) 1999-02-11
EP1003482A1 (en) 2000-05-31
ITRM970418A1 (it) 1999-01-10
ITRM970418A0 (US06559137-20030506-C00182.png) 1997-07-10
DE69829975D1 (de) 2005-06-02
ES2242287T3 (es) 2005-11-01
WO1999002135A1 (en) 1999-01-21
EP1003482B1 (en) 2005-04-27
DE69829975T2 (de) 2006-03-09
AU8240998A (en) 1999-02-08

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Legal Events

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